Mon.Aug 19, 2024

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Ep 197 Acute Heart Failure Risk Stratification and Disposition

ECG Cases

We over-admit low risk acute heart failure patients and under-admit high risk heart failure patients. In this podcast we discuss the diagnostic accuracy of various clinical features, lab tests and imaging modalities for acute heart failure, the 3 validated risk stratification tools and a simple approach to PoCUS for the diagnosis and prognostication of acute heart failure in the ED to improve our diagnostic accuracy and disposition decisions for patients with acute heart failure.

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Heart Defects in Kids Linked to Dads' Hepatitis B History Too

Med Page Today

(MedPage Today) -- A child's risk of congenital heart disease (CHD) may be related to a past hepatitis B virus (HBV) infection in either parent, according to a retrospective cohort study. Paternal preconception HBV infection was linked to significantly.

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Benzodiazepine linked to increased cardiovascular disease risk: Study

Becker's Hospital Review - Cardiology

Benzodiazepine class insomnia drugs were associated with an increased risk of cardiovascular disease, according to a study published Aug. 7 in the European Journal of Preventive Cardiology.

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Here's How Compounders Make Popular Weight-Loss Drugs

Med Page Today

(MedPage Today) -- This story is part of a series called "Ozempic: Weighing the Risks and Benefits." It was produced in part through a grant from the NIHCM Foundation. Shortages of popular new weight-loss drugs have driven a compounding boom that.

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Expanding a child's heart implant with light

Science Daily - Heart Disease

Children born with certain heart defects undergo a series of invasive surgeries early in life. The first surgery includes implantation of a shunt to improve blood flow. However, as children grow, the shunt must be replaced to accommodate their changing bodies. Now, researchers report designing a shunt that expands when activated by light. This device could reduce the number of open-chest surgeries these children receive.

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Improving access to heart-failure screening with a low-cost saliva test

Medical Xpress - Cardiology

Heart failure is a leading cause of death worldwide and is especially fatal for people who don't have access to medical facilities. So, a team of researchers aims to bring heart failure screening from the lab to the home. Their point-of-care electrochemical biosensor prototype, which resembles a see-through lateral flow test for COVID-19, can measure levels of two biomarkers for heart failure in as little as 15 minutes from just a drop of saliva.

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Nurses play key role in addressing mental well-being for people after a stroke

American Heart News - Stroke News

Statement Highlights: The latest research indicates that 16% to 85% of people recovering from a stroke experience at least one psychosocial symptom, including depression, anxiety, stress, fatigue and/or decreased quality of life. Critical nursing.

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Nurses play key role in addressing mental well-being for people after a stroke

Science Daily - Heart Disease

The latest research indicates that 16% to 85% of people recovering from a stroke experience at least one psychosocial symptom, including depression, anxiety, stress, fatigue and/or decreased quality of life. Critical nursing interventions, such as regular mental health screenings, education, symptom management and follow-up care, are key to reducing the negative effects on a patient's mental well-being after a stroke, yet only a small proportion of patients receive treatment.

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Researchers Hit the Road to Learn Why CVD and COPD Are Rampant in the Rural South

Med Page Today

(MedPage Today) -- Darrell Dixon's father was just 25 when he had a major heart attack in the rural Mississippi Delta. By his early 40s, a series of additional attacks had left his heart muscle too weak to pump enough blood to his body. He died.

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Study finds constipation is a significant risk factor for major cardiac events

Medical Xpress - Cardiology

An international study led by Monash University researchers has found a surprising connection between constipation and an increased risk of major adverse cardiac events (MACE), including heart attacks, strokes and heart failure.

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Diabetes Dialogue: First 10 Prices Announced from CMS Price Negotiations

HCPLive

In this episode, hosts react to the announced CMS list prices for the first 10 drugs chosen for negotiation as part of the Inflation Reduction Act.

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Improving access to heart-failure screening with saliva

Science Daily - Heart Disease

Heart failure is a leading cause of death worldwide and is especially deadly for people who don't have access to medical facilities. A team of researchers aims to bring heart failure screening from the lab to the home with a point-of-care electrochemical biosensor prototype that measures levels of two biomarkers for heart failure in as little as 15 minutes from just a drop of saliva.

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Analysis: 31 Inflammatory Proteins Impacted by Atopic Dermatitis

HCPLive

Identified proteins impacted by the presence of atopic dermatitis may provide clinicians a better understanding of how to treat it.

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Platelets under control: Protecting the heart and brain more effectively after an infarction

Medical Xpress - Cardiology

An unhealthy lifestyle, diseases or injuries, genetic predisposition, and increased coagulation tendency can promote the formation of thrombi in blood vessels. These clots obstruct the flow of blood to vital organs, which may lead to life-threatening infarction. Therefore, preventing and treating thrombosis is crucial to avoid severe complications.

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Talking to Patients about Atopic Dermatitis Treatment Response

HCPLive

Lindsay S. Ackerman, MD, FAAD, provides clinical insights on best practices for evaluating treatment response in patients with atopic dermatitis.

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How do you mend a damaged heart? Researchers have solid leads

Medical Xpress - Cardiology

UVA Health scientists seeking drugs that can trigger the regeneration of heart tissue after a heart attack say their efforts show promise and may lead to future treatment options.

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Poor Sleep, Renal Function Linked to Risk of Developing New-Onset MASLD

HCPLive

Participants with greater poor sleep and renal function biomarker scores had a 5.45-fold greater risk of developing severe MASLD.

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Nursing’s Role in Psychosocial Health Management After a Stroke Event: A Scientific Statement From the American Heart Association

Stroke Journal

Stroke, Ahead of Print. INTRODUCTION:Stroke can have profound psychosocial health implications. These constructs are often overlooked and undertreated yet can be as devastating as the physical, functional, and cognitive consequences after stroke.AIM:This scientific statement aims to evaluate 5 important aspects of psychosocial health (depression, stress, anxiety, fatigue, and quality of life) after a stroke to provide a framework for related nursing care across the poststroke continuum.METHODS:A

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Naim Alkhouri, MD: Benefit of Agile Scores for Noninvasive Fibrosis, Cirrhosis Testing

HCPLive

Alkhouri describes how Agile 3 + and Agile 4 scoring may help address issues with low positive predictive value seen with other noninvasive tests for MASLD fibrosis and cirrhosis.

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Prognostic value of cardiopulmonary exercise test in children with congenital heart defects

Open Heart

Background Cardiopulmonary exercise testing (CPET) has an important prognostic value in adults with different congenital heart defects (CHDs) and is a useful tool for risk stratification and clinical decision-making. In this retrospective study, we studied the prognostic value of CPET in paediatric patients with CHD. Methods 411 CPET performed by paediatric patients with different CHDs were evaluated in this retrospective study.

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Serum Uric Acid May Be Biomarker for Bipolar Affective Disorder

HCPLive

Uric acid levels, commonly used to indicate gout, are closely associated with bipolar-affected mania.

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Clinical relevance of aortic conduit and reservoir function

Open Heart

Background Aortic conduit and reservoir functions can be directly measured by four-dimensional flow (4D flow) cardiovascular magnetic resonance (CMR). Methods Twenty healthy controls (10 young and 10 age-gender-matched old controls) and 20 patients with heart failure with preserved ejection fraction (HFpEF) were recruited. All had 4D flow CMR. Flow was quantified at the ascending and descending aorta levels.

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Positioning PDS Within the Therapeutic Landscape

HCPLive

Dr. Dennis Marcus discusses how the PDS with ranibizumab fits into the treatment landscape and explores other sustained delivery mechanisms currently in development for neovascular AMD.

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AORTA Gene Score for Ascending Aortic Dilation

American College of Cardiology

Does incorporating polygenic risk into a clinical model improve estimation of ascending aortic diameter and the ascertainment of aneurysm as well as thoracic aortic dissection beyond clinical factors alone?

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Gout Remission Less Likely With Higher DECT Monosodium Urate

HCPLive

Another recent study found that the risk of joint damage and gout flares were most important to patients when considering ULT discontinuation.

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Colorado State researchers create at-home heart failure screening test

Becker's Hospital Review - Cardiology

"Discover the latest innovation in heart failure screening with an at-home testing device created by Colorado State University.

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HbA1c Highly Predicts NAFLD Disease Severity

HCPLive

A new analysis suggests HbA1c may be more informative to fatty liver disease severity than BMI, and should be included in screenings.

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Retrospective study explores mitral valve surgery outcomes in atrial functional mitral regurgitation

Medical Xpress - Cardiology

Mitral regurgitation (MR) is a serious heart condition that often requires corrective surgery. It is characterized by the backflow or "regurgitation" of blood from the heart's left ventricle into the left atrium.

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Patient’s Goals and Atopic Dermatitis Treatment Selection

HCPLive

Lindsay S. Ackerman, MD, FAAD, and Jonathan Silverberg, MD, PhD, MPH, discuss how patient goals inform treatment decisions for patients with atopic dermatitis.

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Nurses play key role in addressing mental well-being for people after a stroke

Medical Xpress - Cardiology

Nurses play a key role in helping patients manage emotional and social health challenges, or psychosocial health, after a stroke, and improved screening and assessment for psychosocial needs are essential to provide optimal patient care.

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Treprostinil Inhalation Powder (Yutrepia) Receives Tentative Approval for PAH and PH-ILD

HCPLive

On August 19, 2024, Liquidia Corporation announced the FDA's tentative approval of treprostinil inhalation powder for adults with PAH and PH-ILD.

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Management of Cardiac Sarcoidosis: Key Points

American College of Cardiology

The following are key points to remember from a clinical consensus statement on the management of cardiac sarcoidosis (CS) from the Heart Failure Association, the European Association of Cardiovascular Imaging, the European Society of Cardiology (ESC) Working Group on Myocardial & Pericardial Diseases, and the European Heart Rhythm Association of the ESC.

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Gil Yosipovitch, MD: Next Steps Following FDA Approval of Nemolizumab for Prurigo Nodularis

HCPLive

Yosipovitch spoke in this interview about the clinical trials leading up to the FDA approval of his nemolizumab for patients with prurigo nodularis.

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Lipid Management in Peripheral Artery Disease: A Focus on Recent and Evolving Data

American College of Cardiology

Peripheral artery disease (PAD) is a prevalent and severe form of atherosclerotic vascular disease, affecting >230 million people worldwide. PAD reduces patients' walking capacity and increases the risk of major adverse limb events (MALE) such as acute limb ischemia (ALI), amputation, or peripheral revascularization.

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Tofacitinib Monotherapy Adherence Lower Than Combination Therapy, More Research Needed

HCPLive

More patients also switched from combination therapy to monotherapy at any time in both analyzed database populations.

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Plant and Animal Fat Intake and Overall and CVD Mortality

American College of Cardiology

Is dietary plant or animal fat intake associated with overall and cardiovascular disease (CVD) mortality?

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Left Ventricular Remodeling in Aortic Stenosis and Systemic Hypertension: Phenotypical Look-Alikes or Distinct Siblings?

Circulation: Cardiovascular Imaging

Circulation: Cardiovascular Imaging, Volume 17, Issue 8 , Page e017266, August 1, 2024.