Mon.Dec 04, 2023

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Pharmacists Can Spur Switch to Recommended Drugs for Diabetes Patients With CVD

Med Page Today

(MedPage Today) -- ANAHEIM, Calif. -- A pharmacist-led intervention using notes in the electronic health record (EHR) proved effective for convincing primary care providers to switch veterans with diabetes and cardiovascular disease (CVD) to.

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Endovascular catheter opens blocked arteries deep within lungs

Science Daily - Heart Disease

A new endovascular catheter, recently approved by the U.S. Food and Drug Administration (FDA), is paving the way to more effective and safe treatment for acute pulmonary embolism. Already shown to be effective for reducing blockages in lung arteries, new research shows that this catheter also reduces blockages in the smaller segmental pulmonary artery branches.

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High Blood Pressure in Babies Linked to Adult Atherosclerosis

Med Page Today

(MedPage Today) -- The link between childhood blood pressure (BP) and adult atherosclerosis appeared stable going all the way back to infancy, suggesting that efforts to prevent arterial thickening may be beneficial starting at the earliest life.

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Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies

Circulation

Circulation, Ahead of Print. BACKGROUND:It is unknown whether dietary intake of polyunsaturated fatty acids (PUFA) modifies the cardiovascular disease (CVD) risk associated with a family history of CVD. We assessed interactions between biomarkers of low PUFA intake and a family history in relation to long-term CVD risk in a large consortium.METHODS:Blood and tissue PUFA data from 40 885 CVD-free adults were assessed.

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Cardiac Abnormalities in Hispanic/Latina Women With Prior De Novo Hypertensive Disorders of Pregnancy

Hypertension Journal

Hypertension, Ahead of Print. Background:Hypertensive disorders of pregnancy (HDP) are associated with long-term maternal risks for cardiovascular disease for reasons that remain incompletely understood.Methods:The HCHS/SOL (Hispanic Community Health Study/Study of Latinos), a multi-center community-based cohort of Hispanic/Latino adults recruited 2008 to 2011, was used to evaluate the associations of history of de novo HDP (gestational hypertension, preeclampsia, eclampsia) with echocardiograph

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Update on Cardiovascular Implantable Electronic Device Infections and Their Prevention, Diagnosis, and Management: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The American Heart Association sponsored the first iteration of a scientific statement that addressed all aspects of cardiovascular implantable electronic device infection in 2010. Major advances in the prevention, diagnosis, and management of these infections have occurred since then, necessitating a scientific statement update.

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Decades after blood pressure-related pregnancy complications, women can have changes in heart structure and function

Science Daily - Heart Disease

Hispanic/Latina women with a history of hypertensive disorders of pregnancy (HDP) -- conditions marked by high blood pressure during pregnancy -- are more likely to have abnormalities in their heart structure and function decades later when compared with women without a history of HDP, according to a new study. The findings also suggest that while having high blood pressure later in life can contribute to these abnormalities, HDP play the greater role, significantly raising a woman's risk of dev

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The case for eliminating racial and ethnic cardiovascular disparities in the USA

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 05 December 2023; doi:10.1038/s41569-023-00971-2 Racial and ethnic disparities in cardiovascular health in the USA result in a persistent mortality gap between white and Black individuals, increase health-care costs and compromise an egalitarian society. Solutions to racial inequities require risk factor control and the implementation of evidence-based medicine and anti-racism policies.

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Navigating the Dynamic Terrain of Mitral Valve Interventions: A Journey of Innovation and Expertise

ADN Center of Excellence

The realm of mitral valve disease management is witnessing an unprecedented surge of advancements. Physicians understanding of disease pathology, fortified by the integration of state-of-the-art imaging technologies, has propelled them toward a new era of precision diagnosis and sophisticated treatment modalities. The Evolution of Treatment Modalities Historically, surgical repair has stood as the cornerstone in addressing primary mitral regurgitation.

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Base editing therapy corrects long QT syndrome in mice

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 05 December 2023; doi:10.1038/s41569-023-00977-w Gene therapy involving adenine base editing can correct a pathogenic variant in the Scn5a gene and alleviate arrhythmia phenotypes in a mouse model of long QT syndrome type 3.

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The clinical and economic impact of extended battery longevity of a substernal extravascular implantable cardioverter defibrillator

Journal of Cardiovascular Electrophysiology

The clinical and economic impact of extended battery longevity of The EV ICD compared to the S-ICD. Abstract Introduction The extravascular implantable cardioverter defibrillator (EV ICD) has extended projected battery longevity compared to the subcutaneous implantable cardioverter defibrillator (S-ICD). This study used modeling to characterize the need for generator changes, long-term complications, and overall costs for both the EV ICD and S-ICD in healthcare systems of various countries.

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Application and Validation of Phenotype-Enhanced Variant Classification in East Asian Patients with Catecholaminergic Polymorphic Ventricular Tachycardia

HeartRhythm

Catecholaminergic polymorphic ventricular tachycardia (CPVT) has been identified as a notable cause of sudden cardiac death in children and young adults.1 Mutation of ryanodine receptor 2 (RYR2) is observed in the majority of CPVT patients and is inherited through an autosomal dominant pattern.2 Genetic tests can help clinicians diagnose CPVT and identify potentially at-risk individuals so that medication can be prescribed before the onset of lethal arrhythmias.1 The American College of Medical

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Impact of GLA Variant Classification on the Estimated Prevalence of Fabry Disease: A Systematic Review and Meta-Analysis of Screening Studies

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:The diagnosis of Fabry disease (FD) has relevant implications related to the management. Thus, a clear assignment ofGLAvariant pathogenicity is crucial. This systematic review and meta-analysis aimed to investigate the prevalence of FD in high-risk populations and newborns and evaluate the impact of differentGLAvariant classifications on the estimated prevalence of FD.METHODS:We searched the EMBASE and PubMed databases on Fe

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New York hospital launches open-heart surgery program

Becker's Hospital Review - Cardiology

Middletown, New York-based Garnet Health Medical Center recently launched its open-heart surgery program, Mid Hudson News reported Dec. 4.

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Author Correction: Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 05 December 2023; doi:10.

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Mount Sinai taps director of pulmonary hypertension

Becker's Hospital Review - Cardiology

Raymond Benza, MD, FACC, has been named director of pulmonary hypertension at the Mount Sinai Health System.

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Associations Between Genetic Variation in the Targets of Low-Density Lipoprotein–Lowering Drugs and Rheumatoid Arthritis

Circulation: Genomic and Precision Medicine

Circulation: Genomic and Precision Medicine, Ahead of Print.

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Hemodynamic Comparison of Resilia and Sapien 3/Ultra Transcatheter Heart Valves in Transcatheter Aortic Valve Replacement

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print.

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Percutaneous Debulking of a Tricuspid Valve Papillary Fibroelastoma: A Rare Presentation and Management Approach

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Ahead of Print.

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Changing Patterns of Stroke and Subtypes Attributable to High Systolic Blood Pressure in China From 1990 to 2019

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:It is unknown whether high systolic blood pressure had a similar effect on the disease burden of stroke subtypes. The aim of our study is to compare the long-term trends of stroke subtypes and sex groups attributable to high systolic blood pressure in China from 1990 to 2019.METHODS:Data about the age-standardized mortality rate and the age-standardized disability-adjusted life-year rate of stroke subtypes attributable to high systolic blood pressure in China w

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Patient?reported quality of life and acceptance of the extravascular implantable cardioverter?defibrillator: Results from pivotal study

Journal of Cardiovascular Electrophysiology

Abstract Introduction The pivotal study of the extravascular implantable cardioverter-defibrillator (EV ICD) recently demonstrated primary efficacy and safety endpoints comparable to previous ICD systems. Patient experience with this novel device has not been reported. The current study examined the standardized patient-reported outcome (PRO) metrics of quality of life (QOL) and patient acceptance of the device.