Mon.Apr 08, 2024

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10 FDA panel members who voted on heart device connected to Abbott: Report

Becker's Hospital Review - Cardiology

The FDA convened a committee of advisers to assess a cardiac device made by Abbott, but the agency did not disclose that 10 of the 14 members had received payments from the company or conducted research it had funded, KFF Health News reported April 8.

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Study Suggests Most Patients with Acute Coronary Syndromes Can Safely Stop Aspirin One Month After Percutaneous Coronary Intervention

DAIC

milla1cf Mon, 04/08/2024 - 17:57 April 8, 2024 — People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study prese

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Early Win for Preemptive Stents on Vulnerable Coronary Plaque

Med Page Today

(MedPage Today) -- ATLANTA -- The concept of using stents to seal off non-flow-limiting vulnerable plaques, before they have a chance to rupture, worked out in the first major trial testing this provocative idea. Compared with standard medical.

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Unnecessary use of beta-blockers after a heart attack?

Science Daily - Heart Disease

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily, new study suggests.

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Self-Selection for Statin Appears Safe, Effective

Med Page Today

(MedPage Today) -- ATLANTA -- The vast majority of people correctly identified their own need for a statin using a web tool and took the drug appropriately without a prescription, according to an actual use study, supporting the safety of approval.

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Heart disease, depression linked by inflammation

Science Daily - Heart Disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers have found.

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Electronic sock detects unhealthy walking style linked to cardiovascular and diabetic complications

Medical Xpress - ECG

An electronic sock that detects an unhealthy walking style linked with diabetes and poor circulation shows promise for preventing foot ulcers and amputation. The novel research is set to benefit the many patients with diabetes who have clogged arteries in the legs and is presented for the first time at EHRA 2024.

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Preventive angioplasty does not improve prognosis

Science Daily - Heart Disease

For heart attack patients, treating only the coronary artery that caused the infarction works just as well as preventive balloon dilation of the other coronary arteries, according to a new large study.

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Alternate-Day Iron May Be More Effective for Patients with Anemia, Diabetes

HCPLive

Oral iron supplements did not significantly differ in increasing hemoglobin and ferritin levels, but the every-other-day oral iron proved more effective than daily use.

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A pulse of innovation: AI at the service of heart research

Science Daily - Heart Disease

Researchers unveiled BeatProfiler, a groundbreaking new tool -- a comprehensive software that automates the analysis of heart cell function from video data. It's the first system to integrate the analysis of different heart function indicators, such as contractility, calcium handling, and force output into one tool, speeding up the process significantly and reducing the chance for errors.

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Botulism After 'Botox'? NEJM Ignored Nazi Atrocities; Jungle Jack's Alzheimer's

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. The Tennessee Department of Health said it's collaborating with the CDC and FDA to investigate botulism-like symptoms in people who received Botox-like botulinum.

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Preventive Coronary Intervention on Stenosis With Functionally Insignificant Vulnerable Plaque

American College of Cardiology

The goal of the PREVENT trial was to compare the safety and efficacy of medical therapy along with focal preventive PCI of non-flow-limiting vulnerable plaque compared with medical therapy alone.

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Beta-Blockers Fail to Deliver Secondary Prevention Benefit in Key MI Patients

Med Page Today

(MedPage Today) -- ATLANTA -- Beta-blockers had no additive benefit over contemporary therapies for people with acute myocardial infarction (MI) maintaining a preserved left ventricular ejection fraction (LVEF), the REDUCE-AMI randomized trial.

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Regional Differences in the Outcomes of Catheter Ablation for Atrial Fibrillation in the United States

HeartRhythm

There is insufficient data assessing the regional differences in catheter ablation outcomes for atrial fibrillation (AF) in the United States. We examined such variations by analyzing procedural complications and in-hospital outcomes among patients undergoing AF ablation utilizing the National Inpatient Sample (NIS), a collaborative effort between federal, state, and industry stakeholders sponsored by the Agency for Healthcare Research and Quality (AHRQ), captures hospital data from over 7 milli

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Chelation Flops for Cardio Health After Heart Attack

Med Page Today

(MedPage Today) -- ATLANTA -- Chelation to remove lead and other heavy metals didn't improve outcomes for type 2 diabetes patients after myocardial infarction (MI), the TACT2 trial showed. Cumulative incidence of time to first event (MI, stroke.

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PREVENT: Preventive PCI Superior to Optimal Medical Therapy Alone to Reduce Cardiac Events From Vulnerable Plaques

American College of Cardiology

PCI performed preventively in patients with high-risk vulnerable plaques was found to be superior to optimal medical therapy alone in preventing a serious cardiac event, according to the results of the PREVENT trial, the largest study on preventive PCI to date, presented during a Late-Breaking Clinical Trial session during ACC.24 in Atlanta and published simultaneously in The Lancet.

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Self-Expanding Evolut Valves Edge Out Sapien in Majority-Female TAVR Trial

Med Page Today

(MedPage Today) -- ATLANTA -- For transcatheter aortic valve replacement (TAVR) candidates with a small aortic annulus, the two leading platforms offered differing hemodynamic valve performances despite being similarly effective at 1 year, according.

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Ninerafaxstat Shows Promise in Phase 2 IMPROVE-HCM Trial for Nonobstructive HCM

HCPLive

Martin Maron, MD, discusses the results of the IMPROVE-HCM trial and how it informs the community on the potential of plozasiran.

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Successful 'first in human' clinical trial of pioneering guidance for heart bypass surgery

Science Daily - Heart Disease

Trial findings suggest that the less invasive approach to heart bypass surgery offers comparable safety and efficacy to established methods and that safety issues inherent to invasive catheterisation investigation can be replaced by a non-invasive technique using CT scan imaging and AI-powered blood flow analysis.

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Microscopic Colitis Patients Almost Twice as Likely to Develop Psoriasis

HCPLive

These nationwide data contribute to the overall body of research on extraintestinal inflammatory conditions among MC patients, highlighting the value of studying the mechanisms involved.

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ACC.24 Convocation Incoming President’s Address: Cathleen Biga, MSN, FACC

American College of Cardiology

Drs. Wilson, Fry, and Kramer; Past Presidents of the College; Trustees; Governors; Partner Society Leaders; Distinguished Guests, Awardees; friends and family; tonight, I am deeply humbled and privileged to stand before you as President of the American College of Cardiology.

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Facilitated Telemedicine’s Potential for Vulnerable Patient Populations, with Andrew Talal, MD

HCPLive

Talal highlights the use of facilitated telemedicine for increasing access to HCV treatment and other areas it might expand access for underserved patient populations.

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Comparison of IVUS-Guided vs. Angiography-Guided Angioplasty for the Outcomes of Drug-Coated Balloon in the Treatment of Femoropopliteal Artery Disease

American College of Cardiology

The goal of the IVUS-DCB trial was to evaluate intravascular ultrasound (IVUS)-guided drug-coated balloon angioplasty compared with angiography-guided drug-coated balloon angioplasty among patients with femoropopliteal artery disease.

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Stopping aspirin one month after coronary stenting procedures significantly reduces bleeding complications in heart attack patients, study suggests

Science Daily - Heart Disease

New research could change standard-of-care guidelines to improve outcomes for heart attack patients after coronary stenting procedures.

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Get to Know ACC’s 73rd President: Cathleen Biga, MSN, FACC

American College of Cardiology

"Who I am NOT has captured a lot of people's attention. So, who am I? I am Cathie Biga, a leader, health care administrator, nurse, executive, mom, wife, nana and I still think of myself as a 'recovering' critical care nurse.

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High-Income Countries Use More Actinic Keratosis Topicals Than Middle-Income Countries

HCPLive

In these data, investigators had investigated the international differences in topical AK medication implementation, including links to countries’ different economic statuses.

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Antisense Drug Slashes High Triglycerides

Med Page Today

(MedPage Today) -- ATLANTA -- A novel antisense mRNA drug slashed triglycerides in higher risk or moderate hypertriglyceridemia patients and in those with extremely elevated levels from familial chylomicronemia syndrome, two randomized phase.

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KarXT Effective in Improving Schizophrenia Symptoms at 52 Weeks

HCPLive

EMERGENT-3 trial showed xanomeline-trospium was effective in improving schizophrenia symptoms at 52 weeks, for participants who took either placebo or KarXT in acute trials.

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PROACT: Do ACE Inhibitors Help Prevent Cardiotoxicity in Patients Treated For Breast Cancer or Lymphoma?

American College of Cardiology

Patients who took the ACE inhibitor enalapril while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels at one month after their last chemotherapy dose compared with those who did not take it, according to results from the PROACT study presented during a Late-Breaking Clinical Trial session at ACC.24 in Atlanta.

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Researchers developed new method for detecting heart failure with a smartphone

Science Daily - Heart Disease

New technology uses a smartphone to analyze heart movement and detect heart failure.

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ACC.24 Convocation Outgoing President’s Address: B. Hadley Wilson, MD, MACC

American College of Cardiology

Last year, we fully embraced the end to the COVID Pandemic. This year – and by this year I mean today – we are experiencing a total eclipse of the sun! Next year we will try and find something equally dramatic to celebrate.

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Obesity at Baseline is a Risk Factor for Poor Treatment Response in RA

HCPLive

Obesity was linked to a lower likelihood of obtaining response to treatment during the 48-week follow-up period.

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Convocation to Pay Tribute to Legacies, Leadership and Learning

American College of Cardiology

Today's Convocation ceremony beginning at 4 p.m. ET will close out ACC.24 by celebrating the College's 75-year history, applauding the many accomplishments of ACC members around the world, welcoming new Fellows and Associates to the ACC family, and recognizing Cathleen Biga, MSN, FACC, as the College's next president.

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Radiotherapy combined with anti-PD-1 and TKI for primary cardiac angiosarcoma considering the joint assessment of TLSs and PD-L1: a case report

Journal of Cardiothoracic Surgery

Background Primary cardiac angiosarcoma(PCA) has a low incidence rate and poor prognosis. Currently, no unified clinical treatment standards are available. Case presentation We report the case of a 48-year-old man presenting chest tightness, breathlessness, and dyspnea. Imaging and postoperative histopathologic studies confirmed PCA and that the tumor had invaded the entire right atrium.

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Randomized, Multicenter, Event-Driven Trial of TAVI Versus SAVR in Patients With Symptomatic Severe Aortic-Valve Stenosis

American College of Cardiology

The goal of the DEDICATE-DZHK6 trial was to evaluate transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and low to intermediate surgical risk.

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Efficacy and safety of tranexamic acid in patients undergoing thoracic surgery: a systematic review and PRIMSA-compliant meta-analysis

Journal of Cardiothoracic Surgery

Perioperative bleeding poses a significant issue during thoracic surgery. Tranexamic acid (TXA) is one of the most commonly used antifibrinolytic agents for surgical patients. The purpose of the current study.

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IVUS-DCB: Does IVUS Improve Outcomes Over Angiography in Femoropopliteal Artery Disease?

American College of Cardiology

One-year success rates from angioplasty to treat femoropopliteal artery disease were significantly higher among patients whose procedures were guided by IVUS alongside angiography compared with those whose procedures were guided by angiography alone, according to results from the IVUS-DCB study presented during a Late-Breaking Clinical Trial session at ACC.24 in Atlanta.