Thu.Jun 13, 2024

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Type 1 Diabetes in Older People Has Nearly Tripled Globally Since the '90s

Med Page Today

(MedPage Today) -- Global prevalence of older people living with type 1 diabetes mellitus jumped 180% in the past 30 years, a population-based study found. This represents an increase from 1.3 million people worldwide in 1990 to 3.7 million in.

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Selected startups will advance technology-driven improvements in heart and brain health

American Heart News - Heart News

DALLAS, June 13, 2024 — The American Heart Association, through its Center for Health Technology and Innovation (the Center), has selected five companies to participate in the American Heart Association Heart and Brain Health Accelerator. The AHA.

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FDA Announces Teleflex/Arrow International Recall Arrow FiberOptix and UltraFlex Intra-Aortic Balloon (IAB) Catheter Kits

DAIC

milla1cf Thu, 06/13/2024 - 15:08 June 13, 2024 — The U.S. Food and Drug Administration ( FDA ) announced that Teleflex , and their subsidiary Arrow International , are recalling the Arrow FiberOptix Intra-Aortic Balloon Catheter Kit and Arrow UltraFlex Intra-Aortic Balloon Catheter Kits after finding that a manufacturing error may cause the catheter’s balloon to become overtwisted.

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Breakthrough in predicting sudden cardiac death

Science Daily - Heart Disease

A new computational method developed by physicists can be used to estimate the risk of sudden cardiac death from a one-minute heart rate measurement at rest. The study was carried out in interdisciplinary collaboration between cardiology and computational physics.

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Health, Economic Burden of Comorbid Gout, CKD Projected to Increase Through 2035

HCPLive

Findings highlight an urgent need for improved gout management strategies to reduce costs, improve quality of life, and reduce gout symptoms in patients with comorbid gout and CKD.

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Xeltis Receives IDE Approval from FDA for Initiation of US Pivotal Trial for aXess, its Restorative Vascular Access Conduit

DAIC

Xeltis synthetic restorative pulmonary heart valve evolves into a fully functioning, natural heart valve through colonization by the patient’s own tissue. (Photo: Business Wire) milla1cf Thu, 06/13/2024 - 20:36 June 13, 2024 — Xeltis , a leading developer of transformative implants that enable the natural creation of living and long-lasting vessels, announces that it has gained approval from the US Food and Drug Administration ( FDA ) for an Investigational Device Exemption (IDE) submission to b

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Lp(a), Oxidized Phospholipids Can Predict Progression of Heart Failure, Study Finds

HCPLive

New research reveals that elevated lipoprotein(a) and oxidized phospholipids are independent risk factors for early-stage heart failure progression.

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The Expert Witness re-visits a chest pain Malpractice case using the Queen of Hearts

Dr. Smith's ECG Blog

This case was posted by Eric Funk ( [link] ) , editor of the Expert Witness Newsletter , on his site. Here is the case on his site. He has graciously allowed me to repost it here. It is a case he presented several years ago, but then want to re-visit in light of the Queen of Hearts AI system. Don't miss his analysis and assessment of the Queen of Hearts AI OMI ECG bot -- that assessment is at the very bottom of the post.

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El Camino Health Cardiologist Earns International Award for Achievements in Advancing Cardiovascular Field

DAIC

Image courtesy of El Camino Health milla1cf Thu, 06/13/2024 - 20:33 June 13, 2024 — Frederick St. Goar, MD, medical director at the Norma Melchor Heart & Vascular Institute , was distinguished with the Andreas Grüntzig Ethica Award , the highest global honor in interventional cardiology. Dr. St. Goar received the recognition during a special ceremony in Paris, France, along with esteemed cardiothoracic surgeon, Professor Ottavio Alfieri of San Raffaele Hospital in Milan, Italy.

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Trial identifies method of emergency intubation preoxygenation to decrease risk of hypoxemia and cardiac arrest

Medical Xpress - Cardiology

In current clinical care, most critically-ill adults undergoing emergency tracheal intubation receive preoxygenation through an oxygen mask. Administering supplemental oxygen to patients prior to the start of an intubation procedure increases the oxygen content in the patient's lungs and decreases the risk of hypoxemia, low levels of oxygen in the blood.

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Reteplase versus Alteplase for Acute Ischemic Stroke

The New England Journal of Medicine

In this trial from China involving 1412 patients with acute ischemic stroke presenting within 4.5 hours, the percentage who had an excellent functional outcome at 90 days was 79.5% with reteplase and 70.4% with alteplase.

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Potential JAK Inhibitor Combination Regimens in Dermatology

HCPLive

Matthew Zirwas, MD, discusses the prospect of pairing JAK inhibitors like ruxolitinib cream with other disease-targeting options for conditions including vitiligo and alopecia areata.

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Predictors and 5-Year Outcomes of Pacemaker After TAVR

American College of Cardiology

What are the rates of a permanent pacemaker (PPM) implantation, the predictors of needing a PPM, and long-term clinical outcomes of the third-generation balloon-expandable SAPIEN 3 (S3) transcatheter heart valve (THV)?

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Upadacitinib Led to Sustained, 140-Week Improvements for Atopic Dermatitis Patients

HCPLive

These data, presented at RAD 2024, highlight the potential benefits of upadacitinib for adults and adolescents observed in the Measure Up 1 and Measure Up 2 studies.

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Nitroglycerin to Ameliorate Coronary Artery Spasm During AF Ablation

American College of Cardiology

What is the potential of focal pulsed field ablation (PFA) to provoke coronary spasm during cavotricuspid isthmus ablation, and does nitroglycerin use mitigate the risk of vasospasm in this setting?

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Mental stress linked to increased heart risks in heart disease patients

Medical Xpress - Cardiology

Imagine walking through a park and suddenly spotting a bear. Normally your heart starts beating faster and your blood vessels constrict. That's the sympathetic nervous system preparing your body for a "flight or fight" response. Then, once you reach safety, your parasympathetic nervous system helps calm you down. Eventually, your blood pressure and heart rate return to normal.

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Certolizumab Pegol Offers Consistent Benefit, Regardless of Rheumatoid Factor Levels

HCPLive

An analysis of the REALISTIC trial from EULAR 2024 details the effects of certolizumab pegol in rheumatoid arthritis based on rheumatoid factor levels and prior TNF inhibitor use.

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Statins pioneer dies at 90

Becker's Hospital Review - Cardiology

Discover the life and groundbreaking research of Akira Endo, the Japanese biochemist who helped create statins and received a Lasker Award for his work.

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Biosimilar Introduction Reduces Biologic Prices in the US and Globally

HCPLive

After a biosimilar introduction, the prices of the biologic products—namely, trastuzumab, infliximab, bevacizumab, adalimumab, filgrastim, and pegfilgrastim—were significantly reduced.

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Unlocking Excellence in Healthcare: The Power of Centers of Excellence

ADN Center of Excellence

In the ever-evolving landscape of healthcare, the pursuit of excellence is an unwavering commitment. As medical professionals, strive to provide the highest quality of care, grounded in the latest advancements and best practices. This relentless quest for excellence has given rise to a pioneering concept: Centers of Excellence (CoEs) in healthcare. A Center of Excellence is a collaborative ecosystem that brings together renowned institutions, experienced professionals, and cutting-edge resources

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Low-Pressure Hyperbaric Oxygen Therapy May Aid Pain Management in Women with Fibromyalgia

HCPLive

Findings highlight significant improvements in psychological constructs related to pain and quality of life following an 8-week intervention with hyperbaric oxygen therapy.

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Efficacy of autologous blood patch injection for pneumothorax rate after CT-guided percutaneous transthoracic lung biopsy: a systematic review and meta-analysis

Journal of Cardiothoracic Surgery

Pneumothorax is the most frequent complication after CT-guided percutaneous transthoracic lung biopsy (CT-PTLB). Many studies reported that injection of autologous blood patch (ABP) during biopsy needle withdr.

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FDA Approval of Single-Dose Tralokinumab Autoinjector for Adults with Atopic Dermatitis

HCPLive

This approval by FDA officials allows patients an alternative option to pre-filled syringe, which had been the only choice for those with eczema prescribed tralokinumab.

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Unlocking Excellence in Healthcare: The Power of Centers of Excellence

ADN Center of Excellence

In the ever-evolving landscape of healthcare, the pursuit of excellence is an unwavering commitment. As medical professionals, strive to provide the highest quality of care, grounded in the latest advancements and best practices. This relentless quest for excellence has given rise to a pioneering concept: Centers of Excellence (CoEs) in healthcare. A Center of Excellence is a collaborative ecosystem that brings together renowned institutions, experienced professionals, and cutting-edge resources

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Dupilumab Versus Lebrikizumab with Topical Corticosteroids: Efficacy in Atopic Dermatitis

HCPLive

These data highlighted which drug, in combination with topical corticosteroids, produced the best efficacy results for those with atopic dermatitis.

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Visura Technologies to Feature TEECAD mini for Use with Smaller Transesophageal Echocardiography (TEE) Probes During ASE 2024

DAIC

Medical device company Visura Technologies, Inc. has announced the TEECADE mini, an initiative for the next innovation in transesophageal echocardiography (TEE) imaging technology. The company, led by President & CEO Christine Horton, will be participating in the American Society of Echocardiography Scientific Sessions (ASE 2024) to be held June 14-16 in Portland, OR.

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Necroptosis and immune infiltration in hypertrophic cardiomyopathy: novel insights from bioinformatics analyses

Frontiers in Cardiovascular Medicine

BackgroundHypertrophic Cardiomyopathy (HCM), a widespread genetic heart disorder, is largely associated with sudden cardiac fatality. Necroptosis, an emerging type of programmed cell death, plays a fundamental role in several cardiovascular diseases.AimThis research utilized bioinformatics analysis to investigate necroptosis's implication in HCM.MethodsThe study retrieved RNA sequencing datasets GSE130036 and GSE141910 from the Gene Expression Omnibus (GEO) database.

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The Oasis: Q+A with Sam Bish

Conquering CHD

Sam is a former USMC mortarman and Computer Engineer now stay-at-home dad and caregiver to Cillian. He is the Co-Founder to Heart Warrior Ministries and facilitator to the Oasis, an online gaming group for dads with children who have Congenital Heat Disease. His vision to begin the Oasis began when he was inpatient for a year and wanting to connect with other dads for support and advice who shared the same passion.

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Blood vessels in a dish: the evolution, challenges, and potential of vascularized tissues and organoids

Frontiers in Cardiovascular Medicine

Vascular pathologies are prevalent in a broad spectrum of diseases, necessitating a deeper understanding of vascular biology, particularly in overcoming the oxygen and nutrient diffusion limit in tissue constructs. The evolution of vascularized tissues signifies a convergence of multiple scientific disciplines, encompassing the differentiation of human pluripotent stem cells (hPSCs) into vascular cells, the development of advanced three-dimensional (3D) bioprinting techniques, and the refinement

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"Prednisone Without Side Effects": The JAK Inhibitor Ceiling in Dermatology

HCPLive

Matthew Zirwas, MD, explains why he believes agents like ruxolitinib cream and upadacitinib have become the optimal treatments for atopic dermatitis, hidradenitis suppurativa, and more.

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Emerging Cardiovascular Diagnostics in Cardio-Rheumatology: Exploring FAPI PET-CT

American College of Cardiology

Immune-mediated systemic inflammatory disorders (IMIDs) are associated with an increased risk of cardiovascular disease (CVD), ranging from atherosclerosis to myocarditis and heart failure.

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What Makes JAK Inhibitors Safe in Dermatology

HCPLive

Matthew Zirwas, MD, reviews the clinical discrepancies of certain JAK-targeting therapies and their role in dermatology patient outcomes.

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FDA Update: Multi-Agency Task Force to Combat Illegal E-Cigarettes Announced

American College of Cardiology

The U.S. Food and Drug Administration (FDA) and U.S. Department of Justice announced on June 10 the creation of a multi-agency task force to curb the distribution and sale of illegal e-cigarettes.

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Hydroxyurea Therapy May Affect Fertility in Sickle Cell Disease

HCPLive

Hydroxyurea treatment may impact seminal fluid levels and ovarian reserves in male and female patients with sickle cell disease.

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Transcatheter Heart Valve Explant for Infective Endocarditis

American College of Cardiology

What are the outcomes of patients undergoing transcatheter heart valve (THV) explant in the setting of THV-associated infective endocarditis (IE)?

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Adults with Sickle Cell Report Poor Health-Related Quality of Life Scores

HCPLive

Based on the 36-item Short Form Survey questionnaire, adults with SCD in France report low physical and mental health summary scores.

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A Message from Raja-Elie Abdulnour, MD, NEJM Journal Watch Editor-in-Chief

NEJM Journal Watch - Cardiology

Today's medical professionals need relevant, trusted, and timely medical information more than ever.

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