Wed.Mar 20, 2024

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8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death

Science Daily - Heart Disease

A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.

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Novel Oral Antihypertensive Gets FDA's Blessing

Med Page Today

(MedPage Today) -- The FDA has approved aprocitentan (Tryvio), making it the first endothelin receptor antagonist for the treatment of high blood pressure (BP), Idorsia Pharmaceuticals announced on Wednesday. The once-daily oral medication is.

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Exposure to tobacco before birth significantly increased risk of Type 2 diabetes in adults

American Heart News - Heart News

Research Highlights: Exposure to tobacco before birth and beginning smoking during childhood or adolescence were significantly associated with the development of Type 2 diabetes in adulthood, according to a study of nearly half a million adults in the.

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FDA Approves Aprocitentan (Tryvio) for Treatment-Resistant Hypertension

HCPLive

Idorsia Ltd. announced the FDA's approval of aprocitentan (Tryvio) for treatment-resistant hypertension on March 20, 2024.

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Free, weekly fresh produce improved diet, physical activity and reduced CVD risk factors

American Heart News - Heart News

Research Highlights: After 16 weeks of free, weekly home delivery of fresh produce, study participants boosted their fruit and vegetable consumption by almost ½ of a serving per day and added 42 minutes to their weekly level of physical activity. One.

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Questioning Intermittent Fasting’s Cardiovascular Impact

CardiacWire

A new AHA study shocked the world this week, suggesting that intermittent fasting might significantly increase people’s risk of cardiovascular death, sparking a wave of media coverage, and a frenzy of criticisms from the cardiologist and scientific communities. Time-restricted eating, which is a type of intermittent fasting, involves limiting eating to a specific number of hours per day (e.g. 4 or 8 hours) and fasting for the rest of the day.

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Treating anxiety, depression in people with heart disease reduced ER visits, hospitalizations

Medical Xpress - Cardiology

Treating anxiety and depression reduced emergency room visits and rehospitalizations among people with heart disease, according to new research published today in the Journal of the American Heart Association.

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Time-restricted Eating Increases Your Risk of Cardiovascular Death? Don't Buy the Headlines.

Physiologically Speaking

When I read a news headline about science, I try to first apply Hanlon’s razor: not attributing to malice what can likely be explained by incompetence. This proves to be difficult almost daily, increasingly so in the age where clickbait sells. This week is no different. On Monday, several news outlets posted headlines regarding a new “study” with the alarmist claim that “8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death.” As I write t

Diet 114
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Embracing Cardiac Imaging: Overcoming Barriers, Adopting In-house Solutions, and Navigating Future Advancements

DAIC

Cardiac CT scans, recommended by the American College of Cardiology (ACC) and the American Heart Association (AHA) as the primary testing strategy for patients with acute chest pain, are necessary for evaluating cases and determining treatment plans. Despite its importance, a substantial number of U.S. patients who require a cardiac CT miss out on receiving one due to limited access.

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ARDS Due to COVID-19 Linked to Heart Damage Risk

HCPLive

New data from NIH investigators show acute respiratory distress syndrome from COVID-19 infection may trigger heart inflammation in patients.

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Treating anxiety, depression in people with heart disease reduced ER visits, hospitalizations

Science Daily - Heart Disease

Treating anxiety and depression significantly reduced hospital readmission and emergency room visits in people with heart disease.This may be the first study to show that treating anxiety and depression with medication or psychotherapy has a significant impact on heart disease outcomes.

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Impact of Psychosocial Factors Highlighted Regarding Psoriatic Arthritis Joint Pain

HCPLive

The findings in this research letter allow for greater understanding of residual joint pain modulators, with the overall goal being to improve health outcomes for those with PsA.

Research 105
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Severe lung infection during COVID-19 can cause damage to the heart

Medical Xpress - Cardiology

SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a study has found. The research, published in the journal Circulation, specifically looked at damage to the hearts of people with SARS-CoV-2-associated acute respiratory distress syndrome (ARDS), a serious lung condition that can be fatal.

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Severe Lung Infection During COVID-19 Can Cause Damage to the Heart

DAIC

Getty Images milla1cf Wed, 03/20/2024 - 19:16 March 20, 2024 — SARS-CoV-2 , the virus that causes COVID-19 , can damage the heart even without directly infecting the heart tissue, a National Institutes of Health -supported study has found. The research, published in the journal Circulation, specifically looked at damage to the hearts of people with SARS-CoV2-associated acute respiratory distress syndrome ( ARDS ), a serious lung condition that can be fatal.

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Severe lung infection during COVID-19 can cause damage to the heart

Science Daily - Heart Disease

SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a new study has found. The research specifically looked at damage to the hearts of people with SARS-CoV2-associated acute respiratory distress syndrome (ARDS), a serious lung condition that can be fatal. But researchers said the findings could have relevance to organs beyond the heart and also to viruses other than SARS-CoV-2.

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FDA Breakthrough Device Designation for Biotronik Freesolve Below-the-Knee Resorbable Magnesium Scaffold (RMS)

DAIC

milla1cf Wed, 03/20/2024 - 18:50 March 20, 2024 — Biotronik has been granted Breakthrough Device Designation (BDD) from the US Food and Drug Administration (FDA) for the Freesolve below-the-knee resorbable magnesium scaffold (BTK RMS). The Freesolve BTK RMS is designed for individuals suffering from chronic limb-threatening ischemia (CLTI). CLTI is the most severe form of peripheral arterial disease (PAD), estimated to affect 11% of the 200 million people suffering from PAD globally.

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Positive Phase 2 Data Shows Benefit of Lanifibranor with Empagliflozin for MASH, T2D

HCPLive

The phase 2, proof-of-concept LEGEND trial achieved its primary efficacy endpoint for absolute reduction in HbA1c at week 24 with lanifibranor alone or in combination with empagliflozin.

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PECA Labs Receives Expanded CE Mark for exGraft Family of Vascular Grafts, Allowing for Expandability Designed to Match Growth or Help Avoid Restenosis

DAIC

milla1cf Wed, 03/20/2024 - 18:53 March 20, 2024 — PECA Labs , a medical device company reimagining the field of vascular grafts and valves with durable polymeric cardiovascular devices designed to fit, grow, and last, has received an additional CE Mark for its exGraft family of vascular grafts , expanding its on-label use. exGraft vascular grafts are intended for use as vascular prostheses for replacement or bypass of diseased or injured vessels, and with the new clearance, exGraft now inclu

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Key Issues as Wearable Digital Health Technologies Enter Clinical Care

The New England Journal of Medicine

The authors address the issues that must be confronted if we are to integrate the use of wearable digital health technologies into clinical care in a way that provides an enduring benefit to patients.

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Sacubitril/Valsartan for Worsening Heart Failure

American College of Cardiology

What is the safety and efficacy of sacubitril/valsartan when initiated during hospitalization or soon after a worsening heart failure event and among patients with HF across the spectrum of ejection fraction?

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What My Patients Struggle With.

Dr. Paddy Barrett

"Frustrated, lost and confused." That was the main feedback I got back from thousands of readers when I asked them what their experience was in trying to work with existing healthcare systems to put a plan in place to prevent heart disease. This is not good. Heart disease is the leading cause of death worldwide, and with the right approaches, 80% or more can be prevented at an early age.

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Skeleton-wide study of blood cell formation offers new ways to treat blood cancers, infections

Medical Xpress - Cardiology

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

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SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system

Frontiers in Cardiovascular Medicine

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by an aggressive inflammatory response known as hypercytokinemia, contributing to endothelial damage. Although vaccination has reduced hospitalizations, hypercytokinemia persists in breakthrough infections, emphasizing the need for disease models mimicking this response.

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ACC Announces Next Clinical Trials Research Program Participants

American College of Cardiology

The ACC has selected 50 learners for its 2024-2025 Clinical Trials Research (CTR) program, of whom 28 structural heart cardiologists and surgeons will participate in the program's new REACH (Research, Equity, and Access for Cardiac Health) cohort.

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Case Report: A left ventricular pseudoaneurysm detected by cardiac magnetic resonance more than 1 year after a percutaneous transluminal coronary intervention

Frontiers in Cardiovascular Medicine

Pseudoaneurysm is a rare but lethal complication of acute myocardial infarction. In this study, we present a unique case of a patient with left ventricular free wall rupture detected by cardiac magnetic resonance more than 1 year after a percutaneous transluminal coronary intervention.

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Lp(a) Assay Methods Similarly Predictive of MACE Reduction with Alirocumab

HCPLive

A recent comparison of changes in Lp(a) mass and molar concentrations found that each assay method was similarly predictive of MACE reductions with alirocumab.

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Deep Learning For Differentiation of Constrictive Pericarditis and Restrictive Cardiomyopathy Using Echocardiography

American College of Cardiology

Commentary based on Chao CJ, Jeong J, Arsanjani R, et al. Echocardiography-based deep learning model to differentiate constrictive pericarditis and restrictive cardiomyopathy.

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Rebecca Andrews, MD: MDD Performance Measures Review Highlight Need for Tweaking

HCPLive

In an interview with HCPLive, Rebecca Andrews, MD, provided insight into the way the American College of Physicians voted on the performance measures for MDD.

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Eagle’s Eye View: Quantitative Coronary Angiography vs Intervascular Ultrasound to Guide PCI, Paclitaxel-Coated Balloon Catheters, PCI vs Coronary Artery Bypass Grafting in Left Main Disease and Diabetes

American College of Cardiology

In this week’s View, Dr. Eagle looks at the difference between quantitative coronary angiography versus intervascular ultrasound to guide PCI. He then discusses paclitaxel-coated balloon catheters vs uncoated balloon angioplasty for treating coronary in-stent restenosis.

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Diabetes Dialogue: Stelo News and Dexcom CGM Updates, with Jake Leach

HCPLive

Jake Leach, COO of Dexcom, joins the podcast to discuss the historic clearance of the Stelo sensor and other updates in CGM from the company.

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Myocarditis sufferer educates students about healthy lifestyles

Medical Xpress - Cardiology

Shaunté Brewer didn't know that her health was in danger at age 13. As the Chicago resident recalls, she was more focused on passing her softball test in gym than on her prevalent cough. Fortunately, Brewer's mother determined that the sound and persistence of her daughter's cough called for a trip to the hospital.

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Rebecca A. Andrews, MD: Issues and Steps to Improve MDD Performance Measures

HCPLive

Vice Chair of the Performance Measurement Committee Rebecca A. Andrews spoke to HCPLive about the challenges with performance measures for treating major depressive disorder.

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Valvar bypass surgery to ameliorate persistent lower limb edema caused by post-thrombotic syndrome: a case report and literature review

Journal of Cardiothoracic Surgery

Obstruction and/or reflux compromise during venous emptying can facilitate different pathophysiologies in chronic venous insufficiency (CVI). We present a patient with persistent lower limb CVI edema caused by.

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Nationwide Study Highlights Infection Risk Levels for PsA Patients on Different Treatments

HCPLive

These data on patients with psoriatic arthritis point to risk levels for new adalimumab users as well as users of ustekinumab and etanercept.

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Excimer Laser Coronary Angioplasty

All About Cardiovascular System and Disorders

Transcript of the video: Conventional balloon angioplasty enlarges the vessel a bit as well as plasters the plaque on to the vessel wall, while laser angioplasty is a new technique, also known as laser atherectomy, in which excimer laser, which is a monochromatic source of light, is used to vaporize the plaque or thrombus by producing heat and shock waves.

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Rheumatic, Immune-Mediated Diseases Increase Risk of Childbearing Problems, Adverse Pregnancy Outcomes

HCPLive

An analysis of data from more than 5 million people suggests rheumatic and immune-mediated diseases were associated with increased rates of childlessness and elevated risk of adverse pregnancy outcomes.

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Evaluation of JVP

All About Cardiovascular System and Disorders

Transcript of the video: Now we will discuss the basic principles of evaluation of jugular venous pressure and jugular venous pulse. These are assessed in the internal jugular vein and not in the external jugular vein. To revise the anatomy lessons, this is the external jugular vein and this is the internal jugular vein. Now, why we should not be looking at external jugual vein, though it is much easier to find out is that, in lower portion, it may be kinked so that it may not reflect the true r