Mon.Dec 09, 2024

article thumbnail

Steven W. Pipe, MD: Fitusiran With Anti-Thrombin Modulation Yields Effective Bleed Control, Reduces Infusions for Hemophilia

HCPLive

Pipe discussed findings from the open-label extension of the ATLAS studies at ASH 2024.

105
105
article thumbnail

Influence of remnant lipoprotein particle cholesterol on non-target lesions progression in patients undergoing percutaneous coronary intervention

Frontiers in Cardiovascular Medicine

BackgroundLow-Density Lipoprotein Cholesterol (LDL-C) is the primary lipid therapy target for coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI). However, progression of coronary atherosclerosis occurs even LDL-C controlled well, some potentially important factors have been overlooked.ObjectiveThis study aims to elucidate the relationship between remnant lipoprotein particle cholesterol (RLP-C) and the progression of non-target lesions (NTLs) in patients with w

article thumbnail

Integration of Cardiovascular Care Into CKD Management

HCPLive

Panelists discuss the role of cardiovascular risk management for patients with chronic kidney disease (CKD) and how cardiovascular care can be effectively integrated into CKD management strategies.

article thumbnail

Analysis offers new explanation for dangerous atherosclerotic plaques in type 2 diabetes

Medical Xpress - Cardiology

People with type 2 diabetes have a higher risk of suffering a stroke, a heart attack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are. Andreas Edsfeldt and Isabel Gonalves, researchers at Lund University Diabetes Centre, have led a study that has mapped out differences in the atherosclerotic process in people who have type 2 diabetes and in people who do not have the disease.

article thumbnail

HepB-CpG Offers Superior Seroprotection in People with HIV, Prior HBV Vaccine Nonresponse

HCPLive

HepB-CpG achieved superior seroprotection response versus conventional HepB-alum in patients with HIV and nonresponse to prior hepatitis B vaccination.

105
105
article thumbnail

Recanalization Does Not Always Equate to Reperfusion: No-Reflow Phenomenon After Successful Thrombectomy

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 183-189, January 1, 2025. BACKGROUND:Thrombectomy for acute large vessel occlusion is a well-established treatment for stroke prevention. However, futile recanalization cases, where no-reflow occurs despite successful recanalization, have been reported. This study aimed to assess cerebral hemodynamics immediately after thrombectomy and their relationship with clinical outcomes.METHODS:We prospectively enrolled patients who underwent successful thrombectomy (modi

article thumbnail

2024 State of Lung Cancer: The Hopes and Hurdles of Precision Oncology with Jacob Sands, MD

HCPLive

In this month's episode of Lungcast, Jacob Sands, MD, discusses the American Lung Associations recently newly-released 2024 State of Lung Cancer report.

Cancer 105

More Trending

article thumbnail

Autonomic Modulation May Benefit Patients with Constipation-Predominant IBS

HCPLive

Study findings highlight systemic and local autonomic imbalance in patients with IBS-C, pointing to the value of autonomic modulation in this population.

103
103
article thumbnail

Dr. McGuire, Dr. Jastreboff and Dr. C Michael Gibson discuss the SURMOUNT 1 Trial of Tirzepatide and how we may be able to diminish the progression from pre-diabetes to diabetes.

Clinical Trial Results

Disclosures: TBD

article thumbnail

Sexual and Physical Assaults are Common Life Stressors for Women in Iceland, Linked to PTSD

HCPLive

A study found 66.4% of participants with probable PTSD had a life stressor of unwanted sexual experiences.

98
article thumbnail

Physical Activity and CVD Risk in Cancer Survivors

American College of Cardiology

How do changes in physical activity levels before and after a cancer diagnosis affect the risk of developing cardiovascular diseases (CVDs) in cancer survivors?

Cancer 65
article thumbnail

Significance of Proteinuria for Potential IgAN

HCPLive

Panelists discuss how clinicians determine the significance of proteinuria in assessing patients for potential IgA nephropathy (IgAN), including the levels and patterns that prompt further investigation and the specific diagnostic red flags that may suggest IgAN over other kidney disorders.

97
article thumbnail

Vandalia Health launches telecardiology service for rural patients

Becker's Hospital Review - Cardiology

Charleston, W.Va.-based Vandalia Healths Mon Health Heart & Vascular Center has launched a new telecardiology service in partnership with the system's Webster Springs, W.Va.-based Webster Memorial Hospital.

article thumbnail

Achieving Quick Responses in Sickle Cell Anemia With Early, Appropriate Hydroxyurea Dosing, with Abena Appiah-Kubi, MD, MPH

HCPLive

Appiah-Kubi also noted that despite elevated HbF levels, very young children with SCA already had anemia and reticulocytosis.

59
article thumbnail

Association between waist-to-hip ratio and risk of myocardial infarction: a systematic evaluation and meta-analysis

Frontiers in Cardiovascular Medicine

BackgroundMyocardial infarction(MI) is one of the most serious health threats. Despite the increasing number of clinical methods used to predict the onset of MI, the prediction of MI is still unsatisfactory and necessitates new methods.ObjectiveTo systematically review observational studies from the past two decades on the association between waist-to-hip ratio (WHR) and MI risk.MethodsOriginal literature on the correlation between WHR and MI was searched in PubMed, Embase, Web of Science, Cochr

article thumbnail

Atogepant Improves Quality of Life in Individuals with Chronic, Episodic Migraine

HCPLive

A recent study examined the phase 3 trials ADVANCE, PROGRESS, and ELEVATE and saw atogepant 60 mg as a preventive migraine treatment improves quality of life and functioning.

article thumbnail

Associations between self-reported sleep duration and incident cardiovascular diseases in a nationwide prospective cohort study of Chinese middle-aged and older adults

Frontiers in Cardiovascular Medicine

PurposeThis study explores the correlation between sleep duration and cardiovascular disease (CVD) among middle-aged and older adults in China. Furthermore, we aim to investigate the association between sleep duration and incident CVD in this population, while assessing potential variations across different age and gender subgroups.MethodsUtilizing data from the nationwide prospective survey of the China Health and Retirement Longitudinal Study (CHARLS) conducted in 2011, 2013, 2015, and 2018, i

article thumbnail

Early-Stage vs Advanced CKD Treatment

HCPLive

Panelists discuss the treatment options available for patients with early-stage versus advanced chronic kidney disease (CKD) and how these options should be tailored to individual patient conditions, as well as the mechanism of action of nonsteroidal mineralocorticoid receptor antagonists (MRAs) such as finerenone and their comparison to other treatment modalities.

article thumbnail

Elucidating the neural mechanisms of stress-induced cardiovascular responses

Medical Xpress - Cardiology

Under stress, animals change their behavior, such as through "fight or flight" or "freezing" response. Simultaneously, physiological responses essential for stress adaptation are triggered in the body. Cardiovascular regulation, including changes in blood pressure and heart rate, is a critical stress response.

article thumbnail

Cardiology MCQ: Echo Basics

All About Cardiovascular System and Disorders

Speed of ultrasound in body tissues is around: A. 20,000 meters per second B. 1500 meters per second C. 340 meters per second D. 10,000 meters per second Correct answer: B. 1500 meters per second Speed of ultrasound is almost that in water, though there is some difference between various tissues. Reflections of ultrasound occur at interfaces between tissues and between blood and tissues, due to the difference in velocity.

article thumbnail

Managing supraventricular tachyarrhythmia in pregnant patients within the emergency department

Frontiers in Cardiovascular Medicine

BackgroundPregnancy increases the risk of supraventricular tachycardia (SVT) due to physiological changes. This study reviews the management of SVT in pregnant patients in the emergency department (ED).MethodsWe retrospectively analyzed 15 pregnant patients with SVT treated at Shenzhen Second People's Hospital ED from 2015 to 2023. Treatments included vagal nerve stimulation, pharmacotherapy, esophageal pacing, cardioversion, and radiofrequency ablation.ResultsThe average patient age was 30.3 ye

article thumbnail

New York hospital launches heart center expansion

Becker's Hospital Review - Cardiology

Auburn (N.Y.) Community Hospital broke ground on an expansion to its heart institute while launching a $50 million fundraising campaign to support additional improvement projects, according to a Dec. 6 report from The Citizen.

article thumbnail

Association between trimethylamine N-oxide and prognosis of patients with myocardial infarction: a meta-analysis

Frontiers in Cardiovascular Medicine

BackgroundTrimethylamine N-oxide (TMAO) has been widely explored and considered as a biomarker for adverse cardiovascular events. However, the relationships between TMAO adverse cardiovascular events are inconsistent in patients. Therefore, this meta-analysis aimed to estimate association between TMAO levels and the prognosis of patients with myocardial infarction (MI).MethodsWe searched PubMed, EMBASE, the Cochrane Library, and Web of Science from inception to July 2, 2023, to retrieve all rele

article thumbnail

Pediatric cardiac physicians group joins BayCare

Becker's Hospital Review - Cardiology

Cardiologists from Pediatrix Cardiology Associates and the Tampa Bay Adult Congenital Heart Center have joined Clearwater, Fla.-based BayCare Health System's physician practice, BayCare Medical Group.

article thumbnail

Highlighting the Danger of SCI Progression during iTTP Remission, with Shruti Chaturvedi, MBSS, MS

HCPLive

Chaturvedi discussed findings from the NeST study at ASH 2024, including an increased risk of stroke in those with silent cerebral infarction progression.

Stroke 52
article thumbnail

HonorHealth team debuts valve replacement procedure in Arizona

Becker's Hospital Review - Cardiology

A team at HonorHealth Scottsdale (Ariz.) Shea Medical Center performed the state's first tricuspid valve replacement using the Edwards Lifesciences' Evoque system outside of a clinical trial.

article thumbnail

Proteinuria Variability and IgAN Diagnosis

HCPLive

Panelists discuss how clinicians determine the significance of proteinuria in assessing patients for potential IgA nephropathy (IgAN), including the levels and patterns that prompt further investigation and the specific diagnostic red flags that may suggest IgAN over other kidney disorders.

52
article thumbnail

Texas hospital team 1st in US to use new pulsed ablation tech

Becker's Hospital Review - Cardiology

A team at Austin, Texas-based St. David's Medical Center became the first team in the U.S. to use a newly FDA-approved novel pulsed field ablation system to treat patients with atrial fibrillation.

article thumbnail

ACC Practice Made Perfect: Measuring Success in Cardiovascular Strategic Planning

American College of Cardiology

Welcome to the Cardiovascular (CV) Dyad Leadership Strategic Planning Series! In this fourth and final episode, Ms. Ellie Huff will interview Mr. Bart Reeves and Dr. Geoffrey Rose on how to measure and track success after a strategic plan has been developed and implemented within the CV Service Line.

Article 45
article thumbnail

Insights From a 20-Year Follow-Up of the First Heart Transplant Recipient to Complete an Ironman Triathlon

Circulation: Heart Failure

Circulation: Heart Failure, Ahead of Print.

article thumbnail

Risks Associated With As-Needed BP Medication

American College of Cardiology

What are the risks of as-needed blood pressure (BP) medication administration, either as a one-time dose or recurring pro re nata (PRN), in asymptomatic patients in the hospital setting?

article thumbnail

Cognitive and Procedural Competencies in the Cardiac Intensive Care Unit

Circulation: Heart Failure

Circulation: Heart Failure, Ahead of Print.

article thumbnail

Do Amyloid Cerebral Deposits Influence the Long-Term Poststroke Cognitive Outcome?: The IDEA3 Study

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. The primary objective of the present study of the IDEA3 (Imagerie des dpts amylodes crbraux par florbetapir AV-45 et diagnostic des dficits cognitifs et dmence post Accident Vasculaire Crbral) cohort was to determine

article thumbnail

One type of blood pressure med may help prevent post-stroke epilepsy

Medical Xpress - Cardiology

Some people develop epilepsy after surviving a stroke, as the injury they've sustained causes scarring and disorganized electrical activity in their brains.

article thumbnail

Association of Duration of Recognized Hypertension and Stroke Risk: The REGARDS Study

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 105-112, January 1, 2025. BACKGROUND:The focus for reducing hypertension-related cardiovascular disease is the management of blood pressure. Limited data are available on the potential benefit of delaying the onset of hypertension.METHODS:Stroke-free Black and White participants from the REGARDS cohort study (Reasons for Geographic and Racial Differences in Stroke; recruited 20032007) were followed through 2022 for incident stroke events.

article thumbnail

Stroke risk may climb as the years of living with high blood pressure add up

Medical Xpress - Cardiology

Delaying the onset of high blood pressure may lower the risk of a stroke, new research suggests.

article thumbnail

Incidence and Predictors of Adverse Events Among Patients Awaiting Left Atrial Appendage Closure

Journal of Cardiovascular Electrophysiology

This study demonstrated a 6% incidence of adverse events among 265 patients awaiting left atrial appendage closure (LAAC). Prolonged time to LAAC and higher HAS-BLED score independently portended a significantly increased hazard for adverse events. Thoughtful risk stratification and expedited closure are warranted in select patients. Incidence and predictors of adverse events among patients awaiting left atrial appendage closure.