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Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundThe effectiveness of statin use in preventing adverse cardiovascular events in individuals with atrial fibrillation (AF) has remained uncertain. This study aimed to assess whether statin use could lead to better outcomes among individuals with AF.Methods and ResultsWe enrolled 397 787 patients with AF from January 1, 2012 to December 31, 2020.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundEpicardial adipose tissue (EAT) accumulation is thought to play a role in the pathophysiology of heart failure (HF) with midrange ejection fraction and HF with preserved ejection fraction, but its effect on outcome is unknown.Methods and ResultsA total of 692 patients with HF with midrange ejection fraction or HF with preserved ejection fraction who underwent cardiovascular magnetic resonance at 2 medic
Orly Vardeny, PharmD, MS explores the efficacy of nonsteroidal MRAs in heart failure with mildly reduced or preserved ejection fraction in the FINE-ARTS trial.
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Relation of Nyquist limit to Pulse Repetition Frequency (PRF): A. Nyquist limit is half the pulse repetition frequency B. Nyquist limit is twice the pulse repetition frequency C. Nyquist limit is three times the pulse repetition frequency D. Nyquist limit is one third of the pulse repetition frequency Correct Answer: A. Nyquist limit is half the pulse repetition frequency Nyquist limit is the maximum velocity of blood flow that can be estimated by pulsed Doppler.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. Renal denervation (RDN) is recognized as an adjunct therapy for hypertension management with a favorable and consistent blood pressurelowering efficacy and safety profile. Alteration in medication burden is another noteworthy outcome of RDN for clinicians and patients.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. Renal denervation (RDN) is recognized as an adjunct therapy for hypertension management with a favorable and consistent blood pressurelowering efficacy and safety profile. Alteration in medication burden is another noteworthy outcome of RDN for clinicians and patients.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundA multidisciplinary approach improves guidelinedirected medical therapy in systolic heart failure (HF), but its efficacy in patients with HF due to cardiac sarcoidosis is unreported.Methods and ResultsIn a retrospective cohort study, we reviewed 848 patients from our institutional cardiac sarcoidosis clinics, identifying those with a cardiac sarcoidosis diagnosis, HF (left ventricular ejection fraction
Atrial fibrillation (AF) prediction improves by combining clinical scores with a polygenic risk score (PRS) for AF (AF-PRS), but there are limited studies of PRS for ventricular arrhythmia (VA) prediction.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundValvular heart disease poses an escalating global health challenge with an increasing impact on mortality and disability. This study aims to comprehensively analyze the global burden of valvular heart disease.Methods and ResultsUsing the Global Burden of Disease 2021 data, we analyzed the prevalence and disabilityadjusted life years, examining implications across demographics and geographic regions.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. Backgroundsecretase 1 (BACE1) plays a key role in amyloidogenic pathway and is considered a new mechanism for cerebral small vessel disease (CSVD). We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders an
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundAlthough a high pulse rate assessed in the clinic office setting has been associated with an increased risk of cardiovascular disease and mortality, there are few studies assessing the prognostic ability of outofoffice pulse rate, particularly selfmeasured home pulse rate.Methods and ResultsWe investigated the prognostic ability of home pulse rate in 3022 patients with mildtomoderate hypertension.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundDespite robust evidence supporting an association with improved outcomes in eligible patients, cardiac rehabilitation (CR) remains underused, with a minority of eligible patients participating. Virtual cardiac rehabilitation (VCR) has been proposed as an alternative to traditional centerbased CR (CBCR) to improve usage rates.
Journal of the American Heart Association, Volume 13, Issue 24 , December 17, 2024. BackgroundAlthough sex differences in coronary artery disease (CAD) risk have been observed, little is known about the role of sex hormones in CAD genetics. Accounting for sex hormone levels may help identify CADrisk loci and extend our knowledge of its genetic architecture.Methods and ResultsA total of 365 662 individuals of European ancestry enrolled in the UK Biobank were considered.
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