Thu.Jul 18, 2024

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HeartFlow Introduces Next Generation Interactive Plaque Analysis Platform to Assess Patient Risk in Suspected Coronary Artery Disease

DAIC

mtaschetta-millane Thu, 07/18/2024 - 10:00 July 18, 2024 — HeartFlow, Inc. , a leader in non-invasive artificial intelligence (AI) heart care solutions, introduced the next generation HeartFlow Plaque Analysis with an interactive experience. This upgraded platform is the only plaque analysis tool fully integrated with FFR CT (when FFR CT is performed), delivering impactful insights to enhance clinical decision-making and enabling personalized patient treatment plans.

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Functional control of myosin motors in the cardiac cycle

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 19 July 2024; doi:10.1038/s41569-024-01063-5 Contraction of the heart is driven by cyclical interactions between myosin and actin filaments driven by ATP hydrolysis. In this Review, Irving summarizes the basal cardiac cycle of the healthy human heart at the ventricular, cellular, sarcomeric, and molecular levels and the implications for the development of novel therapies for heart disease.

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Circle Cardiovascular Imaging Announces Leadership Transition

DAIC

Circle Cardiovascular Imaging has announced that Erkan Akyuz has been appointed Chief Executive Officer to succeed Circle co-founder and CEO Greg Ogrodnick. Image courtesy: Circle Cardiovascular christine.book Thu, 07/18/2024 - 13:32 July 18, 2024 — Circle Cardiovascular Imaging , a developer of artificial intelligence (AI)-driven cardiovascular imaging solutions, has announced that Erkan Akyuz has been appointed Chief Executive Officer, effective August 5, 2024.

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Boehringer Ingelheim, GoodRx Partner to Lower Costs of Adalimumab-adbm for Patients

HCPLive

Adalimumab-adbm is now available at a 92% discount from the reference drug list price through GoodRx.

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Elucid Commences International PRE-VUE CCT Registry Study

DAIC

mtaschetta-millane Thu, 07/18/2024 - 09:19 July 18, 2024 — Elucid , a pioneering AI medical technology company providing physicians with imaging analysis software based on ground truth histology to support diagnosis and treatment of cardiovascular disease, has initiated site recruitment for its Plaque as a Risk Factor for Evaluation of Vascular Events (PRE-VUE) CT Registry Study.

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Tennessee children's hospital, medical school tap pediatric surgery chief

Becker's Hospital Review - Cardiology

Le Bonheur Children's Hospital and the University of Tennessee Health Science Center, both based in Memphis, Tenn., have named Bret Mettler, MD, as the new chief of pediatric cardiac surgery and executive co-director of the Le Bonheur and UT Health Science Center Heart Institute.

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AliveCor's Kardia 12L ECG System Receives Category III CPT Codes

DAIC

mtaschetta-millane Thu, 07/18/2024 - 09:05 July 18, 2024 — AliveCor , a global leader in AI-powered cardiology , today announced that the American Medical Association (AMA) has granted new Category III Current Procedural Terminology (CPT) codes that are applicable to the company's Kardia 12L ECG System , which received FDA clearance in June 2024.

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UC Irvine to use $50M gift to boost cardiology research

Becker's Hospital Review - Cardiology

"UC Irvine receives $50 million gift from Joe Wen and family for cardiology advancements and research, renaming divisions and center in honor of Wen's parents a

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Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 19 July 2024; doi:10.1038/s41569-024-01047-5 During commercial spaceflight, individuals who might have underlying cardiovascular disease will be exposed to increased gravitational and acceleration (G) forces. In this Review, Morris and colleagues explore the use of computational models to simulate the effects of G forces on human cardiovascular pathophysiology to risk-stratify individuals and help to improve safety in commercial suborbital spaceflight

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ANX007 May Protect Visual Function, Structure in Geographic Atrophy

HCPLive

Phase 2 data from the ARCHER study shows a protective effect of ANX007 on visual acuity and anatomical measures in the central macula in patients with GA.

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Apixaban, Rivaroxaban, and Warfarin in Patients With Cirrhosis and AF

American College of Cardiology

What are the effectiveness and safety outcomes associated with apixaban versus rivaroxaban and versus warfarin in patients with cirrhosis and atrial fibrillation (AF)?

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Matthew Hoscheit, MD: Expanding the GERD Treatment Armamentarium with Vonoprazan

HCPLive

Vonoprazan (Voquenza), the first major innovation in GERD treatment in more than 30 years, is now FDA-approved for both erosive and non-erosive GERD.

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Leadless vs. Transvenous Pacemakers After TAVR

American College of Cardiology

What are the national trends in utilization of leadless pacemaker implantation following transcatheter aortic valve replacement (TAVR) and its performance compared with transvenous pacemakers?

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Katherine Talcott, MD: Baseline EZ Integrity Features Predict GA Progression

HCPLive

Katherine Talcott, MD describes a posthoc analysis of the GATHER trials showing how imaging biomarkers of photoreceptor structure predict GA growth.

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Meta-Analysis Comparing Drug-Coated Balloon Versus Plain Old Balloon Angioplasty for In-stent Restenosis of Coronaries

The American Journal of Cardiology

Publication date: Available online 18 July 2024 Source: The American Journal of Cardiology Author(s): Safia Shaikh, Mohammad Hamza, Prakash Upreti, Mohammad Akkawi, Kripa Rajak, Mobeen Zaka Haider, Nomesh Kumar, Mustafa Turkmani, Fadi Kathawa, Salman Abdul Basit, Yasemin Bahar, Sadaf Fakhra, Yasar Sattar, M Chadi Alraies

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Vonoprazan (Voquenza) Receives FDA Approval for Heartburn Associated with Non-Erosive GERD

HCPLive

Announced on July 18, 2024, the FDA approval for heartburn relief associated with non-erosive GERD is based on the phase 3 PHALCON-NERD-301 trial.

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A retrospective analysis of lymph node dissection in Siewert II adenocarcinoma of the esophagogastric junction

Journal of Cardiothoracic Surgery

Analyze the pattern of lymph node metastasis in Siewert II adenocarcinoma of the esophagogastric junction (AEG) and provide a basis for the principles of surgical access.

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Dilsher Dhoot, MD: Interim Results on OTX-TKI for NPDR in HELIOS

HCPLive

OTX-TKI remained generally well-tolerated in patients with moderately severe to severe NPDR across 48 weeks of the Phase 1 trial.

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Texas air crews train to transport patients with intra-aortic balloon pumps

Becker's Hospital Review - Cardiology

"Learn how AirLift Texas emergency air crews are now equipped to transport cardiac patients with intra-aortic balloon pumps, providing faster and safer access t

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Discussing New Findings on Ruxolitinib for Children with Eczema, with Linda Stein Gold, MD

HCPLive

In this Q&A interview, Stein Gold discusses new phase 3 findings regarding ruxolitinib cream 1.5% for patients 2 to 11 years old with atopic dermatitis.

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Highlights From the Proposed 2025 Hospital OPPS Rule

American College of Cardiology

The Centers for Medicare and Medicaid Services (CMS) released the proposed 2025 Hospital Outpatient Prospective Payment System (OPPS) and Ambulatory Surgical Center (ASC) Payment System rule on July 10. CMS proposes a 2.6% increase to OPPS payment rates that reflects a market basket update of 3.0% reduced by a productivity adjustment of 0.4%.

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HIV: Treating Patients with Viral Mutations

HCPLive

Sorana Segal-Maurer, MD, offers clinical insights on treating patients with HIV who have viral mutations, including M184V, highlighting guideline recommendations.

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Evaluation of success and complications scores for chronic total occlusion percutaneous coronary interventions: insights from the LATAM registry

The American Journal of Cardiology

Publication date: Available online 17 July 2024 Source: The American Journal of Cardiology Author(s): Pedro Piccaro de Oliveira, Anibal P. Abelin, Guilherme Pinheiro Machado, Evandro M. Filho, Gustavo N. Araujo, Leandro A. Côrtes, Lucio Padilla, Sebastian Pablo Peralta, Ricardo Santiago, João E.T. de Paula, Antonio Carlos Botelho, Mauro Echavarria-Pinto, Felix Damas de los Santos, Marcelo H.

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Cardiovascular Disease Rates is Greater in Younger Than Older Adults with OSA

HCPLive

Younger adults (aged 20 – 40 years) with OSA were 3 times more likely to experience any type of CVD event than those without OSA.

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One-Month DAPT Reduces Major Bleeding Compared with Longer Term Treatment without Excess Stent Thrombosis: a Systematic Review and Meta-analysis of Randomized Clinical Trials

The American Journal of Cardiology

Publication date: Available online 17 July 2024 Source: The American Journal of Cardiology Author(s): Gani Bajraktari, Ibadete Bytyçi, Genc Abdyli, Pranvera Ibrahimi, Artan Bajraktari, Rona Karahoda, Shpend Elezi, Michael Y.

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XTEND-Kids Trial Reinforces Safety, Efficacy of Efanesoctocog Alfa in Children

HCPLive

The XTEND-Kids phase 3 trial shows efanesoctocog alfa’s safety and efficacy in children with severe hemophilia A, reducing bleeds with once-weekly dosing.

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Clinical Outcomes of Metabolic Surgery on Diuretic Use in Patients with Heart Failure

The American Journal of Cardiology

Publication date: Available online 17 July 2024 Source: The American Journal of Cardiology Author(s): Michael Kachmar, Florina Corpodean, Courtney LaChute, Iryna Popiv, Michael Cook, Denise M Danos, Vance L Albaugh, Denzil L Moraes, WH Wilson Tang, Philip R Schauer

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Durability of Effect and Advice to Improve Quality of Life in Atopic Dermatitis

HCPLive

Shawn Kwatra, MD, discusses the durability of treatments for atopic dermatitis and provides advice for clinicians on improving patients’ quality of life.

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Advancements in Incident Heart Failure Risk Prediction & Screening Tools

The American Journal of Cardiology

Publication date: Available online 18 July 2024 Source: The American Journal of Cardiology Author(s): Daniel S. Matasic, Ralph Zeitoun, Gregg C. Fonarow, Alexander C. Razavi, Roger S.

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Safety Data of Oral JAK Inhibitors in Atopic Dermatitis

HCPLive

An academic dermatologist discusses the safety profiles of abrocitinib and upadacitinib and provides clinical insights on patient monitoring practices.

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Intensive BP Reduction for Preventing Major Adverse Cardiovascular Events

NEJM Journal Watch - Cardiology

A randomized trial showed benefits for patients with or without diabetes or prior stroke.

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Choosing Between Oral JAK Inhibitors in Atopic Dermatitis

HCPLive

Ruth Ann Vleugels, MD, MPH, MBA, provides insights on factors that inform JAK inhibitor treatment selection for patients with atopic dermatitis.

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From Risk to Resilience: improved outcomes after myocardial infarction in patients with Sjogren’s syndrome

Journal of Cardiovascular Pharmacology

An abstract is unavailable. This article is available as a PDF only.

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Impact of JAK Inhibitors on Itch and Quality of Life in Atopic Dermatitis

HCPLive

Shawn Kwatra, MD, provides an overview of oral JAK inhibitors for the treatment of atopic dermatitis, highlighting data from clinical trials.

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ECG Blog #439 — How Many Possibilities?

Ken Grauer, MD

How would YOU interpret the rhythm in Figure-1 — if you were sent this tracing without the benefit of any history? Figure-1: How would YOU interpret this rhythm? The "Quick" Answer: My initial thoughts on the rhythm in Figure-1 : The rhythm in Figure-1 is not completely regular. That said — the R-R interval for the first 5 beats looks regular. The R-R interval for the last few beats is shorter than this — but also regular.

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Candidates for Oral JAK Inhibitor Use in Atopic Dermatitis

HCPLive

An expert on atopic dermatitis identifies patients who are good candidates for JAK inhibitors, highlighting contraindications for treatment.

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Innovations in GERD: What Vonoprazan (Voquezna) May Offer Over PPIs, with Adelina Hung, MD

HCPLive

The novel potassium-competitive acid blocker now boasts 3 FDA approvals across erosive and non-erosive GERD, expanding the treatment armamentarium for patients and clinicians.