Cardiology Update

MARCH 17, 2024

Childhood-onset cardiomyopathies represent a rare and poorly understood subset of cardiac disorders. In a recent study published in the European Heart Journal, investigators delved into the demographics and prognosis of pediatric cardiomyopathy patients within the inaugural European Cardiomyopathy Registry. Data were prospectively gathered from individuals aged 1 to under 18 years participating in the European Society of Cardiology EURObservational Research Programme Cardiomyopathy and Myocardit

Cardiomyopathy 119

Cardiomyopathy Pediatrics Article Research 119

Cardiovascular Diabetology

MARCH 17, 2024

The cumulative effect of postpartum weight retention from each pregnancy in a woman’s life may contribute to her risk of ultimately developing type 2 diabetes and cardiovascular disease. However, there is limi.

Cardiovascular Disease 105

Cardiovascular Disease Diabetes Research 105

HCPLive

MARCH 17, 2024

After 5 years, laparoscopic Roux-en-Y gastric bypass cured OSA in 55.1% of patients, and only 20% of patients still had moderate or severe OSA.

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Cardiovascular Diabetology

MARCH 17, 2024

Randomized controlled trials and real-world studies suggest that combination therapy with sodium–glucose transport protein 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) is ass.

Diabetes 98

Diabetes Research 98

Heart Sisters

MARCH 17, 2024

Here’s my take on what can happen when academics, journal editors, and medical conference organizers tell us they welcome patient partners.

Academic 97

Academic Heart Disease Research 97

Cardiovascular Diabetology

MARCH 17, 2024

There is a paucity of contemporary data on the prevalence and prognostic significance of cardiac autonomic neuropathy (CAN) from community-based cohorts with type 2 diabetes assessed using gold standard method.

Diabetes 98

Diabetes Research 98

Medical Xpress - Cardiology

MARCH 17, 2024

By harnessing light, my colleagues and I designed a wireless, ultrathin pacemaker that operates like a solar panel. This design not only eliminates the need for batteries but also minimizes disruptions to the heart's natural function by molding to its contours. Our research, recently published in the journal Nature, offers a new approach to treatments that require electrical stimulation, such as heart pacing.

Pacemaker 89

Pacemaker Research 89

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page 963-966, March 19, 2024.

Tachycardia 73

Tachycardia Circulation 73

Nature Reviews - Cardiology

MARCH 17, 2024

Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-01015-z In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associated with an increased risk of death or major cardiovascular events compared with patients in whom microplastics and nanoplastics were not detected.

Plaque 69

Plaque 69

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page 899-901, March 19, 2024.

Heart Failure 67

Heart Failure Circulation 67

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Backgrounds Cuprotosis is a newly discovered programmed cell death by modulating tricarboxylic acid cycle. Emerging evidence showed that cuprotosis-related genes (CRGs) are implicated in the occurrence and progression of multiple diseases. However, the mechanism of cuprotosis in heart failure (HF) has not been investigated yet. Methods The HF microarray datasets GSE16499, GSE26887, GSE42955, GSE57338, GSE76701, and GSE79962 were downloaded from the Gene Expression Omnibus (GEO) database to ident

Heart Failure 64

Heart Failure Biomarkers Download 64

Nature Reviews - Cardiology

MARCH 17, 2024

Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-01001-5 Non-coding RNAs are implicated in the pathophysiology of ischaemic heart disease and heart failure. In this Review, Caporali and colleagues examine the biology of these molecules and discuss the potential of non-coding RNAs for translation to the clinic as biomarkers and therapeutics in adverse cardiac remodelling leading to ischaemic heart failure.

Biomarkers 63

Biomarkers Heart Disease Heart Failure 63

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Background Refractory angina (RA) is a chronic condition characterized by the presence of debilitating angina symptoms due to established reversible ischemia in the presence of obstructive coronary artery disease (CAD). Treatments for this condition have undergone major developments in recent decades; however, the treatment for RA remains a challenge for medicine.

Angina 64

Angina Quality of Life Coronary Artery Disease Ischemia 64

Nature Reviews - Cardiology

MARCH 17, 2024

Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-01012-2 In this Tools of the Trade article, Trivett discusses the potential of long-read sequencing in generating high-quality reference genomes of animal models of cardiovascular disease.

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Article Cardiovascular Disease 61

Cardiovascular Diabetology

MARCH 17, 2024

Hemorrhagic stroke (HS), including non-traumatic intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), constitutes a substantial proportion of cerebrovascular incidents, accounting for around 30% o.

Hemorrhage 52

Hemorrhage Stroke Strokes Research 52

Nature Reviews - Cardiology

MARCH 17, 2024

Nature Reviews Cardiology, Published online: 18 March 2024; doi:10.1038/s41569-024-00998-z Protein glycosylation is vital to the regulation of cell function, and changes in this post-translational modification underlie many disease processes. In this Review, Chatham and Patel discuss how protein glycosylation contributes to normal cardiovascular function and its role in cardiovascular disease, identifying important knowledge gaps and areas for future research.

Cardiovascular Disease 52

Cardiovascular Disease Research 52

All About Cardiovascular System and Disorders

MARCH 17, 2024

Here is the transcript of the video: Now we will have an ECG, focusing mainly on the rhythm analysis. That is what we are going to see. Clinical history is currently not available, let us see, what we can make out from the ECG. If you have a look at this ECG, sometimes, in this region, you may pass off it as just a low normal heart rate with nothing else.

Tachycardia 52

Tachycardia Congenital General Cardiology 52

CTVS

MARCH 17, 2024

It’s hard to believe that every six minutes someone dies from a blood clot here in the United States. Blood clots are gel-like masses that form inside your arteries or veins anywhere in the body.

Blood Clot 52

Blood Clot Cardiothoracic Thrombosis 52

All About Cardiovascular System and Disorders

MARCH 17, 2024

Here is the transcript of the video: Implantable defibrillator is an important life saving device. It can automatically detect life threatening ventricular arrhythmias and treat them, either with a shock or, sometimes by overdrive pacing. Then, why is it mentioned that, implanting a defibrillator soon after an acute myocardial infarction, in those with left ventricular dysfunction and prone for ventricular arrhythmias and sudden cardiac death, is not useful?

Myocardial Infarction 52

Myocardial Infarction Defibrillator Sudden Cardiac Death Arrhythmia 52

Dr. Paddy Barrett

MARCH 17, 2024

" I wish I did this 10 years ago ". This is probably one of the most common things I hear when I take someone through the process of understanding and reducing their risk of heart disease. Far too often, I meet people with advanced heart disease who really wish they had taken steps earlier in life to understand their risk and, ideally, have reduced it.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol 52

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page 914-916, March 19, 2024.

Circulation 49

Circulation 49

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Tuberculosis (TB) and human immunodeficiency virus/acquired immunodeficiency syndrome have reached epidemic proportions, particularly affecting vulnerable populations in low- and middle-income countries of sub-Saharan Africa. TB pericarditis is the commonest cardiac manifestation of TB and is the leading cause of constrictive pericarditis, a reversible (by surgical pericardiectomy) cause of diastolic heart failure in endemic areas.

Pericarditis 49

Pericarditis Heart Failure Research Outcomes 49

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page e962-e963, March 19, 2024.

Myocardial Infarction 49

Myocardial Infarction Article Circulation 49

Journal of Cardiothoracic Surgery

MARCH 17, 2024

Celecoxib, a cyclooxygenase-2 selective inhibitor non-steroidal anti-inflammatory drugs, is used for the management of short- and long-term pain as well as in other inflammatory conditions. Unfortunately, its.

Research 45

Research 45

Circulation

MARCH 17, 2024

Circulation, Volume 149, Issue 12 , Page e996-e996, March 19, 2024.

Pharmacology 45

Pharmacology Arrhythmia Circulation 45

HeartRhythm

MARCH 17, 2024

The healing response to cardiac implantable electronic device (CIED) implantation results in inflammation that can result in fibrous pocket formation which may disrupt pocket healing or complicate future interventions.

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Stroke: Vascular and Interventional Neurology

MARCH 17, 2024

Stroke: Vascular and Interventional Neurology, Ahead of Print.

Stroke 40

Stroke Strokes Circulation 40

HeartRhythm

MARCH 17, 2024

When Karl Popper was asked how he would apply his falsifiability standard to the gravitational law espoused by Isaac Newton, he gave the example of an apple moving from the ground up to a branch, and then dancing from one branch to another.1 His answer, obviously provided with tongue in cheek, reminds us that, in science, philosophical postulates are best applied with restraint.

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HeartRhythm

MARCH 17, 2024

Conduction system pacing, in particular left bundle branch pacing, has taken the cardiac pacing world by storm and changed the paradigm of physiological pacing[1, 2].

Physiology 40

Physiology 40

HeartRhythm

MARCH 17, 2024

Implantable loop recorders (ILR) are increasingly used to evaluate patients with unexplained syncope. Identification of all predictors of bradycardic syncope and consequent permanent pacemaker (PPM) insertion is of substantial clinical interest, as patients in the highest-risk category may benefit from upfront pacemaker insertion.

Pacemaker 40

Pacemaker 40