Sun.Dec 15, 2024

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Anti-inflammatory effects of glucagon-like peptide-1 (GLP-1) in coronary artery disease: a comprehensive review

Frontiers in Cardiovascular Medicine

Coronary artery disease (CAD)cardiovascular condition occuring due to atherosclerotic plaque accumulation in the epicardial arteriesis responsible for disabilities of millions of people worldwide and remains the most common single cause of death. Inflammation is the primary pathological mechanism underlying CAD, since is involved in atherosclerotic plaque formation.

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Machine-Learning Models Could Help ID MASH Patients Considered Candidates for Resmetirom

HCPLive

Machine learning models improve accuracy in detecting MASH with F2-F3 fibrosis, surpassing noninvasive tests in sensitivity, specificity, and predictive value.

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The Grinch’s Guide to Women’s Heart Attacks (with apologies to Dr. Seuss)

Heart Sisters

"Your tests all look fine!" (No one quite knows the reason). You're probably just feeling stressed by the season!

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Study Highlights Real-World Morality Rates, Factors Increasing Mortality Risk in MASH

HCPLive

Real-world data from 18,710 MASH patients highlight the impact of comorbidities, biomarkers, and region on mortality, with 70% of deaths CVD-related.

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Bernoulli equation for Doppler pressure gradient

All About Cardiovascular System and Disorders

Bernoulli equation for calculation of pressure gradient by Doppler echocardiography is: A: P=2V 2 B: P=3V 2 C: P=4V 2 D: P=4V 3 Correct answer: C: P=4V 2 Original Bernoulli equation is a complex equation. This is a simplified equation routinely used in Doppler echocardiography for pressure gradient across valves while quantifying severity of stenosis.

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Matthew J. Budoff, MD: Examining the Interplay of Coronary Calcium and Osteoporosis

HCPLive

Matthew J. Budoff, MD describes bridging the gap between atherosclerosis and osteoporosis through advanced Imaging techniques.

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Differences in severity of diffuse and focal coronary stenosis between visual and quantitative assessment

Frontiers in Cardiovascular Medicine

BackgroundCoronary Artery Disease (CAD) is a leading cause of mortality, with an increasing number of patients affected by coronary artery stenosis each year. Coronary angiography (CAG) is commonly employed as the definitive diagnostic tool for identifying coronary artery stenosis. Physician Visual Assessment (PVA) is often used as the primary method to determine the need for further intervention, but its subjective nature poses challenges.

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The impact of atrial voltage and conduction velocity phenotypes on atrial fibrillation recurrence

Frontiers in Cardiovascular Medicine

IntroductionLow atrial voltage and slow conduction velocity (CV) have been associated with atrial fibrillation (AF); however, their interaction and relative importance as early disease markers remain incompletely understood. We aimed to elucidate the relationship between atrial voltage and CV using high-density electroanatomic (HDE) maps of patients with AF.MethodsHDE maps obtained during sinus rhythm in 52 patients with AF and five healthy controls were analysed.

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Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association’s Scientific Sessions 2024 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2024

Circulation

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Case Report: Avoiding misdiagnosis in amyloidosis—navigating transthyretin genopositivity and monoclonal gammopathy in a patient with advanced heart failure and spinal stenosis

Frontiers in Cardiovascular Medicine

BackgroundA 63-year-old Black woman presented with progressive exertional dyspnea and chronic lower back pain. The course and findings in her case are instructive.Case reportFamily history was notable for cardiac deaths. An echocardiogram demonstrated ventricular wall thickening with diastolic dysfunction. The patients N-terminal pro b-type natriuretic peptide level was 1,691pg/ml with a troponin I level of 0.36ng/ml.

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Future of Antihypertensive Therapies

Circulation

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Cardiac function in pregnant women with preeclampsia

Frontiers in Cardiovascular Medicine

IntroductionPreeclampsia (PE) is thought to be the consequence of impaired placental perfusion leading to placental hypoxia. While it has been demonstrated that PE may be a consequence of maternal cardiovascular maladaptation, the exact role of maternal cardiac function remains to be determined. This study sought to assess cardiac characteristics in pregnant women diagnosed with PE and to determine the possible relationship between PE, maternal cardiac changes/function, and NT-proBNP levels.Meth

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Addressing Known hypertensive disOrders of pregnancy in woMen of African descent in Canada (AKOMA): protocol for a mixed method study

Frontiers in Cardiovascular Medicine

BackgroundHypertensive disorders of pregnancy (HDP) predispose a woman to maternity-related cardiovascular morbidity and mortality. However, there is limited literature on HDP among women of African descent in Canada.Methods and designA convergent mixed-method study will be used to investigate the intersection of self-reported HDP risks in women of African descent in Canada with a history of a HDP (quantitative, cross-sectional survey) and explore the perception and experiences of women of Afric

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A new prediction model for sustained ventricular tachycardia in arrhythmogenic cardiomyopathy

Frontiers in Cardiovascular Medicine

BackgroundArrhythmogenic cardiomyopathy (ACM) is an inherited cardiomyopathy characterized by high risks of sustained ventricular tachycardia (sVT) and sudden cardiac death. Identifying patients with high risk of sVT is crucial for the management of ACM.MethodsA total of 147 ACM patients were retrospectively enrolled in the observational study and divided into training and validation groups.

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Cardiac events and dynamic echocardiographic and electrocardiogram changes following osimertinib treatment in lung cancer

Frontiers in Cardiovascular Medicine

Osimertinib is first-line treatment for epidermal growth factor (EGFR)-mutated non-small cell lung cancer (NSCLC) and has been associated with cardiotoxicity. However, the nature of cardiac remodeling and associated risk factors remains incompletely understood. Retrospective analysis of NSCLC patients with 1 echocardiogram post-osimertinib between 2007 and 2022 was performed.

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