Sun.Sep 22, 2024

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Edgewise Therapeutics’ EDG-7500 Emerges as New HCM Contender

CardiacWire

A new HCM competitor emerged last week, after Edgewise Therapeutics’ EDG-7500 showed strong evidence of its safety and efficacy in a pair of early-stage trials. EDG-7500 is an oral cardiac sarcomere modulator designed to slow early contraction velocity and address impaired cardiac relaxation associated with HCM and other diastolic dysfunctions. EDG-7500 is later to the HCM party than BMS’ Camzyos and Cytokinetics’ aficamten, but is differentiated by its potential to improve blood flow without sa

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Weather Only Has Small Impact on Psoriatic Arthritis Symptoms

HCPLive

Gender, age, and disease duration significantly affected symptom variations.

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Toxic epidermal necrolysis following heart transplantation may caused by cefoperazone sodium and sulbactam sodium

Journal of Cardiothoracic Surgery

The outcome of heart transplantation is significantly affected by perioperative infections. Individualised immunosuppression strategies are essential to reduce the risk of such infections.

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Cryo-X-ray phase contrast imaging for 3D structural and molecular analysis of frozen biopsy samples

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 September 2024; doi:10.1038/s41569-024-01084-0 In this Tools of the Trade article, Li and Bonnin describe the use of cryo-X-ray phase contrast imaging to assess frozen myocardial biopsy samples.

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Pulmonary embolism and intracardiac foreign bodies caused by bone cement leakage: a case report and literature review

Journal of Cardiothoracic Surgery

Percutaneous vertebroplasty (PVP) is a surgical procedure that involves injecting polymethylmethacrylate (PMMA) bone cement into the diseased vertebrae to rapidly relieve pain and strengthen the vertebrae. We.

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Disparities and Trends in Autopsy Rates Among Cardiovascular Disease Decedents in the US, 2011-2020

The American Journal of Cardiology

Publication date: Available online 21 September 2024 Source: The American Journal of Cardiology Author(s): Marco Zuin, Gianluca Rigatelli, Claudio Bilato, C Micheal Gibson, Thach Nguyen

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Thrombotic Thrombocytopenia Purpura (TTP) following emergent aortic valve replacement after a complicated TAVR procedure: a case report and review of the literature

Journal of Cardiothoracic Surgery

Thrombotic thrombocytopenic purpura (TTP) is a rare hematological disorder. The occurrence of TTP subsequent to an emergent aortic valve replacement after a TAVR procedure is exceedingly uncommon with only a f.

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Voltage mapping and right ventriculography to guide ablation for arrhythmogenic right ventricular cardiomyopathy ventricular tachycardia: a case report

Journal of Cardiothoracic Surgery

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a family inherited cardiomyopathy associated with ventricular arrhythmias. With the development of molecular biology, histology, imaging, and other dia.

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Advanced Liver Fibrosis Negatively Impacts Quality of Life in T2D

HCPLive

Obesity and advanced fibrosis were independent predictors of impaired health-related quality of life in people with T2D.

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Correlation analysis between the expression of serum microRNA-665 and the degree of coronary artery stenosis and major adverse cardiovascular events in patients with acute myocardial infarction

Journal of Cardiothoracic Surgery

The purpose of this study was to explore the expression of miR-665 in acute myocardial infarction (AMI) and evaluate its significance in the diagnosis and prognosis of AMI.

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Outcomes of Acute Myocardial Infarction in Patients with Systemic Lupus Erythematosus: A Propensity-Matched Nationwide Analysis

The American Journal of Cardiology

Publication date: Available online 21 September 2024 Source: The American Journal of Cardiology Author(s): Ali Bin Abdul Jabbar, Mahmoud Ismayl, Anjali Mishra, Ryan W. Walters, Andrew M. Goldsweig, Herbert D Aronow, Abubakar Tauseef, Ahmed S.

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From the Literature

Circulation

Circulation, Volume 150, Issue 13 , Page 1059-1060, September 24, 2024.

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Letter by Zhang Regarding Article, “Coronary Angiography, Intravascular Ultrasound, and Optical Coherence Tomography for Guiding of Percutaneous Coronary Intervention: A Systematic Review and Network Meta-Analysis”

Circulation

Circulation, Volume 150, Issue 13 , Page e269-e270, September 24, 2024.

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ECG Changes in a Patient With Recurrent Palpitations

Circulation

Circulation, Volume 150, Issue 13 , Page 1061-1063, September 24, 2024.

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Heterogeneity of Treatment Effects in Clinical Trials: Overview of Multivariable Approaches and Practical Recommendations

Circulation

Circulation, Volume 150, Issue 13 , Page 978-980, September 24, 2024.

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Kidney Disease as a Cardiovascular Disease Priority

Circulation

Circulation, Volume 150, Issue 13 , Page 975-977, September 24, 2024.