Tue.Nov 07, 2023

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Journal Club 5 Appendicitis Delay to Appendectomy – Safe?

ECG Cases

You diagnose uncomplicated appendicitis in the ED. The on call General Surgery team wants to wait until the next morning to perform an appendectomy. Is your patient at risk for appendiceal perforation with a delay to surgery? Dr. Rohit Mohindra and Dr. Shelley McLeod analyze the latest RCT that attempts to answer this question, the PERFECT study, on this EM Cases Journal Club.

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Left ventricular hypertrophy: an ECG-based study of prevalence and risk factors in a multiethnic population

Open Heart

Background Left ventricular hypertrophy (LVH) is frequently seen in association with arterial hypertension and indicates poor prognosis. This study aimed to determine the prevalence of LVH and associated factors in a multiethnic population from Mauritius. Methods Population-based health surveys were performed in 2009 and 2015 and included in total 8961 individuals aged 35–75 years with recorded 12-lead ECG.

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Ep 188 Hemoptysis – ED Approach and Management

ECG Cases

Key principles and approach to management of both non-massive and massive hemoptysis with Dr. Scott Weingart and Dr. Bourke Tillmann, who answer questions such as: What are the factors to consider in the decision to intubate patients with massive hemoptysis? How can one reliably distinguish hemoptysis from pseudohemoptysis? What is the evidence for tranexamic acid in patients with hemoptysis?

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STS Leadership Institute

Society of Thoracic Surgeons - Surgeon

Event STS Leadership Institute gtrainyte Tue, 11/07/2023 - 12:17 Event dates Mar 21, 2024 – Jan 24, 2025 Location Zoom, Chicago, and Los Angeles The STS Leadership Institute develops skills for cardiothoracic surgeons that have become vital as healthcare delivery grows more complex and rapidly transforms. Physicians who have the necessary leadership skills are essential for medical teams to adapt and work together effectively in order to provide the best patient care.

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Global EM 5 Is it Ethical? 5 Core Principles When Choosing a Global Health Project

ECG Cases

Dr. Navpreet Sahsi outlines 5 core ethical principles in choosing and participating a global health project on EM Cases' Global EM blog. The post Global EM 5 Is it Ethical? 5 Core Principles When Choosing a Global Health Project appeared first on Emergency Medicine Cases.

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Why You Need To Measure apoB To Assess Your Cardiovascular Risk

Dr. Paddy Barrett

The fundamental characteristic of atherosclerosis is when a cholesterol particle becomes trapped in the artery wall. It is the inflammatory response to this particle retention that causes the formation of atherosclerosis 1. Think of it like a tennis ball passing through a net and getting stuck on the other side. Lipoprotein particles entering the subintimal space causing atherosclerosis.

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Anaesthetic Management Of A Patient With Methemoglobinemia: Case Report And Review Of Literature

BMH Medical Journal

Methemoglobinemia is a rare but serious haemoglobin disorder when red blood cells contain methaemoglobin at levels higher than 1%. Basically, it results from the oxidation of the ferrous iron in haemoglobin to the ferric iron. Methaemoglobin is incapable of carrying O 2 , and high levels can impair O 2 delivery to the tissues. Methemoglobinemia can be congenital or acquired.

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Innovations in Lung Tumor Localization: The Latest in Bronchoscopy and Molecular Imaging

Society of Thoracic Surgeons - Surgeon

Webinar Innovations in Lung Tumor Localization: The Latest in Bronchoscopy and Molecular Imaging dkaczmarek Tue, 11/07/2023 - 14:49 November 30, 2023 As sublobar resection becomes more prevalent for early stage lung cancer treatment, precise tumor localization has gained greater importance. Numerous bronchoscopic platforms are available for tumor localization, and a novel molecular imaging agent received FDA approval earlier this year.

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Survival Benefit and Cost Effectiveness of a Future Blood?Based Diagnostic Test to Detect Cerebral Aneurysm Formation

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print. BACKGROUNDCerebral aneurysms are common, but there is no blood test for their diagnosis. Cerebral aneurysms are diagnosed incidentally or upon rupture. Current diagnostic tools either are invasive or place a large financial burden on the patient. Introduction of a blood test can reduce costs and allow for additional screening.METHODSMarkov decision analytic models were created for different case studies to simulate management within

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Predictors of outcome in a contemporary cardiac sarcoidosis population: Role of brain natriuretic peptide, left ventricular function and myocardial inflammation

European Journal of Heart Failure

BNP, CMR-LVEF and SUVmax in FDG-PET: independent predictors of outcome in a contemporary cardiac sarcoidosis population remaining robust in subgroup subanalysis. AV, atrioventricular; BNP, brain natriuretic peptide; CMR, cardiac magnetic resonance imaging; FDG-PET, fluorodeoxyglucose positron emission tomography; HF, heart failure; LVEF, left ventricular ejection fraction; SCD, sudden cardiac death; SUVmax, maximum standardized uptake value; VT, ventricular tachycardia.

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Natriuretic Peptide Receptor B Protects Against Atrial Fibrillation by Controlling Atrial cAMP Via Phosphodiesterase 2

Circulation: Arrhythmia and Electrophysiology

Circulation: Arrhythmia and Electrophysiology, Volume 16, Issue 11 , Page e012199, November 1, 2023. BACKGROUND:β-AR (β-adrenergic receptor) stimulation regulates atrial electrophysiology and Ca2+homeostasis via cAMP-dependent mechanisms; however, enhanced β-AR signaling can promote atrial fibrillation (AF). CNP (C-type natriuretic peptide) can also regulate atrial electrophysiology through the activation of NPR-B (natriuretic peptide receptor B) and cGMP-dependent signaling.

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O2 pulse slope correlates with stroke volume during exercise in patients with a Fontan circulation

Open Heart

Background Peak oxygen pulse (O 2 pulse=oxygen consumption/heart rate) is calculated by the product of stroke volume (SV) and oxygen extraction. It has been shown to be reduced in patients with a Fontan circulation. However, in the Fontan population, it may be a poor marker of SV. We propose that the slope of the O 2 pulse curve may be more reflective of SV during exercise.

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Vall dHebron Risk Score II for myocardial infarction and cardiac death

Open Heart

Objectives The aim of this study was to create a new Vall d’Hebron Risk Score-II (VH-RS-II) for non-fatal myocardial infarction (MI) and/or cardiac death (CD), excluding patients with coronary revascularisation (CR) during the follow-up. Methods We analysed 5215 consecutive patients underwent gated single photon emission CT (SPECT); 2960 patients (age 64.2±11, male 58.1%) had no previous MI and/or CR, and 2255 patients (age 63.3±11, male 81.9%) had previous MI and/or CR.