Tue.Jan 23, 2024

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Childhood relationships, experiences may have good and bad effects on adult heart health

American Heart News - Heart News

Research Highlights: Positive, warm relationships between caregiver and child were associated with higher odds of attaining ideal heart health at multiple points across a 20-year span of adulthood. Meanwhile, experiencing childhood adversity such as.

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Heart transplantation and biomarkers: a review about their usefulness in clinical practice

Frontiers in Cardiovascular Medicine

Advanced heart failure (AdvHF) can only be treated definitively by heart transplantation (HTx), yet problems such right ventricle dysfunction (RVD), rejection, cardiac allograft vasculopathy (CAV), and primary graft dysfunction (PGD) are linked to a poor prognosis. As a result, numerous biomarkers have been investigated in an effort to identify and prevent certain diseases sooner.

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Premature Mortality Gap Persists Among Patients with Gout

HCPLive

Mortality risks in gout have not improved in the United States in the past 3 decades, with a similar risk found among contemporary cases of gout in the United Kingdom.

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Algorithm for predicting valvular heart disease from heart sounds in an unselected cohort

Frontiers in Cardiovascular Medicine

Objective This study aims to assess the ability of state-of-the-art machine learning algorithms to detect valvular heart disease (VHD) from digital heart sound recordings in a general population that includes asymptomatic cases and intermediate stages of disease progression. Methods We trained a recurrent neural network to predict murmurs from heart sound audio using annotated recordings collected with digital stethoscopes from four auscultation positions in 2,124 participants from the Tromsø7 s

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascu

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Top 103 hospitals for cardiology, per Healthgrades

Becker's Hospital Review - Cardiology

Discover the top 103 hospitals nationwide for exceptional cardiology care, recognized by Healthgrades' "America's Best Hospitals" awards.

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Childhood Adversity May Increase Poor Heart Health Risk in Adulthood

HCPLive

Childhood trauma may decrease the likelihood of optimal heart health in adulthood, while stable and nurturing experiences are shown to promote heart health.

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More Trending

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Energy Drinks Linked to Poor Sleep Quality, Insomnia Among College Students

HCPLive

Male college students were found to consume more energy drinks than female college students, and they had a greater risk for a short sleep duration due to energy drink consumption.

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Dapagliflozin and Mode of Death in Heart Failure With Improved Ejection Fraction

JAMA Cardiology

This post hoc analysis of a randomized clinical trial evaluates the association of dapagliflozin with cause-specific deaths in patients with heart failure with improved ejection fraction.

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EM Quick Hits 54 Button Battery Ingestion, C. difficile, ECG in Tox, Bed Bugs, Fibrinogen in Trauma, Cold Air for Croup

ECG Cases

Olivia Ostrow on the management of button battery ingestions, Brit Long on C difficile infection, Jesse McLaren on an approach to ECG's in the tox patient, Joe Mullally on the identification and treatment of bed bug bites, Andrew Petrosoniak on fibrinogen replacement in bleeding trauma patients, Justin Morganstern on Cold Air for Croup. The post EM Quick Hits 54 Button Battery Ingestion, C. difficile, ECG in Tox, Bed Bugs, Fibrinogen in Trauma, Cold Air for Croup appeared first on Emergency Medi

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Sequana Medical Announces DSMB Approval to Start Randomized MOJAVE Cohort

DAIC

Getty Images milla1cf Tue, 01/23/2024 - 13:38 January 23, 2024 — Sequana Medical NV , a pioneer in the treatment of fluid overload in liver disease, heart failure and cancer, announced that an independent Data and Safety Monitoring Board (DSMB) approved the start of the randomized cohort in MOJAVE , the US Phase 1/2a study of DSR 2.0 for treatment of patients with diuretic-resistant heart failure , following review of the safety data reported from the non-randomized cohort.

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IgAN, Kidney Disease Common Among Patients with Inflammatory Bowel Disease

HCPLive

Findings from the retrospective cohort study suggest an increased prevalence of advanced kidney disease among individuals with Crohn disease and ulcerative colitis.

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AI Tool Predicts PCI Outcomes; Shellfish Blood Clotter; Persuasive CAC Scan Images

Med Page Today

(MedPage Today) -- Researchers developed the BMC2 artificial intelligence-based models for predicting death and complications after percutaneous coronary intervention (PCI). (European Heart Journal) A single bolus of recombinant staphylokinase.

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Beating the Odds: Inside the Tribe with a Near-Zero Rate of Heart Disease.

Dr. Paddy Barrett

Cardiovascular disease is the leading cause of death worldwide. It kills almost twice as many people globally when compared to all cancers combined. Over 80% of early heart disease is preventable. However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score.

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What kind of AV block is this? And why does she develop Ventricular Tachycardia?

Dr. Smith's ECG Blog

This was written by Magnus Nossen The patient is a female in her 50s. She presented with a one week hx of «dizziness» and weakness. She was feeling fine prior to the last seven days. There was no chest pain. She did admit to shortness of breath on exertion. She had no known heart condition. Other than being overweight and having an elevated cholesterol she was healthy.

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Combination Therapy for AD

HCPLive

Physician assistant Andera Nguyen shares her experience on combination therapy and class switching.

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APOE genetic variants linked to Alzheimer's disease also associated with the development of subclinical atherosclerosis

Medical Xpress - Cardiology

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid have found that one of the most potent genetic risk factors for Alzheimer's disease, apolipoprotein E4 (APOE4), is also associated with an increased risk of developing subclinical atherosclerosis in middle age. The study also demonstrates protection against subclinical atherosclerosis in people carrying the variant APOE2, which protects against Alzheimer's disease.

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Fatigue as hallmark of Fabry disease: role of bioenergetic alterations

Frontiers in Cardiovascular Medicine

Fabry disease (FD) is a lysosomal storage disorder due to the impaired activity of the α -galactosidase A (GLA) enzyme which induces Gb3 deposition and multiorgan dysfunction. Exercise intolerance and fatigue are frequent and early findings in FD patients, representing a self-standing clinical phenotype with a significant impact on the patient's quality of life.

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FDA Expands Bupivacaine and Meloxicam (Zynrelef) Approval to Include Additional Orthopedic and Soft Tissue Procedures

HCPLive

On January 23, 2024, Heron Therapeutics announced the FDA had approved its sNDA for bupivacaine and meloxicam extended-release solution to expand the indication to include soft tissue and orthopedic surgical procedures, including procedures in which direct exposure to articular cartilage is avoided.

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Current Mouse Models of Intracranial Aneurysms: Analysis of Pharmacological Agents Used to Induce Aneurysms and Their Impact on Translational Research

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. Intracranial aneurysms (IAs) are rare vascular lesions that are more frequently found in women. The pathophysiology behind the formation and growth of IAs is complex. Hence, to date, no single pharmacological option exists to treat them. Animal models, especially mouse models, represent a valuable tool to explore such complex scientific questions.

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Association of sleep characteristics with cardiovascular disease risk in adults over 40 years of age: a cross-sectional survey

Frontiers in Cardiovascular Medicine

Background The relationship between sleep characteristics and cardiovascular disease (CVD) risk has yet to reach a consistent conclusion, and more research needs to be carried out. This study aimed to explore the relationship between snoring, daytime sleepiness, bedtime, sleep duration, and high-risk sleep patterns with CVD risk. Methods Data from the National Health and Nutrition Examination Survey (NHANES) 2015–2018 were collected and analyzed.

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Enrolling Older Adults in Revascularization Trials: Complete or Culprit-Only PCI in Older Patients With Myocardial Infarction (The FIRE Trial)

American College of Cardiology

Both the COMPLETE and PRAMI trial findings supported the benefits of complete revascularization over culprit-only percutaneous coronary intervention (PCI) in patients presenting with myocardial infarction (MI) and multivessel coronary artery disease.

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Standardized risk-stratified cardiac assessment and early posttransplant cardiovascular complications in kidney transplant recipients

Frontiers in Cardiovascular Medicine

Introduction Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in kidney transplant recipient (KTR). There is a dearth of standardized guidelines on optimal cardiovascular evaluation of transplant candidates. Methods This single-center cohort study aims to determine the effectiveness of our standardized risk-stratified pretransplant cardiovascular screening protocol, which includes coronary angiography (CAG), in identifying advanced CVD, the proper pretransplant manage

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Researchers develop new technology for monitoring atrial fibrillation

Medical Xpress - Cardiology

Researchers from two Lithuanian universities have developed a patient-safe monitoring technology to identify and manage individual factors provoking atrial fibrillation. The technology is a result of a collaboration between Kaunas University of Technology Biomedical Engineering Institute (KTU BMEI) and Vilnius University (VU) Santaros Clinics.

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Circulating ketone bodies and mortality in heart failure: a community cohort study

Frontiers in Cardiovascular Medicine

Background The relationship between ketone bodies (KB) and mortality in patients with heart failure (HF) syndrome has not been well established. Objectives The aim of this study is to assess the distribution of KB in HF, identify clinical correlates, and examine the associations between plasma KB and all-cause mortality in a population-based HF cohort.

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Clinician Quiz: Hepatitis C Treatment Recommendation Updates

HCPLive

Test your knowledge with this clinician quiz! In this quiz, we test your knowledge of updates in the management of hepatitis C virus based on the AASLD/IDSA 2023 guidance update.

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MRI pattern characterization of cerebral cardioembolic lesions following atrial fibrillation ablation

Frontiers in Cardiovascular Medicine

Background Recognizing etiology is essential for treatment and secondary prevention of cerebral ischemic events. A magnetic resonance imaging (MRI) pattern suggestive of an embolic etiology has been described but, to date, there are no uniformly accepted criteria. Aim The purpose of the study is to describe MRI features of ischemic cerebral lesions occurring after transcatheter ablation of atrial fibrillation (AF).

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Wesley Mizutani, MD: SB 496 Expands Insurance Coverage for Biomarkers

HCPLive

Wesley Mizutani, MD, discusses California's SB 496 legislation, which addresses the crucial role of biomarkers in guiding optimal drug selection to improve overall healthcare outcomes.

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Rethinking heart failure clinical trials: the heart failure collaboratory

Frontiers in Cardiovascular Medicine

The Heart Failure Collaboratory (HFC) is a consortium of stakeholders in the heart failure (HF) community that aims to improve the infrastructure of clinical research to promote development of novel therapies for patients. Since its launch in 2018, HFC has implemented several solutions to tackle obstacles in HF clinical research including training programs to increase the number of clinicians skilled in conducting clinical trials, novel study designs, and advocacy for a diverse and inclusive HF

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8 heart centers opening, expanding in 2024

Becker's Hospital Review - Cardiology

Discover the latest developments in heart care as eight centers across the country open, expand, or upgrade their facilities and services this year.

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Heart–brain interaction in cardiogenic dementia: pathophysiology and therapeutic potential

Frontiers in Cardiovascular Medicine

Diagnosis and treatment of patients with cardiovascular and neurologic diseases primarily focus on the heart and brain, respectively. An increasing number of preclinical and clinical studies have confirmed a causal relationship between heart and brain diseases. Cardiogenic dementia is a cognitive impairment caused by heart dysfunction and has received increasing research attention.

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Novel Frailty Scale Predicts Adverse Events in Patients Undergoing LAAO

American College of Cardiology

A novel frailty scale was found to accurately predict adverse events in patients undergoing percutaneous left atrial appendage occlusion (LAAO), with patients classified as frail at greater risk of in-hospital complications and 45-day mortality, according to a study published in the Journal of Interventional Cardiac Electrophysiology.

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Case Report: A myxoma with a far reach

Frontiers in Cardiovascular Medicine

A 73-year-old woman presented to the emergency department with a syncopal episode and a history of dizzy spells. A transthoracic echocardiogram demonstrated a large left atrial mass extending into the right upper pulmonary veins. Subsequently, cardiac magnetic resonance imaging and coronary computed tomography angiography with three-dimensional reconstruction and printing of the heart and mass were performed, which demonstrated a high index of suspicion for an atypical left atrial myxoma.

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The impact of two radical sternectomy surgical techniques on the outcome of deep sternal wound infections

Journal of Cardiothoracic Surgery

Deep sternal wound infection (DSWI) is a rare, yet devastating complication after cardiac surgery. While the surgical treatment always implies the soft tissue and bone debridement, there is little data about t.

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Gujarat’s 2023 Cardiac Crisis! EMRI got 1 call every 7.5 mins

Wellnest

In 2023, Gujarat grappled with a cardiac crisis, as reported by the Emergency Management and Research Institute (EMRI) 108, with a staggering 72,573 cases. This marked a significant 35% increase from 2018, signaling a pressing need for comprehensive strategies to address the concerning trend. The state recorded a 29% annual rise compared to 2022, underlining the urgency for effective preventive measures.

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Achieving SVR Reduces Risk of Cardiovascular Events in Patients with HCV

HCPLive

Results highlight the benefit of achieving sustained virological response with DAAs for decreasing patients’ risk of carotid atherosclerosis and peripheral artery disease, especially among those with severe fibrosis.

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Young ICU Nurse’s Journey from Murmur Discovery to Heart Surgery

CTVS

35-year-old Tamara Fort is an ICU nurse and what many would consider the epitome of good health. She lifts weights three to four times a week and watches her nutrition closely. She isn’t someone you would consider to be at risk for heart disease. But for the past two years, she experienced shortness of breath, and knew something wasn’t quite right.

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