Fri.Oct 04, 2024

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FDA Approves Exact Sciences’ Cologuard Plus Test for Colorectal Cancer Screening

HCPLive

The approval is based on findings from BLUE-C, where Cologuard Plus demonstrated sensitivities of 95% for colorectal cancer and 43% for advanced precancerous lesions at 94% specificity.

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New therapeutic target for cardiac arrhythmias emerges

Science Daily - Heart Disease

Researchers identified a lipid that is involved in regulating cardiac ion channels, providing insights into possible mechanisms of cardiac arrhythmias in heart failure and a potential pathway for future therapeutic development.

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5 FDA Decisions to Watch in Q4 2024

HCPLive

A review of 5 highly anticipated FDA decisions expected by year-end, including acoramidis for ATTR-CM, olezarsen for FCS, sotagliflozin for T1D and CKD, and more.

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Timeline of Irregular Heartbeats Emerges From Close Watch of Young Binge Drinkers

Med Page Today

(MedPage Today) -- Continuous rhythm monitoring showed the timeline in which heart rate and atrial tachycardias typically arise after binge drinking by young adults, researchers reported. In people with no known history of cardiac arrhythmias.

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Hidradenitis Suppurativa Does Not Increase Female Infertility Risk, Study Finds

HCPLive

Contrary to previous research, findings suggest no significant difference in infertility between patients with HS, other dermatological diseases, and healthy controls.

Research 105
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Study finds high endocarditis mortality rates for those who inject drugs, but treatment dramatically improves survival

Medical Xpress - Cardiology

People who inject drugs are dying at an alarming rate from endocarditis, a serious but treatable heart-valve infection. But their odds of survival improve dramatically, even five years after their first admission to hospital, if they're treated not just for heart infection but are also provided with addiction support while in hospital, a Canadian study shows.

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Matched Analysis Finds No Link Between Dupilumab Use and Adverse Pregnancy Outcomes

HCPLive

An EADV 2024 study suggests dupilumab use during pregnancy is generally safe and may lower risks of preterm labor, gestational hypertension, and diabetes.

More Trending

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HCPLive Five at Maui Derm NP+PA Fall 2024

HCPLive

Counting down the most impactful news at major medical meetings, it’s the HCPLive Five! This episode focuses on 5 key updates from Maui Derm NP+PA Fall 2024 in Nashville.

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Why women are still being underdiagnosed with heart disease

Medical Xpress - Cardiology

Women in the UK continue to be underdiagnosed and under-treated for cardiovascular diseases, a recent statement from the British Cardiovascular Societies has concluded. While there are many reasons for this, part of the problem is that cardiovascular disease is still seen as a "man's condition.

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Secukinumab Surpasses Ustekinumab in Clearing Skin for Generalized Pustular Psoriasis

HCPLive

A study shows secukinumab clears skin lesions faster than ustekinumab in generalized pustular psoriasis, with improved responses observed by week 2.

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Study Finds AI Can Help Predict Patients With High Risk of Major Adverse Cardiac Events

DAIC

tim.hodson Fri, 10/04/2024 - 11:39 Oct. 2, 2024 — Eko Health recently announced a new independent study from researchers at Imperial College London (Imperial) that demonstrated how AI can identify patients with significantly higher risk of experiencing major adverse cardiac events (MACE), including heart attacks and heart failure. Researchers used Eko Health's FDA-cleared and UKCA-marked Low Ejection Fraction AI to conduct the study, which reinforced the power of Eko's AI for early detection whi

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Adherence to Phototherapy for Psoriasis Influenced by Patient Variables

HCPLive

A small percentage of participants with psoriasis reported adequate adherence, with nearly half showing low adherence to phototherapy treatment.

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CV Events Following COVID-19 Vaccination

American College of Cardiology

What are the risks of several cardiovascular (CV) and cerebrovascular events following coronavirus disease 2019 (COVID-19) vaccination in a Swedish nationwide register-based cohort?

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Alcohol Use, Smoking Tobacco May Negatively Impact Psoriasis Treatment Efficacy

HCPLive

Study findings highlight the individual and combined impact of smoking tobacco and drinking alcohol on achieving PASI75 after 8 weeks of treatment.

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Leveraging AI to analyze retinal images for cardiovascular risk assessment

Medical Xpress - Cardiology

A recent position paper in the Asia-Pacific Journal of Ophthalmology explores the transformative potential of artificial intelligence (AI) in ophthalmology.

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Early Antibiotic Treatment Associated With Atopic Dermatitis, Asthma

HCPLive

Further research is needed to understand the mechanism behind the link as antibiotic exposure is often necessary in care.

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Breast Cancer and CV Health: Key Points

American College of Cardiology

The following are key points to remember from a review about breast cancer and cardiovascular (CV) health.

Cancer 64
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Twice-Daily ESK-001 Treatment for Psoriasis Leads to Majority Achieving PASI 75

HCPLive

These 28-week data on twice-daily ESK-001 highlight the drug’s safety and efficacy among patients with psoriasis.

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ACC Practice Made Perfect: Building Blocks: Strategies for Cardiovascular Service Line Development

American College of Cardiology

Welcome to the Cardiovascular (CV) Dyad Leadership Strategic Planning Series! In episode one of four, Dr. Jeff Carstens discusses with Drs. Tom Draper and Michael Montgomery steps to developing a strategic plan for the CV service line.

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Crisugabalin Provides Significant Pain Improvements in Adults with Postherpetic Neuralgia

HCPLive

Crisugabalin at 40 mg/d or 80 mg/d significantly reduced daily pain in adults with postherpetic neuralgia, a phase 3 study found.

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Clinical and Imaging Diagnostic Criteria for Myocarditis

American College of Cardiology

What is the comparative predictive value of ESC criteria for clinically suspected myocarditis, updated Lake-Louise criteria (LLC), AHA criteria for probable acute myocarditis (pAM), and expert consensus criteria for acute myocarditis (AM) and complicated myocarditis (CM)?

Article 40
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Dupilumab Improves Sleep, Itch, and Other QoL Measures in Children With Eczema

HCPLive

A new post-hoc analysis has also revealed improvements in quality of life in patients’ caregivers.

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An evidence less quote about EBM

Dr. S. Venkatesan MD

Visit the post for more.

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Unlocking the Mystery at AHN Autoimmunity Institute

HCPLive

AHN Autoimmunity Institute Launches Nationwide Biobank to Advance Relapsing Polychondritis Research and Treatments

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Physiology Friday #238: 'Weekend Warriors' Get the Same Health Benefits as Regular Exercisers

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Exercise 103
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One-day Decompression at Allegheny Health Network

HCPLive

AHN’s minimally invasive spine surgery relieves patients’ pain and quickly gets them back to living.

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ECG Blog #450 — A "Healthy" 30yo with Dizziness

Ken Grauer, MD

The ECG shown in Figure-1 was obtained from a previously healthy 30-year old man — who had this ECG as part of a "routine" pre-employment physical exam. He has had a few episodes of "dizziness" , but no syncope. He is otherwise well without medical problems. QUESTIONS: How would YOU interpret the ECG in Figure-1 ? How to evaluate this patient? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ) MY Thoughts on the ECG in Figure-

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