Wed.Aug 21, 2024

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Lifesaving But Not Perfect: Addressing Sleep Health in Patients on Dialysis

HCPLive

Care for dialysis patients often focuses on kidney health, but experts and a patient stress the need for interdisciplinary care that also addresses sleep health.

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Study of pythons could lead to new therapies for heart disease, other illnesses

Science Daily - Heart Disease

In the first 24 hours after a python devours its massive prey, its heart grows bigger, softer and stronger and its metabolism speeds up forty-fold. The extraordinary process could inspire novel treatments for heart disease and metabolic disorders.

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Cardiovascular Event Risk Increases in Year After Statin Discontinuation

HCPLive

A systematic review identified a notable link between the first year of statin discontinuation and the risk of adverse cardiovascular outcomes.

Outcomes 111
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High or low oxygen levels are safe during heart surgery, study finds

Science Daily - Heart Disease

A recent study explored one possible cause -- hyperoxia or high concentrations of oxygen given to such patients during surgery -- as opposed to doses more similar to air. The study concluded that hyperoxia increased oxidative stress during surgery, but this effect did not persist after surgery and did not lead to more acute kidney injury.

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Study Highlights Happiness Differences in European Countries Among Dermatology Patients

HCPLive

These data highlight the necessity of equality in access to treatment and to the future development of psychological intervention measures using country-specific differences.

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Outsized Death Risk for Women With Afib After Heart Surgery

Med Page Today

(MedPage Today) -- After cardiac surgery, women were particularly vulnerable to poor outcomes in the long run if the most common procedural complication had occurred, according to a large retrospective study from two tertiary care centers. Although.

AFIB 86
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TYK2 Inhibition with Zasocitinib Results in Significant Skin Clearance for Psoriasis

HCPLive

This new analysis highlights the effect of this selective allosteric tyrosine kinase 2 inhibitor as an oral treatment for moderate-to-severe psoriasis.

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More Trending

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Epicardial and liver fat implications in albuminuria: a retrospective study

Cardiovascular Diabetology

Albuminuria is considered an early and sensitive marker of kidney dysfunction, but also an independent cardiovascular risk factor. Considering the possible relationship among metabolic liver disease, cardiovas.

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Proposed risk factor tool finds heart failure rates are higher among American Indian adults

Science Daily - Heart Disease

An analysis based on a proposed heart failure risk prediction tool reveals that the incidence of heart failure may be 2- to 3-fold higher among American Indian adults compared to people in other population groups. The risk prediction equation focused on diabetes control and kidney damage indicates that smoking, Type 2 diabetes, high blood pressure, previous heart attack and diabetes-related kidney damage are associated with increased risk of developing heart failure among American Indian adults.

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Positive effects of rhythm and music in brain disorder

Science Daily - Stroke

Music-based movement therapy, known as the Ronnie Gardiner Method, has the potential to contribute to rehabilitation after a stroke and in other brain disorders.

Stroke 91
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Iron Deficiency Cases Persist Over 3 Years in Statewide Health System

HCPLive

Across a statewide cohort, more than half of patients were unable to achieve iron deficiency resolution within 3 years.

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Proposed risk factor tool finds heart failure rates are higher among American Indian adults

American Heart News - Heart News

Research Highlights: An analysis based on a proposed heart failure risk prediction tool reveals that the incidence of heart failure may be 2- to 3-fold higher among American Indian adults compared to people in other population groups. The risk.

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J&J Expands Into Interventional HF Treatments With V-Wave Acquisition

CardiacWire

Johnson & Johnson expanded deeper into heart failure and interventional cardiology, acquiring interatrial shunt-maker V-Wave for $600M upfront and up to $1.7B with certain milestones. V-Wave’s Ventura Interatrial Shunt is intended to treat HFrEF patients, creating a shunt between the left and right atrium to decrease left atrial pressure. V-Wave will become part of J&J MedTech’s cardiovascular portfolio, home to a growing list of recently acquired cardiovascular device businesses.

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NYU Langone creates tool to identify cardiovascular disease risk

Becker's Hospital Review - Cardiology

Researchers from New York City-based NYU Langone Health have created a scoring tool to help physicians identify patients at risk for cardiovascular events.

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The additive effect of the triglyceride-glucose index and estimated glucose disposal rate on long-term mortality among individuals with and without diabetes: a population-based study

Cardiovascular Diabetology

The triglyceride-glucose (TyG) index and estimated glucose disposal rate (eGDR), which are calculated using different parameters, are widely used as markers of insulin resistance and are associated with cardiovascular diseases and prognosis. However, whether they have an additive effect on the risk of mortality remains unclear. This study aimed to explore whether the combined assessment of the TyG index and eGDR improved the prediction of long-term mortality in individuals with and without diabe

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Diabetes Dialogue: Sotagliflozin for T1D and Other ADCES 2024 Highlights

HCPLive

This episode focuses on sotagliflozin in type 1 diabetes and other highlights from the ADCES 2024 annual meeting.

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Blood coagulation in Prediabetes clusters–impact on all-cause mortality in individuals undergoing coronary angiography

Cardiovascular Diabetology

Metabolic clusters can stratify subgroups of individuals at risk for type 2 diabetes mellitus and related complications. Since obesity and insulin resistance are closely linked to alterations in hemostasis, we.

Obesity 52
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Proposed Risk Factor Tool Finds Heart Failure Rates are Higher Among American Indian Adults

DAIC

tim.hodson Wed, 08/21/2024 - 11:32 Aug. 21, 2024 — The incidence rate of heart failure was 2- to 3-fold higher among American Indian populations than rates observed in studies focused on other population groups, such as African American, Hispanic or white adults, in a new study published in the Journal of the American Heart Association. The results were calculated using a new, proposed risk prediction scale for heart failure specifically for American Indian adults.

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Sleep and cognitive symptoms in fibromyalgia

HCPLive

A key opinion leader discusses practical home strategies to improve sleep and manage cognitive symptoms in fibromyalgia patients, while also learning when to seek medical advice and how to differentiate between fibromyalgia-related cognitive issues and those caused by stress.

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Stopping Stress: What Health Science Instructors Need to Know | NHA

Learning + Leading

Healthcare education has always been demanding given the considerable stakes. Equipping tomorrow’s healthcare leaders with the knowledge and tools to make well-informed, split-second decisions is a tall task. In today’s climate, even Herculean.

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Coexisting Cardiometabolic Conditions and Hypercortisolism

HCPLive

Medical experts discuss the implications of finding hypercortisolism in one-third of patients on three or more hypertension medications, the linkage between hypercortisolism and type 2 diabetes as presented in the ‘Pathologic Mechanisms of Hypercortisolism in Type 2 Diabetes’ session, and how hypercortisolism affects diabetes management, including the importance of addressing it and its consequences for patients with difficult-to-control diabetes.

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Poll Results: A Puzzling Jigsaw Tale of a Patient With a History of Congenital Heart Disease Presenting With Syncope

American College of Cardiology

This poll included the following clinical vignette: A 26-year-old woman with a history of cardiac surgeries (unknown details) presents with syncope and palpitations.

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Engaging Primary Care Clinicians in Screening for Hypercortisolism

HCPLive

Medical experts explore why findings from this study are crucial for clinicians managing diabetes, particularly those in primary care settings, and how these insights can impact their approach to patient care.

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20 mm vs. ≥23 mm Balloon-Expandable TAVR Outcomes

American College of Cardiology

Among patients undergoing transcatheter aortic valve replacement (TAVR) with a balloon-expandable valve (BEV), what are the 3-year clinical outcomes associated with a small (20 mm) compared to a larger (≥23 mm) device, and is there a relationship between the discharge echocardiographic (echo) mean gradient (MG) and measured or predicted thresholds for prosthesis-patient mismatch (PPM) with clinical outcomes?

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AI Tool Can Rule Out Unremarkable Pathology on Chest X-Ray

HCPLive

Although the study concluded AI had equal or lower rates of critical misses than radiology reports of remarkable chest radiographs, AI had greater critical miss rates.

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Durability of output-dependent QRS transition and left bundle branch capture in left bundle branch area pacing

HeartRhythm

Although output-dependent QRS transition is a specific indicator that confirms left bundle branch (LBB) capture during left bundle branch area pacing (LBBAP), its durability remains unclear.

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IMPACT-FH: Cascade Strategies Improve Testing for Familial Hypercholesterolemia

HCPLive

Cascade testing strategies significantly increased the detection of FH, with direct contact yielding a 16-fold higher testing rate, according to the IMPACT-FH study.

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Outcome of Cardiac Implantable Electronic Devices in Pediatric Heart Transplant Recipients

HeartRhythm

Among pediatric patients undergoing orthotopic heart transplantation (OHT), 1-12% are reported to need a permanent pacemaker (PPM).1 There are limited studies on the outcomes of PPM placement, and the role of implantable cardioverter-defibrillator (ICD) in pediatric OHT remains unclear. We studied a multi-institutional cohort of pediatric OHT recipients who received cardiac implantable electronic devices (CIED) after transplantation to explore the outcome.

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DAA Treatment Improves Liver-Related Outcomes, Reduces Fibrosis Burden in HCV

HCPLive

Findings suggest the benefit of early HCV detection and treatment with DAAs for improving liver-related outcomes and reducing fibrotic burden.

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Optimized Isochronal Late Activation Methods in the Visualization and Isthmus Identification of Ventricular Tachycardia

HeartRhythm

Catheter ablation of ventricular tachycardia (VT) during sinus rhythm often relies on isochronal late activation mapping (ILAM), a validated means of isthmus identification, whereby points are binned by local activation time (LAT) into 8 isochrones, and isthmus regions are identified as regions with isochronal crowding. The resulting output, however, is inherently discretized and loss of LAT data occurs.

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Family History of Arthritis Increases Risk for Multiple Rheumatological Conditions

HCPLive

Other recent research found that having osteoarthritis increased the risk of developing carpal tunnel syndrome.

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Amino Acid Infusion to Protect Kidney Function after Cardiac Surgery

The New England Journal of Medicine

Cardiac surgery–associated acute kidney injury (AKI) is linked to adverse outcomes including an increased risk of death, postoperative complications, and higher rates of incident or progressive chronic kidney disease.1,2 The cause of cardiac surgery–associated AKI is multifactorial. It is also well recognized that hemodynamic alterations can result in.

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Digoxin: monitoring, limitations of its use, and managing toxicity

The British Journal of Cardiology

Digoxin is widely used in the management of atrial fibrillation (AF) and the heart failure (HF) syndrome. Significant numbers of people are prescribed digoxin every year; 2,560,941 prescriptions for digoxin were issued by general practitioners in England in 2023. 1 Digoxin predominantly acts by increasing vagal tone. This reduces heart rate and increases diastolic filling of the left ventricle (LV), resulting in an improvement in LV function.

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Voltage-guided Pulmonary Vein Isolation for Atrial Fibrillation

HeartRhythm

Bipolar voltage amplitude is capable of helping determine the ideal lesion size index (LSI) setting during radiofrequency (RF) ablation for atrial fibrillation (AF).

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The modern-day role of digoxin in heart failure and atrial fibrillation – benefits and limitations

The British Journal of Cardiology

Digoxin has been used in the management of chronic heart failure (HF) and atrial fibrillation (AF) for over 250 years. It is the only drug that combines an inotropic effect with a reduction in ventricular rate in AF. Therefore, in theory it should be an ideal treatment for HF, especially when there is co-existent AF. However, due to concerns about arrhythmia and toxicity, its use has declined dramatically over recent decades.

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Cardiovascular Management of Aortopathy in Children: Key Points

American College of Cardiology

The following are key points to remember from a scientific statement on cardiovascular management of aortopathy in children.

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Digitalis – from Withering to the 21st century

The British Journal of Cardiology

More than 200 years have passed since William Withering’s ground-breaking work on the medical use of foxglove for the treatment of dropsy. Its derivative, digoxin, remains one of the most heavily debated drugs in cardiovascular medicine. While its use predated the era of randomised control trial evidence or even a complete understanding of its mechanism of action, it has endured against a changing scientific and therapeutic landscape.