Tue.Feb 06, 2024

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11 leading stroke scientists to receive American Stroke Association honors

American Heart News - Stroke News

Embargoed until 8 a.m. MT/10 a.m. ET, Tuesday, Feb. 6, 2024 PHOENIX, Feb. 6, 2024 – Eleven scientists leading the way in stroke research will be recognized during the American Stroke Association’s International Stroke Conference 2024 for their.

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Heavy Cannabis Use Linked to Increased Risk for Anxiety

HCPLive

A study found 27.5% of individuals who had an emergency department for cannabis use were diagnosed with a new anxiety disorder within 3 years. However, only 5.6% of the general population developed a new anxiety disorder.

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Machine Learning Informs a New Tool to Guide Treatment for Acute Decompensated Heart Failure

DAIC

The Texas Heart Institute at Baylor St. Luke's Medical Center Cardiovascular Disease Fellow Dr. Matthew Segar co-authored a study in JACC Heart Failure led by his research and residency mentor, University of Texas Southwestern Medical Center's Dr. Ambarish Pandey , that utilized a machine learning-based-approach to identify, understand, and predict diuretic responsiveness in patients with acute decompensated heart failure (ADHF).

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A teenager involved in a motor vehicle collision with abnormal ECG

Dr. Smith's ECG Blog

Written by Pendell Meyers A teenager was involved in a motor vehicle collision and presented to the Emergency Department via EMS altered and potentially critically ill. He was intubated for altered mental status. Chest trauma was suspected on initial exam. Here is his initial ECG around 1330: What do you think? The ECG shows sinus tachycardia with RBBB and LAFB, without clear additional superimposed signs of ischemia.

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Triptans Warrant Their Current Contraindication, Analysis Suggests

Med Page Today

(MedPage Today) -- An initial triptan prescription was linked with ischemic stroke and myocardial infarction for people with a high-risk cardiovascular profile, a case-crossover study in Denmark found. Among more than 400,000 people who redeemed.

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Home-Based Albuminuria Screening Cost-Effective for Preventing Kidney, Cardiovascular Events

HCPLive

Findings highlight the potential benefits of implementing home-based screening for albuminuria in the general population to reduce the burden of kidney and cardiovascular diseases while maintaining cost-effectiveness.

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BridgeBio Pharma Announces U.S. Food and Drug Administration (FDA) Acceptance of New Drug Application (NDA) for Acoramidis for the Treatment of Patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

DAIC

Getty Images milla1cf Tue, 02/06/2024 - 20:41 February 6, 2024 — BridgeBio Pharma, Inc., a commercial-stage biopharmaceutical company focused on genetic diseases and cancers, today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing the Company’s New Drug Application (NDA) for acoramidis , an investigational drug for the treatment of ATTR-CM.

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Cortex Announces RESOLVE-AF Trial Evaluating Electrographic Flow (EGF) Mapping for use in Atrial Fibrillation Ablation

DAIC

Getty Images milla1cf Tue, 02/06/2024 - 20:36 February 6, 2024 — Cortex announced the initiation of its RESOLVE-AF trial ( NCT05883631 ), a study formally launched in late October 2023. The international, multi-center trial will provide clinical evaluation of Cortex's 510(k) cleared Ablamap System with electrographic flow (EGF) and newly released Ablacath Mapping Catheter basket mapping catheter to identify extra-pulmonary vein EGF sources.

Ablation 104
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Iron deficiency and supplementation in heart failure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 February 2024; doi:10.1038/s41569-024-00988-1 In this Review, Lakhal-Littleton and Cleland use the latest understanding of iron homeostasis to evaluate existing and emerging markers of iron status, describe the reciprocal relationship between iron status and heart failure, and mechanistically examine the benefits of oral and intravenous iron replacement therapies.

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Major Trends Identified in Emergency Department Discharges Linked to Acute Pulmonary Embolism

HCPLive

These data indicate that in the US, the outpatient management of patients with pulmonary embolism identified as lower-risk may continue to be underutilized.

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Distinguishing heart failure subtypes: the diagnostic power of different cardiac magnetic resonance imaging parameters

Frontiers in Cardiovascular Medicine

Objectives The aim of this retrospective study was to explore the diagnostic potential of various cardiac parameters in differentiating between heart failure with preserved ejection fraction (HFpEF) and heart failure with mid-ranged and reduced ejection fraction (HFm + rEF), and to discern their relationship with normal cardiac function. Methods This research encompassed a comparative analysis of heart failure subtypes based on multiple indicators.

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Cardiology Month in Review: January 2024

HCPLive

This recap of top cardiology news from January 2024 spotlights pipeline updates, new guidance on peripheral interventions, and a celebration of what may be the single most impactful public health address in the history of the United States.

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Veno-arterial extracorporeal membrane oxygenation for respiratory and cardiac support in neonates: a single center experience

Frontiers in Cardiovascular Medicine

Objective Extracorporeal membrane oxygenation (ECMO) is an advanced life support that has been utilized in the neonate for refractory respiratory and circulatory failure. Striving for the best outcomes and understanding optimal surgical techniques continue to be at the forefront of discussion and research. This study presents a single-center experience of cervically cannulated neonatal patients on V-A ECMO, a description of our cannulation/decannulation techniques and our patient outcomes.

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Pan-Genotypic DAA Regimens Safe, Effective for Children, Adolescents with Chronic HCV

HCPLive

Results of the systematic review and meta-analysis support the use of pan-genotypic DAA regimens for the treatment of chronic HCV in adolescents and children ≥ 3 years of age.

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Left ventricular ejection fraction: clinical, pathophysiological, and technical limitations

Frontiers in Cardiovascular Medicine

Risk stratification of cardiovascular death and treatment strategies in patients with heart failure (HF), the optimal timing for valve replacement, and the selection of patients for implantable cardioverter defibrillators are based on an echocardiographic calculation of left ventricular ejection fraction (LVEF) in most guidelines. As a marker of systolic function, LVEF has important limitations being affected by loading conditions and cavity geometry, as well as image quality, thus impacting int

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Evolocumab in Patients With or Without Multivessel Disease

American College of Cardiology

Do patients on evolocumab with multivessel disease (MVD) have more benefit, and will a longer follow-up have a more clinically meaningful benefit in patients without MVD?

Article 69
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Testosterone Ineffective in Preventing Diabetes in Men with Hypogonadism

HCPLive

Testosterone replacement therapy did not differ significantly from placebo in preventing diabetes progression in a substudy of the TRAVERSE randomized trial.

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DYRK1A gene linked to heart defects in Down syndrome

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 February 2024; doi:10.1038/s41569-024-00995-2 A study shows that congenital heart defects in Down syndrome are in part caused by increased dosage of the DYRK1A gene, which lies on chromosome 21, leading to reduced proliferation and mitochondrial dysfunction in cardiomyocytes.

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Adalimumab Biosimilar May Reduce Antibody Response After COVID-19 Vaccine

HCPLive

SARS-CoV-2 antibody levels did not change significantly in patients receiving originator adalimumab, while patients receiving the biosimilar experienced a significant decrease.

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Bariatric Surgery & BP Control; PFA Vasospasm Aftermath; Texas Cardiologist Arrested

Med Page Today

(MedPage Today) -- Even with controlled blood pressure (BP), visit-to-visit systolic BP variability predicts cardiovascular events and may be traced partly to choice of medication. (European Heart Journal) Bariatric surgery proved more effective.

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Nueva certificaciĂłn de rehabilitaciĂłn de ataques o derrames cerebrales para ayudar a mejorar la atenciĂłn en instalaciones de enfermerĂ­a especializada

American Heart News - Stroke News

DALLAS, 6 de febrero de 2024 — El derrame cerebral es una de las principales causas de discapacidad grave a largo plazo en los EE. UU. y aproximadamente 795,000 personas cada año experimentan un derrame cerebral nuevo o recurrente, según la actualización.

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Socioeconomic status as a predictor of post-operative mortality and outcomes in carotid artery stenting vs. carotid endarterectomy

Frontiers in Cardiovascular Medicine

Background The association between low socioeconomic status (SES) and worse surgical outcomes has become an emerging area of interest. Literature has demonstrated that carotid artery stenting (CAS) poses greater risk of postoperative complications, particularly stroke, than carotid endarterectomy (CEA). This study aims to compare the impact of low SES on patients undergoing CAS vs.

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A successful endovascular aortic repair of aortoesophageal fistula following esophagectomy: a case report and literature review

Journal of Cardiothoracic Surgery

Aortoesophageal fistula (AEF) is an extremely rare and highly fatal complication leading to a high risk of morbidity and mortality. Successful management of AEF after esophagectomy for esophageal carcinoma has.

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STEMI – Anterior Wall

All About Cardiovascular System and Disorders

STEMI – Anterior Wall ECG shows ST elevation myocardial infarction of anterior wall. Up sloping elevation of ST segment is seen in leads V1 to V5, with maximum ST elevation in V2, as is characteristic of anterior wall infarction. T waves are inverted in leads V2 to V5 suggesting that it is an evolved myocardial infarction rather than in the very early phase.

STEMI 52
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Coral reef aorta: a rare form of obstruction of the ascending aorta in adolescent with aortopathy- case report

Journal of Cardiothoracic Surgery

Supra aortic obstruction in children is uncommon and is seen in certain unique conditions. While intraluminal obstruction due to heavy calcification is seen in older populations, it is not described in pediatr.

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Cassling Celebrates 20 Years of Complimentary Continuing Education Program for Imaging Professionals

Cassling

In 2023, Cassling provided nearly 5,000 free Continuing Education credits to imaging professionals around the country. Omaha, Neb. (February 6, 2024) – Cassling, a family-owned company providing hospital providers of all sizes with imaging and therapeutic technology, services and solutions, is excited to announce the 20 th anniversary of its nationwide Continuing Education program, Investing In You.

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Jace Reminds Us of Hope and Joy

Conquering CHD

Jace, born in October 2021, arrived with a hefty challenge – Tetralogy of Fallot with Pulmonary Atresia and Double Outlet Right Ventricle, a mouthful for such a tiny fighter. At just 10 days old, he embarked on his first adventure: a complex heart repair at Columbia University Medical Center. Though the operation was a success, the journey home held its own hurdles.

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E-Cigarette Trends: Spotlighting Prevalence, Demographic Trends Among Smokers

HCPLive

This analysis of trends in e-cigarette prevalence highlights several important trends among smokers, updating the current literature with new information about demographics and other data.

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Review on Cardiac Implantable Electronic Devices: Key Points

American College of Cardiology

The following are key points to remember from a review article on cardiac implantable electronic devices (CIEDs), which include pacemakers for bradycardia, biventricular pacemakers for heart failure, and implantable cardioverter–defibrillators (ICDs) for the treatment of sudden cardiac death:

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Lurasidone Linked to Improving Social Functioning for Schizophrenia

HCPLive

A new study found patients with schizophrenia on lurasidone had an effect size change of 0.33 on the PANSS prosocial subscale, suggesting improvements in social functioning.

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ACCEL Lite: Management of Worsening Heart Failure with Reduced Ejection Fraction

American College of Cardiology

In this interview, Javed Butler, MD, MPH, MBA, FACC, and Matthew Martinez, MD, FACC, discuss Management of Worsening Heart Failure with Reduced Ejection Fraction.

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A pilot clinical assessment of biphasic asymmetric pulsed field ablation catheter for pulmonary vein isolation

Frontiers in Cardiovascular Medicine

Pulsed field ablation (PFA) is a new treatment for atrial fibrillation (AF), and its selective ablation characteristics give it a significant advantage in treatment. In previous cellular and animal experiments, we have demonstrated that biphasic asymmetric pulses can be used to ablate myocardial tissue. However, small-scale clinical trials are needed to test whether this approach is safe and feasible before extensive clinical trials can be performed.

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Top 5 Must-Know Features of Getting Effective Healthcare Training

ADN Center of Excellence

As a dedicated physician, your commitment to lifelong learning is paramount. In the fast-paced world of healthcare, staying abreast of the latest advancements and best practices is not just beneficial it's essential for delivering optimal patient care. That's why we're here to equip you with the top five must-know features for taking your healthcare training to the next level.

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Elevated remnant cholesterol and non-HDL cholesterol concentrations from real-world laboratory results: a cross-sectional study in Southeast Asians

Frontiers in Cardiovascular Medicine

Introduction Triglyceride-rich remnant lipoproteins (TRLs) are considered atherogenic due to the presence of remnant cholesterol, which is transported by apolipoprotein B. In clinical practice, the concentration of TRLs can be estimated by calculating remnant cholesterol or non-HDL cholesterol levels. Aim This study aims to investigate the proportion of patients who have low LDL cholesterol (LDL-C) concentration but elevated remnant cholesterol concentration, stratified by the presence of hypert

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Unilateral Primary Aldosteronism: Long-Term Disease Recurrence After Adrenalectomy

Hypertension Journal

Hypertension, Ahead of Print. BACKGROUND:Primary aldosteronism (PA) is frequently caused by a unilateral aldosterone-producing adenoma with a PA-driver mutation. Unilateral adrenalectomy has a high probability of short-term biochemical remission, but long-term postsurgical outcomes are relatively undefined. Our objective was to investigate the incidence of long-term recurrence of PA in individuals with postsurgical short-term biochemical remission.METHODS:Adrenalectomized patients for unilateral

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Association Between Cardiovascular Event Type and Smoking Cessation Rates Among Outpatients With Atherosclerotic Cardiovascular Disease: Insights From the NCDR PINNACLE Registry

Circulation: Cardiovascular Quality & Outcomes

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Background:It is unclear how the type of an atherosclerotic cardiovascular disease (ASCVD) event potentially influences patients’ likelihood of smoking cessation.Methods:Using 2013 to 2018 data from the US based National Cardiovascular Data Registry Practice Innovation and Clinical Excellence outpatient cardiac registry, we identified patients who were current smokers at a clinic visit and followed them over time for a subsequent

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Transbronchial lymph node forceps biopsy as a novel tool in diagnosis of mediastinal lymphadenopathy: a pilot study

Journal of Cardiothoracic Surgery

Differential diagnosis of mediastinal lymphadenopathy is an issue of debate. Lymph nodes may be enlarged due to a variety of inflammatory, infectious, or malignant reasons. Therefore, obtaining samples from th.