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(MedPage Today) -- TOKYO (AP) -- Five people who took a Japanese health supplement have died and more than 100 have been hospitalized as of Friday, a week after a pharmaceutical company issued a recall of the products, officials said. Osaka.
New data show COPD and IPF, among other interstitial lung diseases, are more significantly associated with poor 30-day outcomes from COVID-19 than asthma.
Taking a single pill that combines medications targeting cardiovascular disease-related conditions was shown long ago to lower the risk of death from such causes, including heart attacks and strokes.
Getty Images milla1cf Mon, 04/01/2024 - 08:21 April 1, 2024 — Roughly 25,000 Americans die each year from valvular heart disease, but researchers from Rutgers Health and other institutions conclude that new technology could soon help doctors slash that number. “We are witnessing a paradigm shift in how valvular heart diseases are diagnosed and treated,” said Partho Sengupta , Henry Rutgers Professor of Cardiology and chief of the Division of Cardiovascular Disease and Hypertension at Rutgers Ro
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Results offer important guidance for healthcare providers to develop tailored treatment strategies that align with the unique needs and preferences of individual patients.
University of Virginia School of Medicine researchers have discovered a gene on the Y chromosome that contributes to the greater incidence of heart failure in men. The work is published in the journal Nature Cardiovascular Research.
Resource Isolated Tricuspid Valve Surgery Risk Calculator kchalko Mon, 04/01/2024 - 13:31 Isolated Tricuspid Valve Surgery Risk Calculator Existing literature on national surgical outcomes of isolated tricuspid valve repair or replacement is based on data from over a decade ago and may not reflect current practice results. Real-world contemporary data from the STS Adult Cardiac Surgery Database demonstrate increased overall volumes compared to prior years, and improved outcomes for both isolated
Resource Isolated Tricuspid Valve Surgery Risk Calculator kchalko Mon, 04/01/2024 - 13:31 Isolated Tricuspid Valve Surgery Risk Calculator Existing literature on national surgical outcomes of isolated tricuspid valve repair or replacement is based on data from over a decade ago and may not reflect current practice results. Real-world contemporary data from the STS Adult Cardiac Surgery Database demonstrate increased overall volumes compared to prior years, and improved outcomes for both isolated
In response to a meal, insulin drives hepatic glycogen synthesis to help regulate systemic glucose homeostasis. The mechanistic target of rapamycin complex 1 (mTORC1) is a well-established insulin target and contributes to the postprandial control of liver lipid metabolism, autophagy, and protein synthesis. However, its role in hepatic glucose metabolism is less understood.
A systematic review of 14 clinical practice guidelines found that guidance on inpatient management of elevated blood pressure (BP) without symptoms is lacking. According to the authors, this lack of guidance may contribute to variable practice patterns. The review is published in Annals of Internal Medicine.
Mutations in genes encoding chromatin modifiers are enriched among mutations causing intellectual disability. The continuing development of the brain postnatally, coupled with the inherent reversibility of chromatin modifications, may afford an opportunity for therapeutic intervention following a genetic diagnosis. Development of treatments requires an understanding of protein function and models of the disease.
Obesity is often associated with multiple comorbidities. However, whether obese subjects with hyperlipidemia in the absence of other complications have worse cardiac indices than metabolically healthy obese su.
Dallas, 1 de abril de 2024 - La American Heart Association (la Asociación Americana del Corazón) y Los Angeles Rams brindaron educación que salva vidas a 200 jóvenes futbolistas, entrenadores y educadores en un evento de entrenamiento sobre reanimación.
The integrated stress response (ISR) is a highly conserved biochemical pathway involved in maintaining proteostasis and cell health in the face of diverse stressors. In this Review, we discuss a relatively noncanonical role for the ISR in neuromodulatory neurons and its implications for synaptic plasticity, learning, and memory. Beyond its roles in stress response, the ISR has been extensively studied in the brain, where it potently influences learning and memory, and in the process of synaptic
Researchers have discovered a gene on the Y chromosome that contributes to the greater incidence of heart failure in men, opening the door to new treatments.
Physical activity is one of the best ways to improve overall health and manage stress. Unfortunately, 1 in 4 adults in the U.S. are sedentary for more than eight hours each day, according to the U.S. Centers for Disease Control & Prevention (CDC). This can have negative consequences on physical and mental health. The American Heart Association established National Walking Day in 2007.
Identifying reliable prognostic markers is crucial for the effective management of hypertension. The neutrophil-to-lymphocyte ratio (NLR) has emerged as a potential inflammatory marker linked to cardiovascular.
In a long-term study published in the journal Epidemiology, researchers from Tel Aviv University (TAU) examined the association between a greener environment, which is most likely saturated with vegetation, and the mortality rate of coronary heart patients after undergoing bypass surgery—which is considered a traumatic event from both the physical and mental aspects.
DALLAS, April 1, 2024 — The Global Cardiovascular Research Funders Forum invite scientific researchers to compete in a new data challenge, hosted on the American Heart Association’s Precision Medicine Platform. The challenge is designed to better.
Stroke, Ahead of Print. BACKGROUND:Health care teams along the stroke recovery continuum have a responsibility to support care transitions and return to the community. Ideally, individualized care will consider patient and family preferences, best available evidence, and health care professional input. Person-centered care can improve patient-practitioner interactions through shared decision-making in which health professionals and institutions are sensitive to those for whom they provide care.
In this review of the top stories in dermatology in March, several were highlighted such as the recent report on benzene in skincare products and the FDA’s approval of spesolimab for generalized pustular psoriasis.
What is the prognostic importance of an increase in N-terminal pro–B-type natriuretic peptide (NT-proBNP) and outpatient diuretic intensification (ODI) as markers of disease progression in a cohort of patients with transthyretin cardiac amyloidosis (ATTR-CA)?
DALLAS, April 1, 2024 — The American Heart Association and the Los Angeles Rams brought lifesaving education to 200 youth football participants, coaches and educators at a cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED).
Nature Reviews Cardiology, Published online: 02 April 2024; doi:10.1038/s41569-024-01022-0 After myocardial infarction, the heart secretes small extracellular vesicles with pro-neoplastic properties that can accelerate tumour growth when taken up by cancer cells.
In this special edition of Eagle’s Eye View, Dr. Eagle highlights the latest science and innovation being presented at ACC.24 in Atlanta, Georgia from April 6-8. He gives us valuable insights into practice-changing updates in care. The topics include late-breaking clinical trials and science focusing on new drugs and device therapies.
DALLAS, 1er avril 2024 — Le Global Cardiovascular Research Funders Forum invite les chercheurs à participer à un nouveau défi d’analyse de données, sur la Precision Medicine Platform de l’American Heart Association (Association américaine du cœur). Ce.
SZN-043 showed evidence of target engagement, Wnt signal activation, and effects on liver function, supporting its advancement to a phase 1b trial in severe alcohol-associated hepatitis.
n this panel discussion, host Andrea Price MS, AACC brings together Holly Dalton, MSN, Joan Michaels, RN, AACC, and Bailey Estes MSN, AGNP-C, to explore best practices related to structural heart disease. In this episode, the focus is on quality in structural heart.
Topline results from AURORA indicate that while bitopertin significantly reduced PPIX levels, improvements in light tolerance were not statistically significant.
There is unmet need for additional biomarkers to better select patients with non–small cell lung cancer (NSCLC) that are likely to benefit from immunotherapy in order to improve patient outcomes, reduce patient toxicity, and relieve the growing burden of healthcare costs. In this issue of the JCI, Hayashi and colleagues evaluated soluble forms of the immune checkpoint molecules PD-L1, PD-1, and CTLA-4 in the plasma of patients with advanced NSCLC who had been treated with anti-PD-1/L1 therapy.
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are increasingly recognized for their role in reducing the risk and improving the prognosis of heart failure (HF). However, the precise mechanisms involved re.
Acute Type A aortic dissection (ATAAD) is a life-threatening cardiovascular disease associated with high mortality rates, where surgical intervention remains the primary life-saving treatment. However, the mor.
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