Sun.Oct 13, 2024

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Do patients have a “happiness set point?”

Heart Sisters

The best predictor of how happy you'll be several months after a major life event (positive or negative) might be how happy you were before it happened.

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Multiple triglyceride-derived metabolic indices and incident cardiovascular outcomes in patients with type 2 diabetes and coronary heart disease

Cardiovascular Diabetology

Triglyceride (TG) and its related metabolic indices are recognized as important biomarker gauging cardiovascular diseases. This study aimed to explore the association between multiple TG-derived metabolic indi.

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The impact of inflammatory and oxidative stress biomarkers on the sympathetic nervous system in severe coronary atherosclerosis

Frontiers in Cardiovascular Medicine

ObjectiveThe present study aimed at evaluating the association between sympathetic nervous system activation (SNS) and the severity of coronary artery disease (CAD). In addition, we tested the hypothesis that inflammation and oxidative stress influence the SNS activation.MethodsAdult patients with severe CAD scheduled for coronary artery bypass graft (CABG) surgery were enrolled.

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The relationship between serum HDL-cholesterol, cardiovascular disease and mortality in community-based people with type 2 diabetes: the Fremantle Diabetes Study phase 2

Cardiovascular Diabetology

Older general population-based studies found an inverse association between serum HDL-cholesterol and both cardiovascular disease (CVD) events and mortality, but more recent data have suggested a U-shaped rela.

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Association between weekend admission and in-hospital mortality for patients with ischemic heart disease upon surgery treatment

Frontiers in Cardiovascular Medicine

BackgroundThe existence and reasons for the weekend effect in patients with ischemic heart disease (IHD) were not yet fully identified. This study aimed to evaluate whether weekend admission was independently associated with in-hospital mortality and the possible mechanisms associated with the IHD patients.MethodsThe study was a retrospective study, including IHD patients from 2015 to 2023.

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Association between stress hyperglycemia ratio index and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective study using the MIMIC-IV database

Cardiovascular Diabetology

The stress hyperglycemia ratio (SHR) was developed to mitigate the influence of long-term chronic glycemic factors on stress hyperglycemia levels, which are associated with adverse clinical events, particularl.

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Machine learning-based prediction of mortality in acute myocardial infarction with cardiogenic shock

Frontiers in Cardiovascular Medicine

BackgroundIn the ICU, patients with acute myocardial infarction and cardiogenic shock (AMI-CS) often face high mortality rates, making timely and precise mortality risk prediction crucial for clinical decision-making. Despite existing models, machine learning algorithms hold the potential for improved predictive accuracy.MethodsIn this study, a predictive model was developed using the MIMIC-IV database, with external validation performed on the eICU-CRD database.

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Efficacy and safety of anakinra in radiation-induced acute pericarditis: a case report

Frontiers in Cardiovascular Medicine

BackgroundAcute pericarditis represents an inflammatory disease affecting the pericardial layers. In developed countries more than 80% of pericarditis are defined as idiopathic, less frequently they are secondary to other conditions such as infections, rheumatic or systemic inflammatory diseases, cancer, post–cardiac injury syndromes and radiation therapy (RT).Case presentationWe reported a case of a patient with acute pericarditis that occurred a few hours after chest radiation therapy, perform

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Post-COVID-19 Musculoskeletal Pain Often Fulfills Fibromyalgia Criteria

HCPLive

Over 70% of participants with MSK pain after COVID-19 fulfilled ACR fibromyalgia criteria in new research.

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Association between ablation-induced baroreceptor reflex modification and procedure efficacy in patients with atrial fibrillation

Frontiers in Cardiovascular Medicine

BackgroundThe autonomic nervous system (ANS) plays a significant role in atrial fibrillation (AF). Catheter ablation (CA) is a well-established treatment method for AF and significantly affects the ANS, including baroreceptor (BR) function. However, little is known about the changes in BR function caused by radiofrequency (RF) or cryoballoon energy (CB) and its impact on future AF recurrences.PurposeTo assess 1-year efficacy of CA of AF in relation to BR function modification and type of ablatio

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Updates in Using TAVR for Treating Aortic Stenosis, with Linda Gillam, MD, MPH

HCPLive

Linda Gillam, MD, MPH, discusses updates in the management of aortic stenosis, with a focus on use of TAVR.

TAVR 52
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Charge density mapping demonstrates superiority in catheter ablation of post-surgical atrial tachycardias

Frontiers in Cardiovascular Medicine

IntroductionAtrial tachycardia (AT) frequently occurs after cardiac surgery or surgical ablation procedures. The novel charge density-based mapping system (CDM) provides global chamber mapping and can detect crucial pathways of conduction; therefore, it has potential added value in catheter ablation (CA) of post-surgical ATs. We aimed to test the hypothesis that CDM-guided CA procedures are safe, feasible, and may improve outcome compared to conventional sequential 3D mapping (CARTO)-based CA.Me

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Redo aortic arch repair using trifurcated hybrid prosthesis after failed Ascyrus medical dissection stent treatment

Journal of Cardiothoracic Surgery

The management of acute type A aortic dissection (ATAAD) using the Ascyrus Medical Dissection Stent (AMDS) can lead to complications due to the persistence of the false lumen (FL). This case report presents tw.

Stent 40
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Serotonin and Vasovagal Syncope: Too Much of a Good Thing?

HeartRhythm

In this issue of Heart Rhythm, Wu and colleagues investigated the role of serotonin and serotonin-related metabolites in the pathogenesis of vasovagal syncope (14). The understanding of the role of serotonin in the vasovagal reflex began in 1867 when von Bezold and Hirt reported that injections of veratrum alkaloids, which are extracted from Veratrum californicum and V. viride, into animals caused hypotension, bradycardia, and apnea (1).

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Letter by Jha Regarding Article, “mPAP/CO Slope and Oxygen Uptake Add Prognostic Value in Aortic Stenosis”

Circulation

Circulation, Volume 150, Issue 16 , Page e276-e277, October 15, 2024.

Article 45
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Long-term transcranial ultrasound stimulation regulates neuroinflammation to ameliorate post-myocardial infarction cardiac arrhythmia and remodeling

HeartRhythm

Sympathetic overactivation and neuroinflammation in the paraventricular nucleus (PVN) are crucial factors in post-myocardial infarction (MI) cardiac remodeling and ventricular arrhythmias (VAs). Prior study has indicated that low-intensity focused ultrasound stimulation could attenuate sympathetic neuroinflammation within the PVN to prevent the occurrence of VAs in acute MI model.

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Pathogenesis of Atherothrombotic Events: From Lumen to Lesion and Beyond

Circulation

Circulation, Volume 150, Issue 16 , Page 1217-1219, October 15, 2024.

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The predictive role of the TAPSE/sPAP ratio for cardiovascular events and mortality in systemic sclerosis with pulmonary hypertension

Frontiers in Cardiovascular Medicine

IntroductionReduced TAPSE/sPAP ratio has recently emerged as a predictive parameter risk factor for PH, however its role in SSc has been poorly investigated. The aim of the study was to investigate the prognostic value of the TAPSE/sPAP ratio for the prediction of mortality and cardiovascular events in patients with SSc complicated by PH. A comparison between SSc patients with PAH (SSc-PAH) and those with PH and significant ILD (SSc-PH) was also carried out.Materials and methodsA retrospective s

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Patients With Advanced Heart Failure and Atrial Fibrillation Deserve an Attempt at Catheter Ablation as First-Line Therapy

Circulation

Circulation, Volume 150, Issue 16 , Page 1220-1222, October 15, 2024.

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Imminent risk of LVEF decline in asymptomatic patients with primary mitral regurgitation

Frontiers in Cardiovascular Medicine

Background2020 American College of Cardiology/American Heart Association (ACC/AHA) Guidelines state that the ideal time for mitral valve surgery in primary mitral regurgitation (PMR) is when the LV approaches but has not yet reached echocardiographic LV ejection fraction (EF)   40 mm. However, it is difficult to know the imminent risk of crossing this threshold when the surgical outcome is less optimal.ObjectiveUsing machine learning and statistical models, we have shown that cardiac magnetic re