All About Cardiovascular System and Disorders

DECEMBER 15, 2024

Bernoulli equation for calculation of pressure gradient by Doppler echocardiography is: A: P=2V 2 B: P=3V 2 C: P=4V 2 D: P=4V 3 Correct answer: C: P=4V 2 Original Bernoulli equation is a complex equation. This is a simplified equation routinely used in Doppler echocardiography for pressure gradient across valves while quantifying severity of stenosis.

Stenosis 52

Stenosis General Cardiology 52

Med Page Today

DECEMBER 15, 2024

(MedPage Today) -- ProPublica is a Pulitzer Prize-winning investigative newsroom. Sign up for The Big Story newsletter to receive stories like this one in your inbox. The drug potassium chloride has been on the market for decades, widely prescribed.

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HCPLive

DECEMBER 15, 2024

Machine learning models improve accuracy in detecting MASH with F2-F3 fibrosis, surpassing noninvasive tests in sensitivity, specificity, and predictive value.

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Medical Xpress - Cardiology

DECEMBER 15, 2024

It's the time of year for workplace Christmas parties, and gatherings with family and friends. Maybe you'll drink a lot in one go.

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Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

HCPLive

DECEMBER 15, 2024

Matthew J. Budoff, MD describes bridging the gap between atherosclerosis and osteoporosis through advanced Imaging techniques.

Atherosclerosis 98

Atherosclerosis 98

Heart Sisters

DECEMBER 15, 2024

"Your tests all look fine!" (No one quite knows the reason). You're probably just feeling stressed by the season!

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Heart Attack Heart attacks Heart Disease 81

Nature Reviews - Cardiology

DECEMBER 15, 2024

Nature Reviews Cardiology, Published online: 16 December 2024; doi:10.1038/s41569-024-01112-z Macrophagefibroblast interactions have a central role in cardiac fibrosis. In response to left ventricular pressure overload, CCR2+ cardiac macrophages acquire a fibrogenic phenotype, secreting IL-1 and promoting the activation of a FAP+ POSTN+ fibroblast subpopulation through the transcription factor MEOX1.

Heart Failure 54

Heart Failure 54

HCPLive

DECEMBER 15, 2024

Real-world data from 18,710 MASH patients highlight the impact of comorbidities, biomarkers, and region on mortality, with 70% of deaths CVD-related.

Biomarkers 52

Biomarkers 52

HeartRhythm

DECEMBER 15, 2024

There is a large variability in the management of conduction disturbances (CDs) after transcatheter aortic valve replacement (TAVR).

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Aortic valve Aortic TAVR 40

European Journal of Heart Failure

DECEMBER 15, 2024

Abstract Aims Patients with a reduced left ventricular ejection fraction (LVEF) following an acute myocardial infarction (MI) are considered to be at risk of progressive adverse cardiac remodelling which can lead to the development of heart failure and death. The early addition of a sodiumglucose cotransporter 2 (SGLT2) inhibitor to standard treatment may delay or prevent progressive adverse remodelling in these patients.

Myocardial Infarction 40

Myocardial Infarction Heart Failure Outcomes Research 40

HeartRhythm

DECEMBER 15, 2024

Left atrial posterior wall isolation (LAPWI) plus pulmonary vein isolation (PVI) can be performed with radiofrequency ablation, cryoballoon ablation (CB-A), or, recently, pulsed field ablation (PFA).

Pulmonary 40

Pulmonary Atrial Fibrillation Ablation Outcomes 40

European Journal of Heart Failure

DECEMBER 15, 2024

A summary of effect of sacubitril/valsartan in heart failure with preserved ejection fraction across the age spectrum. All participants in PARAGON-HF were divided into three age groups: <65years, 6574years, and75years. Compared to younger participants, older participants had worse clinical outcomes ( A ), derived similar benefits from sacubitril/valsartan ( B ), despite being more likely to develop hypotension when randomized to sacubitril/valsartan ( C ).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Laboratory Echocardiogram 40

HeartRhythm

DECEMBER 15, 2024

A novel focal lattice-tip catheter allowing the delivery of either pulsed field (PF) or radiofrequency (RF) energy has recently received regulatory approval. The technology features a proprietary 3-dimensional electroanatomic mapping system.

Arrhythmia 40

Arrhythmia Technology Ablation 40

Circulation

DECEMBER 15, 2024

Circulation, Volume 150, Issue 25 , Page e712-e763, December 17, 2024.

Circulation 40

Circulation 40

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

BackgroundHypertensive disorders of pregnancy (HDP) predispose a woman to maternity-related cardiovascular morbidity and mortality. However, there is limited literature on HDP among women of African descent in Canada.Methods and designA convergent mixed-method study will be used to investigate the intersection of self-reported HDP risks in women of African descent in Canada with a history of a HDP (quantitative, cross-sectional survey) and explore the perception and experiences of women of Afric

Hypertension 40

Hypertension Risk Factors Cardiovascular Disease 40

European Journal of Heart Failure

DECEMBER 15, 2024

Abstract Aims The aim of this study was to describe the prognostic importance of left ventricular ejection fraction (LVEF) versus right ventricular (RV) dilatation and dysfunction in patients with heart failure (HF) from countries of different income levels. Methods and results We enrolled 17321 participants with HF from 40 countries. Participants were followed for a median (25th75th percentile) of 2.1 (2.04.6)years.

Heart Failure 40

Heart Failure Blood Pressure Atrial Fibrillation Cardiomyopathy 40

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

BackgroundArrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized by high risks of sustained ventricular tachycardia (sVT) and sudden cardiac death. Identifying patients with high risk of sVT is crucial for the management of ACM.MethodsA total of 147 ACM patients were retrospectively enrolled in the observational study and divided into training and validation groups.

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Cardiomyopathy Tachycardia Sudden Cardiac Death Heart Failure 52

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

Coronary artery disease (CAD)cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteriesis responsible for disabilities of millions of people worldwide and remains the most common single cause of death. Inflammation is the primary pathological mechanism underlying CAD, since is involved in atherosclerotic plaque formation.

Coronary Artery Disease 98

Coronary Artery Disease Atherosclerosis Plaque 98

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

BackgroundA 63-year-old Black woman presented with progressive exertional dyspnea and chronic lower back pain. The course and findings in her case are instructive.Case reportFamily history was notable for cardiac deaths. An echocardiogram demonstrated ventricular wall thickening with diastolic dysfunction. The patients N-terminal pro b-type natriuretic peptide level was 1,691pg/ml with a troponin I level of 0.36ng/ml.

Stenosis 52

Stenosis Heart Failure Echocardiogram 52

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

BackgroundCoronary Artery Disease (CAD) is a leading cause of mortality, with an increasing number of patients affected by coronary artery stenosis each year. Coronary angiography (CAG) is commonly employed as the definitive diagnostic tool for identifying coronary artery stenosis. Physician Visual Assessment (PVA) is often used as the primary method to determine the need for further intervention, but its subjective nature poses challenges.

Stenosis 52

Stenosis Coronary Artery Disease Ischemia Research 52

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

Osimertinib is first-line treatment for epidermal growth factor (EGFR)-mutated non-small cell lung cancer (NSCLC) and has been associated with cardiotoxicity. However, the nature of cardiac remodeling and associated risk factors remains incompletely understood. Retrospective analysis of NSCLC patients with 1 echocardiogram post-osimertinib between 2007 and 2022 was performed.

Cancer 52

Cancer Electrocardiogram BMI Risk Factors 52

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

IntroductionPreeclampsia (PE) is thought to be the consequence of impaired placental perfusion leading to placental hypoxia. While it has been demonstrated that PE may be a consequence of maternal cardiovascular maladaptation, the exact role of maternal cardiac function remains to be determined. This study sought to assess cardiac characteristics in pregnant women diagnosed with PE and to determine the possible relationship between PE, maternal cardiac changes/function, and NT-proBNP levels.Meth

Cardiac Function 52

Cardiac Function Tricuspid Pulmonary Hypertension 52

Frontiers in Cardiovascular Medicine

DECEMBER 15, 2024

IntroductionLow atrial voltage and slow conduction velocity (CV) have been associated with atrial fibrillation (AF); however, their interaction and relative importance as early disease markers remain incompletely understood. We aimed to elucidate the relationship between atrial voltage and CV using high-density electroanatomic (HDE) maps of patients with AF.MethodsHDE maps obtained during sinus rhythm in 52 patients with AF and five healthy controls were analysed.

Atrial Fibrillation 52

Atrial Fibrillation Ablation Arrhythmia Research 52