Wed.Apr 17, 2024

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Adults with congenital heart disease faced higher risk of abnormal heart rhythms

American Heart News - Heart News

Research Highlights: Almost 1 in 5 adults with congenital heart disease living in Israel had or developed an abnormal heart rhythm over five years. Adults with congenital heart disease who developed an irregular heart rhythm in the heart’s upper.

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Antipsychotics in Dementia Tied to Wider Range of 'Serious Harms'

Med Page Today

(MedPage Today) -- Use of antipsychotics in dementia patients was associated with an increased risk for a wider range of adverse outcomes than previously acknowledged, a population-based matched cohort study from the U.K. showed. In the analysis.

Dementia 119
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CPR-Therapeutics, Inc. Names Mike Black as Chief Strategy Officer

DAIC

Mike Black milla1cf Wed, 04/17/2024 - 16:15 April 17, 2024 — CPR Therapeutics, Inc. (CPR-T), an early-stage medtech startup funded by the N.I.H and N.S.F to develop the next generation technology for cardiopulmonary resuscitation, announced today that Mike Black will be advising the Company as its first Chief Strategy Officer. CPR Therapeutics, Inc. is developing multimodal cardiopulmonary resuscitation (CPR), a more effective form of automated mechanical CPR.

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Plant-Based Diet Intervention Improves Disease Activity, Symptoms in RA, Osteoarthritis

HCPLive

Participants described the intervention as complete and coherent and would recommend this intervention to other patients.

Diet 115
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Getinge Enters into Commercial Distribution Agreement with Cook Medical for iCast Covered Stent System in the United States

DAIC

milla1cf Wed, 04/17/2024 - 16:18 April 17, 2024 — Getinge and Cook Medical announced an exclusive sales and distribution agreement for the iCast covered stent system, which has been on the market for twenty years and recently received premarket approval for treatment of iliac arterial occlusive disease. The agreement includes a 60-day transition period after which Cook Medical will assume the sales, marketing and distribution rights for the product in the United States.

Stents 105
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Researchers find that accelerated aging biology in the placenta contributes to a rare form of pregnancy-related heart failure

Science Daily - Heart Disease

In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.

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Self-Monitoring of Urate Concentration Could Benefit Gout Management

HCPLive

Patient-led urate monitoring supports adherence to urate-lowering therapy and helps attain target concentrations among individuals with gout.

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International Consensus Statement Calls for Prioritization of Kidney Disease by the WHO

HCPLive

The consensus calls for the recognition of kidney disease as a major non-communicable disease driver of premature mortality by the World Health Organization.

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To repair or to replace in mitral valve infective endocarditis? an updated meta-analysis

Journal of Cardiothoracic Surgery

Valve infective endocarditis (IE) is a potentially life-threatening condition that affects patients’ livelihoods. Current surgical options in mitral valve IE include mitral valve repair (MVr) or replacement (M.

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NSAIDs Decreased the Odds of Adverse Cardiovascular Events in Gout

HCPLive

NSAID use decreased the odds of a cardiovascular event by 12% in patients with gouts

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Aortic Coarctation

The New England Journal of Medicine

A 35-year-old man received an incidental diagnosis of hypertension during a routine medical assessment. Computed tomographic angiography revealed aortic coarctation.

Aortic 69
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Tirzepatide Shows Benefit in Obstructive Sleep Apnea, SURMOUNT-OSA Trial

HCPLive

Topline data from the SURMOUNT-OSA studies provide insight into the effects of tirzepatide in OSA with obesity, with Lilly disclosing plans for a regulatory submission mid-year.

Obesity 69
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Busting common myths about caffeine

Physiologically Speaking

Caffeine — it’s one hell of a drug. Also known as 1, 3, 7-trimethylxanthine, caffeine is one of the most well-understood substances in terms of its effect on our brain and body. It’s also one of the most used drugs in the world. For most people, caffeine has an ergogenic (performance-enhancing) effect. It can help increase your strength, endurance, and reaction time, among other benefits.

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Psoriasis Patients with Arthralgia At Increased Risk of Psoriatic Arthritis Development

HCPLive

In this analysis, investigators sought to assess PsA development probability in subclinical PsA as well as to characterize symptoms and patterns of subclinical PsA.

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Aprocitentan, a Newly Approved Drug for Resistant Hypertension

NEJM Journal Watch - Cardiology

This drug is the first endothelin-receptor antagonist approved to treat patients with systemic hypertension.

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Visual Impairment Associated with Heightened Risk of Suicidal Tendencies

HCPLive

Vision issues were linked to an increased risk of suicidal ideation, suicidal behavior, and suicide death, particularly among adolescents.

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Gender differences in the relationship between serum uric acid and the long-term prognosis in heart failure: a nationwide study

Cardiovascular Diabetology

Serum uric acid (SUA) is an important pathogenetic and prognostic factor for heart failure (HF). Gender differences are apparent in HF. Furthermore, gender differences also exist in the association between SUA.

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TNF Inhibitors Linked to Greater Risk of Progressive eGFR Decline in Patients with IBD

HCPLive

Incident use of anti-TNF therapy was linked to an increased risk of kidney function decline but not all-cause mortality in patients with newly diagnosed IBD.

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Cedars-Sinai Detects AFib with Echo AI

CardiacWire

A Cedars-Sinai-led team developed an echocardiography AI model that accurately detects patients with atrial fibrillation – including asymptomatic patients – potentially revealing a new “opportunistic screening” method to drive earlier AFib detection and treatment. Transthoracic echo (TTE) is the most common cardiovascular imaging exam, and is increasingly being combined with AI to support image acquisition, interpretation, and reporting.

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Diabetes Dialogue: STEP HFpEF DM and Fair Allocation of Incretin-Based Therapies

HCPLive

In this episode, hosts discuss the STEP HFpEF DM trial and the need for fair allocation of incretin-based therapies with ongoing shortages and overwhelming demand.

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FDA Update: Heartmate II and Heartmate 3 LVAS Recalled Due to Obstruction

American College of Cardiology

The U.S. Food and Drug Administration (FDA) announced on April 15 that Abbott/Thoratec Corp. is recalling the Heartmate II and Heartmate 3 Left Ventricular Assist System (LVAS) due to long-term buildup of biological material causing an obstruction in the device, making it more difficult for the heart to pump blood.

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Secukinumab 300 mg May Improve PsA or Active Psoriasis More Than 150 mg

HCPLive

A pooled analysis revealed a loading-dose regimen, especially for patients receiving secukinumab 150 mg for PsA, increases the odds of disease improvement.

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SGLT2 Inhibitors and Major Adverse CV Outcomes

American College of Cardiology

What is the effect of sodium glucose co-transporter 2 inhibitors (SGLT2i) on the risk of major adverse cardiovascular events (MACE) and its individual components, overall and within clinically relevant subgroups of patients, irrespective of atherosclerotic cardiovascular disease (ASCVD), diabetes, and kidney function?

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Longitudinal blood glucose level and increased silent myocardial infarction: a pooled analysis of four cohort studies

Cardiovascular Diabetology

Fasting glucose (FG) demonstrates dynamic fluctuations over time and is associated with cardiovascular outcomes, yet current research is limited by small sample sizes and relies solely on baseline glycemic lev.

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Robotic Bronchoscopy - Managing Sub-Centimeter Lung Cancer Tumors Together

Society of Thoracic Surgeons - Allied Health

Webinar Robotic Bronchoscopy - Managing Sub-Centimeter Lung Cancer Tumors Together cgolden Wed, 04/17/2024 - 10:49 May 9, 2024 Webinar Link: Register for Free In part two of the Robotic Thoracic Surgery webinar series, experts will discuss how a collaborative thoracic and pulmonary robotic approach is expanding thoracic oncology. Through increased lung cancer screening and incidental pulmonary nodule programs, the management of 8-10 mm pulmonary nodules in high-risk patients has come to the fore

Cancer 52
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Complete resection of a giant intrapericardial cardiac synovial sarcoma

Journal of Cardiothoracic Surgery

Synovial sarcoma of the heart is a rare tumor. Herein we would like to report a case of giant intrapericardial cardiac synovial sarcoma that originated from the right ventricle and grew outward near the diaphr.

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What are the Cyanotic Congenital Heart Diseases with Increased Pulmonary Blood Flow?

All About Cardiovascular System and Disorders

D-Transposition of great arteries Double outlet right ventricle without pulmonary pulmonary stenosis Taussig-Bing anomaly Total anomalous pulmonary venous return Truncus arteriosus Single ventricle (double inlet ventricle, univentricular heart)

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Reconstruction method for massive lateral chest wall sarcoma using titanium plates and mesh: a case report

Journal of Cardiothoracic Surgery

Very large chest wall resections can lead to acute thoracic insufficiency syndrome due to the interdependence of lung expansion and thoracic volume. Chest wall tumor surgeries often encounter complications, wi.

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Global research trends and emerging opportunities for integrin adhesion complexes in cardiac repair: a scientometric analysis

Frontiers in Cardiovascular Medicine

ObjectiveCardiac regenerative medicine has gained significant attention in recent years, and integrins are known to play a critical role in mediating cardiac development and repair, especially after an injury from the myocardial infarction (MI). Given the extensive research history and interdisciplinary nature of this field, a quantitative retrospective analysis and visualization of related topics is necessary.Materials and methodsWe performed a scientometric analysis of published papers on card

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Antithrombotic drug removal with hemoadsorption during off-pump coronary artery bypass grafting

Journal of Cardiothoracic Surgery

Patients requiring coronary artery bypass grafting (CABG) are often loaded with antithrombotic drugs (AT) and are at an increased risk for perioperative bleeding complications. Active AT removal by a hemoadsor.

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What are the Cyanotic Congenital Heart Diseases With Decreased Pulmonary Blood Flow?

All About Cardiovascular System and Disorders

Tetralogy of Fallot TOF with pulmonary atresia Pulmonary atresia with intact interventricular septum Tricuspid atresia Double outlet right ventricle Transposition of great arteries with ventricular septal defect and pulmonary stenosis Ebstein’s anomaly of tricuspid valve In DORV and tricuspid atresia, there are also variants with increased pulmonary blood flow, in the absence of associated pulmonary stenosis.

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Massive retroperitoneal hematoma caused by intercostal artery bleeding after blunt trauma: a case report

Journal of Cardiothoracic Surgery

Background The occurrence of massive retroperitoneal hematoma caused by intercostal artery bleeding is exceedingly uncommon. Case presentation A middle-aged male presented to the hospital after a fall. Computed tomography scan revealed a massive retroperitoneal hematoma without any evidence of organ or major vessel rupture. The angiogram revealed extravasation from a branch of the twelfth intercostal artery, and successful transcatheter arterial embolization was performed on this specific artery

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What are the acyanotic congenital heart diseases with left to right shunt lesions?

All About Cardiovascular System and Disorders

Atrial septal defect – Ostium Primum, Ostium Secundum, Sinus Venosus Partial anomalous pulmonary venous return Atrioventricular septal defect Ventricular septal defect – inlet, outlet, perimembranous, muscular Patent ductus arteriosus Aortopulmonary window Coronary artery fistula draining to right heart Ruptured sinus of Valsalva aneurysm to right heart

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Long term outcomes of bioprosthetic valves in the mitral position: A pooled meta- analysis of reconstructed time-to-event individual patient data

The American Journal of Cardiology

Publication date: Available online 16 April 2024 Source: The American Journal of Cardiology Author(s): Marinos Koulouroudias, Michele Di Mauro, Giovanni Chiariello, Paolo Meani, Roberto Lorusso

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Ventricular Tachycardia Management

All About Cardiovascular System and Disorders

Ventricular tachycardia is a potentially life threatening cardiac arrhythmia. If the rate is very fast, hemodynamic deterioration can occur rapidly. On the ECG, ventricular tachycardia can be defined as three or more ventricular ectopic beats occurring in a sequence at a rate more than 100 per minute. Ventricular tachycardia which gets spontaneously terminated within 30 seconds is called non sustained ventricular tachycardia (NSVT).

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Genotype-First Approach to Cardiomyopathy Outcomes

American College of Cardiology

What is the risk of mortality and composite cardiomyopathy-related outcomes associated with predicted deleterious variants in cardiomyopathy-associated genes?

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Commotio cordis

All About Cardiovascular System and Disorders

Sometimes a player drops down dead after being accidentally hit by a ball or another player. This situation which can occur in any contact sports is known as commotio cordis. The sudden hit on the chest causes the heart to stop in ventricular fibrillation. Ventricular fibrillation is a very fast irregular electrical activity of the lower chambers which prevents proper contraction of the heart.