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Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute Myocardial Infarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardial infarction (MI) has changed over time. Patients recruited to these trials had left ventricular ejection fraction (LVEF) <40% following acute MI.
(MedPage Today) -- A three-step process underscores new clinical practice guidelines for primary and specialty care clinicians to evaluate patients who may have cognitive impairment or dementia due to Alzheimer's or a related disease. In broad.
Journal of the American Heart Association, Ahead of Print. BackgroundInfective endocarditis (IE) is still a fatal disease, and given its rarity, ongoing updates to patient characteristics and outcomes of IE are essential for providing precision diagnoses and effective treatments. This study sought to examine temporal trends in the clinical characteristics and inhospital occurrence of adverse outcomes of IE.Methods and ResultsUsing the Japan nationwide administrative database, we identified patie
The U.S. government's premier research body has made an important discovery that could help create new drugs to lower "bad" cholesterol, and hopefully prevent heart attacks and stroke.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
(MedPage Today) -- MedPage Today's enterprise and investigative team covers a lot of ground. We jump in when there's breaking news in healthcare. We write second-day stories on the implications of that news. We craft compelling feature stories.
Notwithstanding many insightful observations, the electrocardiogram (ECG) arguably ignited the big bang in our understanding of cardiac arrhythmias. Using ECG recording and deductive reasoning, our teachers and predecessors classified the bradycardias and tachycardias and proposed many mechanisms, subsequently proven to be correct. The development of electrophysiology (EP) studies through intravascular catheters provided the leap to verifying mechanisms, setting the stage for interventions.
Each child had already undergone at least three open-heart surgeries. They'd endured countless hours in doctors' offices and hospitals after being born with a serious heart condition.
Each child had already undergone at least three open-heart surgeries. They'd endured countless hours in doctors' offices and hospitals after being born with a serious heart condition.
Based on a blend of number of listens, views, feedback from listeners, website traffic and personal faves, EM Cases Top 10 Best of 2024 podcasts, videos and blog posts. The post EM Cases Top 10 Best of 2024 appeared first on Emergency Medicine Cases.
Cell therapy, particularly CAR-T, is expanding into autoimmune diseases like lupus and multiple sclerosis. While promising, safety, efficacy, and broad applicability remain uncertain.
(MedPage Today) -- Undersized donor hearts were indeed associated with more post-transplantation mortality -- but only among complex transplant recipients, a Nashville center found. (Annals of Thoracic Surgery) In Japan, the incidence of infective.
Lungcast reflects on this year in pulmonology, looking back at such topics ranging from the American Lung Association State of the Air report to artificial intelligence in lung imaging.
Year 1 of the new editorship (year 21 for the Journal) passed in the blink of an eye. I am happy to report to our Editorial Board and readers that this first year was good in all important measurable parameters or journal metrics.
Publication date: Available online 30 December 2024 Source: The American Journal of Cardiology Author(s): Mohamad B. Moumneh, Mohammed A. Quader, Nicholas R. Teman, Daniel Tang, Liam Ryan, Raymond J. Strobel, Mark Joseph, Michael Mazzeffi, Zachary M. Gertz, Michael C. Kontos, Ramesh Singh, Alan Spier, Eric Sarin, Abdulla A.
Written by Pendell Meyers A woman in her 70s with known prior coronary artery disease experienced acute chest pain and shortness of breath. The chest pain was described as severe pressure radiating to both shoulders. Vital signs were within normal limits. She presented to the Emergency Department at around 3.5 hours since onset. She had taken aspirin at home.
Underlying normal cardiac rhythm is a network of transcriptional programs that ensures normal impulse initiation and impulse propagation. We highlight work that shows how alterations in individual transcriptional networks can lead to increased arrhythmia susceptibility, cardiomyopathy, and congenital heart defects. Lastly, we focus on a study that leverages transcription factor biology to therapeutically modulate heart rhythm.
Hypertension, Ahead of Print. Elevated blood pressure (BP) remains the leading cause of mortality globally, and efforts to control it have been disappointing. Meta-analyses of antihypertensive randomized controlled trials reveal a near-exact reversal of the BP-related risks identified in cohort studies. For an observed increase in cardiovascular disease risk of 12.5%, 25%, 50%, and 75% with a 5, 10, 20, or 40 mm Hg higher level of BP, respectively, the corresponding BP reductions in antihyperten
If you have been to an airport lately, you likely will agree that people are moving around the globe in ever-increasing numbers. UN Tourism reported that 790 million people traveled internationally in the first 7 months of 2024, an increase of 11% over 2023. Forbes predicts that the global business market will surpass US$1.5 trillion in 2024. These numbers are nearing the prepandemic records and are a clear indictor of the interest in being internationally connected.
Since the first report 30 years ago of inherited fetal long QT syndrome (LQTS) presenting as mild fetal bradycardia, more than 265 prenatal cases of LQTS have been reported.1 The importance of prenatal recognition cannot be overestimated because of the significant risk for stillbirth or premature delivery and the value of primary prevention for the infant proband and LQTS-positive family members.
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