Dr. Paddy Barrett
FEBRUARY 21, 2025
“There are decades where nothing happens; and there are weeks where decades happen.” Vladimir Ilyich Lenin. It always feels strange to quote Lenin, but when it comes to weight loss medications, it is hard not to feel that decades are happening right before our eyes. For over 50 years, rates of those who are overweight or obese have been rising rapidly.
CardiacWire
FEBRUARY 21, 2025
Competition breeds innovation, and thats good news for ATTR-CM patients who could have three different drugs to choose from: Vyndaqel (Pfizer), Attruby/Beyonttra (BridgeBio), and Amvuttra (Alnylam). ATTR-CM affects more than 120k Americans with 5-7k new cases each year, but underdiagnosis means there could be even more. The disease occurs when misfolded proteins build up in the heart and stiffen the heart muscle, leading to heart failure.
Hypertension Journal
FEBRUARY 21, 2025
Hypertension, Ahead of Print. BACKGROUND:A hypertensive disorder of pregnancy is associated with a higher risk of cardiovascular disease later in life, but the potential mechanistic links are unknown.METHODS:We recruited 2 groups of women, 1 during pregnancy and another at least 2 years after delivery. Cases had a hypertensive disorder of pregnancy, and controls had a normotensive pregnancy.
Med Page Today
FEBRUARY 21, 2025
(MedPage Today) -- The shortage of semaglutide injections (Ozempic, Wegovy) is over, the FDA announced on Friday. The agency, along with maker Novo Nordisk, confirmed that supply now meets or exceeds both the current and projected U.S. demand.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Medical Xpress - Cardiology
FEBRUARY 21, 2025
A positive patient-doctor relationship is an ingredient to a healthy life, and new research has zeroed in on the impact common language in the relationship can have by decreasing cardiovascular disease for the benefit of a longer life.
HCPLive
FEBRUARY 21, 2025
Alvotech and Teva announced that the biosimilar will be interchangeable with the reference after ustekinumab-auubs exclusivity expires in April 2025.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
FEBRUARY 21, 2025
A study analyzed hypersensitivity reactions to biologics for atopic diseases, highlighting reaction types, severity, and biologic discontinuation rates.
Journal of Cardiothoracic Surgery
FEBRUARY 21, 2025
Pericardial effusion is a relatively common complication associated with inflammatory and non-inflammatory diseases. The primary etiology of this condition could be considered when choosing therapeutic options.
HCPLive
FEBRUARY 21, 2025
The US supply of semaglutide and semaglutide 2.4 mg now meets or exceeds current and projected demand, ending the long-running shortages of these blockbuster drugs.
Cardiovascular Diabetology
FEBRUARY 21, 2025
The recent discovery of clinically significant data, alongside novel physiological and pathological occurrences surrounding sacubitril/valsartan (Sac/Val) beyond its approved indications, necessitates an urgen.
HCPLive
FEBRUARY 21, 2025
A meta-analysis found oral immunotherapy improves health-related quality of life post-food allergy treatment, but benefits during treatment remain unclear.
Medical Xpress - Cardiology
FEBRUARY 21, 2025
One of the NBA's most exciting rising stars will spend the rest of the 20242025 season on the bench.
HCPLive
FEBRUARY 21, 2025
Investigators in China developed a patch test designed for hair care products tailored to clinical needs such as those of patients with conditions like alopecia areata.
American College of Cardiology
FEBRUARY 21, 2025
Patients with type 1 diabetes (T1D) were less likely to experience cardiovascular events when compared to patients with type 2 diabetes (T2D), according to a recent study published in the Journal of the Society for Cardiovascular Angiography & Interventions.
HCPLive
FEBRUARY 21, 2025
With this FDA approval, chenodiol tablets become the first approved drug to treat CTX, a rare lipid storage disease.
Circulation: Heart Failure
FEBRUARY 21, 2025
Circulation: Heart Failure, Ahead of Print.
HCPLive
FEBRUARY 21, 2025
The strategy detailed in the guidance aids the early identification of infants with biliary atresia and is intended for use between 2 and 4 weeks of life.
Circulation: Heart Failure
FEBRUARY 21, 2025
Circulation: Heart Failure, Ahead of Print.
HCPLive
FEBRUARY 21, 2025
Panelists discuss how key nonpharmacological interventions include vaccinations to prevent infections, pulmonary rehabilitation to improve function, and lung cancer screening for high-risk patients to enable early detection.
Circulation: Heart Failure
FEBRUARY 21, 2025
Circulation: Heart Failure, Ahead of Print.
HCPLive
FEBRUARY 21, 2025
Panelists discuss how chronic obstructive pulmonary disease (COPD) management is evolving with personalized therapies, nonpharmacological care, and advanced treatments. Early diagnosis, adherence, and innovation offer hope for improved outcomes and quality of life.
The American Journal of Cardiology
FEBRUARY 21, 2025
Publication date: Available online 20 February 2025 Source: The American Journal of Cardiology Author(s): Douglas Kyrouac, Nicholas Talbot, James MacNamara, Erin Howden, Michinari Hieda, Christopher Hearon, Tiffany Brazile, Benjamin Levine, Satyam Sarma
HCPLive
FEBRUARY 21, 2025
Furie discussed topline data from the REGENCY trial and key secondary endpoints.
The American Journal of Cardiology
FEBRUARY 21, 2025
Publication date: Available online 20 February 2025 Source: The American Journal of Cardiology Author(s): Joseph Mauch, Max Puthenpura, Pieter Martens, Timothy Engelman, Justin L Grodin, Matthew W. Segar, Ambarish Pandey, W.H.
HCPLive
FEBRUARY 21, 2025
These data suggest therapeutic modulation of IL-23 inhibitors for psoriasis in those who have shown stability may be a legitimate strategy to ensure efficacy and safety.
The American Journal of Cardiology
FEBRUARY 21, 2025
Publication date: Available online 20 February 2025 Source: The American Journal of Cardiology Author(s): Matthew S. Herzig, Ajar Kochar, James B. Hermiller, Rhian E. Davies, William J. Nicholson, Hibiki Orui, Eric. A.
Physiologically Speaking
FEBRUARY 21, 2025
Greetings! Welcome to the Physiology Friday newsletter. If you’re looking for a new (mess-free) way to fuel your workouts, you should check out Intra Chew—it’s a workout gummy that has carbohydrates and electrolytes. I’ve been using them during all of my long bike rides and before runs. You can get 20% off using the code BRADY20 on the site.
The American Journal of Cardiology
FEBRUARY 21, 2025
Publication date: Available online 21 February 2025 Source: The American Journal of Cardiology Author(s): Peter Zhang, Robert S. Zhang, Eugene Yuriditsky, Kevin Chen, Vincent Li, Lindsay Elbaum, Norma Keller, Allison A. Greco, Vikramjit Mukherjee, Radu Postelnicu, Kerry Hena, James M. Horowitz, Carlos L.
Ken Grauer, MD
FEBRUARY 21, 2025
The ECG in Figure-1 was obtained from a previously healthy middle-aged man who presented to the ED ( E mergency D epartment ) with new-onset CP ( C hest P ain ) that began ~1 hour earlier. QUESTION: The title I chose for todays Blog post is, This ECG tells a story. What is the Story that this initial ECG tells? Figure-1: The initial ECG in today's case obtained from a middle-aged man with CP. ( To improve visualization I've digitized the original ECG using PMcardio ).
CardiacWire
FEBRUARY 21, 2025
By Ravi Dhingra, MD, MPH, FACC, FAHA Sponsored By AstraZeneca Despite improving outcomes in patients with heart failure [1] , renin-angiotensin-aldosterone system inhibitor (RAASi) therapy is underutilized due to hyperkalemia (HK), often to the detriment of patients. [2] Ravi Dhingra, MD, MPH, FACC, FAHA An observational study [2] utilizing Optums de-identified Market Clarity Data from July 2019 to September 2021, evaluated the risk of progression to end-stage kidney disease (ESKD) and HF-relate
HCPLive
FEBRUARY 21, 2025
Patients with PBC and severe pruritus had worse HRQoL, greater rates of depression, and more sleep interference than those with mild/moderate pruritus.
All About Cardiovascular System and Disorders
FEBRUARY 21, 2025
Left Bundle Branch Block LBBB and STEMI Criteria: Start off with Cabrera’s sign and Chapmans sign. The post Left Bundle Branch Block LBBB and STEMI Criteria appeared first on All About Cardiovascular System and Disorders.
Journal of Cardiovascular Electrophysiology
FEBRUARY 21, 2025
ABSTRACT Background Exercise Oscillatory Ventilation (EOV) and a steep ventilatory efficiency (VE/VCO2) slope are features of ventilatory inefficiency on cardiopulmonary exercise testing (CPET), both associated with poor prognosis in patients with heart failure (HF). The prevalence in patients with co-existent atrial fibrillation (AF) and the impact of catheter ablation (CA) is unknown.
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