Tue.Apr 16, 2024

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Only One Harm From mRNA COVID Vaccines, Report Determines

Med Page Today

(MedPage Today) -- Independent reviewers confirmed a causal relationship between the first mRNA COVID-19 vaccines and myocarditis, and also determined that, more broadly, intramuscular shots can cause a series of shoulder injuries. At the same.

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FDA Approves Ustekinumab-aekn for PsO, PsA

HCPLive

The FDA approved ustekinumab-aekn for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis.

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Around 10% of Deaths from Coronary Stenting, Balloon Angioplasty are Preventable

DAIC

Getty Images milla1cf Tue, 04/16/2024 - 12:43 April 16, 2024 — Each year more than 500,000 Americans undergo percutaneous coronary intervention , or PCI, a minimally invasive procedure to unclog the arteries that feed the heart. While PCI, which includes both angioplasty and stenting, is one of the most common operations in the world, it does carry a small (about 1-2%) but significant risk of death.

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Analysis Suggests Causal Link Between AMD, Rheumatoid Arthritis

HCPLive

Mendelian randomization analysis demonstrated a direct connection between rheumatoid arthritis and an increased risk of age-related macular degeneration.

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Vivasure Medical Announces First Large Hole Venous Patient Treated with PerQseal Elite Vascular Closure System

DAIC

milla1cf Tue, 04/16/2024 - 12:40 April 16, 2024 — Vivasure Medical , a company pioneering novel fully absorbable technology for percutaneous vessel closure, today announced it has treated the first large bore venous patient with the PerQseal Elite vascular closure system, a sutureless and fully bioresorbable large-bore vessel closure device. The first successful implant was completed by Prof.

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Psoriasis Severity Index Scores Impacted by Tobacco Smoking in Current, Former Smokers

HCPLive

In this analysis, the study investigators highlighted the impact of smoking cigarettes on PASI 75 achievement.

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CVRx Announces Availability of Additional Data Supporting Long-term Benefits of Barostim

DAIC

milla1cf Tue, 04/16/2024 - 12:35 April 16, 2024 — CVRx, Inc., a commercial-stage medical device company, announced today the availability of additional data, including the publication of results of the post-market phase of the BeAT-HF trial in the European Journal of Heart Failure. These data highlight long-term sustained benefits of Barostim in heart failure patients with reduced ejection fraction.

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Olezarsen Shows Ability to Reduce Triglycerides for Patients with FCS in BALANCE Trial

HCPLive

Olezarsen shows promise in managing familial chylomicronemia syndrome, reducing triglycerides and acute pancreatitis events.

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Lp(a) and CV Risk Reduction With Icosapent Ethyl

American College of Cardiology

What is the cardiovascular (CV) benefit of icosapent ethyl (IPE) across a range of lipoprotein(a) [Lp(a)] levels?

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Polypills can reduce cardiovascular mortality by 11%: Study

Becker's Hospital Review - Cardiology

Polypills for atherosclerotic cardiovascular disease reduced all-cause mortality by 11% and risk of fatal and nonfatal cardiovascular events by 29%, a recent study found.

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Jonathan Barratt, MD: PROTECT Subgroup Analyses Continue to Favor Sparsentan for IgAN

HCPLive

Barratt discusses results from subgroup analyses of the phase 3 PROTECT trial based on baseline proteinuria and what they add to previous findings.

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MAC Attacks: Unusual Complications of Mitral Annular Calcification

American College of Cardiology

Mitral annular calcification (MAC) is common in the setting of chronic kidney disease and aging. Previously presumed "degenerative" in etiology, cardiac/vascular calcification is now understood to be inflammatory, involving osteoblastic transformation of myofibroblasts.

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Children with Sleep Disorders Have Double the Odds of Increased Health Care Usage

HCPLive

A new study explored increased health care utilization of children among several specific sleep disorders, race, and age.

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The Future of Cardiology - Value-Based Care, Private Equity and the Practice Landscape

American College of Cardiology

In this interview, Jerry Blackwell MD, MBA, FACC and Joseph E. Marine MD, MBA, FACC, discuss The Future of Cardiology - Value-Based Care, Private Equity and the Practice Landscape.

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Clopidogrel vs DAPT in Acute Coronary Syndromes and High Ischemic/Bleeding Risk

JAMA Cardiology

This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.

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Heartificial intelligence: in what ways will artificial intelligence lead to changes in cardiology over the next 10 years

The British Journal of Cardiology

Artificial intelligence (AI) will revolutionise cardiology practices over the next decade, from optimising diagnostics to individualising treatment strategies. Moreover, it can play an important role in combating gender inequalities in cardiovascular disease outcomes. There is growing evidence that AI algorithms can match humans at echocardiography analysis, while also being able to extract subtle differences that the human eye cannot detect.

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Leveraging Technology in Medical Education: A Vital Tool for Doctors Across Specialties

ADN Center of Excellence

In the ever-evolving landscape of medical education, technology has emerged as a powerful ally, revolutionizing the way doctors across various fields of medicine learn, practice, and stay updated. This digital transformation has not only enhanced the efficiency and effectiveness of medical education but has also addressed several challenges faced by healthcare professionals.

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Bleeding sites and treatment strategies for cardiac tamponade by catheter ablation requiring thoracotomy: risks of catheter ablation in patients with left atrial diverticulum

Journal of Cardiothoracic Surgery

There is insufficient information regarding the bleeding sites and surgical strategies of cardiac tamponade during catheter ablation for atrial fibrillation (AF).

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Leveraging Technology in Medical Education: A Vital Tool for Doctors Across Specialties

ADN Center of Excellence

In the ever-evolving landscape of medical education, technology has emerged as a powerful ally, revolutionizing the way doctors across various fields of medicine learn, practice, and stay updated. This digital transformation has not only enhanced the efficiency and effectiveness of medical education but has also addressed several challenges faced by healthcare professionals.

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Relationship between pan-immune- inflammation value and in major cardiovascular and cerebrovascular events in stable coronary artery disease patients undergoing on-pump coronary artery bypass graft surgery

Journal of Cardiothoracic Surgery

In this study, we aimed to evaluate the association of pan-immune-inflammation value (PIV) with major cardiovascular and cerebrovascular events (MACCE) in stable coronary artery disease patients undergoing on-.

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Tocilizumab-aazg Officially Launches in the US for Chronic Autoimmune Diseases

HCPLive

Fresenius announced the immediate availability of its tocilizumab biosimilar, tocilizumab-aazg (Tyenne), in the US.

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Heparin-induced DRESS syndrome in a paediatric patient and successful anaesthetic management in cardiovascular bypass surgery: case report

Journal of Cardiothoracic Surgery

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome is a severe adverse drug reaction marked by delayed hypersensitivity reactions causing skin and systemic complications. DRESS diagnosis is.

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Treat-and-Extend Regimen Superior in First Year of DME Treatment

HCPLive

A proactive treat-and-extend protocol yields superior results with fewer visits than a less intensive regimen in the first year of treatment for DME.

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FDA Advisors' COIs; Ongoing Ukraine Heart Transplants; N.J. Cardiologist's $2M Fraud

Med Page Today

(MedPage Today) -- It turns out the FDA advisory committee charged with reviewing the TriClip G4 had multiple financial ties to Abbott, the device manufacturer, creating a question of potential conflicts of interest (COI). (KFF Health News) FDA.

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Perspectives on Retinal Fluid Management

HCPLive

Experts discuss the importance of fluid management, presenting a range of perspectives on managing complex cases.

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Molecular mechanisms and potential therapeutic targets in the pathogenesis of hypertension in visceral adipose tissue induced by a high-fat diet

Frontiers in Cardiovascular Medicine

BackgroundHypertension (HTN) presents a significant global public health challenge with diverse causative factors. The accumulation of visceral adipose tissue (VAT) due to a high-fat diet (HFD) is an independent risk factor for HTN. While various studies have explored pathogenic mechanisms, a comprehensive understanding of impact of VAT on blood pressure necessitates bioinformatics analysis.MethodsDatasets GSE214618 and GSE188336 were acquired from the Gene Expression Omnibus and analyzed to ide

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Perspectives on Loading Dose Recommendations for New Therapies

HCPLive

Experts discuss the practice of loading doses for newer agents and when they would consider this suitable for patients.

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A Case Report of Mycoplasma pneumoniae-induced fulminant myocarditis in a 15-year-old male leading to cardiogenic shock and electrical storm

Frontiers in Cardiovascular Medicine

Mycoplasma pneumoniae (M. pneumoniae) is a well-recognized pathogen primarily associated with respiratory tract infections. However, in rare instances, it can lead to extrapulmonary manifestations, including myocarditis. We present a case of a 15-year-old male who developed fulminant myocarditis, cardiogenic shock, and cardiac electrical storm attributed to M. pneumoniae infection.

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PTSD Emotional Numbing Impacts Intensity of Neutral to Negative State Shifts

HCPLive

A new study found individuals with PTSD face rapid transitions between neutral and negative emotional states.

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Atrial fibrillation and COVID-19: an analysis of the ambulatory database

Frontiers in Cardiovascular Medicine

Atrial fibrillation (AF) is the most common heart rhythm disorder in clinical practice. It worsens the quality of life of patients, leads to an increase in the mortality rate because of its association with a high risk of thromboembolic complications. The current pandemic of a new coronavirus infection, which began in March 2020, was marked by an increase in cardiovascular diseases, including an increase in the number of patients with AF.

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Trends in Targeted Temperature Management Before and After 2013, with José López, MD

HCPLive

An ACC.24 analysis found a decline in TTM use post-2013 TTM trial, which investigators suggest indicates a potential misinterpretation of trial findings.

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Difference Between a Biphasic and Monophasic Defibrillators

All About Cardiovascular System and Disorders

The direct current shock given can have a monophasic or biphasic waveform. In monophasic shock, the shock is given in only one direction from one electrode to the other. In a biphasic shock, initial direction of shock is reversed by changing the polarity of the electrodes in the latter part of the shock. Usually the initial voltage applied is higher than the reversed polarity shock.

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Catheter-Based Therapy for High- or Intermediate-Risk PE

American College of Cardiology

What are the in-hospital and readmission outcomes in patients with intermediate-risk or high-risk pulmonary embolism (PE) treated with versus without catheter-based therapies (CBTs) in a large retrospective registry?

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Fair Allocation of GLP-1 and Dual GLP-1–GIP Receptor Agonists

The New England Journal of Medicine

A shortage of GLP-1 receptor agonists and other drugs raises questions about how limited supplies should be allocated. A proposed framework could guide governments, professional societies, and physicians.

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Premature Ventricular Contractions: the Incidentalomas of Cardiac Electrophysiology?

HeartRhythm

An incidentaloma generally has two characteristics. First, it is observed as an unintended consequence of ordering a medical test. Second, the subsequent steps for optimal clinical care remain poorly elucidated. Might there be such a phenomenon relevant to cardiac electrophysiology? Two original research manuscripts in this issue of Heart Rhythm remind us that premature ventricular contractions (PVCs) sometimes represent an incidentaloma and sometimes are the prespecified target of scrutiny.

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Editors and Editorial Board

Journal of the American Heart Association

Journal of the American Heart Association, Volume 13, Issue 8 , April 16, 2024.

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Atrial Shunt Device Effects on Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction

JAMA Cardiology

This post hoc analysis of A Study to Evaluate the Corvia Medical Inc IASD System II to Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (REDUCE LAP-HF II) randomized clinical trial evaluates the long-term effects of an atrial shunt device on cardiac structure and function in patients with heart failure and preserved or mildly reduced ejection fraction.