Sun.Feb 09, 2025

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Brain Bleed Survivors Walk a Razor-Thin Line Taking DOACs

Med Page Today

(MedPage Today) -- LOS ANGELES -- In the PRESTIGE-AF trial, survivors of intracerebral hemorrhage (ICH) had good protection against future ischemic events using direct oral anticoagulants (DOACs) -- though, as feared, bleeding side effects.

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The HCPFive: Top News for Healthcare Providers from the Week of 02/02

HCPLive

Our top 5 headlines include a trial of gene-edited pig kidneys, a first-of-its-kind antibiotic approval, and new guidelines for migraine.

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Major Adverse Cardiovascular Events 1 Year After Discharge in Out-of-Hospital Cardiac Arrest Survivors

Circulation

Circulation, Volume 151, Issue 6 , Page 421-423, February 11, 2025.

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Secondary Prevention Medications for CVD Underutilized in Global Analysis

HCPLive

Use of medications for secondary CVD prevention is low globally, and in most country income-level groups, with no indication of improvement.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Remuscularizing the failing heart in primates

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 10 February 2025; doi:10.1038/s41569-025-01136-z Tissue engineered heart muscle implanted on to the epicardium can structurally and functionally remuscularize the failing hearts of rhesus macaques, with no major adverse effects; a clinical trial of this approach is now underway in patients with heart failure.

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DECT Scans Unable to Detect Gout Nephropathy

HCPLive

Dual-energy computed tomography is able to characterize MSU in joints as well as chronic asymptomatic urolithiasis in kidneys.

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More Trending

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Cox Regression Model in Clinical Research: Overview of Key Properties and Interpretation

Circulation

Circulation, Volume 151, Issue 6 , Page 337-339, February 11, 2025.

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Which common medicine won a place in the Guinness Book of World Records?

Heart Sisters

It’s been in use for thousands of years.

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Lipoprotein(a) as a Pharmacological Target: Premises, Promises, and Prospects

Circulation

Circulation, Volume 151, Issue 6 , Page 400-415, February 11, 2025. Atherosclerotic cardiovascular disease is a major health concern worldwide and requires effective preventive measures. Lp(a) (lipoprotein [a]) has recently garnered attention as an independent risk factor for astherosclerotic cardiovascular disease, with proinflammatory and prothrombotic mechanisms contributing to its atherogenicity.

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Peripheral Venous Pressure-Guided Decongestion: A New Approach Yet to Prove Beneficial

The American Journal of Cardiology

Publication date: Available online 8 February 2025 Source: The American Journal of Cardiology Author(s): Timir K Paul

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Antagonizing HFpEF by Targeting Fibrosis

Circulation

Circulation, Volume 151, Issue 6 , Page 396-399, February 11, 2025.

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From the Literature

Circulation

Circulation, Volume 151, Issue 6 , Page 416-417, February 11, 2025.

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Response by Shen et al to Letter Regarding Article, “Effect of Sacubitril/Valsartan on Cognitive Function in Patients With Heart Failure With Preserved Ejection Fraction: A Prespecified Analysis of PARAGON-HF”

Circulation

Circulation, Volume 151, Issue 6 , Page e38-e38, February 11, 2025.

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Letter by Tunçez and Gürses Regarding Article, “Effect of Sacubitril/Valsartan on Cognitive Function in Patients With Heart Failure With Preserved Ejection Fraction: A Prespecified Analysis of PARAGON-HF”

Circulation

Circulation, Volume 151, Issue 6 , Page e37-e37, February 11, 2025.