Sat.Mar 22, 2025

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Hypoxia in myocardial infarction and natriuretic peptides

Open Heart

Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of circulating natriuretic peptides and their derivatives. While one of the most critical paradigms in cardiology is that mechanical load increases oxygen consumption, clinical studies on these peptides have neglected the relationship between mechanical stress and oxygen metabolism.

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Nudges for Critical Care Physicians; Rates of Parkinson's Worldwide

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Effects of 1-year exercise in patients with atrial fibrillation: study protocol for the Norwegian Exercise in Atrial Fibrillation (NEXAF) randomised controlled trial

Open Heart

Introduction Atrial fibrillation is the most prevalent sustained arrhythmia worldwide and is expected to increase substantially within the coming years. Although lifestyle changes and risk factor modification are now acknowledged as central components of atrial fibrillation management, the effects of exercise on disease-specific outcomes are still not extensively documented due to few high-quality randomised trials.

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Hereditary Angioedema Patients Face High Rates of Autoimmune Conditions, Allergies

HCPLive

Patients with hereditary angioedema report greater rates of autoimmune diseases, allergies, and asthma than the general population, highlighting key comorbidities.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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MIRACLE2 score validation for neuroprognostication after out-of-hospital cardiac arrest: a district general hospital experience

Open Heart

Introduction and objectives Decision-making regarding prognosticating out-of-hospital cardiac arrest (OHCA) remains challenging at the front door. The MIRACLE2 score provides a simple and practical tool for early neuroprognostication to aid decision-making. The study aims to validate the MIRACLE2 score in a district general hospital (DGH). Material and methods This is a retrospective analysis of the patients with OHCA and return of spontaneous circulation (ROSC) in the community who attended the

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Findings on Topical Steroid Withdrawal Versus Eczema, with Ian Myles, MD, MPH

HCPLive

This interview with Ian Myles, MD, MPH, highlights his teams recent findings on identifying dermatitis related to topical steroid withdrawal (TSW) versus atopic dermatitis.

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The HCPFive: Top News for Healthcare Providers from the Week of 03/16

HCPLive

Our top 5 headlines featured new migraine guidelines, the benefit of automated insulin delivery for type 2 diabetes, and 3 key FDA decisions.

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The Clinical Impact of Surgical Left Atrial Appendage Occlusion During Cardiac Surgery in Sinus Rhythm Patients: A Meta-Analysis

HeartRhythm

The clinical efficacy of surgical occlusion of the left atrial appendage in sinus rhythm patients receiving cardiac surgery remains controversial.

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Addressing the Psychosocial Aspects of GPP Management and the Role of Multidisciplinary Care

HCPLive

Panelists discuss the importance of multidisciplinary care in managing generalized pustular psoriasis (GPP), including collaboration between dermatologists and other specialists, and explore strategies for addressing the psychosocial aspects of treatment to improve overall patient outcomes.

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Identifying Cerebral Spinal Fluid Leaks by Catheter Targeted Dynamic Myelograms with Directed Intrathecal Enhancement Tomography (DIET) Technique

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Ahead of Print.

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The Safety And Effectiveness of Slow Pathway Region Visualization Strategy in Radiofrequency Ablation for Adults with Atrioventricular Nodal Reentry Tachycardia: A Multicenter Retrospective Study

The American Journal of Cardiology

Publication date: Available online 21 March 2025 Source: The American Journal of Cardiology Author(s): Wenchi Guan, Jun Liu, Yanbing Gu, Jianjun Li, Keping Chen, Yan Yao

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Secular trends in types of cardiovascular disease in the West of Scotland

Open Heart

Objective Historical reductions in cardiovascular disease (CVD) due to lifestyle and treatment improvements are now threatened by factors such as increasing obesity and diabetes, but the relative importance of different risk factors varies by CVD condition. This study describes secular trends in CVD events by individual condition from 2012 to 2022. Methods In a cohort of 452 094 Greater Glasgow and Clyde residents aged ≥51 years, linked hospital admission and death data were used to ascert

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Sex difference of genetic risk in the prevalence of atrial fibrillation

HeartRhythm

Early detection and management of atrial fibrillation (AF) are crucial. Combined models incorporating genetic risks and clinical risks have been developed to improve predictive ability. Although sex differences have been reported in many aspects of AF, sex differences in genetic risk have not been studied.

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ECG Blog #474 — "Please Believe Me & My ECGs"

Ken Grauer, MD

The ECG in Figure-1 is from a man in his 60s who presented to the ED ( E mergency D epartment ) for new-onset CP ( C hest P ain ). The patient reported intermittent CP for the past 2-3 days prior to this episode. Tonight's epsiode began ~1 hour prior to arrival in the ED. His CP severity =10/10 at the time the ECG in Figure-1 was recorded. QUESTION: In view of the above history: How would you interpret the initial ECG in Figure-1 ?

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Why do so many believe Covid was a plandemic?

Dr. Malcolm Kendrick

This is primarily a matter of trust and the lack of it. If it looks like a conspiracy, and quacks like a conspiracy or, to change focus slightly to Covid. If it looks like 1984, and quacks like 1984 its probably 1984. What happened with Covid I found extraordinary and scary. Within a very short time, longstanding individual rights and freedoms which people fought and died for, over hundreds of years, had gone.

COVID-19 101
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Role of IL-36 in GPP Pathogenesis and Treatment

HCPLive

Panelists describe the role of the IL-36 pathway in the pathogenesis of generalized pustular psoriasis (GPP) and discuss how IL-36 inhibition can be a key strategy in managing the disease.

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