Science Daily - Heart Disease
NOVEMBER 21, 2024
After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.
Medical Xpress - Cardiology
NOVEMBER 21, 2024
A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single "aberrant" genetic variant, as was previously thought, finds a new study led by researchers at UCL (University College London), Imperial College London and the MRC Laboratory of Medical Sciences.
Science Daily - Heart Disease
NOVEMBER 21, 2024
Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the door to better ways to manage high blood pressure and other vascular diseases.
Medical Xpress - Cardiology
NOVEMBER 21, 2024
After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart. This is according to a new study from Karolinska Institutet published in the journal Circulation.
Med Page Today
NOVEMBER 21, 2024
(MedPage Today) -- FDA advisors pushed for nuance in discussing whether andexanet alfa (Andexxa) should gain full approval, citing uncertainties about which dose and in which patients it could be best used to stop bleeding. Members of the Cellular.
Circulation
NOVEMBER 21, 2024
Circulation, Ahead of Print. Right ventricular outflow dysfunction, manifesting as stenosis, regurgitation, or both, is nearly universal in patients with repaired tetralogy of Fallot, precipitating a complex pathophysiological cascade that leads to increasing rates of morbidity and mortality with advancing age. As the number of adolescent and adult patients with repaired tetralogy of Fallot continues to grow as a result of excellent survival during infancy, the need to improve late outcomes has
Dr. Smith's ECG Blog
NOVEMBER 21, 2024
Written by Pendell Meyers A woman in her 40s presented with acute chest pain and shortness of breath. Vitals were within normal limits. Here is her triage ECG: What do you think? Smith : This is classic for pulmonary embolism (PE). There are 2 key points to making this diagnosis on the ECG: 1) There is T-wave inversion which you might think is due to Wellens' waves, but the patient has active symptoms, so it is not Wellens' sydrome 2) The T-wave inversion in V1-V4 is accompanied by T-wave invers
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Science Daily - Heart Disease
NOVEMBER 21, 2024
Drug discovery researchers have found that a natural fat molecule called 'lipoxin A4' (LXA4) could significantly reduce inflammation and improve function for diabetic hearts.
HCPLive
NOVEMBER 21, 2024
Ahmad Masri, MD, MS, discusses a study from AHA 2024 detailing changing risk profiles and outcomes in trials among patients with ATTR-CM.
Medical Xpress - Cardiology
NOVEMBER 21, 2024
A drug used to help patients lose weight and manage diabetes may also help those with heart failure, an international clinical trial shows.
Science Daily - Heart Disease
NOVEMBER 21, 2024
A potentially life-changing heart condition, dilated cardiomyopathy, can be caused by the cumulative influence of hundreds or thousands of genes and not just by a single 'aberrant' genetic variant, as was previously thought, finds a new study.
Journal of Cardiothoracic Surgery
NOVEMBER 21, 2024
As the current guidelines on myocardial revascularization recommend, transit-time flow measurement (TTFM) is increasingly used for intraoperative graft flow analysis during coronary artery bypass grafting (CAB.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundAnomalous aortic origin of a coronary artery (AAOCA) is associated with an increased risk of myocardial ischemia and sudden cardiac death. This study aims to evaluate the medium-term outcomes of surgical repair for AAOCA and to introduce a novel off-pump technique for anomalous coronary artery reimplantation.MethodsWe retrospectively reviewed the medical records of 12 patients aged 12 years and older who underwent AAOCA surgery at Fuwai Hospital between 2009 and 2016.ResultsThe median
Becker's Hospital Review - Cardiology
NOVEMBER 21, 2024
Baylor College of Medicine and the Texas Heart Institute, both based in Houston, will partner to establish a cardiovascular health and research center at Baylor St. Luke's Medical Center.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
Fabry disease (FD) is a rare X-linked inherited lysosomal storage disorder. The abnormal accumulation of metabolic substrates induces inflammation and fibrosis in cells, resulting in organ dysfunction. The clinical manifestations of FD are diverse and non-specific. In the present study, we report a case initially treated as obstructive hypertrophic cardiomyopathy for several years, which was finally identified as FD through whole-exome sequencing (WES).
DAIC
NOVEMBER 21, 2024
tim.hodson Thu, 11/21/2024 - 13:27 Nov. 21, 2024 — Royal Philips plans to unveil its next-generation 1.5T BlueSeal MR wide-bore scanner at RSNA 2024 in Chicago, Dec. 1-4. The latest generation scanner features a 70 cm wide-bore design and integrates AI-enabled MR Smart Workflow solutions, designed to enhance access and diagnostic confidence to improve outcomes for more patients.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundFollowing the identification of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, research in this area has experienced significant growth. However, a thorough bibliometric analysis of this burgeoning field remains conspicuously absent. The current study aims to delineate research hotspots and anticipate future trends on PCSK9 inhibitors employing bibliometric analysis.MethodsA systematic search was conducted in the Web of Science Core Collection (WoSCC) to identify sch
AMS Cardiology
NOVEMBER 21, 2024
While the holidays themselves can’t cause a heart attack , certain things people do during the hectic, festive season may stress their heart health more than they realize. Heart attacks and other cardiac events, such as heart failure flare-ups and “holiday heart syndrome” – a term used to describe palpitations induced by alcohol consumption – often surge during the winter holidays.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
Coronary artery fistulas (CAFs) are rare congenital heart defects that are typically managed through interventional closure, traditional surgery, or minimally invasive hybrid closure surgery. However, treating CAFs with complex anatomy, such as tortuous vessels, presents a significant challenge, particularly in young children. We report the case of a 3.8-year-old child (15 kg/100 cm) with a complex CAF, treated using a minimally invasive hybrid closure surgery approach with a 4 × 4 mm Amplatz
Becker's Hospital Review - Cardiology
NOVEMBER 21, 2024
Arizona, Louisiana, Michigan, Ohio, Pennsylvania and Texas have the most top-ranked hospitals for heart valve replacement in the U.S., according to the WebMD Choice Awards.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
Background and aimEstimated glomerular filtration rate (eGFR) is a key indicator of kidney function and is associated with numerous health conditions. This study examines the association between eGFR and cardiovascular disease (CVD) risk in a representative cohort of the US adult population.MethodsA cross-sectional analysis was conducted using data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018.
HCPLive
NOVEMBER 21, 2024
Ahmad Masri, MD, MS, discusses data from the FOREST-HCM trial examining effects of aficamten in patients with oHCM eligible for septal reduction therapy at baseline.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
Diabetes mellitus (DM) promotes atherosclerosis, leading to increased risk for cardiovascular morbidity and mortality. Diabetics represent a challenging subset of patients undergoing percutaneous coronary intervention (PCI) or who have experienced an acute coronary syndrome (ACS), a subset characterized by higher rates of recurrent ischemic events compared with non-diabetics.
HCPLive
NOVEMBER 21, 2024
HCPLive spoke with Kastl at NASPGHAN about the team’s study on the immune response to the COVID-19 vaccination among children with IBD.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundHeart failure is a significant worldwide health problem that leads to mortality. Therefore, this study aimed to evaluate treatment outcomes and associated factors of heart failure patients who were admitted to hospitals in the southwest of Ethiopia.Methods and participantsA multicenter prospective observational study was conducted from 1 February to 1 August 2021.
HCPLive
NOVEMBER 21, 2024
Milind Desai, MD describes favorable real-world safety outcomes from mavacamten use over 22 months of the Risk Evaluation and Mitigation Strategy (REMS) program.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
ObjectiveThis study aims to explore the effect of a case management model that breaks through the temporal and spatial characteristics on the at-home phase II exercise rehabilitation of postoperative patients treated with percutaneous coronary intervention (PCI).MethodsWe used the convenience sampling method to select 103 patients with coronary artery disease (53 in the observation group and 50 in the control group) who were admitted to the Department of Cardiovascular Internal Medicine at the J
HCPLive
NOVEMBER 21, 2024
In this episode, hosts break down a pair of studies from AHA 2024, BPROAD and SUMMIT, as well as a study in JAMA projecting semaglutide eligibility in US adults.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
IntroductionIn atrial fibrillation (AF) ablation, fluoroscopy has been a standard tool for catheter guidance. However, the combination of electroanatomic mapping systems (EAMs) and intracardiac echocardiography (ICE) now allows for minimal or zero-fluoroscopy procedures. Concurrently, high-power short-duration (HPSD) ablation has emerged as a promising technique, offering enhanced resistive heating while reducing conductive heating.
HCPLive
NOVEMBER 21, 2024
The investigators concluded that chronic psychological stress substantially impacts skin homeostasis and, consequently, skin aging.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundRupture of an abdominal aortic aneurysm (AAA) is a life-threatening emergency, with untreated cases nearing a 100% mortality rate. This case presents a rare complication of AAA rupture with an infected retroperitoneal hematoma, emphasizing the importance of timely diagnosis and a multidisciplinary approach.Case presentationA 59-year-old male presented with lower back pain, fever, and difficulty moving, persisting for three weeks.
HCPLive
NOVEMBER 21, 2024
Lawitz explains issues with traditional FXR agonists for MASH treatment and how FXR314 differs, potentially offering a more safe and efficacious option.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundIt's recognized that stress hyperglycemia ratio (SHR) is considered a significant indicator of poor prognosis in many diseases. However, its role in critically ill patients with acute heart failure (acute HF) remains underexplored.MethodsWe conducted a retrospective cohort study on patients with acute HF included in the Medical Information Mart for Intensive Care IV (MIMIC-IV) version 2.2 database.
HCPLive
NOVEMBER 21, 2024
Loomba reviews safety and efficacy data for the thyroid hormone receptor beta agonist from a phase 2a trial presented at AASLD The Liver Meeting 2024.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
Cardiovascular magnetic (CMR) resonance is a versatile tool for diagnosing cardiovascular diseases. While gadolinium-based contrast agents are the gold standard for identifying myocardial infarction (MI), their use is limited in patients with allergies or impaired kidney function, affecting a significant portion of the MI population. This has led to a growing interest in developing artificial intelligence (AI)-powered CMR techniques for MI detection without contrast agents.
HCPLive
NOVEMBER 21, 2024
Infusion reaction rates and serum level lowering were similar between 120-minute and 60-minute infusion cohorts in the phase 4 AGILE study.
Frontiers in Cardiovascular Medicine
NOVEMBER 21, 2024
BackgroundPeripheral artery disease (PAD) affects millions globally, causing significant morbidity. Traditional treatments like plain old balloon angioplasty (POBA) have limited success due to high restenosis rates. Drug-coated balloon angioplasty (DCBA) has emerged as a promising alternative, locally delivering antiproliferative drugs like paclitaxel to reduce restenosis.
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