Thu.Aug 08, 2024

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ECG Blog #442 — And then the Patient Arrested.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that that this middle-aged woman noted chest tightness and nausea an hour earlier. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? — IF told that this patient arrested shortly after ECG #1 — Does this change your interpretation? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original EC G using PMcardio ).

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Hepatic Benefits of GLP-1 RAs Are Independent of Weight Loss in MASLD, Diabetes

HCPLive

Treatment with GLP-1 RAs led to improvements in weight loss, liver function tests, and liver fat in patients with diabetes and MASLD, with hepatic improvements independent of weight loss.

Diabetes 105
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Short, intense bursts of exercise more effective after stroke than steady, moderate exercise

Science Daily - Heart Disease

Significant improvements in aerobic fitness were noted after 12 weeks of high-intensity interval training sessions compared to traditional, moderate exercise sessions, according to a new study.

Exercise 107
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Opioid Pain Treatment Raises Dependence and Use Disorder Rates

HCPLive

A new study revealed patients with chronic pain treated with opioid analgesics had a greater prevalence of opioid dependence, opioid use disorder, and aberrant behavior.

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Creative Alliances in Cardiorenal Metabolic Management: A Game Changer (Part 1) 

Cardiometabolic Health Congress

Cardiometabolic risk encompasses a complex spectrum of interrelated conditions, including cardiovascular disease, type 2 diabetes, and metabolic syndrome. These interconnected diseases pose a significant global health threat, with cardiovascular diseases alone accounting for one-third of all deaths worldwide , according to the World Health Organization.

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Atopic Dermatitis Linked to Stress, Depression, Anxiety, Suicidal Ideation

HCPLive

Atopic dermatitis increases stress, depression, anxiety, and suicidal ideation, affecting patients' mental health, a recent study found.

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New Expert Consensus Decision Pathway Updates Guidance on HF Management, Treatment

American College of Cardiology

A newly released ACC Expert Consensus Decision Pathway (ECDP) focused on the clinical assessment, management and trajectory of patients hospitalized with heart failure (HF) includes revisions to the 2019 version of the document and harmonizes guidance in response to the ACC/AHA Heart Failure Guideline released in 2022.

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Optimal Medical Therapy and Outcomes in Chronic HFrEF

American College of Cardiology

What are the outcomes in patients with chronic heart failure and reduced ejection fraction (HFrEF) as determined by their optimal medical therapy (OMT) score?

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Targeting Disease Modification for Psoriasis and Psoriatic Arthritis

HCPLive

Medical experts engage in a discussion surrounding the treatment and management of patients diagnosed with psoriasis and psoriatic arthritis.

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Update to ACC/AHA HF Performance and Quality Measures: Key Points

American College of Cardiology

The following are key points to remember from the 2024 update to the 2020 American College of Cardiology/American Heart Association (ACC/AHA) clinical performance and quality measures for adults with heart failure (HF).

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Discussing the Global Prevalence of Seborrheic Dermatitis, with Raj Chovatiya, MD, PhD

HCPLive

In this interview, Chovatiya spoke with the editorial team about the global prevalence findings on patients with seborrheic dermatitis and their implications.

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Outcomes of AF Ablation Among Older Adults in the US

American College of Cardiology

What are the patient characteristics, population rates, and 30-day outcomes of pulmonary vein isolation (PVI) in a nationwide sample of US adults aged >65 years?

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Dupilumab Maintains Effectiveness in AD for Up to 5 Years, But 1 in 4 Still Discontinue Treatment

HCPLive

Study finds 70% of atopic dermatitis patients using dupilumab continued for up to 5 years, but 23.8% discontinued primarily due to adverse events or ineffectiveness.

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Time to assess more than prognosis: advancements and challenges in transcatheter tricuspid valve interventions

Frontiers in Cardiovascular Medicine

We provide an overview about the current landscape of transcatheter tricuspid valve interventions (TTVI) and summarize recent findings from trials including TRILUMINATE, TRILUMINATE Pivotal, bRIGHT, TRICLASP, TRISCEND, TRISCEND II, TRICUS, and Cardioband TR EFS. These studies have demonstrated the safety and efficacy of TTVI. Yet, they have failed to show a prognostic benefit over conservative treatment.

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UNITY: Nipocalimab Improves Survival in Early-Onset Severe HDFN

HCPLive

Nipocalimab led to a substantially higher percentage of live births at 32 weeks’ gestation or later without intrauterine transfusions than the historical benchmark.

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Transcriptomics integrated with metabolomics reveals partial molecular mechanisms of nutritional risk and neurodevelopment in children with congenital heart disease

Frontiers in Cardiovascular Medicine

PurposeTo explore molecular mechanisms affecting nutritional risk and neurodevelopment in children with congenital heart disease (CHD) by combining transcriptome and metabolome analysis.MethodsA total of 26 blood and serum samples from 3 groups of children with CHD low nutritional risk combined with normal neurodevelopment (group A), low nutritional risk combined with neurodevelopmental disorders (group B) and high nutritional risk combined with normal neurodevelopment (group C) were analyzed by

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Esketamine Safety Mechanisms and Bioavailability

HCPLive

Geoffrey Grammer, MD closes this series highlighting the administration options of esketamine, its safety profile, and the importance of monitoring patients using this treatment.

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Case Report: Electroanatomic mapping as an early diagnostic tool in arrhythmogenic cardiomyopathy

Frontiers in Cardiovascular Medicine

BackgroundAbnormal substrate on invasive electroanatomic mapping (EAM) correlates with areas of myocardial thinning and fibrofatty replacement in Arrhythmogenic Cardiomyopathy (ACM). However, EAM parameters are absent from all sets of diagnostic criteria for ACM.Case summaryA 41-year-old female with no significant family history was referred for evaluation of frequent premature ventricular complexes (PVCs).

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Evolving Goals in Rheumatoid Arthritis Treatment: Defining and Achieving Clinical Remission

HCPLive

A panel of medical experts discuss how clinical guidelines currently define clinical remission, as well as the clinical and economic benefits associated with clinical remission.

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Case Report: Extended cardiopulmonary resuscitation in sudden cardiac arrest after acute myocardial infarction

Frontiers in Cardiovascular Medicine

Out-of-hospital cardiac arrest (OHCA) mostly occurs in crowded public places outside hospitals, such as public sports facilities, airports, railway stations, subway stations, and shopping malls. The emergency department of Liaocheng People's Hospital in Shandong Province admitted one patient with OHCA in August 2021, who suddenly suffered a loss of consciousness and cardiac arrest during exercise after dinner.

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Impact and Costs of Treatment Resistant Depression

HCPLive

Harman Deol, MD begins this series presenting an overview of treatment resistant depression (TRD), highlighting its prevalence along with its impact on patients and the healthcare system.

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Clues for Smarter Rhythm Monitoring After Cardiac Surgery?

Med Page Today

(MedPage Today) -- Continuous rhythm monitoring after cardiac surgery held clues to help identify people prone to late postoperative atrial fibrillation (POAF) and any associated adverse events. In the RACE V prospective cohort study, over half.

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Treatment Options for TRD

HCPLive

William Sauve, MD shares the growing landscape of treatments for treatment resistant depression (TRD) and their mechanism of action, such as brain stimulation through electroconvulsive therapy or medication such as esketamine.

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$13M cardiac cath lab project underway at New York hospital

Becker's Hospital Review - Cardiology

Buffalo, N.Y. based-Catholic Health has started construction on a $13 million cardiac catheterization lab renovation at Mercy Hospital of Buffalo, according to an Aug. 7 report by NBC affiliate WGRZ.

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The Complete Guide to the Investing In You Educational Summit 2024

Cassling

The Investing In You Educational Summit is right around the corner. The full agenda has been unveiled, the state-of-the-art imaging systems you can experience firsthand are all set, and we at Cassling are ready to welcome you to Omaha to see what the future holds for the imaging field. As we get closer to the event on August 26 and 27, we’ve fielded questions from attendees and put together this helpful guide to understanding every aspect of the event.

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Study: Cardiology Trainees May Be Exposed to Unnecessary Radiation Risks

DAIC

tim.hodson Thu, 08/08/2024 - 10:19 Radiation from X-rays is an occupational hazard for many medical specialists, including cardiologists, vascular and orthopedic surgeons, urologists, some radiologists and gastroenterologists. Especially during the first trimester of pregnancy, radiation exposure for these providers can pose a threat to the fetus. To determine radiation risks to pregnant medical trainees, UCSF researchers conducted a study to determine how well radiation safety measures were en

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VALIANT: Pegcetacoplan Significantly Reduces Proteinuria in C3 Glomerulopathy, IC-MPGN

HCPLive

Positive topline results from the phase 3 VALIANT study show promise for pegcetacoplan in patients with C3 glomerulopathy and primary immune complex membranoproliferative glomerulonephritis.

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ACC/AHA Add Nine New Performance and Quality Measures to Updated 2024 Heart Failure Measure Set

American College of Cardiology

Three new performance measures and six new quality measures are included as part of updated "Clinical Performance and Quality Measures for Adults With Heart Failure" released by the ACC and the American Heart Association (AHA) in collaboration with the Heart Failure Society of America (HFSA) on Aug. 8.

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Esketamine for TRD: MOA, Application, and Adverse Events

HCPLive

Robert Zalewski-Zaragoza, MD expands on the option of esketamine for treatment resistant depression, highlighting the unique mechanism of action and application.

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ACE Inhibitor and Angiotensin Receptor Blocker use during Pregnancy: data from the ESC Registry Of Pregnancy And Cardiac disease (ROPAC)

The American Journal of Cardiology

Publication date: Available online 7 August 2024 Source: The American Journal of Cardiology Author(s): Johanna A. van der Zande, Karishma P. Ramlakhan, Katja Prokselj, Edison Muñoz-Ortiz, Amalia Baroutidou, Magdalena Lipczynska, Edit Nagy, Tobias Rutz, Arie Franx, Roger Hall, Mark R. Johnson, Jolien W.

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Obesity Indicators Linked to Gout Risk in Patients with Type 2 Diabetes

HCPLive

Levels of obesity indicators, including body mass index and waist circumference, were notably higher in patients with gout compared to those without gout.

Obesity 52
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RandomizEd comparison of PRogrESsion of atherosclerotic plaquEs aNd calcificaTion of coronary artery in Atrial Fibrillation patients treated with edoxaban versus warfarin (The REPRESENT-AF trial)

The American Journal of Cardiology

Publication date: Available online 8 August 2024 Source: The American Journal of Cardiology Author(s): Jinhee Ahn, Yoon Seong Lee, Whal Lee, BaRen Jeong, Eue-Keun Choi, Dong Geum Shin, Sang-Jin Han, Hong Euy Lim

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Intro and Welcomes

HCPLive

A panel of medical experts introduce themselves before diving into a discussion about remission achievement in rheumatoid arthritis.

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Stroke: Strong and Strengthening

Stroke Journal

Stroke, Ahead of Print.

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Etanercept Biosimilar Demonstrates Bioequivalence in Phase 3 Study

HCPLive

A total of 82.3% of patients in the biosimilars group and 90.9% in the reference drug group achieved an ACR20 response.

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Sex, Race, and Rural-Urban Disparities in VT Ablations

American College of Cardiology

Are there differences in patients hospitalized with ventricular tachycardia (VT) who received catheter ablations with potential disparities in access and utilization of VT ablation?

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Heavy Metal Exposure Linked to Increased Risk of Arthritis

HCPLive

Results showed particular heavy metals increased the risk of arthritis.

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