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Researchers have used mathematical analysis tools to study the effect of classical music on a fetal heartbeat and identify patterns in heart rate variability. They recruited 36 pregnant women and played two classical pieces for their fetuses. By attaching external heart rate monitors, the researchers could measure the fetal heart rate response to both songs, and by employing nonlinear recurrence quantification analysis, they could identify changes in heart rate variability during and after the m
Dyslipidemia is extensively analyzed in clinical trials investigating its role as a risk factor for coronary artery disease (CAD). However, its definition varies vastly among studies, leading to different attributions to the variable dyslipidemia. The objectives of this study are to verify the hypothesis of a lack of a consensual definition of dyslipidemia in coronary angiography studies and to propose a consensual definition of dyslipidemia, considering the influence of each serum lipid paramet
Background Left ventricular diastolic function as assessed by tissue Doppler echocardiography predicts cardiovascular event rates at 4 years of follow-up in patients with hypertension. Our aim was to evaluate whether this extends to predicting cardiovascular mortality after 20 years of follow-up. Methods Conventional (E) and tissue Doppler (e') echocardiography was performed on hypertensive participants in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) with long-term follow-up ascertained
ObjectiveTo explore the risk factors for cardiotoxicity in patients with gastrointestinal (GI) tumors treated with fluorouracil drugs.MethodsThis study included patients with GI tumors who received fluorouracil at our hospital between January 2018 and April 2022. The demographic and clinical characteristics were collected. The risk factors associated with the cardiotoxicity of fluorouracil were explored using multivariable logistic regression.ResultsA total of 300 patients were finally included
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Methods This work was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Full text research articles discussing clinical or cost-effectiveness aspects of Inspiris Resilia bioprosthesis published in English were included in this analysis.
The exact role of subcutaneous adipose tissue in the interplay between type 2 diabetes (T2D) and coronary artery disease (CAD) is yet to be determined. A prospective cohort study of adult patients with and without T2D undergoing CABG was performed. Subcutaneous adipose tissue was collected during the procedure and RNA seq analysis was performed. A total of 741 differentially expressed genes (DEGs) were identified (332 up- and 409 down-regulated in the T2D group).
tim.hodson Tue, 02/04/2025 - 17:13 Feb. 3, 2025 Today, Peripheral Artery Disease (PAD)affects 10 million Americans and is the most common cause of limb amputation outside of trauma. Yet, 70 percent of Americans dont know what it is or what signs to look for. During American Heart Month, the PAD Pulse Alliance, a coalition of four leading medical societies dedicated to improving vascular health, is raising awareness of PAD and providing resources for people to learn more about it.
tim.hodson Tue, 02/04/2025 - 17:13 Feb. 3, 2025 Today, Peripheral Artery Disease (PAD)affects 10 million Americans and is the most common cause of limb amputation outside of trauma. Yet, 70 percent of Americans dont know what it is or what signs to look for. During American Heart Month, the PAD Pulse Alliance, a coalition of four leading medical societies dedicated to improving vascular health, is raising awareness of PAD and providing resources for people to learn more about it.
Post-Cardiac Injury Syndrome (PCIS) refers to a collective term encompassing post-myocardial infarction syndrome, post-pericardiotomy syndrome, and post-traumatic pericarditis. With an aging population, the incidence of PCIS is on the rise annually. This condition is considered to be an autoimmune-mediated inflammatory response leading to pericarditis as the primary manifestation of the cardiac disease.
This cluster randomized clinical trial evaluated if a reduced-sodium, added-potassium salt substitute compared with regular salt decreases the risk of stroke recurrence and death in patients with a history of stroke.
A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart -- an important process for maintaining heart health.
Though a rare condition, acute type A aortic dissection (ATAAD) is associated with high morbidity and mortality; hence, timely diagnosis and surgery are important to reduce the risk of mortality. If the dissection extends into the aortic arch branches, ensuring adequate cerebral perfusion during surgery is crucial to preventing stroke. A 50-year-old man presented to the emergency department with symptoms of acute chest pain, dizziness, and headache.
In heart failure patients with reduced ejection fraction (HFrEF) requiring a pacemaker, biventricular cardiac resynchronisation therapy (CRT) is preferred to right ventricular (RV) pacing. Moreover, HFrEF patients who already have a conventional pacemaker in situ should be considered for CRT upgrade in the presence of worsening symptoms and a significant proportion of RV pacing.
In 2000, Malcolm Gladwell articulated the concept of the tipping point. He explained that many things happen building toward a change without change occurring, until suddenly, some new information takes the idea to the thresholdand the change occurs suddenly. Two studies published in this issue of JAMA Cardiology add in substantial ways to the growing and compelling evidence for the benefit of a lower sodium intake in the general population and in patients with or at high risk for vascular disea
The ULTIMATE-DAPT (One-Month Ticagrelor Monotherapy After PCI in Acute Coronary Syndromes) trial data demonstrated that, in patients with acute coronary syndrome who underwent percutaneous coronary intervention and remained event-free after 1 month of dual antiplatelet therapy (DAPT), ticagrelor monotherapy (month 1 to month 12) resulted in lower bleeding events.
A study found propranolol significantly lowers ischemic stroke risk in women with migraine, highlighting its potential for stroke prevention in high-risk groups.
Journal of the American Heart Association, Ahead of Print. BackgroundWe examined the association between acute cardiovascular disease (CVD) events and wildfire air pollution in California in 2018.MethodsThe study included adult (18 years) members of Kaiser Permanente Northern California, an integrated health care system. Outcomes included CVD events (hospitalizations for acute myocardial infarction, heart failure, or stroke, and CVD death) and death from any cause.
The use of noncigarette tobacco products is associated with considerable cardiovascular risk, as demonstrated by relevant inflammation, thrombosis and atherosclerosis markers, according to a cross-sectional study published Jan. 27.
Drs. Marine and Pathak break down the key clinical takeaways and valuable insights on optimizing AFib management and improving outcomes through evidence-based strategies.
An anomalous origin of the pulmonary artery (AOPA) from the ascending aorta is a relatively rare but important cardiac malformation that frequently involves the right pulmonary artery (RPA). Its clinical manif.
Abnormalities of the coronary arteries, including abnormal origins, are often detected in heart patients who undergo coronary angiography. Although only a small percentage of these abnormalities lead to seriou.
Pneumonectomy, the surgical removal of an entire lung, was first performed in 1933 by Evarts A. Graham for lung carcinoma. Today, pneumonectomy is primarily indicated for non-small cell lung cancer (NSCLC) wor.
"Discover the 11 leaders in stroke research and care who will be honored at the American Stroke Association's International Stroke Conference in February.
(MedPage Today) -- Nationwide data showed that twin pregnancies are associated with a greater risk of cardiovascular disease (CVD) complications in the first year postpartum. (European Heart Journal) The cardiovascular impacts of sleep apnea may.
In a Q&A, Kang discusses the role of MAVS in host resilience, aging as a contributing factor of lung disease, and the link between viral innate immunity and aging biology.
(MedPage Today) -- Body-weight cycling, sometimes referred to as yo-yo dieting, may be harmful to the kidneys for people with type 1 diabetes, according to retrospective data analysis. Among 1,432 people with type 1 diabetes, high variability.
Most deprescribing interventions consist of a clinician being alerted to a potential problem with the patients medication but does not provide guidance to the clinician about how to communicate with the patient.
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