Thu.Oct 24, 2024

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Ozempic Linked With Lower Risk of Alzheimer's Diagnosis

Med Page Today

(MedPage Today) -- Semaglutide (Ozempic) was tied to a reduced risk of Alzheimer's disease diagnoses in people with type 2 diabetes, observational data showed. In emulation target trials involving more than 1 million eligible diabetes patients.

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Study offers ‘compelling evidence’ for continuous stroke care improvement

American Heart News - Stroke News

Research Highlights: A retrospective look at Get With The Guidelines® - Stroke registry data from 2003 to 2022 finds substantial and sustained improvements in acute stroke care among those in the quality improvement program. Researchers found.

Stroke 109
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Hospitals with the highest, lowest 30-day mortality rates for coronary bypass

Becker's Hospital Review - Cardiology

Manhasset, N.Y.-based North Shore University Hospital had the lowest 30-day mortality rate for coronary artery bypass graft patients in the U.S. between July 1, 2020, and June 30, 2023, according to CMS data released July 31.

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The value of Age-adjusted Charlson and Elixhauser-Van Walraven comorbidity index in predicting prognosis for patients undergoing heart valve surgery

Journal of Cardiothoracic Surgery

This study aims to compare the efficacy of the Age-adjusted Charlson Comorbidity Index (ACCI) and the Elixhauser-Van Walraven Comorbidity Index (ECI-VW) in predicting mortality risk among patients undergoing h.

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DUPLEX: Sparsentan Could Offer Greater Benefit in Genetic FSGS

HCPLive

A posthoc analysis of the DUPLEX trial suggests patients with genetic FSGS may experience a more pronounced and sustained antiproteinuric response with sparsentan.

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Conventional computer ECG algorithm misses another potentially deadly abnormality. How does AI perform?

Dr. Smith's ECG Blog

Written by Pendell Meyers A woman in her 70s with with multiple medical comorbidities began to have episodes of weakness and pre-syncope off and on for several days, then suffered three episodes of syncope within a few hours. She was brought to an Emergency Department for evaluation. On arrival she was awake, alert, and asymptomatic, with normal vital signs except for heart rate in the low 50s.

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Allen C. Ho, MD: Efficacy, Safety of MCO-010 for Retinitis Pigmentosa at 2 Years

HCPLive

At AAO 2024, HO described meaningful BCVA improvements in patients with retinitis pigmentosa observed through 2 years of the Phase 2b/3 RESTORE trial.

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AI model can predict health risks, including early death, from electrocardiograms

Medical Xpress - Cardiology

A new AI model can predict patients' risk of developing and worsening disease, and even their risk of early death, using an electrocardiogram (ECG).

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Obinutuzumab Reduced Proteinuria, Improved eGFR in FSGS

HCPLive

Overall, 8 of 20 patients had complete or partial remission of their FSGS.

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New formation of neurons from stem cell niche disrupted after stroke

Science Daily - Stroke

Researchers studied what happens immediately after a stroke in the stem cell niche known as the subventricular zone, using a mouse model. This revealed a mechanism that results in fewer newborn neurons from the stem cell niche surviving after stroke, thereby significantly limiting the neurogenic reaction of the subventricular zone to repair the brain.

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Recurrent UTIs Could Damage Kidneys, Even Without Apparent Scarring

HCPLive

RIVUR analysis suggests recurrent UTIs in children with VUR may lower eGFR, even without kidney scarring, especially in those with multiple febrile infections.

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Webinars as a Continuous Medical Education Option in the Era of Advancing Technology

ADN Center of Excellence

In an era defined by rapid technological advancement, continuous medical education (CME ) has evolved dramatically to meet the demands of the healthcare landscape. This evolution, especially since the onset of virtual learning, has underscored the importance of accessible, up-to-date, and flexible education for medical professionals. Webinars, in particular, have emerged as a powerful tool in CME , offering unprecedented convenience, cutting-edge insights, and real-time interactions.

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Environmental sustainability in cardiovascular practice: current challenges and future directions

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 October 2024; doi:10.1038/s41569-024-01077-z In this Review, Rajagopalan and colleagues summarize the sources of greenhouse gas emissions related to the provision of cardiovascular health care and suggest strategies to reduce carbon emissions and costs, including the use of renewable energy, waste reduction and disease prevention.

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Creative Treatment Options for Dermatology Practice, with Elizabeth Swanson, MD

HCPLive

This talk was titled ‘Heard About It, Did It, Now it's Part of My Practice,’ during which Swanson highlighted creative options for conditions such as guttate psoriasis and pyogenic granulomas.

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8 notes on cardiac arrest mortality in EDs

Becker's Hospital Review - Cardiology

Payer status, income and age all had an increased association with mortality for patients seeking treatment for cardiac arrest at emergency departments, according to a study published Sept. 20 in the Journal of Clinical Medicine.

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Webinars as a Continuous Medical Education Option in the Era of Advancing Technology

ADN Center of Excellence

In an era defined by rapid technological advancement, continuous medical education (CME ) has evolved dramatically to meet the demands of the healthcare landscape. This evolution, especially since the onset of virtual learning, has underscored the importance of accessible, up-to-date, and flexible education for medical professionals. Webinars, in particular, have emerged as a powerful tool in CME , offering unprecedented convenience, cutting-edge insights, and real-time interactions.

Webinar 52
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Estudio ofrece ‘evidencia contundente’ para la mejora continua en la atención de derrames cerebrales

American Heart News - Stroke News

Puntos destacados de la investigación: Un análisis retrospectivo del registro Get With The Guidelines® – Stroke, desde 2003 hasta 2022, revela mejoras sustanciales y sostenidas en la atención de derrames cerebrales agudos entre quienes participan en.

Stroke 52
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Systematic identification of therapeutic targets for coronary artery calcification: an integrated transcriptomic and proteomic Mendelian randomization

Frontiers in Cardiovascular Medicine

BackgroundCoronary artery calcification (CAC) is associated with an increased risk of mortality and cardiovascular events. However, none therapeutic drugs have been proven effective for CAC treatment. The objective of this study was to identify potential therapeutic targets for CAC through the utilization of Mendelian randomization (MR) and colocalization analysis.MethodsThe expression quantitative trait loci (eQTLs) of 16,943 genes from the eQTLGen consortium and protein quantitative trait loci

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Ask The Expert

ECG Guru

Is there a quick and easy way to screen for limb lead wire misplacement? Today's Expert is Dr Jerry W. Jones, MD, a long-time contributer to the ECG Guru. Dr Jones is known for his Master Classes in Advanced ECG Interpretation and his published texts, Getting Acquainted With Wide Complex Tachycardias, Getting Acquainted With Laddergrams, and Getting Acquainted With Ischemia and Infarction.

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Right anterior thoracotomy vs. upper hemisternotomy for aortic valve replacement with Perceval S: is there a difference?

Frontiers in Cardiovascular Medicine

BackgroundOur study aimed to evaluate the early outcomes of aortic valve replacement with Perceval S sutureless valve through the right anterior thoracotomy and upper hemisternotomy approaches, and to determine if there are any differences between these two approaches.MethodsWe carried out a study using data from 174 patients who underwent minimally invasive Perceval S valve implantation for aortic valve stenosis between January 2018 and August 2023.

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Philips, Medtronic Partner on Stroke Care Advocacy

DAIC

tim.hodson Thu, 10/24/2024 - 11:57 Oct. 24, 2024 – Royal Philips and Medtronic Neurovascular have announced a strategic advocacy partnership. Delivering timely stroke care is crucial to saving lives and reducing long-term disability. As leaders in stroke diagnosis and treatment, the two organizations are advocating on raising awareness around the potential health and economic benefits for patients, their families and societies of improving access to timely stroke diagnosis and treatment.

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Peyton Manning, Cincinnati Children's hospitals name heart surgery leader

Becker's Hospital Review - Cardiology

Cincinnati Children's and Indianapolis-based Peyton Manning Children's Hospital at Ascension St. Vincent have jointly appointed Roosevelt Bryant III, MD, chief of pediatric and congenital heart surgery.

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A book on Nobel laureates in medicine : An Inspirational journey in the annals of medical science

Dr. S. Venkatesan MD

This was an after thought post retirement from Madras medical college. It used to be intense academic sessions those days. Occasionally and intentionally we make it a point to deviate, to general topics.Used to ask my fellows (every new batch) to tell at least three Nobel prize winners related to cardiology or in medicine.I would see the obvious difficulty in their face.

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Psychology Referrals Rose for Children with Food Allergies in the Past Decade

HCPLive

Psychology referrals for children with food allergies surged 11-fold in the last decade, but many still face limited access to therapy services due to geographic barriers.

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National Costs for Cardiovascular-related Hospitalizations and Inpatient Procedures in the United States, 2016-2021

The American Journal of Cardiology

Publication date: Available online 23 October 2024 Source: The American Journal of Cardiology Author(s): Amier Haidar, Aryan Gajjar, Rushi V. Parikh, Peyman Benharash, Gregg C.

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What to Look Forward To at the Fall Clinical Dermatology Conference, with Raj Chovatiya, MD, PhD

HCPLive

In this interview with Chovatiya, he highlights some of the elements of the presentations being given at the Fall Clinical Dermatology conference in Las Vegas.

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Role of autophagy in myocardial remodeling after myocardial infarction

Journal of Cardiovascular Pharmacology

Autophagy is the process of reusing the body’s senescent and damaged cell components, which can be regarded as the cellular circulatory system. There are three distinct forms of autophagy: macro-autophagy, micro-autophagy, and chaperone-mediated autophagy. In the heart, autophagy is regulated mainly through mitophagy due to the metabolic changes of cardiomyocytes caused by ischemia and hypoxia.

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James Del Rosso, DO: Discussing What’s New in the Medicine Chest for Dermatologists

HCPLive

In the first part of his Fall Clinical presentation on new topical medications, Del Rosso discusses new therapies available for use among dermatologists.

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Evaluating low follow-up rates for individuals with dyslipidemia

Medical Xpress - Cardiology

If untreated, dyslipidemia, especially high levels of LDL cholesterol ("bad" cholesterol), increases the risk of myocardial infarction, cerebral infarction, and dementia. Therefore, it is crucial to visit a medical institution and take appropriate measures when dyslipidemia is detected during a health checkup.

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Raj Chovatiya, MD, PhD: Pathophysiology, Diagnosis of Chronic Hand Eczema

HCPLive

At the Fall Clinical Dermatology conference, Chovatiya presented on chronic hand eczema and facts about its pathophysiology, diagnosis, and management.

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Long-Term Effects of Empagliflozin in Patients with Chronic Kidney Disease

The New England Journal of Medicine

Two years of empagliflozin slowed kidney disease progression or cardiovascular death. In this post-trial study, empagliflozin had additional cardiorenal benefits after discontinuation.

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Anaphylm Sublingual Film Achieves Rapid Resolution of Allergen-Related Symptoms

HCPLive

Aquestive Therapeutics plans to submit an NDA for Anaphylm in Q1 2025 based on topline results from the Oral Allergy Syndrome challenge study.

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Nonalcoholic Fatty Liver Disease Is Associated with Ventricular Arrhythmias and Major Cardiovascular Events in Patients with Implantable Cardioverter-defibrillators

HeartRhythm

Patients with nonalcoholic fatty liver disease (NAFLD) are at risk for cardiovascular diseases. Less is known about the relationship between NAFLD, ventricular arrhythmias (VAs), and cardiovascular events.

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Clinical Quiz: ACG Alcohol-Associated Liver Disease Guideline

HCPLive

Test your knowledge of the 2024 American College of Gastroenterology alcohol-associated liver disease guidelines with this clinical quiz!

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Efficacy of the peak frequency map for left atrial posterior wall isolation

Journal of Cardiovascular Electrophysiology

Abstract Introduction Complete isolation of the left atrial posterior wall (LAPW) is challenging owing to overlapping epicardial conduction. Peak frequency (PF) is a novel parameter that focuses on near- and far-field electrogram components. In this study, we aimed to determine whether transmural block completion is related to the ablation site PF. Methods We analyzed 44 consecutive patients undergoing initial LAPW isolation (LAPWI) between June 2023 and February 2024.

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Symptoms of Anxiety and Depression in Patients Undergoing Transcatheter Aortic Valve Implantation – The SAD-TAVI Study

The American Journal of Cardiology

Publication date: Available online 23 October 2024 Source: The American Journal of Cardiology Author(s): Anant D Butala, Kartik Sehgal, Ellen Gardner, Dion Stub, Sonny Palmer, Samer Noaman, Liam Guiney, Nay M Htun, Rozanne Johnston, Antony S.

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Atherosclerosis Burden and Progression on Imaging and Associated Mortality in Asymptomatic Patients

NEJM Journal Watch - Cardiology

Any atherosclerotic plaque is bad, and its presence portends a worse prognosis if modifiable risk factors like hypertension and smoking are not addressed.