Wed.Jan 17, 2024

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Childhood stress linked to higher risk of high blood pressure, obesity, diabetes in adults

American Heart News - Heart News

Research Highlights: Consistently high scores of perceived stress during adolescence through adulthood may contribute to worse cardiometabolic health including obesity in young adults. Researchers suggest the adoption of healthy coping strategies.

Obesity 134
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E-Cigarette Use Not Associated with Adverse Pregnancy Outcomes

HCPLive

These data indicate that e-cigarettes and nicotine patches were found not to negatively impact pregnant smokers in a significant way, though further study may be valuable.

Outcomes 118
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Drinking camel milk can lead to significant reduction in cholesterol levels among diabetics

Medical Xpress - Cardiology

A new study has hailed camel milk for its ability to lower heart disease risk among diabetics and help in the treatment of dyslipidemia.

Diabetes 132
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Artificial Intelligence Helps Coronary CT Angiography and Accelerates the Development of Precision Medicine

DAIC

The application of AI technology in the diagnosis of cardiovascular diseases using coronary CT angiography (CCTA) has gradually deepened, and efficient and intelligent methods are optimizing and reshaping the clinical diagnosis pathways, including optimization of image quality, fully automated calculation of calcification score, coronary stenosis, quantitative and qualitative assessment of plaque components, quantification of perivascular and pericardiac fat, and calculation of non-invasive CT-d

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FDA Extends Shelf-Life for Naloxone Nasal Spray

HCPLive

The FDA has extended the shelf-life of 4 mg naloxone hydrochloride nasal spray (Narcan) for nonprescription over-the-counter use from 3 years to 4 years.

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Childhood stress linked to higher risk of high blood pressure, obesity, diabetes in adults

Science Daily - Heart Disease

Young adults who reported higher stress as adolescents were more likely to have high blood pressure, obesity and other cardiometabolic risk factors as adults, finds new study.

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Colchicine in acute myocardial infarction: cardiovascular events at 1-year follow up

Open Heart

Objective In the COVERT-MI randomised placebo-controlled trial, oral administration of high-dose colchicine at the time of reperfusion and for 5 days in acute ST-elevated myocardial infarction did not reduce infarct size but was associated with a significant increase in left ventricular thrombus (LVT) in comparison to placebo. We aimed to assess the 1-year clinical outcomes of the study population.

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Childhood stress linked to higher risk of high blood pressure, obesity, diabetes in adults

Medical Xpress - Cardiology

Young adults who reported higher stress during their teenage years to adulthood were more likely to have high blood pressure, obesity and other cardiometabolic risk factors than their peers who reported less stress, according to new research published in the Journal of the American Heart Association.

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More Nighttime Outdoor Artificial Light May Increase Wet AMD Risk

HCPLive

Exposure to higher levels of outdoor artificial light at night exhibited an increased risk of incident wet age-related macular degeneration.

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AI model predicts death, complications for patients undergoing angioplasty, stents

Medical Xpress - Cardiology

When a person has one or more blocked arteries, providers may choose to conduct a minimally invasive procedure known as percutaneous coronary intervention, or PCI. By inflating a balloon and potentially placing a stent, they can help blood flow more freely from the heart.

Stents 89
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Lives Prolonged for Longtime CRT-D Users With Heart Failure

Med Page Today

(MedPage Today) -- Eligible heart failure patients with a wide QRS complex spent more time alive after use of a cardiac resynchronization therapy defibrillator (CRT-D) compared with an implantable cardioverter-defibrillator (ICD), according to.

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Therapy vs. medication: Comparing treatments for depression in heart disease patients

Medical Xpress - Cardiology

New research by investigators from the Department of Psychiatry and Behavioral Neurosciences at Cedars-Sinai shows that behavioral activation therapy is as effective as antidepressant medications in treating symptoms of depression in patients with heart failure.

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Perceived Stress From Childhood to Adulthood and Cardiometabolic End Points in Young Adulthood: An 18?Year Prospective Study

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundWe investigated how childhood‐to‐adulthood perceived stress patterns predict adult cardiometabolic risk.Methods and ResultsThis study included 276 participants from the Southern California Children's Health Study (2003–2014), and a follow‐up assessment (2018–2021). Perceived stress (Perceived Stress Scale) was initially reported by participants' parents for themselves during early childhood (mean age, 6.3 years), and later self

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Novel protein interactions may serve as biomarker for heart disease

Medical Xpress - Cardiology

Investigators led by Elizabeth McNally, MD, Ph.D., the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine, have discovered previously unknown protein interactions in the heart's atrium that are critical for normal heart function, according to findings published in the Proceedings of the National Academy of Sciences.

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Allogeneic Stem Cell Therapy Falls Short on Stroke Outcomes

Med Page Today

(MedPage Today) -- Bone marrow-derived allogeneic stem cell therapy shortly after ischemic stroke did not improve outcomes at 90 days, a phase II/III randomized clinical trial known as TREASURE found. The rate of excellent outcomes -- a composite.

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New research finds half-cardio, half-strength training reduces cardiovascular disease risks

Medical Xpress - Cardiology

Approximately one in three deaths in the U.S. is caused by cardiovascular disease, according to the U.S. Centers for Disease Control and Prevention. A robust body of evidence shows aerobic exercise can reduce risks, especially for people who are overweight or obese.

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Long-Term Outcomes of Resynchronization–Defibrillation for Heart Failure

The New England Journal of Medicine

Follow-up at a median of nearly 14 years showed a survival benefit for patients who received cardiac resynchronization with a defibrillator as compared with those who received a defibrillator alone.

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Lipoprotein(a): What to know about elevated levels

Medical Xpress - Cardiology

If you've listened to the radio or opened a webpage in the past year, you may have seen or heard ads promoting lipoprotein(a), or Lp(a), testing to help people identify risks for heart disease.

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Lipoprotein(a) Is Markedly More Atherogenic Than LDL

American College of Cardiology

Is the atherogenicity of Lp(a) greater than LDL based on the contribution of each to the number of apoB particles considering that both contain one apoB molecule per particle?

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The rodent models of arteriovenous fistula

Frontiers in Cardiovascular Medicine

Arteriovenous fistulas (AVFs) have long been used as dialysis access in patients with end-stage renal disease; however, their maturation and long-term patency still fall short of clinical needs. Rodent models are irreplaceable to facilitate the study of mechanisms and provide reliable insights into clinical problems. The ideal rodent AVF model recapitulates the major features and pathology of human disease as closely as possible, and pre-induction of the uremic milieu is an important addition to

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6 Strategies to Keep Best Talent | Improve Patient Outcomes | NHA

Learning + Leading

The healthcare industry is plagued by high turnover rates, which significantly affect both patient care and the operations of healthcare facilities. The emotionally taxing and demanding nature of healthcare jobs often drives professionals to seek other opportunities. High turnover also affects the morale of remaining staff, increases workload, and can lead to a decline in patient care quality.

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Oral anticoagulants increased 30-day survival in sepsis patients complicated with atrial fibrillation: a retrospective analysis from MIMIC-IV database

Frontiers in Cardiovascular Medicine

Background The severity of sepsis is associated with systemic clotting activation. Atrial fibrillation (AF) is the most commonly observed arrhythmia in patients with sepsis and can lead to a poor prognosis. The aim of this study is to elucidate the association between oral anticoagulants and survival from septic patients complicated with AF. Methods The data of 8,828 septic patients, including 2,955 AF and 5,873 without AF, were all originated from the Medical Information Mart for Intensive Care

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NHANES Data Links Iron Deficiency to Risk of Depression in Young Men

HCPLive

Analysis finds measures of iron deficiency, including ferritin, serum iron, and transferrin, were linked to an increased likelihood of depression in young adult males but not females.

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Case Report: Carcinoid heart disease with severe tricuspid regurgitation and concomitant patent foramen ovale causing severe hypoxia

Frontiers in Cardiovascular Medicine

This case report demonstrates a unique case of managing complex concomitant structural cardiac issues using transcatheter techniques in a frail patient. The primary regurgitant lesion in this case caused significant right to left shunting with severely debilitating hypoxaemia for the patient, requiring high volumes of ambulatory oxygen to compensate.

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Spider venom heart drug a step closer

Science Daily - Heart Disease

A molecule sourced from funnel web spider venom shows promise as a safe and effective future drug for heart attacks.

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Surgical vs. Transcatheter MV Replacement for Failed Mitral Prostheses

American College of Cardiology

In patients with failed mitral valve prostheses, what are the clinical outcomes of redo surgical mitral valve replacement (SMVR) versus transcatheter mitral valve replacement (TMVR), and how does hospital case volume relate to outcomes?

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A Conversation on Chronobiology in Medicine, Health, and Performance with Dr. John Hogenesch

Physiologically Speaking

This interview originally appeared on my (now “defunct”) Science & Chill podcast on November 1, 2022. Now, it’s only available to Physiologically Speaking subscribers. I’ll be posting videos twice per month. Be sure to subscribe, because there’s some stellar information in these interviews! Enjoy!

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Smidt Heart Institute Expert Named Deputy Editor of NEJM AI

DAIC

David Ouyang, MD. Photo by Cedars-Sinai milla1cf Wed, 01/17/2024 - 16:16 January 17, 2024 — One of the Smidt Heart Institute ’s leading experts in artificial intelligence, David Ouyang, MD , has been named a deputy editor of NEJM AI — a newly established, peer-reviewed journal from the publishers of the highly respected, New England Journal of Medicine.

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Jacob Ballon, MD, MPH: Discusses Takeaways from Studying Long-Term Olanzapine, Samidorphan

HCPLive

In an interview, Jacob Ballon, MD, MPH, discusses the significance of his team’s study which found olanzapine and samidorphan was well-tolerable for up to 4 years of treatment for schizophrenia and bipolar disorder treatment.

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Nose breathing lowers blood pressure, may help reduce risk factors for heart disease

Medical Xpress - Cardiology

More than half of adults living in the U.S. label themselves as "mouth breathers"—breathing primarily through an open mouth. However, according to new research published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, breathing through the nose leads to several benefits, including lower blood pressure and other factors that could predict heart disease risk.

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Julie Khlevner, MD: Linaclotide for Pediatric Functional Constipation

HCPLive

We sat down with Julie Khlevner, MD, to discuss new efficacy endpoint data from the phase 3 study used to support the FDA approval of linaclotide for pediatric functional constipation.

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DOACs as Nonstandard Treatment: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the-art review on direct oral anticoagulants (DOACs) as nonstandard treatment.

Article 75
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Short-stay units a safe alternative for heart failure patients: Study

Becker's Hospital Review - Cardiology

Researchers found no significant difference in patient outcomes or adverse events for acute heart failure patients treated at a short-stay unit instead of being hospitalized.

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Martina J. Porter, MD: Discussing New Findings on Lutikizumab for HS Patients

HCPLive

In this interview, Porter describes some new and encouraging phase 2 data on lutikizumab treatment for patients with HS who had failed anti-TNF therapy.

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Eagle’s Eye View: False Positive Exercise ECG Tests, Oral Coagulants v. Vitamin K Antagonists, Outcomes Following the Ross Procedure

American College of Cardiology

In this week’s View, Dr. Eagle explores rethinking false positive exercise ECG Tests in patients with microvascular dysfunction. He then discusses a recent comparison of direct oral anticoagulants vs Vitamin K antagonists after transcatheter mitral valve replacement.

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‘When age is not a barrier’: an explorative study of nonagenarian patients’ experiences of undergoing percutaneous coronary intervention

European Journal of Cardiovascular Nursing

Abstract Aims The recent rise in the number of nonagenarians (age ≥ 90 years) undergoing percutaneous coronary intervention (PCI) has revealed gaps in research, in particular on patients’ experiences. Therefore, the aim of the study was to explore and describe nonagenarians’ internal resources and their experiences of the in-hospital pathway. Methods and results Nineteen nonagenarian patients (women n = 9), mean age 91 years, 9 acutely, and 10 electively treated, were consecutively enrolled from

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Artificial intelligence can help coronary CT angiography and accelerate the development of precision medicine

Medical Xpress - Cardiology

With the continuous progress of science and technology, artificial intelligence (AI) has become an important driving force for a new round of scientific and technological revolution and industrial change. It aims to mimic human consciousness and thought processes, continuously learn and improve, and show a response close to or even beyond a real person.