Tue.Dec 19, 2023

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New technologies and medications that can prevent, reduce CVD top 2023 scientific research

American Heart News - Heart News

DALLAS, Dec. 19, 2023 — Technologies that less invasively restore blood flow to blocked or narrowed arteries; a medicine that outsmarts high blood pressure’s development; and new evidence that diabetes drugs may offer heart health benefits to people that.

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Concerning EKG with a Non-obstructive angiogram. What happened?

Dr. Smith's ECG Blog

This is written by Willy Frick, an amazing cardiology fellow in St. Louis. [link] A 62 year old man with a history of hypertension, type 2 diabetes mellitus, and carotid artery stenosis called 911 at 9:30 in the morning with complaint of chest pain. He described it as "10/10" intensity, radiating across his chest from right to left. EMS obtained the following vital signs: pulse 50, respiratory rate 16, blood pressure 96/49.

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Medical Image Sharing App Eliminates CDs & Makes Your Job Easier

NOVARAD

In today's interconnected world, quick and easy access to information is the norm, yet the healthcare sector has sometimes struggled to keep pace. After all, there were once days of using CDs to share essential medical images. It was not only inconvenient but also raised concerns about accessibility and the well-being of patients.

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Tighter Versus Less-Tight Glycemic Treatment Compares Similarly for Gestational Diabetes Mellitus

HCPLive

Tight glycemic target treatment compares similarly to less-tight glycemic target treatment in terms of how it affects the mental health status of women with gestational diabetes mellitus.

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Heart Vest Could Help Predict Sudden Cardiac Death Risk

DAIC

ECGI vest developed at UCL being worn by a UCL medical student. Image courtesy of UCL Institute of Cardiovascular Science / James Tye milla1cf Tue, 12/19/2023 - 18:19 December 19, 2023 — A vest that can map the electrical activity of the heart in fine detail could potentially be used to better identify people at high risk of sudden cardiac death , suggests a new study led by UCL researchers.

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Report: Most Adults Fail to Recognize Diabetes as Cardiovascular Risk Factor

HCPLive

Among adults in middle- to high-income nations, awareness of diabetes as a cardiovascular risk factor remains a persistent issue.

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BioCardia Doses First Patient in CardiALLO Phase I/II Clinical Trial of BCDA-03 Allogeneic Mesenchymal Stem Cells for the Treatment of Ischemic Heart Failure of Reduced Ejection Fraction

DAIC

Getty Images milla1cf Tue, 12/19/2023 - 18:09 December 19, 2023 — BioCardia, Inc. , a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary disease, announced that the first patient was enrolled and treated in its CardiALLO Allogeneic Mesenchymal Cell Therapy Phase I/II trial for the treatment of patients with New York Heart Association Class II and III ischemic heart failure of reduced ejection fraction ( HFrEF ).

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How To Reverse Coronary Artery Disease With Lifestyle Measures

Dr. Paddy Barrett

Reversing or regressing coronary artery disease is possible. You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. But can coronary artery disease be reversed with lifestyle measures, including changes to nutrition and exercise?

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FDA Priority Review Granted to Omalizumab for Adults, Children with Food Allergy

HCPLive

The decision by the FDA is a step closer to omalizumab’s potential approval, making it the potential first medicine to reduce reactions to many different food allergens after accidental exposure.

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Siemens Healthineers Announces FDA Clearance of Somatom Pro.Pulse Dual-Source CT Scanner

DAIC

milla1cf Tue, 12/19/2023 - 17:05 December 19, 2023 — Siemens Healthineers announced the Food and Drug Administration ( FDA ) clearance of the Somatom Pro.Pulse, a dual-source computed tomography scanner designed to be more affordable for a wide range of healthcare facilities, including outpatient diagnostic centers. The scanner combines the power and speed of dual-source CT technology—two X-ray tubes and two detectors—with embedded artificial intelligence and user assistance features to deli

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Psychosocial Outcome Improvement Observed in Diabetes Patients Using Automated Insulin Delivery

HCPLive

Addressing a lack of quantitative data on AID, this study used validated measures in a real-world setting to corroborate the psychosocial benefits seen in prior qualitative research.

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Effect of three-day atorvastatin administration on coagulation factors in patients with prior venous thromboembolism and healthy subjects. A preliminary study.

Journal of Cardiovascular Pharmacology

Statins exert antithrombotic effects, which might contribute to reduced risk of venous thromboembolism (VTE). Rosuvastatin 20 mg/d administered for 4 weeks has been reported to decrease coagulation factors (F) VII, FVIII, and FXI in VTE patients. Moreover, in accordance with recent registry data in non-VTE subjects statins usage was associated with lower FXI.

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Study Details Impact of Pancreas Transplantation on Kidney Function

HCPLive

More than half of patients who received a pancreas transplant alone experienced >50% decline in eGFR, had eGFR < 30 mL/min/1.73 m2, and/or received a kidney transplant 10 years after their initial pancreas transplant.

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Engineered human heart tissue shows researchers the mechanics of tachycardia

Medical Xpress - Cardiology

Heart rates are easier to monitor today than ever before. Thanks to smartwatches that can sense a pulse, all it takes is a quick flip of the wrist to check your heart. But monitoring the cells responsible for heart rate is much more challenging—and it's encouraged researchers to invent new ways to analyze them.

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Acceptance, Commitment Therapy Program Shows Mixed Results for Type 1 Diabetes Patients

HCPLive

While the ACT program did not benefit patients in the study’s primary outcome measure, it did lead to some other benefits for those with type 1 diabetes.

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Ep 189 Commonly Missed and Mismanaged Wrist Injuries

ECG Cases

In this part 1 or our 2-part podcast series on wrist injuries Dr. Arun Sayal and Dr. Matt DiStefano answer such questions as:when should we suspect a DRUJ injury, why is it important to pick up DRUJ injuries in the ED, and how does it change our management? Why is the lateral x-ray view so important in picking up commonly missed wrist injuries? When it comes to distal radius fractures, how are Colles vs Barton's vs Smith's fractures managed differently in the ED?

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Weight Cycling Linked to Fat-Free Mass Loss in People At Risk of Diabetes

HCPLive

Weight cycling could lead to a relative loss of fat-free mass in people living with overweight and obesity at high risk of type 2 diabetes.

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Should Normal Range of Albumin Be Redefined for Cardiovascular Health?

Med Page Today

(MedPage Today) -- Growing evidence points to kidney health as a major contributor to cardiovascular health, with the implication that there should be more testing and treatment for albuminuria starting in the current normal range. The death risks.

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Can decongestants spike your blood pressure? What to know about hypertension and cold medicine

Medical Xpress - Cardiology

It's the season for respiratory viruses and the cough, congestion and sore throats they bring. There are many options for over-the-counter (OTC) remedies and relief, but if you have high blood pressure, you may want to take a closer look at the label. Some may contain warnings that advise against taking if you have high blood pressure. Others contain high levels of sodium, which can also increase blood pressure.

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Cardiac Catheterization Laboratory Management of the Comatose Adult Patient With an Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Out-of-hospital cardiac arrest is a leading cause of death, accounting for ≈50% of all cardiovascular deaths. The prognosis of such individuals is poor, with &lt;10% surviving to hospital discharge. Survival with a favorable neurologic outcome is highest among individuals who present with a witnessed shockable rhythm, received bystander cardiopulmonary resuscitation, achieve return of spontaneous circulation within 15 minutes of arrest, and have evidence of ST-se

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Dual Antiplatelet Therapy De-Escalation After Myocardial Infarction With High Ischemic Risk

JAMA Cardiology

This post hoc analysis of the Ticagrelor vs Clopidogrel in Stabilized Patients With Acute Myocardial Infarction (TALOS-AMI) randomized clinical trial investigates the efficacy and safety of the de-escalation strategy of switching from ticagrelor to clopidogrel vs dual antiplatelet therapy with ticagrelor in stabilized patients with acute myocardial infarction and high ischemic risk.

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Navigating and Communicating about Serious Illness and End of Life

The New England Journal of Medicine

Conversations about prognosis are difficult for patients and clinicians. Clinicians should partner with patients as they integrate prognostic information into goals and end-of-life decisions.

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AHA Update on Resistance Exercise Training: Key Points

American College of Cardiology

The following are key points to remember from an updated American Heart Association (AHA) scientific statement on resistance exercise training in individuals with and without cardiovascular disease (CVD).

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Researchers report detailed analysis of heart injury caused by yellow fever virus

Medical Xpress - Cardiology

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) have studied the pathogenesis of YF-associated heart injury.

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Case Report: Surgical management of idiopathic pulmonary aneurysms and review surgical approaches

Frontiers in Cardiovascular Medicine

Idiopathic pulmonary aneurysm is a clinically rare condition characterized by an unknown etiology and episodic occurrence. Despite its rarity, idiopathic pulmonary artery aneurysm poses potential risks to patients. Currently, there is a lack of established clinical guidelines and consensus regarding its management, leading to ongoing controversies in treatment strategies.

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Maternal Study Satisfaction Increases Visit Compliance in Children at Risk for Diabetes

HCPLive

Maternal characteristics, sociodemographic factors, and paternal participation during the initial year of the TEDDY study were identified as key predictors of enhanced visit compliance in a pediatric cohort genetically predisposed to type 1 diabetes.

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Case Report: A long-term survival case of diffuse large B-cell lymphoma with left ventricular infiltration and spinal cord compression

Frontiers in Cardiovascular Medicine

Background Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and may occur with lymph node and/or extranodal involvement. However, DLBCL with intracardiac mass is exceedingly rare. In the reported literature, the intracardiac infiltration of DLBCL mostly involves the right ventricle. Lymphoma that invades the heart has an aggressive nature, with symptoms that are easily ignored initially and can lead to multiple complications in severe cases, resulting in a

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Apple Halts Watch Sales; FDA Database May Miss Red Flags; Babies' Tongues Cut

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Apple halted sales of certain versions of the Apple Watch in the U.S. amid a patent dispute involving a medical device maker and its blood oxygen feature. (CNN.

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Evaluation of atrial fibrillation using wearable device signals and home blood pressure data in the Michigan Predictive Activity & Clinical Trajectories in Health (MIPACT) Study: A Subgroup Analysis (MIPACT-AFib)

Frontiers in Cardiovascular Medicine

Background The rising adoption of wearable technology increases the potential to identify arrhythmias. However, specificity of these notifications is poorly defined and may cause anxiety and unnecessary resource utilization. Herein, we report results of a follow-up screening protocol for incident atrial fibrillation/flutter (AF) within a large observational digital health study.

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Which Symptoms are Most Burdensome to Patients With AD

HCPLive

Andrea Nguyen, PA, shares which symptoms are most burdensome to patients with AD.

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Hot Topics in Congenital and Pediatric Cardiology in the Year 2023

American College of Cardiology

This year saw exciting developments in the treatment of pediatric and congenital heart disease. Transcatheter pulmonary valve replacement (TPVR) continued to dominate the field of interventional cardiology.

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Semaglutide May Significantly Reduce Systolic Blood Pressure in People with T2D

HCPLive

A review and meta-analysis of 29 studies found systolic blood pressure significantly decreased in the semaglutide group compared with placebo or other active controls.

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Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study

Cardiovascular Diabetology

Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease.

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Maternal Height, Pre-Pregnancy BMI, Weight Gain Affect Adverse Pregnancy Events

HCPLive

Maternal height is linked to specific adverse pregnancy events in women with gestational diabetes mellitus, according to a new study. The investigators found shorter women had higher rates of low birth rate and primary c-sections, but taller women had higher rates of abnormal neonatal ponderal index, postpartum hemorrhage, and macrosomia.

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Novel approach emerging for rescuing limbs at risk

Science Daily - Heart Disease

Scientists identify a population of human progenitor cells that were 100% effective in mouse models at promoting new blood vessel growth and restoring normal blood flow in ischemic limbs at risk of amputation. These cells also were found in high numbers in two human patients after successful treatments in a clinical trial.

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Heart failure causally linked to chronic kidney disease

Medical Xpress - Cardiology

Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE.

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Emerging Agents in the Treatment of Gout

HCPLive

In this discussion, experts focus on emerging treatment options for gout and share tips for monitoring and managing gout in patients with comorbid conditions.

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