Fri.May 24, 2024

article thumbnail

FLOW Trial Fortifies Semaglutide's Role in Chronic Kidney Disease and Type 2 Diabetes

HCPLive

Semaglutide 1.0 mg reduced major kidney disease events and slowed eGFR decline in patients with type 2 diabetes and chronic kidney disease, according to the FLOW trial.

article thumbnail

Understanding a broken heart

Science Daily - Heart Disease

The stress of heart failure is remembered by the body and appears to lead to recurrent failure, along with other related health issues, according to new research. Researchers have found that heart failure leaves a 'stress memory' in the form of changes to the DNA modification of hematopoietic stem cells, which are involved in the production of blood and immune cells called macrophages.

article thumbnail

Ozempic Protects Kidneys, Boosts Survival in Diabetes Patients With CKD

Med Page Today

(MedPage Today) -- For people with type 2 diabetes and chronic kidney disease (CKD), semaglutide (Ozempic) reduced the risk of major kidney events and death from cardiovascular causes, the phase III FLOW trial showed. Added to usual care, the.

Diabetes 116
article thumbnail

Instructors' Collection ECG: Wide Complex Tachycardia

ECG Guru

The Patient: A 78-year-old woman called emergency responders because she had palpitations. She was alert and oriented. Her BP was reported as being “stable”. We do not have information about her past medical history. We will update this post if we receive information about her outcome. ECG Number 1, 11:57 a.m.: There is a wide-complex tachycardia at a rate of about 230 bpm.

article thumbnail

Continuous Glucose Monitor (CGM): Essential Insights for Pregnancy and Across the Lifespan 

Cardiometabolic Health Congress

As we near the end of National Women’s Health Awareness Month, at CMHC , we want to bring attention to the important discussion of continuous glucose monitoring (CGM) during pregnancy and across the lifespan. CGM offers continuous, real-time glucose readings around the clock, surpassing traditional methods like HbA1C measurements and blood finger sticks.

article thumbnail

How To Reverse Diabetes.

Dr. Paddy Barrett

In the US, over 45% of the population has either diabetes or pre-diabetes 1. The absolute majority of those with diabetes have type 2 diabetes, which is usually associated with excess visceral fat and poor cardiometabolic health. This is not good. Why? Because a diagnosis of diabetes is very likely to shorten your life. A diagnosis of type 2 diabetes at age 30 can result in a 14 to 16-year shorter lifespan 2.

article thumbnail

Congressman's Stroke; Warning on Bear Meat Consumption; Paralysis via Grand Piano

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Also note that in observance of the Memorial Day holiday, our Morning Break feature will not appear on Monday. Look for its return on Tuesday, May 28. U.S. Representative.

Stroke 98

More Trending

article thumbnail

FDA Advisors Not Convinced Once-Weekly Insulin Is Safe in Type 1 Diabetes

Med Page Today

(MedPage Today) -- An FDA advisory committee mostly agreed on Friday that an investigational once-weekly insulin product carries too much risk for use in adult patients with type 1 diabetes to recommend approval in this patient population. In.

article thumbnail

Key Clinical Considerations in HIV Treatment Decisions

HCPLive

The panel offers expert perspectives on key factors that inform treatment decisions for patients with HIV.

97
article thumbnail

Aortic Valve Calcification in Low-Gradient Aortic Stenosis

American College of Cardiology

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

article thumbnail

Biomarkers in COPD

HCPLive

Igor Barjaktarevic, MD, PhD, provides insights on the evolving role of biomarkers in COPD, highlighting the role of eosinophils on informing treatment decisions.

article thumbnail

Microvascular Resistance Reserve After Primary PCI

American College of Cardiology

What is the prognostic value of microvascular resistance reserve (MRR) in patients with ST-segment elevation myocardial infarction (STEMI), and how does MRR compare with cardiac magnetic resonance (CMR) imaging parameters of microvascular resistance?

article thumbnail

Strategies for Better Identification and Management of Osteoporosis, with E. Michael Lewiecki, MD

HCPLive

HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more.

59
article thumbnail

Functional Assessment in Elderly MI Patients With Multivessel Disease

American College of Cardiology

The goal of the FIRE trial was to evaluate multivessel revascularization guided by coronary physiology compared with culprit-only revascularization among elderly patients with acute myocardial infarction (MI) and multivessel coronary artery disease (CAD).

article thumbnail

Insights Gleaned from Asthma Research for COPD

HCPLive

1) Nicola A. Hanania, MD, MS, discusses what we have learned from asthma research on the involvement of type 2 inflammation that is applicable to COPD.

article thumbnail

AI May Help Physicians Detect Abnormal Heart Rhythms Earlier

DAIC

milla1cf Fri, 05/24/2024 - 07:00 May 24, 2024 — An artificial intelligence (AI) program developed by investigators in the Smidt Heart Institute and their Cedars-Sinai colleagues can detect a type of abnormal heart rhythm that can go unnoticed during medical appointments, according to a new study. The study’s findings, published in npj Digital Medicine , suggest AI could one day be employed to analyze images from a common imaging test called an echocardiogram, which uses sound waves to captur

article thumbnail

ORION-8: Inclisiran Displays Sustained LDL-C Lowering Over Long-Term

HCPLive

ORION-8 demonstrates the consistent long-term efficacy and tolerability of twice-yearly inclisiran over a mean cumulative exposure of 3.7 years.

64
article thumbnail

Physiology Friday #219: Could a Low-Carb Ketogenic Diet Harm Bone Health in Endurance Athletes?

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Diet 52
article thumbnail

Approaches to AxSpA Management, with Nigil Haroon, MD, PhD

HCPLive

Nigil Haroon, MD, PhD, explains how understanding the "window of opportunity" is crucial in treating axial spondyloarthritis.

59
article thumbnail

ACC CardiaCast: Pulse Check: Social Support

American College of Cardiology

In this episode, Andrea Price, MS, AACC hosts Jill Steiner, MD, MS, FACC, and Rosy Thachil, MD, FACC for a discussion on the importance of social support and its role in promoting good mental health, especially among people with a chronic illness like heart disease.

article thumbnail

Prashant Singh, MD: Rethinking the Low FODMAP Diet for IBS-D

HCPLive

Singh explains a potential new approach to the low FODMAP diet based on findings from research he presented at DDW suggesting a simplified step-up method.

Diet 52
article thumbnail

A Modular Communicative Leadless Pacing–Defibrillator System

American College of Cardiology

Is a novel modular pacing–defibrillator system, consisting of a leadless pacemaker in wireless communication with a subcutaneous implantable cardioverter–defibrillator (ICD), able to effectively and safely provide antitachycardia and bradycardia pacing?

article thumbnail

Elizabeth Aby, MD: Financial Burden in Adults Undergoing Liver Transplant Evaluation

HCPLive

Aby describes findings from a pair of studies presented at DDW exploring the prevalence and impact of financial burden in liver transplant candidates.

article thumbnail

Randomized Controlled Trial of Intravascular Imaging Guidance Versus Angiography-Guidance on Clinical Outcomes After Complex Percutaneous Coronary Intervention

American College of Cardiology

The goal of the RENOVATE-COMPLEX-PCI trial was to evaluate intravascular imaging-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI among patients with complex coronary artery disease.

article thumbnail

Sean Adrean, MD: Impact of Baseline VA on Aflibercept 8 mg Outcomes in DME

HCPLive

Aflibercept 8 mg exhibited clinically meaningful visual, anatomic improvements at Week 48 in patients with DME regardless of baseline visual acuity.

article thumbnail

Stroke Risk After Mitral Valve Interventions: A Systematic Review and Network Meta-Analysis

The American Journal of Cardiology

Publication date: Available online 23 May 2024 Source: The American Journal of Cardiology Author(s): Sina Kazemian, Kannu Bansal, Toshiki Kuno, Tanush Gupta, Kashish Goel, Sahil Khera, Mohamad Alkhouli, Dhaval Kolte

article thumbnail

Initial eGFR Dip Can Help Predict Proteinuria Reduction with SGLT2i in IgA Nephropathy

HCPLive

New study finds SGLT2 inhibitors reduce proteinuria in IgA nephropathy, with greater initial eGFR dips predicting stronger treatment responses.

52
article thumbnail

Heart failure learning module 1: background, epidemiology, aetiology and pathophysiology

The British Journal of Cardiology

Designed to give healthcare professionals an understanding of the epidemiology and pathophysiology of heart failure (HF). It is one of several modules in our heart failure programme.

article thumbnail

Brian Lacy, MD, PhD: Assessing, Treating Chronic Abdominal Bloating and Distension

HCPLive

Lacy reviews key considerations for the diagnostic evaluation and treatment of abdominal bloating and distension based on his session at DDW.

52
article thumbnail

Heart failure learning module 3: lifestyle modifications and pharmacological treatment of heart failure

The British Journal of Cardiology

Introduction The aims of chronic heart failure (HF) management are: to provide symptom relief to prevent hospitalisation for HF to improve survival. Optimal pharmacological and non-pharmacological management (including device treatment) have had an enormous beneficial impact on the clinical course of HF. This module will focus on lifestyle modifications and pharmacological treatment.

article thumbnail

Immune-Mediated Inflammatory Diseases like RA Linked to Severe COVID-19 Outcomes

HCPLive

Age, chronic comorbidities, and COVID-19 vaccination status in patients with IMIDs serve as risk factors for severe COVID-19 outcomes.

article thumbnail

Age-associated declined function of endothelial progenitor cells and its correlation with plasma IL-18 or IL-23 concentrations in patients with ST-segment elevation myocardial infarction

Frontiers in Cardiovascular Medicine

BackgroundST-segment elevation myocardial infarction (STEMI) persists to be prevalent in the elderly with a dismal prognosis. The capacity of endothelial progenitor cells (EPCs) is reduced with aging. Nevertheless, the influence of aging on the functionality of EPCs in STEMI is not fully understood.MethodThis study enrolled 20 younger STEMI patients and 21 older STEMI patients.

article thumbnail

Algorithms Predict Cardiovascular Risk for Patients with PsA

HCPLive

Combining algorithms SCORE2 and QRISK3 created the best predictive model to predict the cardiovascular risk for patients with PsA.

52
article thumbnail

Heart failure module 6: commonly encountered complications in HF

The British Journal of Cardiology

Designed to give healthcare professionals an understanding of the clinical significance and treatment of electrolyte abnormalities and anaemia in patients with heart failure.

article thumbnail

HIV Treatment: Discussing Adverse Events with Patients

HCPLive

Experts on the treatment of HIV discuss how they talk with their patients about adverse effects associated with HIV regimens.

52
article thumbnail

Heart failure module 5: surgical management and palliative care of HF

The British Journal of Cardiology

Designed to give healthcare professionals an understanding of surgical methods to manage heart failure. It is one of several modules in our heart failure programme.

article thumbnail

ROXSTAR Registry Offers Insight into Effects of Roxadustat in Real-World Settings

HCPLive

Study finds roxadustat effectively treats anemia in both dialysis-dependent and non-dialysis-dependent CKD patients.

52