Wed.Apr 02, 2025

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Scientists unveil starfish-inspired wearable tech for heart monitoring

Science Daily - Heart Disease

When we move, it's harder for existing wearable devices to accurately track our heart activity. But researchers found that a starfish's five-arm shape helps solve this problem. Inspired by how a starfish flips itself over -- shrinking one of its arms and using the others in a coordinated motion to right itself -- scientists have created a starfish-shaped wearable device that tracks heart health in real time.

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The Top Trends of ACC.25

CardiacWire

The ACC 2025 meeting is all wrapped up after matching the attendance and excitement of last years expo, with a clear trend toward better diagnostics and even better pharmaceuticals. Among dozens of highlights, here are Cardiac Wires seven biggest trends from ACC.25. Diverse Pharma ACC.25 saw a deluge of pharmaceutical solutions across the spectrum of heart disease, from HCM all the way to LDL (detection and treatment just have to catch up).

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Cardiac Risk in the Young: 30 Years of Supporting Families and Preventing Young Sudden Cardiac Deaths

The British Journal of Cardiology

For more than 30 years, Cardiac Risk in the Young (CRY) has been at the forefront of efforts to prevent sudden cardiac deaths in young people. Established in 1995, CRY has transformed the landscape of cardiac screening, research, and bereavement support in the UK and beyond. Through pioneering research, large-scale screening initiatives, and raising awareness, CRY has saved lives, supported affected families, and driven critical policy changes.

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Evaluation of vascular responses to moderate-intensity continuous and high-intensity interval physical exercise in subjects with elevated blood pressure: a randomised, cross-over clinical trial

Open Heart

Objective In this randomised two-period crossover trial, the objective was to compare acute changes in arterial distensibility between high-intensity interval physical exercise (HIIPE) and moderate-intensity continuous physical exercise (MICPE) sessions in subjects with elevated blood pressure (BP). Methods and analysis Participants underwent either MICPE-HIIPE or HIIPE-MICPE sequences with intensity based on cardiopulmonary exercise testing.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Science Daily - Stroke

Cervical artery dissection is a tear in an artery in the neck that provides blood flow to the brain. Such a tear can result in blood clots that cause stroke. A new study has found almost a five-fold increase in the number of U.S. hospitalizations for cervical artery dissection over a 15-year period.

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'Natural Experiment' Ties Shingles Vaccine to Reduced Dementia Risk

Med Page Today

(MedPage Today) -- Vaccination against herpes zoster, or shingles, was tied to significantly less dementia risk, a large-scale analysis of electronic health records in Wales showed. Receiving the live-attenuated zoster vaccine (Zostavax) reduced.

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Heart failure services from the community perspective in the UK: a cross-sectional survey

The British Journal of Cardiology

Heart failure (HF) is a highly prevalent long-term condition, with variation in services and resources across the UK. This report provides findings from a cross-sectional survey of community HF services in the UK between September 2021 and February 2022. Eighty-five responses describing community HF services were received. Community services were primarily led by a HF specialist nurse (HFSN), with a median of 1.25 cardiology consultants with HF training, and a variety of other nurses and support

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No Increased Diabetes Risk Post-COVID in Highly Vaccinated Group

Med Page Today

(MedPage Today) -- There was no overall increased risk of new-onset type 2 diabetes after SARS-CoV-2 infection in a highly vaccinated and boosted Asian cohort when milder COVID-19 variants were predominant, a study in Singapore showed. Compared.

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Effect of hyperbaric oxygen therapy on LV function in CAD patients after reperfusion based on echo: a meta-analysis

The British Journal of Cardiology

Hyperbaric oxygen therapy (HBOT) is successfully implemented for the treatment of several disorders. HBOT is a promising treatment modality for coronary artery disease (CAD), where outcomes are frequently poor despite early revascularisation. The aim of this study is to investigate the effect of HBOT on the left ventricular function of patients with CAD after reperfusion.

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Rademikibart Yields Rapid Improvements in Moderate to Severe Uncontrolled Asthma

HCPLive

Participants with higher baseline eosinophil levels had the greatest responses and no participants experienced peaks of over 3000 eosinophils/L.

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Being physically active, even just a couple of days a week, may be key to better health

American Heart News - Heart News

Research Highlights: New research suggests that participating in at least 150 minutes of moderate to vigorous physical activity in just two days had similar health benefits as distributing the activity throughout the week. People who followed the.

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Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Medical Xpress - Cardiology

Cervical artery dissection is a tear in an artery in the neck that provides blood flow to the brain. Such a tear can result in blood clots that cause stroke. A new study has found almost a five-fold increase in the number of U.S. hospitalizations for cervical artery dissection over a 15-year period.

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Long-Term Considerations in Angle Closure Glaucoma with Lauren Blieden, MD

HCPLive

Blieden discusses long-term patient management in glaucoma, the importance of follow-up care, and the role of advocacy in ophthalmology.

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World's smallest light-activated pacemaker can be inserted with a syringe, then dissolves after it's no longer needed

Medical Xpress - Cardiology

Northwestern University engineers have developed a pacemaker so tiny that it can fit inside the tip of a syringeand be noninvasively injected into the body.

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Left Atrial Appendage Closure after Ablation for Atrial Fibrillation

The New England Journal of Medicine

After atrial fibrillation ablation, left atrial appendage closure was associated with a lower risk of bleeding than oral anticoagulation and was noninferior to oral anticoagulation with respect to clinical outcomes at 36 months.

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Research suggests being physically active, even just a couple of days a week, may be key to better health

Medical Xpress - Cardiology

Being physically active for one to two days a week, often called a "weekend warrior," may provide comparable health and life-prolonging benefits as smaller doses of daily physical activity if the physical effort is moderate to vigorous and totals 150 minutes a week in line with recommended guidelines for weekly physical activity, according to research published in the Journal of the American Heart Association.

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Association of Accelerometer‐Derived Physical Activity Pattern With the Risks of All‐Cause, Cardiovascular Disease, and Cancer Death

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundCurrent guidelines suggest engaging in a minimum of 150 minutes of moderate to vigorous physical activity (MVPA) each week to support overall health. However, the effect of concentrated versus evenly distributed physical activity (PA) on health outcomes remains uncertain. This study aims to investigate the associations of weekend warrior pattern, where most MVPA is completed in 1 to 2 days, and a more evenly spread MVPA pattern

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The heart remembers: Scientists describe how early-life cardiac injury in parents influences the next generation

Medical Xpress - Cardiology

Stress during the first years of life can have effects that last into adulthood. Less is known, however, about the possible inheritance of the consequences of early-life stress by the next generation. Now, scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the University of Bern in Switzerland have discovered that heart injury early in life in one generation of mice triggers changes in cardiac function in their offspring.

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Subcutaneous Methotrexate Superior to Oral Version in Key Areas for Psoriasis

HCPLive

In this literature review, investigators concluded that subcutaneous injections of methotrexate have some advantages over oral therapy.

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Scientists unveil starfish-inspired wearable tech for heart monitoring

Medical Xpress - Cardiology

When the body moves, it's harder for existing wearable devices to accurately track heart activity. But University of Missouri researchers found that a starfish's five-arm shape helps solve this problem.

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Exercise Therapy in Symptomatic Peripheral Artery Disease: Summary of Current Knowledge and Future Directions

American College of Cardiology

Symptomatic peripheral artery disease (PAD) is increasingly prevalent worldwide and most patients have significant functional impairment even at early stages of disease.

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Psychiatry Month in Review: March 2025

HCPLive

This month in review spotlights phase 2 and 3 trials and discovered associations in the psychiatry field.

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Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours

The New England Journal of Medicine

In patients with posterior circulation stroke for whom thrombectomy was not planned, alteplase administered 4.5 to 24 hours after stroke onset resulted in less disability at 90 days than standard treatment.

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Nephrology Month in Review: March 2025

HCPLive

The March 2025 month in review spotlights a new episode of Crisis Point about CKD for National Kidney Month and renal FDA news.

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Experts challenge aspirin guidelines based on their undue reliance on a flawed trial

Medical Xpress - Cardiology

Recent guidelines have restricted aspirin use in the primary prevention of cardiovascular disease. The American Heart Association (AHA)/American College of Cardiology (ACC) guidelines restricted aspirin to patients under 70, and more recently, the United States Preventive Services Task Force restricted aspirin use to patients under 60. However, heart attack and stroke risks both rise with age, leaving health care providers unsure about when to stop prescribing aspirin, whether it should be used

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Atrasentan (Vanrafia) Receives Accelerated Approval in IgA Nephropathy

HCPLive

The approval indicates Novartis's atrasentan (Vanrafia) for proteinuria reduction in primary IgA nephropathy.

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Eagle’s Eye View: Key Takeaways from ACC.25 Major Trials and Presentations

American College of Cardiology

In this weeks View, Dr. Eagle looks at the major trials and presentations from the recently concluded ACC.25 in Chicago. This episode includes coverage of practice-changing and practice-validating trials including.

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FDA Grants Fast Track to Biogen’s Tau-Targeting BIIB080 for Alzheimer Disease

HCPLive

The FDA granted fast-track status to Biogens BIIB080, a tau-targeting therapy for Alzheimer Disease, which is now being evaluated in the global phase 2 CELIA study.

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Ketamine as part of multi-modal analgesia may reduce opioid requirements following cardiac surgery: a retrospective observational cohort study

Journal of Cardiothoracic Surgery

Postoperative pain control in cardiac surgery is often managed with opioid medications. Insufficient analgesia can result in complications including splinting, pneumonia, and delay of appropriate rehabilitatio.

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Bariatric Surgery Cost-Effective for Patients with Obesity, Cirrhosis

HCPLive

Bariatric surgery was associated with improved overall survival at an acceptable health care cost within a 10-year horizon.

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Associations between cardiometabolic indices and the onset of metabolic dysfunction-associated steatotic liver disease as well as its progression to liver fibrosis: a cohort study

Cardiovascular Diabetology

This study sought to examine the associations between cardiometabolic indices and the onset of metabolic dysfunction-associated steatotic liver disease (MASLD) as well as its progression to liver fibrosis.

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Influencing factors and predictive indicators of return of spontaneous circulation in in-hospital cardiac arrest

Frontiers in Cardiovascular Medicine

BackgroundIn-hospital cardiac arrest (IHCA) refers to the occurrence of cardiac arrest in hospitalized patients requiring chest compressions and/or defibrillation, with only about one-third of patients achieving return of spontaneous circulation (ROSC) after cardiopulmonary resuscitation. Pan-immune-inflammation value (PIIV) is an indicator assessing the overall inflammatory status within the body, but the relationship between PIIV and ROSC remains unclear.ObjectiveThis study aims to analyze the

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Opthea Announces Termination of ShORe and COAST Trials of Sozinibercept

HCPLive

The treatment for wet age-related macular degeneration failed to achieve its primary endpoint in both trials.

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Association between triglyceride-glucose index and all-cause mortality in patients with congestive heart failure and atrial fibrillation

Frontiers in Cardiovascular Medicine

BackgroundThe role of the triglyceride-glucose (TyG) index in critically ill patients with congestive heart failure (CHF) and atrial fibrillation (AF), requiring intensive care unit (ICU) admission, remains unclear. This study aimed to investigate the association between the TyG index and the clinical prognosis of critically ill patients with CHF and AF.MethodsThis retrospective observational cohort study utilized data from the Medical Information Mart for Intensive Care-IV (MIMIC IV2.2) databas

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Rheumatology Month in Review: March 2025

HCPLive

The rheumatology month in review emphasizes new research in gout, fibromyalgia, and psoriatic arthritis.

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Efficacy of ivabradine in patients with poor heart rate control after beta-blocker use in acute myocardial infarction: a pragmatic randomized controlled trial

Frontiers in Cardiovascular Medicine

IntroductionA rapid resting heart rate following acute myocardial infarction (AMI) predicts poor prognosis, making heart rate control crucial in treatment. Ivabradine is commonly used as a second-line therapy when beta-blockers are poorly tolerated. However, its efficacy in improving cardiac function and prognosis compared to beta-blockers alone remains unclear.