Thu.Jan 04, 2024

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Henry Ford Health Cardiologists Publish Case Series Study on Heart Valve Procedure

DAIC

Study investigators Drs. Pedro Engel-Gonzalez and Gennaro Giustino from Henry Ford Health. Image courtesy of Hentry Ford Health milla1cf Thu, 01/04/2024 - 10:55 January 4, 2024 — Findings from a published case series research letter by the Henry Ford Health Structural Heart Disease team show that severe mitral stenosis, due to a build-up of calcium deposits in the mitral valve common in elderly patients, can be safely and successfully treated using Intravascular lithotripsy (IVL)-enabled percuta

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FDA Accepts Biologics License Application for Ustekinumab Biosimilar DMB-3115

HCPLive

BLA submission was based on data from phase 3 clinical trials in which DMB-3115 showed no clinically meaningful differences compared with the reference product for the treatment of plaque psoriasis.

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Fasting Before Cardiac Catheterization May Be Unnecessary

DAIC

Credit: American Association of Critical-Care Nurses milla1cf Thu, 01/04/2024 - 11:00 January 4, 2024 — The days of prolonged fasting prior to cardiac catheterization may be numbered, as the body of evidence grows to allow patients to eat before the procedure. Patients undergoing coronary artery catheterization are typically required to take nothing by mouth after midnight prior to their procedure, but there is no evidence to support this long-standing practice.

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Hearing Loss Linked with Increased Risk of Dementia

HCPLive

In a new study, hearing loss was significantly associated with a 7% higher risk of dementia, while hearing aids were shown to reduce such risks.

Dementia 122
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In Acute Kidney Disease, SGLT2 inhibitors Were All-Around Protective

Med Page Today

(MedPage Today) -- SGLT2 inhibitors significantly lowered the risk of death, major adverse kidney events (MAKE), and major adverse cardiovascular events (MACE) in people with type 2 diabetes and acute kidney disease, according to a cohort study.

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SGLT-2is Mitigate Risk of Cardiovascular, Kidney Diseases in Patients with Type 2 Diabetes and AKD

HCPLive

Compared to nonusers, patients with type 2 diabetes and acute kidney disease administered SGLT-2is had a significantly lower risk of mortality, major adverse kidney events, and major adverse cardiovascular events.

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Florida cardiologists extract heart tumor with catheter

Becker's Hospital Review - Cardiology

HCA Florida Largo Hospital cardiologists were the first in the state to successfully remove a tumor from inside a patient's heart without open heart surgery.

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AI-driven study redefines right heart health assessment with novel predictive model

Medical Xpress - Cardiology

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

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Emerging Agents in The Treatment of Gout

HCPLive

In this discussion, experts focus on emerging treatment options for gout and share tips for monitoring and managing gout in patients with comorbid conditions.

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Study Assuages Fears of Pancreatic Cancer Risk With GLP-1 Receptor Agonists

Med Page Today

(MedPage Today) -- Several years after initiating treatment, GLP-1 receptor agonist users didn't have a pancreatic cancer safety signal, a historical cohort study reported. Compared with basal insulin users, those on a GLP-1 receptor agonist didn.

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Mechanism of Action of Nonstatin Therapies

HCPLive

Dr Kohli gives an overview of the mechanisms of action of non-statin agents for the management of hyperlipidemia.

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Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2

American College of Cardiology

The goal of the STOPDAPT-2 trial was to evaluate 1-month dual antiplatelet therapy (DAPT) compared with 12-month DAPT among patients undergoing percutaneous coronary intervention (PCI).

Stents 75
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The Cumulative Burden of LDL-C

HCPLive

Expert cardiologists discuss the cumulative burden of an elevated cholesterol over time.

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TMS for Psych Disorders Poses Little Threat to Implanted Cardiac Devices

Med Page Today

(MedPage Today) -- An electromagnetic therapy for depression shouldn't damage a person's pre-existing implantable cardioverter-defibrillator (ICD), multiple experiments indicated. There was a low risk of ICD damage or overheating during transcranial.

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Dermatology Month in Review: December 2023

HCPLive

The December 2023 month in review for dermatology covers major stories regarding a new FDA approval, several new treatment findings, and news on attitudes toward those with acne.

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Plasma levels of autophagy regulator Rubicon are inversely associated with acute coronary syndrome

Frontiers in Cardiovascular Medicine

Background The discovery of novel biomarkers that improve current cardiovascular risk prediction models of acute coronary syndrome (ACS) is needed for the identification of very high-risk patients and therapeutic decision-making. Autophagy is a highly conserved catabolic mechanism for intracellular degradation of cellular components through lysosomes.

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Unveiling a Year of Medical Excellence: Celebrating 2023's Milestones and Beyond

ADN Center of Excellence

As we bid farewell to an extraordinary year, we stand in awe of the incredible journey we've embarked upon in 2023. It's with immense pride and joy that we reflect on the milestones and accomplishments achieved by our collective dedication to advancing medical education and innovation. The canvas of 2023 was painted with vibrant hues of knowledge and expertise, marked by a plethora of events and trainings that illuminated the path toward medical excellence.

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A Bayesian network-based approach for identifying risk factors and predicting ischemic stroke in infective endocarditis patients

Frontiers in Cardiovascular Medicine

Objective This study aimed to seek the risk factors and develop a predictive model for ischemic stroke (IS) in patients with infective endocarditis (IE) utilizing a Bayesian network (BN) approach. Methods Data were obtained from the electronic medical records of all adult patients at three hospitals between 1 January 2018, and 31 December 2022. Two predictive models, logistic regression and BN, were used.

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Women, Black men less likely to receive lifesaving heart failure treatments: Study

Medical Xpress - Cardiology

Access to potentially lifesaving heart failure treatments has increased in recent years, but women and Black men remain far less likely to receive them, new research suggests.

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Editorial: Response to cardiac resynchronization therapy

Frontiers in Cardiovascular Medicine

Since the implantation of the first pacemakers in the 1960s, rapid advancements in biomedical technologies have led to the development of Cardiac Resynchronization Therapy (CRT) in the 1990s. Landmark randomized controlled trials conducted in the early 2000s demonstrated the reduction of mortality and morbidity by the use of de novo CRT in heart failure (HF) patients with a reduced ejection fraction (HFrEF) and intrinsic, wide QRS complex. (1,2) Moreover, now evidence on CRT upgrade with hard ou

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Endocrinology Month in Review: December 2023

HCPLive

Our endocrinology month in review spotlights our most popular content from December 2023. Our list of the most popular content from the past month includes the ADA Standards of Care—2024, label updates, a feature from our This Year in Medicine series, and more!

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Identification of hub genes in heart failure by integrated bioinformatics analysis and machine learning

Frontiers in Cardiovascular Medicine

Objective To screen feature genes of heart failure patients through machine learning methods, in order to identify characteristic genes driving heart failure and investigate the progression of heart failure Methods Heart failure patient samples were downloaded from the public database GEO (Gene Expression Omnibus), including the datasets GSE116250, GSE120895, and GSE59867.

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Here’s Why Cardiologists Recommend GEMMS ONE EHR

GEMMS

Amidst the ongoing transformations in the healthcare landscape, cardiologists are increasingly embracing Electronic Health Record (EHR) software to enhance workflow efficiency and elevate the quality of patient care. As we explore the crucial role of EHR software, we will also unravel the reasons behind the surge in popularity of GEMMS ONE among cardiologists.

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Impact of clinical variables on outcomes in refractory cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation

Frontiers in Cardiovascular Medicine

Background In the past two decades, extracorporeal resuscitation (ECPR) has been increasingly used in the management of refractory cardiac arrest (CA) patients. Decision algorithms have been used to guide the care such patients, but the effectiveness of such decision-making tools is not well described. The aim of this study was to compare the rate of survival with a good neurologic outcome of patients treated with ECPR meeting all criteria of a clinical decision-making tool for the initiation of

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Positive Airway Pressure Therapy Increases Leptin Levels for Smokers with OSA

HCPLive

A new study found smoking affects serum leptin levels for patients with obstructive sleep apnea on positive airway pressure therapy. Serum leptin levels increased in 40% of active smokers with obstructive sleep apnea but did not increase in any of the non-smokers.

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A cross-sectional analysis of zinc and copper levels and their relationship to cardiovascular disease risk markers in Qatar biobank participants

Frontiers in Cardiovascular Medicine

Cardiovascular diseases (CVD) are the leading cause of mortality and morbidity worldwide. Dietary intake, particularly zinc (Zn) and copper (Cu) has been strongly associated with CVD. These trace elements play a crucial role in human enzyme activity, suppressing inflammation, catalyzing lipid metabolism enzymes, reducing oxidative stress, and regulating glucose metabolism.

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ACC Announces 2024 Slate of Distinguished Award Winners

American College of Cardiology

The ACC is proud to announce the slate of 2024 Distinguished Award winners – an inspiring group of women and men who have, and continue to, make significant contributions in transforming cardiovascular care and improving heart health around the world.

Article 64
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Rheumatology Month in Review: December 2023

HCPLive

The rheumatology month in review highlights fibromyalgia complexities, lupus advancements, and dietary links to gout for improved management.

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Arrhythmic Mitral Valve Prolapse in Unexplained Cardiac Arrest

American College of Cardiology

What is the prevalence and what are the characteristics of mitral valve prolapse (MVP) in a large cohort of patients with unexplained cardiac arrest (UCA)?

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Unveiling a Year of Medical Excellence: Celebrating 2023's Milestones and Beyond

ADN Center of Excellence

As we bid farewell to an extraordinary year, we stand in awe of the incredible journey we've embarked upon in 2023. It's with immense pride and joy that we reflect on the milestones and accomplishments achieved by our collective dedication to advancing medical education and innovation. The canvas of 2023 was painted with vibrant hues of knowledge and expertise, marked by a plethora of events and trainings that illuminated the path toward medical excellence.

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Pilot Study of Supervised Exercise and Intensive Medical Therapy in Patients with INOCA and Coronary Microvascular Dysfunction

The American Journal of Cardiology

Publication date: Available online 4 January 2024 Source: The American Journal of Cardiology Author(s): Christopher L. Schumann, Zachariah B. Nealy, Roshin C. Mathew, Yang Yang, Pelbreton C. Balfour, Peter W.

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Green Space May Reduce the Risk of Childhood Myopia Development

HCPLive

A new cohort study in China reports suggests the structure of green space decreased the relative risk of myopia among school-aged children.

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Pivotal Investigation of Safety and Efficacy of Drug-Eluting Resorbable Scaffold Treatment-Below the Knee

American College of Cardiology

The goal of the LIFE-BTK trial was to evaluate the use of an everolimus-eluting resorbable scaffold compared with balloon angioplasty among patients with chronic limb-threatening ischemia and infrapopliteal artery disease.

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Hepatology Month in Review: December 2023

HCPLive

Our December 2023 month in review highlights top news in HCV screening, treatment with DAAs, and MASLD risk factors.

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Advanced Magnetic Resonance Imaging (MRI) to Define the Microvascular Injury Driven by Neuroinflammation in the Brain of a Mouse Model of Hypertension

Hypertension Journal

Hypertension, Ahead of Print. BACKGROUND:Hypertension is one of the main risk factors for dementia and cognitive impairment.METHODS:We used the model of transverse aortic constriction to induce chronic pressure overload in mice. We characterized brain injury by advanced translational applications of magnetic resonance imaging. In parallel, we analyzed peripheral target organ damage induced by chronic pressure overload by ultrasonography.

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Positive Results Seen in Orismilast Treatment of Patients with HS

HCPLive

Twice-daily PDE4-inhibition using 10–40 mg of orismilast showed promise though further studies may be necessary to validate these findings.

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Vascular Inflammation and Smooth Muscle Contractility: The Role of Nox1-Derived Superoxide and LRRC8 Anion Channels

Hypertension Journal

Hypertension, Ahead of Print. Vascular inflammation underlies the development of hypertension, and the mechanisms by which it increases blood pressure remain the topic of intense investigation. Proinflammatory factors including glucose, salt, vasoconstrictors, cytokines, wall stress, and growth factors enhance contractility and impair relaxation of vascular smooth muscle cells.