Mon.Jun 24, 2024

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Generic Liraglutide (Victoza) Becomes First Generic GLP-1 Receptor Agonist

HCPLive

Teva Pharmaceuticals’ launch of an authorized generic of liraglutide injection 1.8 mg (Victoza) for type 2 diabetes makes it the first-ever generic GLP-1.

Diabetes 142
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Endotronix Receives FDA Premarket Approval of the Cordella PA Sensor System for the Treatment of Heart Failure

DAIC

milla1cf Mon, 06/24/2024 - 20:21 June 24, 2024 — Endotronix, Inc. , a privately held company dedicated to advancing the treatment of heart failure ( HF ) at the intersection of digital health and medtech, today announced Premarket Approval (PMA) from the U.S Food and Drug Administration ( FDA ) of the company's Cordella Pulmonary Artery (PA) Sensor System for the treatment of New York Heart Failure (NYHA) class III heart failure patients.

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Apremilast Effective, Safe Among Psoriasis Patients with Special Area Involvement

HCPLive

This analysis among Japanese patients highlights the potential of apremilast for psoriasis patients not responding to topical therapy who may have limited systemic treatment options.

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In Memoriam: Prolific Philanthropist Ann Lurie, Namesake of the Ann and Robert H Lurie Children’s Hospital of Chicago

DAIC

June 24, 2024 — Well-known Chicago and worldwide philanthropist Ann Lurie, namesake of the Ann and Robert H Lurie Children’s Hospital of Chicago, passed away on June 24 after succumbing to glioblastoma, an aggressive form of brain cancer. She was 79. Lurie’s philanthropic efforts were numerous and impactful, and provided vital support to the critical needs of multiple agencies around the world, including initiatives addressing hunger, healthcare deficiencies, animal welfare, arts enrichment and

Hospital 105
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King Charles' Sister Hospitalized; Mask Bill Vetoed; NFL Legend's Health Scare

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Princess Anne, the 73-year-old sister of King Charles III, sustained minor injuries and a concussion while on a walk; the cause is unclear, but her medical team.

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Smidt Heart Institute Experts Selected to Join JACC Editorial Team

DAIC

Aakriti Gupta, MD. Photo by Cedars-Sinai milla1cf Mon, 06/24/2024 - 20:17 June 24, 2024 — Aakriti Gupta, MD , and Michelle Kittleson, MD, PhD , cardiologists in the Smidt Heart Institute at Cedars-Sinai , have been selected to join the senior editorial team of the Journal of the American College of Cardiology (JACC), effective July 1. Gupta, an interventional and structural cardiologist, is one of the journal’s new executive associate editors.

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Major Heart Events Down With Metabolic Surgery for Apnea Patients With Obesity

Med Page Today

(MedPage Today) -- Metabolic surgery became the first therapy associated with a reduction in incident cardiovascular disease and death among patients with obesity and obstructive sleep apnea (OSA), based on a retrospective cohort study. Such patients.

Obesity 81

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First Issue of JACC Debuts Under Harlan M. Krumholz

American College of Cardiology

The first issue of JACC under new Editor-in-Chief Harlan M. Krumholz, MD, SM, FACC, published today, ushering in a new era of one of the world's leading scholarly journals.

Article 68
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Hand Eczema Significantly Reduces Quality of Life

HCPLive

A meta-analysis shows hand eczema has a moderate-to-severe impact on quality of life and anxiety.

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STEP-HFpEF: Body Weight Reduction With Semaglutide Greater in Women Than Men With Obesity-Related HFpEF

American College of Cardiology

Semaglutide reduces body weight to a greater extent in women with obesity-related heart failure with preserved ejection fraction (HFpEF) than in men, and improved Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) to the same extent in both women and men, according to results from a prespecified secondary analysis of pooled data from the STEP-HFpEF program presented at the American Diabetes Association’s 2024 Scientific Sessions and simultaneously published in JACC.

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FDA-Approved Red-Light LED Lamp Released for Patients with Actinic Keratosis

HCPLive

The announcement follows the release of the RhodoLED XL red light-emitting lamp, to be used in combination with aminolevulinic acid hydrochloride topical gel, 10% for actinic keratoses

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Addressing Global Burden of CVD in Women: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review addressing the global burden of cardiovascular disease (CVD) in women.

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Diabetes Dialogue: New Early-Stage T1D Monitoring Guidance, with Anastasia Albanese-O'Neill, PhD, APRN

HCPLive

Anastasia Albanese-O'Neill, PhD, APRN, joins Diabetes Dialogue to discuss newly released consensus guidance on monitoring of early-stage type 1 diabetes spearheaded by Breakthrough T1D.

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Standardized protocols help hospitals treat strokes faster

Science Daily - Stroke

Research illustrates that American Heart Association and American Stroke Association guidelines are effective at speeding up hospitals' response times for stroke treatment and can be mastered even by members of 'ad hoc' medical teams that assemble rapidly on the fly.

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ATTEMPT: Dapagliflozin Improves Renal Function, Glycemic Control in Children with Type 1 Diabetes

HCPLive

Findings highlight the potential utility of low-dose SGLT2 inhibitors for optimizing diabetes control and managing renal complications in pediatric patients with type 1 diabetes.

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PCSK9 inhibition: from effectiveness to cost-effectiveness

Frontiers in Cardiovascular Medicine

Dyslipidaemia is a complex disorder characterised by abnormal lipid levels in the blood, including cholesterol and triglycerides, and plays an important role in the development of atherosclerotic cardiovascular disease. Most risk factors for cardiovascular disease are modifiable, and dyslipidaemia is a key factor among them. It can result from a combination of genetic and environmental factors.

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Study Reveals Romosozumab, Denosumab Effectively Treats RA Complicated with Osteoporosis

HCPLive

Treatment with romosozumab or denosumab demonstrated comparable results among patients with either primary osteoporosis or those with rheumatoid arthritis complicated with osteoporosis over a 24-month period.

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RCES Scope of Practice

Alliance of Cardiovascular Professionals

RCES-Scope-of-Practice-ACVP-2017 Available for download! The Electrophysiology Laboratory (EPL) is one of the most unique medical environments in existence today. The goal of the electrophysiology lab is to perform diagnostic studies to obtain sufficient electrocardiographic and radiologic data regarding bradyarrhythmias, or tachyarrythmias, and then to perform interventional procedures while maintaining maximal patient safety and comfort.

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Dazodalibep Significantly Improves Disease Activity in Rheumatoid Arthritis

HCPLive

CD40L blockade with dazodalibep benefited disease activity scores, including tender and swollen joints, in patients with moderate-to-severe active RA.

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Cardiometabolic Health Congress (CMHC) will present the results of a webcast series designed to help practitioners improve patient care

Cardiometabolic Health Congress

As a leader in the field of research-based cardiometabolic health education, CMHC is proud to present its CME education outcomes study at ADA (American Diabetes Association) 2024 Scientific Sessions, which offers its education-focused agenda to a wide number of healthcare practitioners from all areas of the U.S. Boca Raton, FL, June 24, 2024 (GLOBE NEWSWIRE) — The ADA 2024 Scientific Sessions center on the latest cutting-edge advances in diabetes research, prevention, and care.

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Early Remission with Targeted Therapies Linked to Better Health Outcomes in Rheumatoid Arthritis

HCPLive

Patients who achieved early remission with upadacitinib or adalimumab following an inadequate response to methotrexate had less pain/fatigue and better physical quality of life.

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Left Ventricular Remodeling in Patients with Low Flow Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

The American Journal of Cardiology

Publication date: Available online 24 June 2024 Source: The American Journal of Cardiology Author(s): Carlo Mannina, Lakshay Chopra, Joseph Maenza, Francesca R Prandi, Edgar Argulian, Michael Hadley, Jonathan Halperin, Samin K Sharma, Annapoorna Kini, Stamatios Lerakis

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CGM Linked to HbA1c Improvements in Patients with Type 2 Diabetes, Regardless of Insulin Use

HCPLive

Study results highlight the impact of continuous glucose monitoring on glucose control and HbA1c improvements in patients with type 2 diabetes, regardless of treatment regimen.

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Potential perioperative cardiovascular outcomes in cannabis/cannabinoid users. A call for caution

Frontiers in Cardiovascular Medicine

BackgroundCannabis is one of the most widely used psychoactive substances. Its components act through several pathways, producing a myriad of side effects, of which cardiovascular events are the most life-threatening. However, only a limited number of studies address cannabis's perioperative impact on patients during noncardiac surgery.MethodsStudies were identified by searching the PubMed, Medline, EMBASE, and Google Scholar databases using relevant keyword combinations pertinent to the topic.R

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CATALYST Proves Hypercortisolism More Common than Previously Known in Type 2 Diabetes

HCPLive

The CATALYST trial sheds light on the true prevalence of hypercortisolism among difficult-to-control type 2 diabetes, with data at ADA 2024 shedding light on adrenal abnormalities and presence among subgroups.

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Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity

American College of Cardiology

The goal of the SURMOUNT-OSA trial was to determine the effect of tirzepatide, both alone and in the setting of positive airway pressure (PAP) therapy, on obstructive sleep apnea (OSA) burden in patients with obesity.

Obesity 56
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Vutrisiran Reduces Mortality, CV Events in ATTR-CM in Phase 3 Trial

HCPLive

Vutrisiran achieved statistically significant reductions in primary and all secondary endpoints for patients with ATTR-CM in the HELIOS-B trial.

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What Is the Impact of Elevated Gradients Post-TAVI For Degenerated SAVR Bioprostheses?

American College of Cardiology

Greater adverse events were associated with both low and high postprocedural aortic valve mean gradient extremes following transcatheter aortic valve implantation (TAVI) for degenerated surgical aortic valve replacement (SAVR) bioprostheses, indicating a complex and nonlinear relationship between gradients and clinical outcomes, according to a recent study published in Circulation: Cardiovascular Interventions.

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Stopping Lung Cancer Before It Starts with Steven Dubinett, MD, and Avrum Spira, MD

HCPLive

Dubinett and Spira rejoin Lungcast for an update on their team's research into lung cancer interception.

Cancer 64
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The Potential of AI in Cardiovascular Care Focus of Review

American College of Cardiology

Artificial intelligence (AI) has tremendous potential to transform cardiovascular care in several key areas, from discovery to practice, according to a JACC State-of-the-Art Review published June 24.

Article 49
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Adalimumab Biosimilar MSB11022 Demonstrates Comparable Safety, Efficacy in RA

HCPLive

At 8 months follow-up, 86.0% of patients with rheumatoid arthritis were in remission and 94.2% exhibited low disease activity.

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Importance of Extra-Cardiac Vagal Stimulation during Catheter Ablation for Vagal Atrial Fibrillation: What is the Hidden Trigger?

HeartRhythm

Vagal atrial fibrillation (AF) occurs in relatively young people without any organic heart disease, and its onset is caused by changes in autonomic nervous system tone, mainly parasympathetic, such as after eating or drinking alcohol. Clinical results demonstrate that pulmonary vein isolation (PVI) remains the cornerstone of AF ablation in these patients, but additional ablation of the ganglionated plexi (GP) has been proposed as a complementary strategy.

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FLOW Analysis Sheds Light on Effects of Combination Therapy with GLP-1 RA and SGLT2 Inhibitor

HCPLive

Data on outcomes stratified according to baseline use of SGLT2 inhibitors from the FLOW trial were presented at ADA 2024.

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Cigarettes vs. Varenicline for Smoking Cessation in Adults

American College of Cardiology

Are nicotine-containing electronic cigarettes (ECs) effective compared to varenicline for smoking cessation?

Article 60
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Racial Prevalence Trends of Arthritis Among US Adults: 2011 – 2018 Analysis

HCPLive

A national survey provides insight into the prevalence of arthritis based on race in the US from 2011 – 2018.

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Oxytocin discontinuation or Continuing in the Active Phase of Induced Labor: Maternal and Fetal Outcomes

BMH Medical Journal

Oxytocin, the most commonly used drug to induce labor, may cause adverse effects due to uterine hyperstimulation. The aim of this study is to compare the maternal and fetal outcomes of discontinued or continued oxytocin during the active phase of labor induction. This study was conducted on 70 pregnant women referred to Baath Mission Hospital in Sanandaj, Iran.

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Empagliflozin: primum inter pares among sodium-glucose cotransporter-2 inhibitors?

Journal of Cardiovascular Pharmacology

Sodium/glucose cotransporter 2 (SGLT2) inhibitors are a novel class of anti-diabetic medications which have proved capable of providing breakthrough cardiovascular benefits in a variety of clinical scenarios, including patients with heart failure or obesity, irrespective of diabetic status. Several SGLT2 inhibitors are available, but the most prominent ones are canagliflozin, dapagliflozin, and empagliflozin.