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Navigating the long road of Long COVID requires more than just recovery from an infection, it demands specialized, multifaceted care to address persistent and often invisible neurological symptoms.
A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival, in what a paper describing the results calls "an unprecedented recovery of cardiac function.
How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers are increasingly focusing on so-called organoids. These mini-organs, just a few millimeters in size, consist of groups of cells cultivated in the laboratory that can form organ-like structures.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
The following are key points to remember from a 2024 American College of Cardiology (ACC) expert consensus decision pathway (ECDP) on strategies and criteria for the diagnosis and management of myocarditis.
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Hypovolaemic phlebotomy reduced perioperative blood transfusion and improved operative conditions versus usual care in patients undergoing liver resection.
A State-of-the-Art review published in JACC: Cardiovascular Interventions covers the epidemiology, clinical implications, risk factors and preventive strategies for new-onset conduction disturbances (CDs) and the need for permanent pacemaker implantation (PPI) after TAVR, which the authors note are a limitation of this therapy.
These 52-week data highlight bimekizumabs efficacy in the scalp, nail, and genital region for psoriasis, along with Dermatology Life Quality Index (DLQI) improvements.
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Investigators looked at the effects of the exposome among patients with atopic dermatitis in order to better understand the influence of such elements as obesity and microorganisms.
How do N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-CTnI) predict long-term changes in cardiac structure and function in older adults?
The RESHAPE-HF2 (Randomized Investigation of the MitraClip Device in Heart Failure: Second Trial in Patients With Clinically Significant Functional Mitral Regurgitation) trial was an international, open-label, multicenter, randomized controlled trial designed to provide additional information regarding the safety and effectiveness of M-TEER in this patient population.
A 63-year-old woman presents to the office for a second opinion on chronic chest pain and heart failure management. She has a medical history of mixed connective tissue disease, obstructive sleep apnea, hepatic steatosis, and long-standing hypertension diagnosed in her twenties.
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Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft vasculopathy (CAV) leads to impaired myocardial blood flow (MBF), increasing the risk of cardiovascular death or retransplant among heart transplantation (HT) recipients. Data on elevation in donor-derived cell-free DNA (dd-cfDNA) and CAV in the absence of rejection are mixed. We sought to test the hypothesis that CAV with reduced MBF (RMBF) is associated with elevated dd-cfDNA.METHODS:A retrospective review was conducted o
Vivek Kaul, MD, discusses how primary care providers can effectively communicate the importance of colorectal cancer screening and guide patients in selecting the most suitable option, and the significant role of patient preferences and adherence in this decision-making process, while also addressing future innovations in screening methods.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BACKGROUNDMachine learning (ML) techniques are widely employed across various domains to achieve accurate predictions. This study assessed the effectiveness of ML in predicting early mortality risk among patients with acute intracerebral hemorrhage (ICH) in realworld settings.METHODS AND RESULTSMLbased models were developed to predict inhospital mortality in 527 patients with ICH using raw brain imaging data from
Vivek Kaul, MD, discusses how primary care providers can effectively communicate the importance of colorectal cancer screening and guide patients in selecting the most suitable option, and the significant role of patient preferences and adherence in this decision-making process, while also addressing future innovations in screening methods.
A fully automated algorithm to quantify aortic artery calcification (AAC) on computed tomography (CT) scans performed for other clinical purposes (opportunistic CT) can predict the risk for subsequent major adverse cardiovascular events (MACE), according to a study presented at the annual meeting of the Radiological Society of North America, held from Dec. 1 to 5 in Chicago.
Mayo explains current shortcomings of pruritus care in PBC and what the additions of elafibranor, seladelpar, and other agents in development may offer.
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ABSTRACT Management of patients with drug-induced type 1 Brugada pattern is complex and controversial. We report the case of a 66-year-old man affected by metastatic lung adenocarcinoma with type 1 Brugada phenocopy at electrocardiogram (ECG) after initiation of an oncological therapy with BRAF and MEK inhibitors.
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This case series shows that focal monopolar PFA is feasible and safe for SVC isolation, with temporary phrenic nerve and sinus node injuries resolving during the procedure ABSTRACT Introduction In patients with atrial arrhythmias originating from the superior vena cava (SVC), the use of radiofrequency energy to isolate the SVC is associated with a significant risk of injury both to the phrenic nerve and the sinus node.
Summary of the machine learning clustering methodology and results of the study. Clusters are identified using machine learning approach in the learning set population evaluating specific combinations of multiple characteristics. Then identified clusters are predicted and tested in the learning set to evaluate their association with outcomes. Finally, the reproducibility of the results of cluster analysis is tested in an external cohort (validation set).
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundRecent studies have suggested that increased brachialankle pulse wave velocity (baPWV) is a risk factor for diabetes. Exploring its relationship with insulin resistance is of interest, necessitating further studies across different sexes and age groups.Methods and ResultsThis cohort study involved 119 170 Korean adults with an average age of 39.8 years, none of whom had diabetes at baseline.
Written by Pendell Meyers An elderly female called EMS with acute chest pain. Her vitals were within normal limits, and here is her EMS ECG: What do you think? Sinus rhythm, and QRS shows likely subtle RBBB, plus LAFB. While some STE could be expected by the large wide S wave in inferior leads, there is is STE and possibly HATW in II, III, and AVF, with reciprocal findings in aVL.
Doppler echocardiography is best done with the ultrasound beam: A. Parallel to the direction of blood flow B. Perpendicular to the direction of blood flow C. At an angle of 45 degrees to the direction of blood flow D. At an angle of 135 degrees to the direction of blood flow Correct answer: A. Parallel to the direction of blood flow While two dimensional imaging gives better view if the structure being imaged is perpendicular to the beam direction, Doppler estimates the velocity of moving red bl
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