DAIC

JANUARY 15, 2024

Image courtesy of Ultromics milla1cf Mon, 01/15/2024 - 12:54 January 15, 2024 — Ultromics , a patient outcomes-focused AI-driven health technology company with roots at the University of Oxford, UK, has entered into an agreement with Pfizer to support the validation and FDA clearance of its AI-based technology for the detection of cardiac amyloidosis.

Ultrasound 119

Ultrasound Coronary Artery Disease Innovation Heart Failure 119

HCPLive

JANUARY 15, 2024

Autonomous AI increases diabetic eye exam completion rates in a diverse population of youth with diabetes.

Diabetes 130

Diabetes 130

DAIC

JANUARY 15, 2024

A public-private partnership Think Tank, focused on leveraging remote monitoring for cardiac safety in clinical trials, has been announced by the Cardiac Safety Research Consortium, CSRC, to be held Feb. 29-Mar. 1, 2024 in San Diego, CA, and will include representatives from the FDA, academia and industry. Image courtesy: CSRC christine.book Mon, 01/15/2024 - 13:36 January 15, 2024 — A public-private partnership Think Tank, scheduled for Feb. 29-March 1, will be presented by the Cardiac Safety R

Research 116

Research Academic Best Practices Technology 116

Science Daily - Heart Disease

JANUARY 15, 2024

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say.

Sudden Cardiac Death 102

Sudden Cardiac Death Arrhythmia 102

DAIC

JANUARY 15, 2024

Larry Goldstein, M.D., chair of the University of Kentucky Department of Neurology. Photo by Shaun Ring. milla1cf Mon, 01/15/2024 - 12:47 January 15, 2024 — Larry Goldstein , M.D. , chair of the University of Kentucky Department of Neurology , has been selected to serve as co-chair of The Kentucky Heart Disease and Stroke Prevention (KHDSP) Task Force representing stroke systems of care across the state.

Heart Disease 105

Heart Disease Strokes Stroke Public Health 105

HCPLive

JANUARY 15, 2024

Screening for liver fibrosis was associated with sustained improvements in alcohol consumption, diet, weight, and exercise in individuals at risk of ALD and MASLD.

Diet 103

Diet Exercise 103

Cassling

JANUARY 15, 2024

As Director of Project Management at Cassling, Toby Vincent has seen more projects through to completion than maybe anyone. And it’s his perseverance and willingness to get every detail ironed out early on that has enabled him to achieve remarkable growth with Cassling over the past two decades. As Toby celebrates 20 years with the company, those who know him best were willing to share just what makes Toby such an indispensable part of our team.

Blog 98

Blog 98

HCPLive

JANUARY 15, 2024

Patients with gout had a 1.26-fold higher likelihood of experiencing migraines when compared with those without gout.

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Medical Xpress - Cardiology

JANUARY 15, 2024

Phosphodiesterase type 5 inhibitors (PDE5i)—an erectile dysfunction drug sold under the names Viagra, Levitra, Cialis, and others—are a common medical treatment for erectile dysfunction (ED) in men with cardiovascular disease (CVD). However, a new Swedish study published in the Journal of the American College of Cardiology suggests that patients are at higher risk for morbidity and mortality over time when PDE5is and nitrate medication are both prescribed.

Chest Pain 91

Chest Pain Cardiovascular Disease 91

HCPLive

JANUARY 15, 2024

Benign prostatic hyperplasia was 1.13-fold higher in those with gout when compared with controls.

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Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Background The diagnosis of a left ventricular (LV) thrombus in patients with ST-segment elevation myocardial infarction (STEMI) remains challenging. The aim of the current study is to characterize clinical predictors for LV thrombus formation, as detected by cardiac magnetic resonance imaging (CMRI). Methods We retrospectively evaluated 337 consecutive STEMI patients.

Myocardial Infarction 80

Myocardial Infarction STEMI Hospital 80

Medical Xpress - Cardiology

JANUARY 15, 2024

A new 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials in a paper titled "Atherosclerotic three-layer nanomatrix vascular sheets for high-throughput therapeutic evaluation.

Atherosclerosis 79

Atherosclerosis Research 79

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Background Contemporary management of spontaneous coronary artery dissection (SCAD) is still controversial. This systematic review of the literature aims to explore outcomes in the patients treated with conservative management vs. invasive strategy. Methods The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed when we extensively searched three electronic databases: PubMed, ScienceDirect, and Web of Science, for studies that compared conservativ

SCAD 75

SCAD Coronary Artery Bypass Graft Outcomes Myocardial Infarction 75

Circulation

JANUARY 15, 2024

Circulation, Ahead of Print. BACKGROUND:During the neonatal stage, the cardiomyocyte undergoes a constellation of molecular, cytoarchitectural, and functional changes known collectively as cardiomyocyte maturation to increase myocardial contractility and cardiac output. Despite the importance of cardiomyocyte maturation, the molecular mechanisms governing this critical process remain largely unexplored.METHODS:We leveraged an in vivo mosaic knockout system to characterize the role ofCarm1, the f

Electrophysiology 81

Electrophysiology Heart Disease Ablation Circulation 81

Dr. Smith's ECG Blog

JANUARY 15, 2024

Written by Colin Jenkins. Colin is an emergency medicine resident beginning his critical care fellowship in the summer with a strong interest in the role of ECG in critical care and OMI. Edits by Willy Frick. A patient in their 40s with type 1 diabetes mellitus and hyperlipidemia presented to the emergency department with 5 days of “flu-like” illness.

Chest Pain 64

Chest Pain Blog Critical Care Arrhythmia 64

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Background Catheter ablation (CA) for symptomatic atrial fibrillation (AF) offers the best outcomes for patients. Despite the benefits of CA, a significant proportion of patients suffer a recurrence; hence, there is scope to potentially improve outcomes through technical innovations such as ablation index (AI) guidance during AF ablation. We present real-world 5-year follow-up data of AI-guided pulmonary vein isolation.

Ablation 64

Ablation Atrial Fibrillation BMI Arrhythmia 64

HCPLive

JANUARY 15, 2024

In this subgroup analysis data shown at Winter Clinical, findings indicated IGA success with topical roflumilast foam among seborrheic dermatitis patients.

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Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Objectives To evaluate the results of the inoperable and operable with aortic valve endocarditis, focus on risk factors, significance, and management of destruction of the aortic annulus in aortic valve endocarditis. Methods The retrospective study was completed to investigate patients with aortic valve endocarditis undergoing cardiac surgery between January 2006 and November 2022 at our hospital.

Aortic valve 64

Aortic valve Aortic Best Practices Risk Factors 64

HCPLive

JANUARY 15, 2024

Data from a new study suggests the Montreal Cognitive Assessment cut points should be lowered for both English and Spanish screenings for more accurate cognitive impairment screenings.

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Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Introduction The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in extracorporeal cardiopulmonary resuscitation (eCPR) has emerged as a treatment option for selected patients who are experiencing refractory cardiac arrest (CA). In the light of increasing availability, the analyses of outcome-relevant predisposing characteristics are of growing importance.

Cardiogenic Shock 64

Cardiogenic Shock Cardiac Arrest BMI Coronary Artery Disease 64

DAIC

JANUARY 15, 2024

tim.hodson Mon, 01/15/2024 - 10:48 HeartFlow is offering a free webinar based on a recent study that measured the ability of the of its roadmap analysis to support CCTA reading efficiency, confidence and reproducibility (SMART-CT. The presenters are Michael Morris, MD , and Wesley O’Neal, MD. Morris is Director of Cardiac MR and Cardiac CT at Banner Health , Phoenix, Arizona, and O’Neal, is Director of Cardiac CT and Nuclear Cardiology at Cone Health , Greensboro, North Carolina.

Webinar 59

Webinar Stenosis 59

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Recently, the use of assisted reproductive technology (ART) has rapidly increased. As a result, an increasing number of people are concerned about the safety of offspring produced through ART. Moreover, emerging evidence suggests an increased risk of cardiovascular disease (CVD) in offspring conceived using ART. In this review, we discuss the epigenetic mechanisms involved in altered DNA methylation, histone modification, and microRNA expression, as well as imprinting disorders.

Technology 59

Technology Cardiovascular Disease Risk Factors 59

HCPLive

JANUARY 15, 2024

Results of the PRECISION trial suggest use of iron-whey-protein microspheres could aid in improving adherence to oral iron therapy as well as staving off adverse GI events.

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American College of Cardiology

JANUARY 15, 2024

In this episode, Drs. Thachil and Sinha interview the co-directors and co-founders of the New York University (NYU) Langone Critical Care Cardiology Symposium, Drs. Carlos Alviar and James Horowitz.

Critical Care 63

Critical Care Education Article 63

Cardiovascular Ultrasound

JANUARY 15, 2024

Swine are frequently used as animal model for cardiovascular research, especially in terms of representativity of human anatomy and physiology. Reference values for the most common species used in research are.

Anatomy 52

Anatomy Physiology Research 52

HCPLive

JANUARY 15, 2024

Results of the retrospective study suggested blood pressure, serum IgA, potassium, and segmental glomerulosclerosis may be predictive of the rapid progression of renal endpoints in patients with concurrent IgAN and membranous nephropathy.

Blood Pressure 52

Blood Pressure Outcomes 52

MIBHS

JANUARY 15, 2024

Coronary artery bypass surgery (CABG) has been a cornerstone in the treatment of coronary artery disease (CAD), providing a lifeline for individuals with blocked or narrowed arteries. Traditionally, CABG involved a sternotomy, a procedure requiring a sizable incision through the chest, but the landscape of cardiac surgery has transformed the way we cure coronary artery disease.

Coronary Artery Disease 52

Coronary Artery Disease Stent Stents Outcomes 52

HCPLive

JANUARY 15, 2024

These data, presented at the Winter Clinical conference, showed that roflumilast cream 0.15% led to positive results for patients with eczema.

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Circulation

JANUARY 15, 2024

Circulation, Volume 149, Issue 3 , Page 270-273, January 16, 2024.

COVID-19 83

COVID-19 Circulation 83

HCPLive

JANUARY 15, 2024

Prescribing phosphodiesterase type 5 inhibitors and nitrates together may increase the risk of morbidity and mortality for patients over time.

Chest Pain 52

Chest Pain 52

Circulation

JANUARY 15, 2024

Circulation, Volume 149, Issue 3 , Page 267-269, January 16, 2024.

Congenital 81

Congenital Circulation 81

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Introduction Dual antithrombotic therapy (DAT) combining oral anticoagulation (OAC), preferentially Non-vitamin K antagonist OAC (NOAC) and single antiplatelet therapy (SAPT) for a period of 6–12 months is recommended after percutaneous coronary intervention (PCI) in patients with an indication for OAC. Objective To compare outcomes between vitamin K antagonist (VKA) and NOAC-treated patients in the nation-wide France PCI registry.

Myocardial Infarction 64

Myocardial Infarction Academic Research Strokes 64

HeartRhythm

JANUARY 15, 2024

Early repolarization syndrome (ERS) is an idiopathic ventricular fibrillation (VF) associated with inferolateral J waves. While electrical storms (ES) in ERS is not rare, their characteristics and risk factors are not fully understood.

Risk Factors 45

Risk Factors 45

Circulation

JANUARY 15, 2024

Circulation, Volume 149, Issue 3 , Page 251-266, January 16, 2024. Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis. Its role in atherosclerosis holds great interest because the presence and burden of coronary calcification provide direct evidence of the presence and extent of coronary artery disease; furthermore, CAC predicts future events independently of concomitant conventional cardiovascular risk factors and to a greater extent than any other nonin

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

HCPLive

JANUARY 15, 2024

Dr Greg Mattingly reviews the results of GEMINI and ASCEND trials, which led to approval of dextromethorphan-bupropion.

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Circulation: Cardiovascular Interventions

JANUARY 15, 2024

Circulation: Cardiovascular Interventions, Volume 17, Issue 1 , Page e013006, January 1, 2024. BACKGROUND:We previously reported the use of minimal stent area to predict angiographic in-stent restenosis after drug-eluting stent implantation for unprotected left main (LM) disease. We aimed to evaluate the optimal minimal stent area criteria for up-front LM 2-stenting based on long-term clinical outcomes.METHODS:We identified 292 consecutive patients with LM bifurcation stenosis who were treated u

Stent 40

Stent Stents Myocardial Infarction Stenosis 40

Circulation: Cardiovascular Imaging

JANUARY 15, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e016138, January 1, 2024. BACKGROUND:Guidelines propose the inclusion of quantitative measurements from82Rubidium positron emission tomography (RbPET) to discriminate obstructive coronary artery disease (CAD). However, the effect on diagnostic accuracy is unknown. The aim was to investigate the optimal RbPET reading algorithm for improved identification of obstructive CAD.METHODS:Prospectively enrolled patients (N=400) underwent RbPE

Coronary Artery Disease 40

Coronary Artery Disease Stenosis Cardiovascular Imaging Circulation 40