Mon.Oct 14, 2024

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Type 2 Diabetes Diagnoses Emerge in Teens Months After COVID

Med Page Today

(MedPage Today) -- Children and teens had an increased risk of being diagnosed with type 2 diabetes after COVID-19 infection, a retrospective cohort study of over 600,000 youth suggested. Adolescents 10 to 19 years old had a 55% higher risk for.

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Women with Little to No Migraine Disability Had a Lower Quality of Life Than Men

HCPLive

A study found that migraine-related disability worsens health-related quality of life, with gender-specific differences, particularly affecting women with mild disability.

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Six proteins implicated in early-onset preeclampsia

Science Daily - Heart Disease

Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, and it is difficult to predict, prevent and diagnose. Now researchers report on six proteins that could be used as targets to diagnose and treat the condition.

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Risankizumab Demonstrates Efficacy in Treating Individuals with Palmoplantar Psoriasis

HCPLive

In this analysis, the investigators sought to assess the efficacy and safety of risankizumab compared to placebo for patients with palmoplantar psoriasis.

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Hospitals with highest, lowest 30-day mortality rates for heart attack patients

Becker's Hospital Review - Cardiology

New York City-based NYU Langone hospital had the lowest 30-day mortality rate for heart attack patients in the U.S. between July 1, 2020 and June 30, 2023, according to CMS data released July 31.

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Online Tool Developed to Improve Diagnostic Skills of Non-Dermatologists for Psoriasis

HCPLive

This online diagnostic tool’s implementation among study participants led to increased confidence in making diagnoses of chronic plaque psoriasis.

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What Hands-On Training Programs Are Required for Doctors?

ADN Center of Excellence

In today’s fast-paced medical world, keeping up with the latest techniques and technologies is no longer a luxury for healthcare professionals it’s a necessity. This is where hands-on training programs come into play, serving as a critical component in the professional development of doctors across various specialties. At ADN Center of Excellence , we recognize that practical, experiential learning is vital for enhancing procedural expertise and improving patient outcomes.

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Cassling Partner Echo IQ Secures FDA Clearance for EchoSolv AS

Cassling

510(k) clearance secured from FDA allows for EIQ’s AI-enabled solution, EchoSolv AS, to be marketed and sold in the USA Clearance marks a major milestone and will allow for rapid commercial scale-up EIQ is in advanced discussions with a range of US healthcare providers around the potential uptake of EchoSolv AS Working alongside US consultancy to obtain reimbursement codes for the use of EchoSolv AS under insurance to scale up following FDA clearance Sydney: AI and Medical Technology company Ech

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1st COVID wave infections tied to stroke, heart attack risks

Becker's Hospital Review - Cardiology

People who had a confirmed case of COVID-19 during the pandemic's first wave have twice the risk of heart attack, stroke and death compared to those who were never infected, according to research funded by the National Institutes of Health.

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Etanercept, Infliximab Biosimilars Not Linked to Greater Infection Risks

HCPLive

Patients with IBD or arthritis were not found to be at a significantly higher risk of serious infection with a biosimilar versus originator of the common drugs.

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Do Lipid Values in Adolescence Improve CVD Risk Prediction?

Med Page Today

(MedPage Today) -- Non-laboratory-based risk factors and lipids measured in adolescence independently predicted adult cardiovascular events, according to data from seven longitudinal cohort studies. In a multivariable model using non-laboratory.

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FDA Approves Ustekinumab (STELARA) Biosimilar for Chronic Inflammatory Diseases

HCPLive

The ustekinumab biosimilar will be available in early 2025, with indications to treat psoriasis, psoriatic arthritis, Crohn's disease and ulcerative colitis.

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Case Report: Massive intrapericardial hematoma following acupuncture therapy

Frontiers in Cardiovascular Medicine

Cardiac tamponade is a critical cardiovascular condition where timely diagnosis and treatment are crucial. The formation of an intrapericardial hematoma following acupuncture therapy is clinically rare. This paper reports a case of an elderly female patient who experienced severe chest pain and syncope during acupuncture therapy, subsequently diagnosed with traumatic hemopericardium and acute cardiac tamponade, complicated by cardiogenic shock.

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Heart failure and major haemorrhage in people with atrial fibrillation

Open Heart

Background Heart failure (HF) is not included in atrial fibrillation (AF) bleeding risk prediction scores, reflecting uncertainty regarding its importance as a risk factor for major haemorrhage. We aimed to report the relative risk of first major haemorrhage in people with HF and AF compared with people with AF without HF (‘AF only’). Methods English primary care cohort study of 2 178 162 people aged ≥45 years in the Clinical Practice Research Datalink from January 2000 to Dece

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Usefulness of C-reactive protein-triglyceride glucose index in detecting prevalent coronary heart disease: findings from the National Health and Nutrition Examination Survey 1999–2018

Frontiers in Cardiovascular Medicine

BackgroundCoronary heart disease (CHD) is one of the leading causes of mortality. The current study aims to assess the association between C-reactive protein-triglyceride glucose index (CTI) and the risk of prevalent CHD and to evaluate the usefulness of CTI to refine the identification of prevalent CHD.Methods19,451 subjects from the National Health and Nutrition Examination Survey 1999–2010 were enrolled.

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Predictors of death without prior appropriate therapy in ICD recipients: the comorbidities, frailty and functional status (COMFFORT study)

Open Heart

Objective Most patients who have an implantable cardioverter-defibrillator (ICD) implant do not receive life-prolonging therapy from it. Little research has been undertaken to determine which patients benefit the least from ICD therapy. As patients age and accumulate comorbidities, the risk of death increases and the benefit of ICDs diminishes. We sought to evaluate the impact of comorbidity, frailty, functional status on death with no prior appropriate ICD therapy.

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Novel Research Frontiers on the Management of FCS

HCPLive

Panelists discuss how various new and developing approaches for treating familial chylomicronemia syndrome are emerging, and emphasize the importance for clinicians to integrate these advancements into practice while staying current with ongoing research and evolving treatment strategies.

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Meta-Analysis of Semaglutide and BP

American College of Cardiology

Does use of semaglutide decrease blood pressure (BP) and, if so, does it decrease it more in people with higher starting BPs? Also, can the BP drop be attributed solely to the weight loss?

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IL-17, IL-23 Inhibitors Show Fastest Times to Meaningful Clinical Response for Psoriasis

HCPLive

These data resulted from comparisons of the time to onset of action among various available systemic medications for those with plaque psoriasis.

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ACC CardiaCast: Pulse Check: What’s new in AFib for the Pharmacists CV Team Professional?

American College of Cardiology

Special Edition: PharmD Appreciation: “PulseCheck” is a series within CardiaCast that is designed for Cardiovascular (CV) Team members who are new, or new to cardiology, offering practical team-based solutions to the everyday challenges.

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Current IBS, Functional Dyspepsia Clinical Criteria Neglect Patient Experiences

HCPLive

In focus groups, patients indicated symptom bothersomeness and life interference should be included in clinical evaluation for disorders of gut-brain interaction.

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Cardiac Arrhythmias and Autonomic Dysfunction Associated With COVID-19: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Cardiac arrhythmias are commonly noted in patients during infections with and recovery from COVID-19. Arrhythmic manifestations span the spectrum of innocuous and benign to life-threatening and deadly. Various pathophysiological mechanisms have been proposed. Debate continues on the impact of incident and exacerbated arrhythmias on the acute and chronic (recovery) phase of the illness.

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Phase 3 Data Supports the Long-Term Safety of STS101 for Acute Treatment of Migraine

HCPLive

Phase 3 data found 66.5% of people with migraine attacks treated with STS101 had headache pain relief two hours after the dose.

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Short-Term DAPT After DES in Patients With ACS

American College of Cardiology

What is the efficacy and safety of different durations of dual antiplatelet therapy (DAPT) strategies in patients with acute coronary syndromes (ACS) using a Bayesian network meta-analysis?

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Linaclotide Improves Symptoms, Quality of Life After Non-Response to Magnesium Oxide

HCPLive

Linaclotide was safe and effective for patients with chronic constipation and IBS with constipation who switched after non-response to magnesium oxide.

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Catheter-Based Renal Denervation in HTN: Key Points

American College of Cardiology

The following are key points to remember from a systematic review and meta-analysis on the effects of catheter-based renal denervation in patients with hypertension (HTN).

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Stephanie Christenson, MD: An "Exciting" New Era in COPD Management

HCPLive

Stephanie Christenson, MD, discusses the impact of recent regulatory approvals and pipeline movement for chronic obstructive pulmonary disease.

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Case Report: Laboratory detection of a thrombotic tendency in a family with hypodysfibrinogenemia and a novel FGG mutation

Frontiers in Cardiovascular Medicine

IntroductionHypodysfibrinogenemia is a rare congenital fibrinogen disorder (CFD) which may induce thrombotic and bleeding events. Therefore, patient management needs careful evaluation. Routine coagulation tests are inadequate to predict the clinical phenotype.Clinical findingsA 60-year-old woman with both bleeding and thrombotic complications and her two daughters were referred to our center for genotypic and phenotypic analysis of a CFD.DiagnosisConventional laboratory results led to the diagn

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Guselkumab Yields Durable Improvements in Psoriatic Arthritis

HCPLive

Of patients randomized to guselkumab Q8W, 93% to 99% maintained minimally clinically important improvements in joint disease through 1 year.

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Investigating the causal relationship between human blood metabolites and pulmonary hypertension: a two-sample Mendelian randomization study

Frontiers in Cardiovascular Medicine

BackgroundSeveral recent investigations have posited that distinct metabolites in the bloodstream may be correlated with the pathogenesis of Pulmonary Hypertension (PH). Nonetheless, the interrelationship between the pathogenesis of PH and metabolite fluctuations remains incompletely elucidated, and findings may differ across studies.MethodsIn the extant research, data from 486 metabolite-and PH-related genetic variants in human subjects were procured based on Genome-Wide Association Studies (GW

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Cognitive Dysfunction Common in Patients with Sickle Cell Anemia

HCPLive

A systematic review found cognitive impairment a defining characteristic of SCA, with a notable impact on individuals of all ages.

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Endovascular Management of Acute Stroke: Key Points

American College of Cardiology

The following are key points to remember from a review on endovascular management of acute stroke.

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The Potential Role of Dupilumab in COPD Management, with Antonio Anzueto, MD

HCPLive

Antonio Anzueto, MD, discusses how dupilumab fits into treatment algorithms for patients with uncontrolled COPD.

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Webinar on Changing Data Demands of Next-Gen Healthcare to Take Place Next Month

DAIC

tim.hodson Mon, 10/14/2024 - 16:20 On Nov. 13, 2024, HIMSS will be presenting a webinar on "Addressing the Changing Data Demands of Next-Gen Healthcare." The webinar will take place at 1 p.m. Central time. The delivery of next-generation patient care relies upon seamless access to comprehensive and relevant patient data. However, the proliferation of patient data silos across multiple hosted environments can present significant integration challenges.

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Anemia Notably Impacts Heart Failure Prognosis, Study Finds

HCPLive

Anemia could be a reliable sign of all-cause mortality in patients with heart failure.

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Protein Drivers of Heart Attack Risk Disproportionately Affect Women

Med Page Today

(MedPage Today) -- Sex-specific molecules contributing to one's risk of myocardial infarction (MI) were identified by researchers using proteomic profiling. Based on targeted cardio-metabolic proteomics on two large-scale biobanks, there were.

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Sex-specific differences in the association between triglyceride glucose index and carotid plaque in a cardiovascular high-risk population: a cross-sectional study based on a Chinese community-dwelling population

Frontiers in Cardiovascular Medicine

BackgroundTo date, numerous studies have investigated the relationship between the triglyceride glucose (TyG) index and carotid plaques, but the impact of gender on this relationship has not been explored. Therefore, this study aims to investigate gender-specific differences in the relationship between the TyG index and carotid plaques in a high cardiovascular risk population in China.MethodsThis cross-sectional study's data were derived from a longitudinal pilot study involving 1,085 high-risk

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