Open Heart

OCTOBER 30, 2023

Objective Animal data suggest that exercise during chemotherapy is cardioprotective, but clinical evidence to support this is limited. This study evaluated the effect of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity. Methods This is a follow-up study of two previously performed randomised trials in patients with breast cancer allocated to exercise during chemotherapy or non-exercise controls.

Exercise 52

Exercise Cancer Research 52

NOVARAD

OCTOBER 30, 2023

In our fast-paced digital age, instant access to information is not a luxury but a necessity. For years, the medical imaging sector clung to outdated practices, such as distributing crucial images via CDs —a time-consuming method often fraught with challenges.

Technology 52

Technology 52

Coronary Artery Disease Journal

OCTOBER 30, 2023

Introduction Elevated peak cardiac troponin levels have been linked with increased morbidity and mortality in patients with acute myocardial infarction (AMI). Immature Platelets are young and relatively large platelets that are hyper-reactive and pro-thrombotic compared to regular platelets. Increased immature platelet fraction (IPF) has been associated with an elevated risk of thrombotic events.

Myocardial Infarction 52

Myocardial Infarction STEMI 52

American Heart News - Stroke News

OCTOBER 30, 2023

Research Highlights: Cardiovascular deaths from extreme heat in the United States are projected to increase by 162% by the middle of the century, based on a hypothetical scenario where currently proposed U.S. policies to reduce greenhouse gas.

Research 52

Research 52

Coronary Artery Disease Journal

OCTOBER 30, 2023

Introduction Several blood inflammatory markers, such as high-sensitivity C-reactive protein (hs-CRP), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), are linked to increased risk for cardiovascular diseases. This study aimed to evaluate these inflammatory markers after cardiac rehabilitation (CR) in patients with unstable ischemic heart disease (UIHD) who underwent successful percutaneous coronary intervention (PCI).

Cardiac Rehabilitation 52

Cardiac Rehabilitation Heart Disease Biomarkers Cardiovascular Disease 52

Conquering CHD

OCTOBER 30, 2023

Medical imaging plays an essential role in CHD care. However, for parents, the thought of their child undergoing medical imaging can be a source of stress and anxiety. It’s not uncommon for children to feel scared or uneasy about the process, making it difficult for them to sit still and cooperate with the medical team. Tips and Tricks for Kids and Medical Imaging Here are some strategies you can use to help your child cope and sit still during medical imaging from other CHD parents. 1.

Outcomes 52

Outcomes Education Blog 52

Journal of Cardiovascular Pharmacology

OCTOBER 30, 2023

ABSTRACT: Central sleep apnea (CSA) is common in patients with heart failure. Recent studies link ticagrelor use with CSA. We aimed to evaluate CSA prevalence in patients with coronary heart disease (CHD) and whether ticagrelor use is associated with CSA. We reviewed consecutive patients with CHD who underwent a polysomnography (PSG) test over a 5-year period from three sleep centers.

Heart Disease 40

Heart Disease Atrial Fibrillation Heart Failure Article 40

Journal of Cardiovascular Pharmacology

OCTOBER 30, 2023

Abstract: Pulmonary artery hypertension (PAH) is characterized by pulmonary arterial endothelial cells (PAECs) dysfunction and pulmonary artery smooth muscle cells (PASMCs) activation. For decades, the therapies for PAH based on stem cells have been shown to be effective. Meanwhile, Tumor necrosis factor (TNF)-α-induced protein-8 (TNFAIP8)-like 2 (TIPE2) promote the viability of human amniotic mesenchymal stem cells.

Pulmonary 40

Pulmonary Hypertension Article 40

Stroke Journal

OCTOBER 30, 2023

Stroke, Volume 54, Issue 12 , Page 3038-3045, December 1, 2023. BACKGROUND:Daily exposure to ambient air pollution is associated with stroke morbidity and mortality; however, the association between hourly exposure to air pollutants and risk of emergency hospital admissions for stroke and its subtypes remains relatively unexplored.METHODS:We obtained hourly concentrations of fine particulate matter (PM2.5), respirable particulate matter (PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone

Hospital 40

Hospital Stroke Strokes Public Health 40

Journal of Cardiovascular Pharmacology

OCTOBER 30, 2023

ABSTRACT: Mounting evidence suggests that CYP epoxygenase-derived metabolites of docosahexaenoic acid, called epoxydocosapentaenoic acids (EDPs), limit mitochondrial damage following cardiac injury. In particular, the 19,20-EDP regioisomer has demonstrated potent cardioprotective action. Thus, we investigated our novel synthetic 19,20-EDP analog SA-22 for protection against cardiac IR injury.

Ischemia 40

Ischemia Outcomes Article 40

Hypertension Journal

OCTOBER 30, 2023

Hypertension, Ahead of Print. Background:Preeclampsia, a pregnancy-specific condition associated with new-onset hypertension after 20-week gestation, is a leading cause of maternal and neonatal morbidity and mortality. Predictive tools to understand which individuals are most at risk are needed.Methods:We identified a cohort of N=1125 pregnant individuals who delivered between May 2015 and May 2022 at Mass General Brigham Hospitals with available electronic health record data and linked genetic

Blood Pressure 40

Blood Pressure Risk Factors Hypertension Hospital 40

European Journal of Heart Failure

OCTOBER 30, 2023

Results of the CLOROTIC trial according to glomerular filtration rate. AHF, acute heart failure; eGFR, estimated glomerular filtration rate; HCTZ, hydrochlorothiazide. Aims In patients with acute heart failure (AHF), the addition of hydrochlorothiazide (HCTZ) to furosemide improved diuretic response in the CLOROTIC trial. This work aimed to evaluate if these effects differ across the estimated glomerular filtration rate (eGFR) spectrum.

Heart Failure 40

Heart Failure Research Article 40

HeartRhythm

OCTOBER 30, 2023

Observational studies have suggested associations between some atherogenic risk factors and atrioventricular block (AV-block).

Blood Pressure 40

Blood Pressure Risk Factors 40

European Journal of Heart Failure

OCTOBER 30, 2023

Summary of the study design and key findings. CMR, cardiac magnetic resonance; LV, left ventricular; LVEDVi, left ventricular end-diastolic volume index; LVEF, left ventricular ejection fraction; LVESVi, left ventricular end-systolic volume index; MI, myocardial infarction; pPCI, primary percutaneous coronary intervention; SE, standard error; STEMI, ST-elevation myocardial infarction.

Myocardial Infarction 40

Myocardial Infarction STEMI Angioplasty Research 40

Coronary Artery Disease Journal

OCTOBER 30, 2023

An abstract is unavailable.

Stenosis 52

Stenosis Stents Stent 52

European Journal of Heart Failure

OCTOBER 30, 2023

ABSTRACT Aim Expected 1-year survival is essential to risk stratification of patients with heart failure (HF); however, little is known about the 1-year prognosis of patients with HF and cancer. Thus, the objective was to investigate the 1-year prognosis following new-onset HF stratified by cancer status in patients with breast, gastrointestinal, or lung cancer.

Cancer 40

Cancer Heart Failure Research Article 40

Coronary Artery Disease Journal

OCTOBER 30, 2023

An abstract is unavailable.

Ultrasound 52

Ultrasound 52

European Journal of Heart Failure

OCTOBER 30, 2023

Main findings of the mineralocorticoid receptor antagonist (MRA) subgroup analysis of the EMPULSE trial. *The hierarchy and components of the primary outcome measured by the win ratio were: (1) time to all-cause death; (2) number of heart failure events (HFE); (3) time to first HFE; (4) ≥5 point difference in change from baseline in the Kansas City Cardiomyopathy Questionnaire (KCCQ) total symptom score after 90 days of treatment.

Heart Failure 40

Heart Failure Outcomes Cardiomyopathy Hospital 40

Dr. Smith's ECG Blog

OCTOBER 30, 2023

A 60 yo with 2 previous inferior (RCA) STEMIs, stented, called 911 for one hour of chest pain. He had no h/o heart failure. Here is the first prehospital ECG (time 0, after one hour of pain): I do not see evidence of OMI, and neither did the Queen of Hearts Here is the 2nd prehospital ECG (time 10 minutes, after 70 minutes of pain): No change On arrival, the first ED ECG was recorded 20 minutes after the last one (90 minutes after pain onset): What do you think?

STEMI 112

STEMI Heart Failure Stents Stent 112

European Journal of Heart Failure

OCTOBER 30, 2023

Prediction models for risk of incident heart failure in the community demonstrated excellent prediction performance but their usefulness in clinical practice remains uncertain. ARIC, Atherosclerosis Risk in Communities; CI, confidence interval; GRAM, GRaph-based Attention Model; PCP-HF, Pooled Cohort equations to Prevent Heart Failure; RETAIN, REverse Time AttentIoN model.

Heart Failure 40

Heart Failure Atherosclerosis Research Article 40

Coronary Artery Disease Journal

OCTOBER 30, 2023

Background The relationship between myocardial infarct size (MIS) on late gadolinium-enhanced cardiac MRI (LGE MRI) and myocardial work (MW) indices assessed with MW echocardiography (MWE) has not been well characterized. This study aimed to determine an impaired MW using MIS in patients with acute myocardial infarction. Methods Left ventricular (LV) two-dimensional speckle-tracking echocardiography, MWE, and LGE MRI were performed in 33 patients with ST-segment elevation myocardial infarction a

Myocardial Infarction 52

Myocardial Infarction 52

European Journal of Heart Failure

OCTOBER 30, 2023

Assessment of fluid overload identifies aortic stenosis (AS) patients at high risk and treatment of fluid overload may potentially improve the post-interventional clinical course. TAVI, transcatheter aortic valve implantation. Aims Cardiac decompensation in aortic stenosis (AS) involves extra-valvular cardiac damage and progressive fluid overload (FO).

Stenosis 40

Stenosis Aortic Aortic valve Outcomes 40

Hypertension Journal

OCTOBER 30, 2023

Hypertension, Ahead of Print. Background:Aortic stiffness, assessed as carotid-femoral pulse wave velocity, provides a measure of vascular age and risk for adverse cardiovascular disease outcomes, but it is difficult to measure. The shape of arterial pressure waveforms conveys information regarding aortic stiffness; however, the best methods to extract and interpret waveform features remain controversial.Methods:We trained a convolutional neural network with fixed-scale (time and amplitude) brac

Cardiovascular Disease 40

Cardiovascular Disease Cholesterol Heart Failure Blood Pressure 40

European Journal of Heart Failure

OCTOBER 30, 2023

In patients with heart failure with preserved ejection fraction (HFpEF), abnormal global longitudinal strain (GLS) is a strong predictor for clinical events and can help identity patients who are at risk for future decline in left ventricular ejection fraction (LVEF). Aims Patients with heart failure with preserved ejection fraction (HFpEF) are at high risk for hospitalization and mortality and many of these patients experience a deterioration in left ventricular ejection fraction (LVEF) over ti

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Outcomes Hospital 40

European Journal of Heart Failure

OCTOBER 30, 2023

Patient-reported knowledge of self-care in heart failure (HF) with reduced ejection fraction. ( A ) Distribution of answers to the Kansas City Cardiomyopathy Questionnaire ‘prevention’ and ‘response’ questions. ( B ) Outcomes shown as rates per 100 person-years according to category of patient-reported knowledge of self-care. In the right panel, the ‘Poor’ group includes ‘not at all’, ‘not very much’, and ‘somewhat’; ‘Fair’ includes ‘mostly’; ‘Good’ includes ‘completely.

Heart Failure 40

Heart Failure Outcomes Education Cardiomyopathy 40

European Journal of Heart Failure

OCTOBER 30, 2023

Aims There are no accepted quality indicators for transitional care following hospitalization for heart failure (HF). Current quality measures focus on 30-day readmissions without accounting for competing risks such as death. In this scoping review of clinical trials, we aimed to develop a set of HF transitional care quality indicators for clinical or research applications following hospitalization for HF.

Heart Failure 40

Heart Failure Research Outcomes Hospital 40

European Journal of Heart Failure

OCTOBER 30, 2023

Integration of palliative care in the 2021 ESC and the 2022 AHA/ACC/HFSA heart failure guidelines. ACC, American College of Cardiology; AHA, American Heart Association; ESC, European Society of Cardiology; HF, heart failure; HFSA, Heart Failure Society of America; LD, limited; R, randomized. ABSTRACT The role of palliative care for patients with heart failure (HF) is discussed in both most recent HF guidelines, the 2021 ESC guideline and the 2022 AHA/ACC/HFSA guideline.

Heart Failure 40

Heart Failure Article 40

European Journal of Heart Failure

OCTOBER 30, 2023

Illustration of study inclusion and stress test modalities. Haemodynamic curve morphology is displayed for right atrial (RAP), right ventricular (RVP), mean pulmonary artery (PAP), and pulmonary capillary wedge pressure (PAWP). ΔPAWP: difference of PAWP between rest and peak exercise. Diastolic stress test modalities are passive leg raise (leg raise), fluid challenge (fluid), dynamic handgrip (handgrip), bicycle ergometry (ergo).

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Exercise Pulmonary 40

European Journal of Heart Failure

OCTOBER 30, 2023

The prevalence of select electrocardiographic (ECG) measurements ( left panel ) and the relationship between contiguous pathologic Q waves and sex on clinical outcomes ( right panel ). CI, confidence interval; CV, cardiovascular; HF, heart failure; ICD, implantable cardioverter-defibrillator; LBBB, left bundle branch block; MAGGIC, Meta-Analysis Global Group in Chronic Heart Failure.

Heart Failure 40

Heart Failure Outcomes Defibrillator Research 40

European Journal of Heart Failure

OCTOBER 30, 2023

Among 777 participants who received a COVID-19 mRNA-1273 booster vaccination, 40 (5.1%; 95% confidence interval [CI] 3.7–7.0%) had an elevated high-sensitivity cardiac troponin T (hs-cTnT) concentration on day 3, of whom 22 (2.8% [95% CI 1.7–4.3%]) were adjudicated as mRNA-1273 vaccine-associated myocardial injury. Females ( n  = 20, 3.7% [95% CI 2.3–5.7%]) had a higher incidence than males ( n  = 2, 0.8% [95% CI 0.1–3.0%]).

COVID-19 40

COVID-19 Hospital Research Article 40