Dr. Smith's ECG Blog

NOVEMBER 25, 2024

Introductory Angiography Guide To find the guide later, go to the banner at the top of the blog: This blog is dedicated to improving understanding of ECGs in the context of emergency medicine. A substantial proportion of cases discussed include diagnostic angiography. Attaining expertise in angiography requires dedication and practice. What follows is an introduction to angiography -- a guide meant for people with no prior experience interpreting angiograms.

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Blog Document 73

Science Daily - Heart Disease

NOVEMBER 25, 2024

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.

Diabetes 68

Diabetes Obesity Outcomes 68

HCPLive

NOVEMBER 25, 2024

Emapalumab may improve outcomes in patients with MAS whose disease didn’t respond to steroid therapy and mitigate the need for more toxic therapies.

Outcomes 72

Outcomes 72

Cardiovascular Diabetology

NOVEMBER 25, 2024

Diabetic cardiomyopathy (DCM) is a severe cardiovascular complication of diabetes characterized by myocardial hypertrophy, fibrosis, and impaired cardiac function. Fibroblast growth factor 21 (FGF21) has emerg.

Cardiomyopathy 52

Cardiomyopathy Diabetes Cardiac Function 52

HCPLive

NOVEMBER 25, 2024

Panelists discuss the importance of screening and monitoring family members of individuals with IgA nephropathy, noting that up to 15% of cases are familial and outlining recommendations for the frequency of such assessments.

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Cardiovascular Diabetology

NOVEMBER 25, 2024

Type 1 diabetes increases the risk of coronary artery disease (CAD). High-throughput metabolomics may be utilized to identify metabolites associated with disease, thus, providing insight into disease pathophys.

Coronary Artery Disease 52

Coronary Artery Disease Diabetes Research 52

HCPLive

NOVEMBER 25, 2024

Panelists discuss how IgA nephropathy affects patients’ quality of life, addressing both the physical symptoms and the emotional challenges associated with the condition.

Quality of Life 59

Quality of Life 59

HCPLive

NOVEMBER 25, 2024

Hypovitaminosis D was more prevalent in patients with lupus nephritis compared to patients with systemic lupus erythematosus without kidney disease.

Kidney Disease 64

Kidney Disease 64

Dr. Paddy Barrett

NOVEMBER 25, 2024

The Heart Health Formula is available from today until Sunday, Dec 1st. You might have received an email saying today is the LAST day of availability, but it's not. It is the first day. Apologies for the earlier email. This was a scheduling error on our part. But if you want to pick up the Heart Health Formula for 30% off, you can do so from today until Sunday.

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HCPLive

NOVEMBER 25, 2024

These data, presented at ACR 2024, demonstrate that response was maintained at 2 years among those with psoriatic arthritis who responded to bimekizumab at Week 16.

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Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

Heat exposure could cause organ injuries leading to multi-organ failure. This case report describes a cardiopulmonary healthy 61-year-old woman who was admitted to our university hospital in an unconscious state after spending more than 30 min in an 80°C sauna. Initial radiological imaging revealed no pathological findings. Laboratory results revealed a rapidly progressing disseminated intravascular coagulation (“DIC”) and a clinically asymptomatic COVID-19 infection.

Hemorrhage 52

Hemorrhage COVID-19 Laboratory Strokes 52

HCPLive

NOVEMBER 25, 2024

This post-hoc analysis demonstrated an association between work productivity and stringent disease control criteria for those with psoriatic arthritis.

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Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

IntroductionCardiovascular diseases include myocardial infarction, a high mortality disease. Myocardial infarction patients are becoming younger, typically defined as patients under 45 years of age. This study analyzes the relevant papers on myocardial infarction in youth in the Web of Science Core Collection (WoSCC) between 1980 and 2023.MethodsIt uses bibliometric methods to systematically understand the current status and development trend of research in this field.

Myocardial Infarction 52

Myocardial Infarction Research Academic 52

DAIC

NOVEMBER 25, 2024

tim.hodson Mon, 11/25/2024 - 18:06 Nov. 22, 2024 — BridgeBio Pharma, Inc. recently announced that the U.S. Food and Drug Administration (FDA) approved Attruby (acoramidis), an orally-administered near-complete (≥90%) stabilizer of Transthyretin (TTR) for the treatment of adults with ATTR-CM to reduce cardiovascular death and cardiovascular-related hospitalization.

Quality of Life 52

Quality of Life Hospital Outcomes 52

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

BackgroundAtherosclerosis, a complex chronic vascular disorder with multifactorial etiology, stands as the primary culprit behind consequential cardiovascular events, imposing a substantial societal and economic burden. Nevertheless, our current understanding of its pathogenesis remains imprecise. In this investigation, our objective is to establish computational models elucidating molecular-level markers associated with atherosclerosis.

Atherosclerosis 52

Atherosclerosis Biomarkers Plaque Hypertension 52

Becker's Hospital Review - Cardiology

NOVEMBER 25, 2024

Ninety-five percent of CPR training manikins on the global market are flat-chested, possibly contributing to disproportionate survival outcomes for women after cardiac arrest, according to a study published Nov. 21 in Health Promotional International.

Cardiac Arrest 52

Cardiac Arrest Outcomes 52

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

Cardiovascular diseases (CVDs) encompass a range of disorders affecting the heart and blood vessels, such as coronary heart disease, cerebrovascular disease (e.g., stroke), peripheral arterial disease, congenital heart anomalies, deep vein thrombosis, and pulmonary embolism. CVDs are often referred to as the leading cause of mortality worldwide. Recent advancements in deep sequencing have unveiled a plethora of noncoding RNA transcripts, including circular RNAs (circRNAs), which play pivotal rol

Cardiovascular Disease 52

Cardiovascular Disease Peripheral Arterial Disease Cerebrovascular Disease Thrombosis 52

Becker's Hospital Review - Cardiology

NOVEMBER 25, 2024

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those, 97 hospitals were recognized for delivering superior clinical outcomes in cardiac care for heart bypass surgery, coronary interventional procedures, heart attack treatment, heart failure treatment and heart valve surgery.

Hospital 52

Hospital Heart Attack Heart attacks Heart Valves 52

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

Pathological transdifferentiation, where differentiated cells aberrantly transform into other cell types that exacerbate disease rather than promote healing, represents a novel and significant concept. This perspective discusses its role and potential targeting in cardiovascular diseases and chronic inflammation. Current therapies mainly focus on mitigating early inflammatory response through proinflammatory cytokines and pathways targeting, including corticosteroids, TNF-α inhibitors, IL-1β mon

Cardiovascular Disease 52

Cardiovascular Disease Biomarkers Research Outcomes 52

Med Page Today

NOVEMBER 25, 2024

(MedPage Today) -- Acoramidis (Attruby) gained FDA approval for treating wild-type or variant transthyretin (TTR) amyloidosis cardiomyopathy (ATTR-CM), BridgeBio Pharma announced. Offering patients near-complete TTR stabilization in an oral tablet.

Cardiomyopathy 52

Cardiomyopathy 52

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

BackgroundIt remains unclear whether the current recommended ablation index (AI) value is suitable for individualized catheter ablation. Prior research has established that the elimination of the negative component of the unipolar electrogram (UP-EGM) applications reflects the formation of transmural lesion during radiofrequency ablation. The aim of this study was to explore the relationship between AI values when UP-EGM turns positive during pulmonary vein isolation and recommended AI values.Me

Ablation 52

Ablation Pulmonary Atrial Fibrillation Research 52

Becker's Hospital Review - Cardiology

NOVEMBER 25, 2024

Memorial Hospital at Gulfport (Miss.) reported the highest Medicare payment of $38,459 for heart attack care between July 1, 2020, and June 30, 2023, according to CMS data published Oct. 30.

Heart Attack 52

Heart Attack Heart attacks Medicare Hospital 52

Cardiometabolic Health Congress

NOVEMBER 25, 2024

If you’re looking to revisit or explore the sessions from the 19th Annual Cardiometabolic Health Congress (CMHC), we’ve got good news—on-demand access is now available! Below, we answer the most common questions about CMHC On-Demand to help you make the most of this resource and stay updated on key developments in cardiometabolic health. If you attended the 19th Annual Cardiometabolic Health Congress (CMHC), please reach out to info@cardiometabolichealth.org and we will provide you with a compli

CME 52

CME Obesity Certification Education 52

Heart BMJ

NOVEMBER 25, 2024

Cardiac rehabilitation (CR) is a multidisciplinary supervised programme which typically consists of tailored exercise and education on lifestyle management and risk factor modification in cardiac patients. Participation in CR reduces morbidity and mortality, while improving quality of life following major cardiovascular events. Despite the benefits of CR, it is underutilised, generally in the 20%–30% range for eligible patients.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Quality of Life Risk Factors Exercise 52

Frontiers in Cardiovascular Medicine

NOVEMBER 25, 2024

BackgroundThe relationship between serial changes in physical activity and the risk of developing atrial fibrillation (AF) has been rarely studied.ObjectivesTo evaluate the association between changes in physical activity over time and the incidence of AF.MethodsA total of 11,828 participants without AF at baseline (visit 1: 1987–1989) from the ARIC Study were included.

Atrial Fibrillation 52

Atrial Fibrillation Outcomes Research 52

Heart BMJ

NOVEMBER 25, 2024

Background Participation in regular exercise activities is recommended for patients with chronic heart failure. However, less is known about the effect of exercise in patients with genetic dilated cardiomyopathy (DCM). We sought to examine the effect of vigorousintensity training on physical capacity in patients with DCM caused by truncating titin variants (TTNtv).

Exercise 52

Exercise Cardiomyopathy Outpatient Biomarkers 52

HCPLive

NOVEMBER 25, 2024

Panelists discuss how early detection of chronic kidney disease (CKD) in stages 2 and 3 can improve patient outcomes across various specialties, including nephrology, cardiology, and primary care.

Kidney Disease 52

Kidney Disease Outcomes 52

Heart BMJ

NOVEMBER 25, 2024

Background Rapid Access Chest Pain Clinics (RACPC) are widely used for the outpatient assessment of chest pain, but there appears to be limited high-quality evidence justifying this model of care. This study aimed to review the literature to determine the effectiveness of RACPCs. Methods A systematic review of studies evaluating the effectiveness of RACPCs was conducted to assess the quality of the evidence supporting this model.

Chest Pain 52

Chest Pain Outcomes Outpatient 52

HCPLive

NOVEMBER 25, 2024

Panelists discuss the high rates of missed chronic kidney disease (CKD) diagnoses despite testing and the consequences of diagnosing CKD in patients with type 2 diabetes without administering treatment, including insights on how frequently this occurs among cardiologists and primary care providers.

Kidney Disease 52

Kidney Disease Diabetes 52

Heart BMJ

NOVEMBER 25, 2024

Regular physical activity combined with structured exercise training has well described benefits for quality of life and mortality in a range of cardiovascular conditions. For individuals with underlying genetic cardiac myopathies there has been concern that exercise training could trigger a potentially fatal event. Thus, there has been caution with recommending exercise training broadly, especially with respect to vigorous intensity exercise and participation in competitive sports.

Exercise 52

Exercise Cardiomyopathy Quality of Life Congenital 52

HCPLive

NOVEMBER 25, 2024

Clinically meaningful increases in patient-reported outcomes were identified after 3 doses of SEL-212 and strengthened after 3 additional doses.

Outcomes 59

Outcomes 59

Heart BMJ

NOVEMBER 25, 2024

A set of keys to one’s first car is an unrivalled symbol of personal autonomy and liberation. The elation a teenager feels when getting the car keys for the first time (now more likely to be fobs, phones or fingerprints) is only equaled in intensity by the crushing defeat of being stripped of this privilege when, say, curfew is broken. For people with medical problems, relinquishing one’s driving privileges, in this case for reasons of health and safety, is a difficult, often content

Defibrillator 52

Defibrillator 52

HCPLive

NOVEMBER 25, 2024

Lowering serum urate level to less than 6 mg/dL was not linked to an elevated risk of severe or end-stage kidney disease progression in patients with gout.

Kidney Disease 52

Kidney Disease 52

Heart BMJ

NOVEMBER 25, 2024

10.1136/heartjnl-2024-324724corr1 Makkar N, Arasan S, Namboodiri N. Too fast, too furious. Heart 2024; 110: 1164-1196. This article has been corrected since it was first published. The correct answer, ‘B: Atrial pacing at a high set rate’ was missing and has now been added to the online version.

Article 52

Article 52

HCPLive

NOVEMBER 25, 2024

At ACR, HCPLive spoke with Erin Treemarcki on a survey that showed many rheumatologists do not use established enthesitis scoring measures for children.

Pediatrics 52

Pediatrics 52

Cardiovascular Diabetology

NOVEMBER 25, 2024

The burden of atrial fibrillation (AF) in the intensive care unit (ICU) remains heavy. Glycaemic control is important in the AF management.

Atrial Fibrillation 52

Atrial Fibrillation ICU Research 52

HCPLive

NOVEMBER 25, 2024

At ACR, HCPLive spoke with Ashima Makol, MD, about factors linked to a worse health-related quality of life in patients with early systemic sclerosis.

Quality of Life 52

Quality of Life 52