Fri.May 31, 2024

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ECG Blog #432 — "Should I Shock this Patient?"

Ken Grauer, MD

I was sent the ECG in Figure-1 — without the benefit of any history. Is this VT? What is the 1st thing — that YOU would do? Figure-1: I was sent this ECG without any history. Is this VT? MY Thoughts on Today’s CASE: As tempting as it might be to reach for the defibrillator on seeing the ECG shown in Figure-1 — My initial reaction was different. At 1st glance , my impression from seeing ECG #1 — was that the rhythm is very fast and irregular — with a highly variable QRS morphology — and, without

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American College of Cardiology Announces Care of the Athletic Heart

DAIC

milla1cf Fri, 05/31/2024 - 07:00 May 31, 2024 — In the United States there are over 8 million active athletes. Given the rapid expansion of sports cardiology, cardiovascular care teams must understand contemporary care and practice management strategies for all athletes—from the elite to the exercise enthusiast. The ACC Care of the Athletic Heart conference , taking place in Washington, on June 6-8, aims to provide clinicians with guideline-driven, practical, cardiovascular care strategies to im

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In RA, Poorly Controlled Pain Portends Even More Serious Problems

Med Page Today

(MedPage Today) -- Hospitalization and death were markedly more common among rheumatoid arthritis (RA) patients experiencing more pain and worse self-assessed health, analysis of a prospective Australian registry showed. With 806 RA patients stratified.

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Landmark Study Shows CareDx’s HeartCare Outperforms dd-cfDNA Alone in Identifying Rejection and Patients Experienced Excellent Outcomes with Fewer Biopsies

DAIC

milla1cf Fri, 05/31/2024 - 06:00 May 31, 2024 — CareDx , a leading precision medicine company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers, announced findings from the SHORE ( Surveillance HeartCare Outcomes Registry ) study, one of the largest heart transplant studies of its kind, published in The Journal of Heart and Lung Transplantation.

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Anemia Diagnostic Tests Infrequent, Linked to Low Treatment Rates in CKD

HCPLive

Diagnostic tests for anemia etiology are infrequently ordered, leading to a significant majority of patients with CKD receiving inadequate treatment.

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InfoBionic.Ai and HBox.ai Ink Partnership to Offer the First AI-Driven "Cardiology Clinic of the Future"

DAIC

milla1cf Fri, 05/31/2024 - 06:00 May 31, 2024 — InfoBionic.ai and HBox.ai announced a groundbreaking partnership that brings together the leading AI-driven technology platforms from both companies to offer the first comprehensive cardiovascular care solution for the "Cardiology Clinic of the Future." HBox.ai, known for its unique "Virtual Clinic in a Clinic" model, provides an AI-driven technology platform and services enabling cardiology practices to offer virtual care services to their pa

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Bessel van der Kolk, MD: The Future of MDMA Assisted Therapy in PTSD

HCPLive

Van der Kolk discusses the long-term outlook of MDMA in patients with PTSD and what further outcomes he'd like to see explored in the space.

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Tirzepatide Sheds Pounds in Chinese Adults With BMI as Low as 24

Med Page Today

(MedPage Today) -- Tirzepatide (Zepbound) was effective at reducing body weight in Chinese adults with lower cutoffs for overweight or obesity, the SURMOUNT-CN trial reported. In the study of 210 adults without diabetes, participants on tirzepatide.

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HCA hospital 1st to use new tech in electrophysiology lab

Becker's Hospital Review - Cardiology

Davie-based HCA Florida University Hospital opened a new electrophysiology lab and is the first in the country to use new technology in the lab, it said in a May 30 news release.

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Prognostic effect of triglyceride glucose-related parameters on all-cause and cardiovascular mortality in the United States adults with metabolic dysfunction-associated steatotic liver disease

Cardiovascular Diabetology

Insulin resistance (IR) plays a vital role in the pathogenesis of the metabolic dysfunction-associated steatotic liver disease (MASLD). However, it remains unclear whether triglyceride–glucose (TyG) related pa.

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Preventive Statins Safe & Effective in Older Patients

CardiacWire

There is little consensus on whether or when to use statins for primary CVD prevention in older patients, but a new study in the Annals of Internal Medicine provides compelling evidence for expanding statin use in this population. The researchers analyzed matched pairs of statin and non-statin users without pre-existing CVD in the 60-74 (73,427 pairs), 75-84 (21,340 pairs), and 85+ (2,695 pairs) age groups using EHR data from the Hong Kong Health Authority.

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High stress hyperglycemia ratio predicts adverse clinical outcome in patients with coronary three-vessel disease: a large-scale cohort study

Cardiovascular Diabetology

Coronary three-vessel disease (CTVD) accounts for one-third of the overall incidence of coronary artery disease, with heightened mortality rates compared to single-vessel lesions, including common trunk lesion.

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Physiology Friday #220: How to Wake Up More Alert

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Study Highlights Ongoing Need for Biosimilar Education Among Physicians, Pharmacists

HCPLive

Healthcare professionals who were aware of the safety and efficacy of biosimilars were more likely to prescribe or switch patients to a biosimilar.

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Primary graft dysfunction in heart transplantation: the challenge to survival

Journal of Cardiothoracic Surgery

Primary graft dysfunction (PGD) is a life-threatening clinical condition with a high mortality rate, presenting as left, right, or biventricular dysfunction within the initial 24 h following heart transplantat.

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The Role of Eosinophils in Diagnosing COPD

HCPLive

Focusing on the role of eosinophils in diagnosing COPD, the panel discusses how often they should be tested, the cut-off value, and the natural changes of eosinophils in the disease course.

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Long non-coding RNA MEG3 knockdown represses airway smooth muscle cells proliferation and migration via sponging miR-143-3p/FGF9 in asthma

Journal of Cardiothoracic Surgery

Background Asthma is a respiratory disease characterized by airway remodeling. We aimed to find out the role and mechanism of lncRNA MEG3 in asthma. Methods We established a cellular model of asthma by inducing human airway smooth muscle cells (HASMCs) with PDGF-BB, and detected levels of lncRNA MEG3, miR-143-3p and FGF9 in HASMCs through qRT-PCR. The functions of lncRNA MEG3 or miR-143-3p on HASMCs were explored by cell transfection.

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Understanding How Your Heart Keeps You Going

MIBHS

Have you ever wondered how your heart works tirelessly day in and day out, keeping you alive and kicking? It’s a remarkable organ, a powerful pump that never takes a break. At Minimally Invasive and Bloodless Heart Surgery with Dr. Ciuffo , we’re here to take a journey into the world of your heart, simplified for easy understanding. Meet Your Heart The heart is a muscular organ located slightly to the left of the center of your chest.

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“Decompression illness” on extracorporeal membrane oxygenation

Journal of Cardiothoracic Surgery

Extracorporeal membrane oxygenation (ECMO) is increasingly being used for critically ill patients with cardiopulmonary failure. Air in the ECMO circuit is an emergency, a rare but fatal complication.

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Unmet Needs in the COPD Treatment Landscape

HCPLive

The panel discusses unmet needs in the COPD treatment landscape, highlights the shortcomings of current treatment strategies, and provides insights on diagnostic practices.

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Risk factors of pneumothorax in computed tomography guided lung nodule marking using autologous blood: a retrospective study

Journal of Cardiothoracic Surgery

To investigate the risk factors of pneumothorax of using computed tomography (CT) guidance to inject autologous blood to locate isolated lung nodules.

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Biomarker, Treatment Development Could Help Address Unmet Need in AATD-Related Liver Disease

HCPLive

Using available literature, the review assesses our current understanding of AATD, emerging biomarkers, and the future of drug development.

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The autonomic nervous system and the origins of neurocardiology

Journal of Cardiovascular Electrophysiology

Abstract Following new concepts by Bichat in the early 19th century, of organic and animal life centered around the ganglionic nervous system, over 100 years of anatomic studies and physiologic experimentation eventually resulted in Gaskell's 1916 book entitled “The Involuntary Nervous System” and Langley's 1921 book entitled “The Autonomic Nervous System.

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Treatment Resistance in HIV

HCPLive

Paul E. Sax, MD, and Sorana Segal-Maurer, MD, discuss treatment resistance in HIV and how it has changed over the years.

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Considering Initial “PCI Turndown” as a Risk Factor for Subsequent PCI

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print.

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Greater Salivary Rates Linked to Lower Levels of Psoriasis Disease Severity

HCPLive

A new study found a negative correlation between salivary rates and disease severity for patients with psoriasis.

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Why You Probably Already Have Heart Disease But Just Don't Know It.

Dr. Paddy Barrett

Heart disease is something ‘old people’ need to worry about. Sure. That is true. But so do ‘Young People’ Here’s why. The mistake most people make when it comes to heart disease is thinking that when someone has a heart attack that, the condition of ‘heart disease’ just appeared. Heart attacks present suddenly.