Tue.Apr 30, 2024

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CDC: Premature Mortality for Top Causes of Death Higher in Rural Areas

Med Page Today

(MedPage Today) -- Americans living in rural areas had higher rates of preventable premature mortality from the five leading causes of death than those living in urban areas during the years 2010-2022, and the divide only appears to be growing.

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Researchers identify over 2,000 genetic signals linked to blood pressure in study of over one million people

Science Daily - Heart Disease

Researchers have discovered over a hundred new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure. In total, over 2,000 independent genetic signals for blood pressure are now reported, demonstrating that blood pressure is a highly complex trait influenced by thousands of different genetic variants.

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Recognizing Stigma's Impact on Care for Alcohol-Related Liver Disease

HCPLive

In the first segment of this HCPLive special report, experts discuss the stigma surrounding alcohol use disorder and alcohol-associated liver disease.

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The Society of Thoracic Surgeons Launches New Valve Surgery Risk Calculators

DAIC

milla1cf Tue, 04/30/2024 - 13:03 April 30, 2024 — The expanding use of transcatheter technologies has changed the landscape in the treatment of valvular disease in adult cardiac patients, with valve surgery rapidly shifting to more complex interventions frequently involving other concomitant procedures. To inform heart team and patient decision-making on valve surgery, The Society of Thoracic Surgeons (STS) has launched new risk calculators for isolated tricuspid valve repair and replacement ;

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Mobile Health App Improves Treatment Compliance, Health Knowledge in Gout

HCPLive

Patients placed in the intervention group reported significant improvements in gout knowledge levels over time compared with controls throughout the 24-week study period.

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Advance in the Treatment of Acute Heart Failure Identified

DAIC

Getty Images milla1cf Tue, 04/30/2024 - 12:56 April 30, 2024 — A multicenter study led by Vanderbilt University Medical Center ( VUMC ) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heart failure , a leading cause of hospitalization and death. The drug, dapagliflozin, was initially approved for the treatment of Type 2 diabetes, but it since has been shown to reduce the risk of hospitalization for heart failure and death in patients wi

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Deep Learning–Based Assessment of Built Environment From Satellite Images and Cardiometabolic Disease Prevalence

JAMA Cardiology

This cross-sectional study investigates the association between cardiometabolic disease prevalence in the US and deep learning–based assessment of the built environment from satellite imagery.

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QT-Prolonging Meds Commonly Doled Out to Dialysis Patients

Med Page Today

(MedPage Today) -- Non-nephrologists frequently prescribed QT-prolonging medications with known torsades de pointes (TdP) risk to older dialysis-dependent patients, and often these prescriptions came from nonacute settings, a cross-sectional study.

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What is the rhythm?

Dr. Smith's ECG Blog

A patient was found down approximately 30 minutes after taking methamphetamine. Bystander CPR. Medics found patient in PEA arrest. He was resuscitated into a perfusing rhythm. He went in and out of arrest until arrival at the ED. Here is the only prehospital 12-lead: Sinus tachycardia, somewhat wide QRS, Ischemia Here is the first ED ECG: What is the rhythm here?

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Air Quality Issues Due to Particle Pollution with John Balmes, MD

HCPLive

This segment of the latest Lungcast episode featured a discussion over the ALA’s State of the Air Report and the impacts of particle pollution.

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A Life Raft: A Parent’s Experience using the Guided Questions Tool

Conquering CHD

Esther Kinney The Guided Questions tool ( in PDF ) was designed to help parents promote discussion with their cardiac care team. At the Conquering CHD (CCHD), we believe that information is important when making decisions about the care of your child. The tool is broken into three key aspects of care: quality data, patient experience and looking ahead.

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Considering Safety of Gene Therapy for Retinal Diseases

HCPLive

Experts continue their discussion of gene therapy, highlighting safety concerns and the need for more trials and data.

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Devices Flop for Severe PAD; CPR on LVAD Patients; Cancer Drugs for Heart Disease?

Med Page Today

(MedPage Today) -- For patients with peripheral artery disease (PAD) and chronic limb-threatening ischemia, drug-eluting stents and drug-coated balloons did not improve amputation-free survival compared with balloon angioplasty alone in the BASIL.

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Coronary Artery Calcium and Polygenic Risk Scores For Cardiovascular Risk Prediction: Results From Two Population-Based Studies

American College of Cardiology

Cardiovascular disease (CVD) risk estimation is a critical component of clinician–patient shared decision making, which is used to guide the initiation and intensification of preventive therapies.

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Discussing Risankizumb, Differences in IL-23 Inhibitor Epitopes with Christopher Bunick, MD, PhD

HCPLive

This interview with Bunick featured a discussion of his team’s recent data comparing anti-IL-23 biologics, epitopes, and comparisons with risankizumab.

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Important Notice: All ACC Web Platforms Will Be Unavailable From May 10-21

American College of Cardiology

Important Notice: All ACC-related web platforms will be unavailable from Friday, May 10 until Tuesday, May 21 as part of system-wide upgrades to ACC's digital infrastructure.

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The Status of Gene Therapy Development for Retinal Diseases

HCPLive

Experts shift to the prospect of gene therapy in treating retinal diseases.

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Cardiology, heart surgery reimbursements down at least 29%

Becker's Hospital Review - Cardiology

"Discover the alarming findings of a recent study on Medicare reimbursements, revealing a 29% decrease for cardiology and even greater declines for cardiac

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Addressing Stigma to Improve Outcomes in Alcohol-Related Liver Disease

HCPLive

The second segment of a special report stresses the importance of cross-specialty collaboration with hepatology and psychiatry when treating alcohol-related liver disease.

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Scientists find cancer-like features in atherosclerosis, spurring opportunity for new treatment approaches

Science Daily - Heart Disease

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease. Atherosclerosis is characterized by a narrowing of arterial walls and can increase risk of coronary artery disease, stroke, peripheral artery disease, or kidney disorders.

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Lebrikizumab for Atopic Dermatitis Resubmitted for FDA Approval After Previous Rejection

HCPLive

The decision by Eli Lilly to resubmit lebrikizumab to the FDA for adults and adolescents with eczema is expected to receive a response in the second half of the year.

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A Novel Agent Fails to Improve Outcomes in Diabetic Cardiomyopathy

NEJM Journal Watch - Cardiology

The highly selective aldose reductase inhibitor AT-001 did not improve exercise capacity in a randomized trial.

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FDA Authorizes Autonomous AI for Portable Diabetic Retinopathy Screening

HCPLive

AEYE Health receives clearance for the first artificial intelligence solution to allow fully autonomous screening for diabetic retinopathy using a portable device.

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Wide Complex Tachycardia in a Middle-Aged Woman With Diarrhea

JAMA Cardiology

A woman in her mid-60s with a history of paroxysmal atrial fibrillation and hypertension presents with 3 days of nausea, vomiting, and diarrhea. What would you do next?

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Endocrinology Month in Review: April 2024

HCPLive

The HCPLive Endocrinology month in review for April 2024 spotlights SURMOUNT-OSA, STEP HFpEF DM, new ACP guidelines for T2D, and more!

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Thromboembolic Prevention in Atrial High-Rate Episodes: Is There Benefit? (NOAH-AFNET 6 Study)

American College of Cardiology

Prolonged atrial arrhythmias expose patients to increased risks of thromboembolism. The results of a meta-analyses revealed a fourfold increased risk of stroke and systemic embolism in patients with atrial high-rate episodes (AHRE) lasting ≥30 sec.

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Machine Learning Approach Effectively Predicts Remission in RA Following TNF Treatment

HCPLive

Lasso demonstrated advantages in predicting clinical remission in patients with RA treated with TNF, with a specificity of 69.9% and sensitivity of 61.7%.

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Management of peripheral arterial disease in the context of a multidisciplinary limb program

Frontiers in Cardiovascular Medicine

Peripheral artery disease (PAD) continues to increase in prevalence worldwide due to risk factors such as advanced age, diabetes mellitus, and obesity. Critical limb ischemia (CLTI) is the advanced form of PAD that can result in a lack of healing and limb loss as the most devastating consequence. Patients with PAD, especially CLTI, benefit from multidisciplinary care to optimize outcomes by reducing cardiovascular morbidity and mortality and preventing lower extremity amputation.

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Analysis of core outcome set reporting in coronary intervention trials

Open Heart

Background This paper will focus on outcome reporting within percutaneous coronary intervention (PCI) trials. A core outcome set (COS) is a standardised set of outcomes that are recommended to be reported in every clinical trial. Using a COS can help to ensure that all relevant outcomes are consistently reported across clinical trials. In 2018, the European Society of Cardiology outlined the only COS published for PCI trials.

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Risk factors and prediction model for new-onset hypertensive disorders of pregnancy: a retrospective cohort study

Frontiers in Cardiovascular Medicine

Background and aimsHypertensive disorders of pregnancy (HDP) is a significant cause of maternal and neonatal mortality. This study aims to identify risk factors for new-onset HDP and to develop a prediction model for assessing the risk of new-onset hypertension during pregnancy.MethodsWe included 446 pregnant women without baseline hypertension from Liyang People's Hospital at the first inspection, and they were followed up until delivery.

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Psychological Aspects Of Heart Disease Surgery Recovery

MIBHS

There’s no denying that heart disease surgery is a significant life event. If you’ve undergone it or have plans to do so in the future, you should understand the psychological aspects of the recovery process. Below, with Minimally Invasive and Bloodless Heart Surgery with Dr. Ciuffo , we’ll go over what they are and what you can do to cope with them so you can stay positive and keep your emotions in check.

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How Does Exercise Prevent Heart Disease?

All About Cardiovascular System and Disorders

Dr. Paul Dudley White, the famous physician who has taught many a luminary in the field of cardiology once wrote that heart disease before eighty is our fault and not God’s will or nature’s will. This means that he recognized long back, the role of life-style modification in preventing heart disease. Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovascular disease.

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Older Age Impacts Health, Birth Outcomes in Hospitalized Pregnant Patients with HCV

HCPLive

Findings highlight an increase in hospitalization among pregnant patients with HCV, further describing age’s impact on mortality, cirrhosis, preterm births, and stillbirths.

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Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity

JAMA Cardiology

This cohort study investigates the cardiovascular disease associations and genetic determinants of epicardial and pericardial adiposity.

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Demographic Factors Influence Medicine Adherence, Satisfaction for RA Treatment

HCPLive

Demographic, psychosocial, and clinical factors—along with patient-provider relationships—all impact medication adherence and patient satisfaction with RA treatment.

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PO-04-082 THE IMPACT OF ATRIAL FIBRILLATION ON CLINICAL OUTCOMES IN HEART FAILURE WITH MID-RANGE AND PRESERVED EJECTION FRACTION PATIENTS

HeartRhythm

The combined effect of Left Ventricular Ejection Fraction (LVEF) and the presence of Atrial Fibrillation (AF) on clinical outcomes in heart failure (HF) patients remains complex.

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Gastroenterology Month in Review: April 2024

HCPLive

This April 2024 month in review highlights World IBS Day, updates in the gastroenterology pipeline, ACP Internal Medicine meeting coverage, and recent IBD research.