Wed.Oct 30, 2024

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Study: Low-level lead poisoning accounts for cognitive deficits in children, risk factors for heart conditions

Medical Xpress - Cardiology

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, according to a paper by Columbia University Mailman School of Public Health, Simon Fraser University in Canada, and Harvard Medical School, and Boston Children's Hospital.

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ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients

Med Page Today

(MedPage Today) -- Most patients should not stop taking GLP-1 receptor agonists prior to elective surgery, according to updated guidance from several medical societies, including the American Society of Anesthesiologists (ASA). This recommendation.

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Standing desks are not the answer to decreasing blood pressure, clinical trial shows

Medical Xpress - Cardiology

Alternating between sitting and standing at work decreases sedentary behavior, but it has no effect on lowering blood pressure, according to a study led by a West Virginia University epidemiologist. Researchers also found that too much standing during work may have negative effects on cardiovascular health.

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Researchers identify 'sweet spot' for safe surgery after heart attack

Science Daily - Heart Disease

New research suggests older adults wait 3-6 months after a heart attack before elective noncardiac surgery to reduce the risk of serious complications like stroke or another heart attack.

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Heart signals brain to boost sleep for healing after heart attack, study finds

Medical Xpress - Cardiology

A heart attack can trigger a desire to get more sleep, allowing the heart to heal and reduce inflammation—and this happens because the heart sends special signals to the brain, according to a new Mount Sinai study.

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50 top hospitals for vascular surgery: Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those recipients, 50 hospitals were recognized for delivering superior clinical outcomes in vascular surgery.

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Low-level lead poisoning is still pervasive in the US and globally

Science Daily - Heart Disease

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.

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Prior Authorization Managers, Care Management Homes Could Expedite IBD Care

HCPLive

A retrospective review of a community-based practice provides insights into navigating setbacks in IBD care initiation due to insurance requirements.

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Weight Loss After Bariatric Surgery in Teens Persisted at 10 Years

Med Page Today

(MedPage Today) -- For adolescents, weight loss after bariatric surgery was durable out to 10 years, data from the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study confirmed. Among 260 adolescents who underwent bariatric surgery.

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ASN: hypertension most common cardiovascular comorbidity seen with dialysis

Medical Xpress - Cardiology

Hypertension is the most common cardiovascular disease (CVD) comorbidity seen among dialysis patients globally, according to a study presented at Kidney Week, the annual meeting of the American Society of Nephrology, held from Oct. 23 to 27 in San Diego.

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Violeta Popov, MD, PhD: Do GLP-1 RAs Need to Be Held Before Endoscopy?

HCPLive

Popov reviews findings from her late-breaking presentation at ACG 2024 suggesting GLP-1 RAs may not need to be held prior to upper endoscopy.

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Database analysis identifies 'sweet spot' for safe surgery after heart attack

Medical Xpress - Cardiology

After a heart attack, aging adults face double or triple the risk of life-threatening complications—like a debilitating stroke or another heart attack—when they move forward with elective noncardiac surgeries too soon, according to new University of Rochester research published in JAMA Surgery.

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Evan Dellon, MD, MPH: “Promising” Phase 3 Cendakimab Data for Eosinophilic Esophagitis

HCPLive

Dellon reviews phase 3 data supporting the 48-week safety and efficacy of cendakimab for treating EoE.

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Case 34-2024: A 69-Year-Old Man with Dyspnea after Old Myocardial Infarction

The New England Journal of Medicine

A 69-year-old man with a history of MI and cardiomyopathy presented with 2 days of dyspnea. Regular tachycardia (124 beats per min), diaphoresis, and rales were present. A diagnosis was made.

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Precision robotics offers hope for heart disease treatment

Science Daily - Heart Disease

The advanced drug testing system screens multiple potential therapies simultaneously in beating heart cells.

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The Way to a Patient’s Heart — Vascular Access in Cardiac Arrest

The New England Journal of Medicine

Every year, thousands of lives are saved with cardiopulmonary resuscitation (CPR). Yet, overall survival among patients with out-of-hospital cardiac arrest is approximately 10%, even in well-performing emergency medical systems. The interventions that are undertaken at the scene of a cardiac arrest are the most likely interventions to improve outcomes: early.

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The 40 Best Cardiology Newsletters, Websites, and Influencers to Follow in 2024

CardiacWire

We’re dedicating today’s top story to the people and publications that we rely on to find the most interesting cardiology stories from across the web. Assuming that you already subscribe to Cardiac Wire , these are the 40 other newsletters, websites, and social media stars to follow if you want to keep up with the latest and greatest in cardiology. I’ll always check the mainstream cardiology news websites ( TCTMD , Medscape , et al.) and the major cardiovascular journals ( JACC , AHA , JAMA Card

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Judge dismisses IU Health antitrust lawsuit

Becker's Hospital Review - Cardiology

A federal court has dismissed an antitrust lawsuit filed against Indianapolis based-Indiana University Health. The lawsuit was filed by vascular surgeon Ricardo Vasquez, MD, who alleged the health system engaged in anti-competitive behavior.

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Kishore Iyer, MD, MBBS: STARS Subgroup Analyses for Apraglutide in SBS-IF

HCPLive

Iyer reviews findings from subgroup analyses of the phase 3 STARS study of apraglutide for SBS-IF based on demographics and disease characteristics.

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TCT Abstracts Use NCDR Data to Evaluate Site Volume and Failure to Rescue, Impact of CAD and Revascularization, More

American College of Cardiology

Several abstracts presented at TCT 2024, taking place Oct. 27-30 in Washington, DC, used data from ACC’s CathPCI Registry, Chest Pain – MI Registry and the STS/ACC TVT Registry to evaluate institutional volume and failure to rescue in TAVR, outcomes of sequential TAVR and mitral transcatheter edge-to-edge repair (TEER), the impact of coronary artery disease (CAD) and revascularization on health status and more.

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10-Year Follow-Up Shows Lasting Benefits of Bariatric Surgery for Teens with Severe Obesity

HCPLive

A decade after bariatric surgery, most teens maintained weight loss and reduced obesity-related conditions such as type 2 diabetes and hypertension.

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Routine colchicine administration after acute myocardial infarction does not improve outcomes

Medical Xpress - Cardiology

The largest trial to examine the impact of colchicine in acute myocardial infarction (MI) found that both acute and long-term colchicine use did not reduce cardiovascular death, myocardial infarction, stroke, or ischemia-driven revascularization.

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Study Confirms Positive Long-Term Outcomes Using AI-enabled FFRCT and Plaque Analysis

DAIC

Data confirm the use of FFR CT and Plaque Analysis helps assess long-term risks, informing more personalized and effective treatment plans for patients with coronary artery disease. tim.hodson Wed, 10/30/2024 - 11:23 Oct. 27, 2024 — HeartFlow, Inc. recently announced seven-year data confirming the use of HeartFlow’s AI-enabled fractional flow reserve computed tomography (FFR CT ) and Plaque Analysis in the assessment of long-term risk of coronary artery disease (CAD) in clinically stable, symp

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Small but important differences seen between rosuvastatin, atorvastatin

Medical Xpress - Cardiology

There are small but important differences in risk for some clinical outcomes associated with rosuvastatin and atorvastatin, according to a study published online Oct. 29 in Annals of Internal Medicine.

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Minimally Invasive Vascular Disease Treatments

CTVS

Research shows that in recent years almost half of all adults in the United States have been living with heart disease, one of the most prominent forms of vascular disease. Vascular disease affects the body’s vast network of blood vessels, veins and arteries.

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Research shows new method helps doctors safely remove dangerous heart infections without surgery

Medical Xpress - Cardiology

Doctors at Mayo Clinic have used a new catheter-based approach to draw out resistant pockets of infection that settle in the heart, known as right-sided infective endocarditis, without surgery. Unless treated quickly, the walled-off infections can grow, severely damaging heart valves and potentially affecting other organs as well. In a recent study, over 90% of the participants had their infection cleared, and they had lower in-hospital mortality compared to those whose infections remained.

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ADORING Trial Open-Label Extension: Tapinarof Cream 1% Results in Atopic Dermatitis

HCPLive

This interview at the Fall Clinical Dermatology Conference features a discussion with Stein Gold regarding the open-label extension of the phase 3 ADORING trial regarding tapinarof.

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Large-bore mechanical thrombectomy yields better outcomes for intermediate-risk pulmonary embolism

Medical Xpress - Cardiology

Findings from the first international randomized controlled trial to compare patient outcomes following treatment with large-bore mechanical thrombectomy (LBMT) versus catheter-directed thrombolysis (CDT) for intermediate-risk pulmonary embolism (PE) show that LBMT is superior with respect to the hierarchically-tested aggregated outcome of all-cause mortality, intracranial hemorrhage, major bleeding, clinical deterioration and/or escalation to bailout therapy, and postprocedural ICU admission an

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MASH and Cardiometabolic Health: Practical Treatments for Managing Complex Patients (Part 1) 

Cardiometabolic Health Congress

November is National Diabetes Month , and with the increasing overlap between type 2 diabetes (T2D) and metabolic dysfunction-associated steatohepatitis (MASH) , it’s critical to focus on integrating liver health into the management of cardiometabolic patients. This two-part series breaks down key treatment approaches for MASH, helping healthcare providers stay informed and deliver evidence-based care.

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Cardiac remodelling in patients with atrial fibrillation and obstructive sleep apnoea

Open Heart

Background Obstructive sleep apnoea (OSA) can cause left atrial (LA) and left ventricular (LV) remodelling, which is linked to atrial fibrillation (AF). Whether continuous positive airway pressure (CPAP) can reverse LA and LV remodelling in patients with OSA and paroxysmal AF (PAF) has yet to be studied. We assessed the impact of CPAP treatment on LA and LV size and function in patients with OSA and PAF before and after catheter ablation.

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Seladelpar Efficacious for Patients with PBC and Compensated Cirrhosis

HCPLive

Open-label, interim data from ASSURE shows positive effect and tolerability with once-daily seladelpar in patients with primary biliary cholangitis and compensated cirrhosis.

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Precision robotics offers hope for heart disease treatment in young adults

Medical Xpress - Cardiology

An advanced robotic system at The Hospital for Sick Children (SickKids) is changing the way physicians and scientists approach treatments for heart disease.

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Ladan Zand, MD: Evaluating Obinutuzumab in Primary FSGS and Further Research

HCPLive

Zand discussed the unmet need for refractory primary FSGS and the importance of investigations specifically in this population.

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ACURATE neo2 vs. Approved TAVR Devices in All-Risk Patients With Severe AS

American College of Cardiology

The goal of the ACURATE IDE trial was to evaluate the Acurate neo2 self-expanding valve compared with a commercially available valve (Sapien or Evolut) among patients with aortic stenosis across the risk spectrum.

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Therapeutic Inertia in Atopic Dermatitis Persists, Impacts Patient Outcomes

HCPLive

Many with moderate-to-severe atopic dermatitis do not reach treatment targets in 12 months, underscoring a need for proactive management strategies.

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FLASH: AI-Based Quantitative Angiography Shows Promise For Assisting PCI

American College of Cardiology

Results from the FLASH trial demonstrate the noninferiority of artificial intelligence-based fully automated quantitative coronary angiography (AI-QCA)-assisted PCI compared with optical coherence tomography (OCT)-guided PCI in achieving optimal minimal stent area, with comparable procedural complications, OCT-defined endpoints, and six-month clinical outcomes, according to researchers presenting the findings at TCT 2024.

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Long-term Options for IgAN Management, with Jonathan Barratt, MD, PhD

HCPLive

In this segment, Barratt reflects on recent updates in the management of IgA nephropathy, particularly data on long-term use of Nefecon.

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