Sun.Jul 21, 2024

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Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

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Doctors who know the impact of pregnancy complications on our cardiac risk

Heart Sisters

I didn't even know until after my heart attack that a preeclampsia diagnosis during my first pregnancy meant I was at 2-3 times higher risk for heart disease.

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Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01060-8 In this Roadmap arising from an NHLBI workshop, Chew and colleagues explore the use of retinal imaging biomarkers for the prediction, diagnosis and monitoring of systemic cardiovascular diseases. The authors identify knowledge gaps and research opportunities to translate retinal imaging biomarkers into clinical practice.

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Longitudinal assessment of coronary plaque regression related to sodium–glucose cotransporter-2 inhibitor using coronary computed tomography angiography

Cardiovascular Diabetology

Sodium–Glucose Cotransporter-2 Inhibitor (SGLT2i) is a novel oral drug for treating type 2 diabetes mellitus (T2DM) with demonstrated cardiovascular benefits. Previous studies in apolipoprotein E knockout mice.

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Cardiac sarcomere turnover by unidirectional replacement of proteins

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01065-3 A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by newly translated proteins. Sarcomere turnover occurs at a similar rate within cardiomyocytes and across the heart and slows with ageing.

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Genetic predisposition to type 2 diabetes mellitus and aortic dissection: a Mendelian randomisation study

Frontiers in Cardiovascular Medicine

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits. The study sought to verify the inverse relationship between T2DM and AD using a more robust and unbiased method, building on the observational studies previously established.Materials and methodsThe study employed a two-sample and multivari

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Successful pharmaco-invasive approach using a lower alteplase dose and VA-ECMO support in high-risk pulmonary embolism: case report

Frontiers in Cardiovascular Medicine

Despite the elevated mortality rates associated with high-risk pulmonary embolism (PE), this condition remains understudied. Data regarding the effectiveness and safety of invasive therapies such as venoarterial extracorporeal membrane oxygenation (VA-ECMO) in this patient population remains controversial. Here, we present the case of a 61-year-old male with high-risk PE associated with refractory cardiac arrest and cardiogenic shock who underwent a combination of extracorporeal cardiopulmonary

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Study Links Maternal Asthma to Blinding Eye Disease in Premature Infants

HCPLive

New research presented at ASRS 2024 links maternal asthma to a higher risk of advanced retinopathy of prematurity.

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An implementation manual for an interprofessional enhanced recovery after surgery protocol in cardiac surgery following international established frameworks

Frontiers in Cardiovascular Medicine

IntroductionEnhanced Recovery After Surgery (ERAS) protocols represent a paradigm shift in perioperative care, aim to optimize patient outcomes and accelerate recovery. This manual presents findings from implementing the INCREASE study, a bicentric prospective randomized controlled trial focusing on ERAS in minimally invasive heart valve surgery.MethodsUtilizing the Consolidated Framework for Implementation Research (CFIR) and the Template for Intervention Description and Replication (TIDieR), t

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Highlights From the Circulation Family of Journals

Circulation

Circulation, Volume 150, Issue 4 , Page 336-339, July 23, 2024.

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Large Language Models as Partners in Medical Literature

HeartRhythm

The role of generative artificial intelligence (AI), specifically large language models (LLM) in academic medicine, is polarizing. Some journal editors embrace their potential to summarize complex data, while others express concern about their potential abuse1,2. This divide merits an examination of the benefits and limitations of employing LLMs in scholarly work.

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What is coronary artery bypass surgery CABG?

All About Cardiovascular System and Disorders

Just as we build bypass roads when a city road is too congested, blood vessels of the heart can by bypassed when they have too many total or partial blocks. Coronary arteries are blood vessels supplying oxygenated blood to the heart. As age advances and depending on risk factors like heredity, smoking, high blood pressure and diabetes, fat build up occurs in these blood vessels.

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Introduction to Wearable Technology in Arrhythmia Management

HeartRhythm

The global health challenge posed by cardiac arrhythmias, particularly atrial fibrillation (AF), is significant, with heightened risks of stroke, heart failure, and systemic embolism1. Traditional arrhythmia detection has often missed transient or asymptomatic episodes, relying on symptomatic presentations and episodic monitoring. The introduction of wearable technology is a potential game-changer, enabling continuous, patient-centric monitoring, and early intervention, a cornerstone for managin

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No longer forgotten: more understanding of tricuspid valve replacement.

The American Journal of Cardiology

Publication date: Available online 20 July 2024 Source: The American Journal of Cardiology Author(s): Louis Stein, Bruce Haik, Arash Salemi

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Factors of Engagement in Research After Graduation from EP Fellowship: an HRS Survey

HeartRhythm

The declining number of electrophysiologists pursuing academic research careers could negatively impact innovation for patients with heart rhythm disorders in the coming decades.

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RNA Editing Holds Promise for Hypertrophic Cardiomyopathy Therapy

Circulation

Circulation, Volume 150, Issue 4 , Page 299-301, July 23, 2024.

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August 2024 Stroke Highlights

Stroke Journal

Stroke, Volume 55, Issue 8 , Page 1961-1961, August 1, 2024.

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Global Collaborative Cardiovascular Research: The Collective Wisdom of Countries

Circulation

Circulation, Volume 150, Issue 4 , Page 258-260, July 23, 2024.

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Stroke Literature Synopses (Preclinical)

Stroke Journal

Stroke, Volume 55, Issue 8 , Page e236-e237, August 1, 2024.

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Misdiagnosis From a Smart Watch

Circulation

Circulation, Volume 150, Issue 4 , Page 340-342, July 23, 2024.

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Sex differences in clinical profile, left ventricular remodeling and cardiovascular outcomes among diabetic patients with heart failure and reduced ejection fraction: a cardiac-MRI-based study

Cardiovascular Diabetology

Heart failure with reduced ejection fraction (HFrEF) is associated with a high rate of mortality and morbidity. Evidence has shown that sex differences may be an important contributor to phenotypic heterogenei.