Mon.Apr 22, 2024

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Neurotechnology Development Must Be Slow and Steady

Med Page Today

(MedPage Today) -- Through my work as a neuroscientist who designs neural implants to monitor the injured brain after severe traumatic brain injuries, stroke, and brain cancers, it has become very clear to me that my field needs to communicate.

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Black and Hispanic people in the United States growing more confident learning and performing CPR

American Heart News - Heart News

DALLAS, April 22, 2024 — More Black and Hispanic people in the U.S. feel confident performing Cardiopulmonary Resuscitation (CPR). A 2023 American Heart Association survey found that 44% of Black Americans now feel confident in performing.

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Chest pain, resolved. Does it need emergent cath lab activation (some controversy here)? And much much more.

Dr. Smith's ECG Blog

A 50-something male with hypertension and 20- to 40-year smoking history presented with 1 week of stuttering chest pain that is worse with exertion, which takes many minutes to resolve after resting and never occurs at rest. It is a ssociated with mild dyspnea on exertion. At times the pain does go to his left neck. It was present on arrival at triage but then resolved before bed placement in the ED.

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Assessing Headaches in Hospitalized Patients, with Stephanie Nahas, MD, MSEd

HCPLive

Nahas reviews key highlights from her session at ACP, emphasizing the importance of reviewing patient history and considering what other factors may be causing headaches.

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Ozempic Hiatus Before Surgery: Is a Weeklong Pause Really Needed?

Med Page Today

(MedPage Today) -- Continued use of a glucagon-like peptide 1 (GLP-1) receptor agonist leading up to surgery may not increase the risk for regurgitation and pulmonary aspiration during operations after all, an analysis of insurance claims data.

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RCE Technologies, Inc. Announces First-In-Human Transdermal Continuous Cardiac Biomarker Monitoring

DAIC

RCE Technologies, Inc. (RCE) is an innovative artificial intelligence (AI) based medical technology company dedicated to early heart attack detection. milla1cf Mon, 04/22/2024 - 15:05 April 22, 2024 — At the annual American College of Cardiology conference ( ACC.24 ) in Atlanta last week, RCE Technologies, Inc. , (RCE), an innovative artificial intelligence (AI) based medical technology company dedicated to early heart attack detection, highlighted results of a pilot study enrolling cardiac cat

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Predicting cardiac arrhythmia 30 minutes before it happens

Science Daily - Heart Disease

Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal. Researchers have recently developed a deep-learning model capable of predicting the transition from a normal cardiac rhythm to atrial fibrillation.

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Prolonged Medical Fasting May Benefit Pain Symptoms in Fibromyalgia

HCPLive

Prolonged modified fasting, in a multimodal medical approach, may help patients with fibromyalgia improve pain and psychosomatic symptoms.

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Efficacy and Safety of Dapagliflozin in Acute Heart Failure

American College of Cardiology

The goal of the DICTATE-AHF trial was to determine the efficacy and safety of adding the sodium-glucose cotransporter-2 (SGLT2) inhibitor dapagliflozin to intravenous (IV) loop diuretic therapy in patients hospitalized with acute decompensated heart failure (ADHF).

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A Rising Tide: The Impact of Climate Change on Allergic Disease

HCPLive

Cerceo, Peden, and Ziska joined HCPLive to speak on the imminent threat posed by climate change, highlighting the impact especially on individuals with allergic disease.

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Reinterventions After TAVR or SAVR for Severe Aortic Stenosis

American College of Cardiology

What is the 5-year incidence of valve reintervention after self-expanding CoreValve/Evolut transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR)?

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1 in 3 Older Adults Reported Using an Alternate Health Care Site

HCPLive

A poll found people were more likely to use alternate health care sites if they were women, aged 50 – 64 over 65 – 80 years, and had a household income of < $60,000.

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Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 April 2024; doi:10.1038/s41569-024-01032-y According to data from the IMPROVE-HCM trial, ninerafaxstat is well tolerated by patients with symptomatic non-obstructive hypertrophic cardiomyopathy and improves exercise performance among those who are most symptomatically limited.

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Risankizumab Significantly Improves Skin, Joint Symptoms in PsA

HCPLive

Post-treatment with risankizumab, the cDAPSA score, PGA score, and PASI score substantially decreased among a cohort of patients with psoriatic arthritis.

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Doc Killed in Murder-Suicide? New Human Bird-Flu Case; Olympics' Eating Disorders

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Marsha Certain, MD, an interventional cardiologist from Georgia, was killed late last week, at age 69, in an apparent murder-suicide, according to authorities.

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Afib more common and dangerous in younger people than previously thought, study finds

Science Daily - Heart Disease

Atrial fibrillation (Afib), a common type of arrhythmia that is on the rise in people under the age of 65, is more dangerous in this increasingly younger population than previously thought, according to new research.

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Diagnosis and Management of Cardiac Sarcoidosis: Key Points

American College of Cardiology

The following are key points to remember from an American Heart Association (AHA) scientific statement on the diagnosis and management of cardiac sarcoidosis (CS).

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Mean computed tomography value to predict spread through air spaces in clinical N0 lung adenocarcinoma

Journal of Cardiothoracic Surgery

The aim of this study was to assess the ability of radiologic factors such as mean computed tomography (mCT) value, consolidation/tumor ratio (C/T ratio), solid tumor size, and the maximum standardized uptake.

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Multi-Valve Surgery Risk Calculator

Society of Thoracic Surgeons - Congenital

Resource Multi-Valve Surgery Risk Calculator kchalko Mon, 04/22/2024 - 14:57 The expanding use of transcatheter valve technologies has changed the landscape in the treatment of valvular disease. Valve surgery is rapidly shifting to more complex scenarios that involve multiple valve interventions and concomitant procedures. STS leveraged contemporary national data from the STS Adult Cardiac Surgery Database between July 2017 and December 2023 to analyze outcomes of 32,938 patients that underwent

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Diagnostic and prognostic value of plasma miR-106a-5p levels in patients with acute heart failure

Journal of Cardiothoracic Surgery

It is essential to find reliable biomarkers for early diagnosis and prognosis of acute heart failure (AHF) for its mitigation. Currently, increasing attention is paid to the role of microRNAs (miRNAs/miRs) as.

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RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 April 2024; doi:10.1038/s41569-024-01034-w Three randomized clinical trials presented at ACC.24 demonstrate that olezarsen and plozasiran, RNA-based therapies that target APOC3, can robustly reduce plasma triglyceride levels in patients with moderate to severe hypertriglyceridaemia.

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Intraoperative central venous pressure during cardiopulmonary bypass is an alternative indicator for early prediction of acute kidney injury in adult cardiac surgery

Journal of Cardiothoracic Surgery

The relationship between venous congestion in cardiopulmonary bypass (CPB) and acute kidney injury (AKI) in cardiac surgery has not utterly substantiated. This study aimed at investigate the relationship betwe.

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Heart pump increases survival in STEMI-related cardiogenic shock

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 April 2024; doi:10.1038/s41569-024-01035-9 Data from the DanGer Shock trial demonstrate that implantation of a microaxial flow pump in patients with ST-segment elevation myocardial infarction complicated by cardiogenic shock increases the survival rate compared with standard care alone.

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Differentiating Medication Non-Adherence From Underlying Comorbidities

HCPLive

The expert panel addresses the common assumption of medication non-adherence in patients with resistant diabetes, provides strategies to differentiate non-adherence from underlying comorbidities contributing to resistance, and discusses the challenges of patients who are post-metabolic surgery, yet experience weight gain and symptom recurrence.

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Case Report: Right aortic arch with isolation of left brachiocephalic artery and ventricular septal defect

Frontiers in Cardiovascular Medicine

Right aortic arch with isolation of left brachiocephalic artery is a rare congenital aortic arch anomaly. Herein, we reported a case of this rare anomaly with ventricular septal defect in a 9-month-old infant. We successfully reconstructed the islolated left brachiocephalic artery and repaired the ventricular septal defect in one stage.

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Defining Resistant Diabetes

HCPLive

Hanford Yau, MD, Ralph DeFronzo, MD, Pam Kushner, MD, Honey East, MD, and Christopher Lucci, MD, explore resistant diabetes, share their clinical experience regarding the frequency of this condition, and highlight the role of continuous glucose monitoring in identifying patients who may be resistant, as indicated by prolonged periods of blood glucose levels outside the target range.

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Expedited transfer to cardiac arrest center vs standard care for non-ST elevation out-of-hospital cardiac arrest

Cardiology Update

In a prospective, multicentre, parallel, randomised clinical trial titled ARREST, researchers aimed to evaluate the effectiveness of expedited transfer to a cardiac arrest center compared to standard care following out-of-hospital cardiac arrest. The ARREST study is the first randomized trial of its kind. Conducted in the UK, the study enrolled 862 patients aged 18 or older who experienced return of spontaneous circulation after cardiac arrest without ST elevation.

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What is the link between thyroid and heart disease?

All About Cardiovascular System and Disorders

Heart disease can occur with both increased function of the thyroid gland and decreased function of the thyroid gland. When thyroid function is increased, heart rate increases and the work load of the heart increases. In severe cases heart failure may occur. A peculiarity of heart failure associated with increased thyroid function is that it is a high output failure unlike the usual heart failure in which the pumping function of the heart is reduced, and low output failure occurs.

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Subcutaneous Vedolizumab Approved for Moderate-to-Severe Crohn Disease

HCPLive

Announced on April 18, the approval is based on the VISIBLE 2 trial and comes less than 7 months after the approval of SC vedolizumab in ulcerative colitis.

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Operator and Centre Characteristics, And Choice of Pacing Mode

HeartRhythm

Single- or dual-chamber devices may be implanted in patients requiring a permanent pacemaker (PPM) with a preserved left ventricular ejection fraction and without permanent atrial fibrillation (AF). Although studies have failed to show a mortality benefit of dual- over single-chamber pacing, dual-chamber pacing is associated with lower risks of AF and pacemaker syndrome.

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Kelley Branch, MD: Antithrombotics in Primary, Secondary Prevention of Cardiovascular Disease

HCPLive

Branch discusses key takeaways from his session at ACP and guideline recommendations for primary and secondary prevention of cardiovascular disease.

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Clinical Performance of Mechanical Aortic Valve Prostheses

American College of Cardiology

Is there a difference in clinical performance between different bileaflet mechanical aortic valve prostheses?

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More Than Half of RA Patients Achieve Remission After Upadacitinib 15 mg

HCPLive

An extension study showed upadacitinib 15 mg and 30 mg for rheumatoid arthritis continues to be favorable, with many patients achieving remission.

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Predicting Post-Infarct Ventricular Tachycardia by Integrating Cardiac MRI and Advanced Computational Reentrant Pathway Analysis

HeartRhythm

Implantable cardiac defibrillator (ICD) implantation can protect against sudden cardiac death (SCD) after a myocardial infarction. However, improved risk stratification for device requirement is still needed.

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Early Adherence to Glaucoma Medication Predicts Future Treatment Patterns

HCPLive

The national registry-based analysis in Denmark may inform the clinical value of medication adherence in the first years of glaucoma treatment.

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Prediction of severe ventricular arrhythmias in mitral valve prolapse patients by exercise ECG

HeartRhythm

Mitral valve prolapse (MVP) is a common condition (prevalence 2-3 %)1, with a good prognosis. However, some MVP patients experience severe ventricular arrhythmias (VA). Identifying patients at risk is challenging and evidence is sparse. The predictive role of exercise testing in MVP has not been investigated. We aimed to explore whether exercise ECG could predict subsequent severe VA in MVP patients.

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Anne Thorndike, MD, MPH: Discussing Treatment Approaches for Patients with Obesity

HCPLive

Thorndike discussed highlights from her ACP 2024 talk titled ‘Annals Beyond the Guidelines: How Would You Treat this Patient with Obesity?

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