Mon.Oct 07, 2024

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Arm position effect on blood pressure readings: 5 things to know

Becker's Hospital Review - Cardiology

Insufficient arm support can lead to an overestimated blood pressure reading of almost 7mmHG and a potential misdiagnosis of hypertension, according to a study published Oct. 7 in JAMA Internal Medicine.

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Commonly used arm positions can substantially overestimate blood pressure readings

Science Daily - Heart Disease

Researchers conclude that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.

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Study Supports News of Benzene in Benzoyl Peroxide Acne Products

HCPLive

These new data provide additional evidence for a range of benzene concentrations detected by in over-the-counter drug products with BPO maintained at room temperature.

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SGLT2 Inhibitors Tied to Better Outcomes in Pulmonary Arterial Hypertension

Med Page Today

(MedPage Today) -- BOSTON -- Sodium-glucose cotransporter-2 (SGLT2) inhibitors were linked to long-term reductions in mortality risk among patients with pulmonary arterial hypertension (PAH), according to an observational cohort study. At 1.

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Anemia May Worsen Prognosis of Primary Care Patients with Heart Failure

HCPLive

Anemia is frequently observed in primary care patients with HF and is linked to worse prognosis and comorbidities, including cancer.

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Common consumer product chemicals now tied to cardiac electrical changes

Science Daily - Heart Disease

Some environmental phenols are known to have cardiac toxicities. Now, a new study is revealing their adverse impact on the heart's electrical properties.

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Iron Therapy Underutilized in Post-Kidney Transplant Anemia, Study Finds

HCPLive

This retrospective analysis examined the current management of early and late anemia in a representative sample of the kidney transplant population in Spain.

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Nephrology Month in Review: September 2024

HCPLive

This September 2024 month in review spotlights our top coverage of recent nephrology pipeline updates, guidelines, and research.

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Share Your Expertise: Submit and Discuss Your Most Challenging Interventional Cardiology Cases at Our Upcoming Symposium

ADN Center of Excellence

Interventional cardiology has dramatically evolved over the past decades, introducing advanced techniques and tools that have revolutionized the treatment of coronary artery disease, valvular disorders, and structural heart diseases. However, with such advancements come new challenges complex cases that push the boundaries of conventional practice. For many seasoned interventional cardiologists, managing complications is not only a test of their technical prowess but also a testament to their ab

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Comparing Treatment Options for Psoriatic Arthritis with Philip Mease, MD

HCPLive

Mease discussed the importance of comparator studies in a growing treatment landscape for PsA.

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Right thoracotomy with central cannulation for valve surgery: 10 years of experience

Journal of Cardiothoracic Surgery

The aim of this study is to report the early outcomes of valvular heart surgeries performed via the right thoracotomy approach. While thoracotomy with femoro-femoral bypass is an established method for minimal.

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FDA Approves 3 Tubes of Aminolevulinic Acid Hydrochloride for Actinic Keratosis

HCPLive

The decision by the FDA follows an announcement by Biofrontera that there were no safety issues found following the submission of the medication’s supplemental New Drug Application.

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Propensity score-based comparison of high-risk coronary artery bypass grafting vs. left ventricular assist device implantation in patients with coronary artery disease and advanced heart failure

Frontiers in Cardiovascular Medicine

ObjectivesRevascularization in patients with severely reduced left ventricular function and coronary artery disease (CAD) is associated with a high perioperative risk. In this setting, implantation of a durable left ventricular assist device (LVAD) might be an alternative.MethodsWe retrospectively compared the outcomes of adult patients with CAD and a left ventricular ejection fraction (LVEF) ≤ 25% who underwent coronary artery bypass grafting (CABG) vs.

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The APAC Recap: RhAPP 5th Annual National Conference, with Laura Ross, PA-C

HCPLive

APAC President Laura Ross, PA-C, shares insights from the RhAPP conference, discussing autoimmune disease, cardiovascular risks, and the importance of interdisciplinary care.

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Causal association between common rheumatic diseases and arrhythmia: a Mendelian randomization study

Frontiers in Cardiovascular Medicine

BackgroundObservational studies have suggested a link between rheumatic diseases and arrhythmias. However, these studies have been limited by confounding factors and reverse causality, leaving the causal relationship between rheumatic diseases and arrhythmias uncertain. This study addresses this inquiry using genetic evidence.MethodsSelected single nucleotide polymorphisms (SNPs) from genome-wide association study (GWAS) data were employed as instrumental variables.

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Youth Reluctant to Seek Mental Health Care Post-Black-Box Warning on Antidepressants

HCPLive

A recent study shows the FDA's black-box warnings on antidepressants have led to decreased usage among youth, with an increase in suicide attempts and deaths observed.

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The association of perioperative serum uric acid variation with in-hospital adverse outcomes in coronary artery bypass grafting patients

Frontiers in Cardiovascular Medicine

BackgroundPrevious studies proposed the predictive value of baseline serum uric acid (SUA) in the prognosis of coronary artery bypass grafting (CABG) patients. The association of perioperative SUA variation with in-hospital adverse outcomes in CABG patients is unknown.MethodsA total of 2,453 patients were included in the study and were divided into four groups (G1–G4) according to perioperative SUA variation (ΔSUA) (G1, ΔSUA ≤ −90 μmol/L; G2, −90 μmol/L < ΔSUA < 0; G3, 0 ≤ ΔSUA < 30 μmol/L; G4,

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Why heart patients have trouble sticking to a healthy diet, and three things that help them eat better

Medical Xpress - Cardiology

Cardiovascular disease remains a leading cause of death worldwide, and managing it effectively requires more than just medical intervention: what you eat plays a crucial role in your heart's health.

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Factors related to cardiac rupture after acute myocardial infarction

Frontiers in Cardiovascular Medicine

BackgroundCardiac rupture (CR) after acute myocardial infarction (AMI) is a fatal mechanical complication. The early identification of factors related to CR in high-risk cases may reduce mortality. The purpose of our study was to discover relevant risk factors for CR after AMI and in-hospital mortality from CR.MethodsIn this study, we enrolled 1,699 AMI cases from October 2013 to May 2020.

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Share Your Expertise: Submit and Discuss Your Most Challenging Interventional Cardiology Cases at Our Upcoming Symposium

ADN Center of Excellence

Interventional cardiology has dramatically evolved over the past decades, introducing advanced techniques and tools that have revolutionized the treatment of coronary artery disease, valvular disorders, and structural heart diseases. However, with such advancements come new challenges complex cases that push the boundaries of conventional practice. For many seasoned interventional cardiologists, managing complications is not only a test of their technical prowess but also a testament to their ab

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Examining the causal association between moderate alcohol consumption and cardiovascular risk factors in the Taiwan Biobank: a Mendelian randomization analysis

Frontiers in Cardiovascular Medicine

BackgroundThe Mendelian randomization approach uses genetic variants as instrumental variables to study the causal association between the risk factors and health outcomes of interest. We aimed to examine the relation between alcohol consumption and cardiovascular risk factors using two genetic variants as instrumental variables: alcohol dehydrogenase 1B (ADH1B) rs1229984 and aldehyde dehydrogenase 2 (ALDH2) rs671.MethodsUsing data collected in the Taiwan Biobank—an ongoing, prospective, populat

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Factors associated with acute kidney injury after on-pump coronary artery bypass grafting

Journal of Cardiothoracic Surgery

Acute kidney injury (AKI) frequently occurs as a complication of cardiac surgery and cardiopulmonary bypass (CPB). Its prevalence and severity are determined by various preoperative and intraoperative factors.

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Plasma proteomics and carotid intima-media thickness in the UK biobank cohort

Frontiers in Cardiovascular Medicine

Background and aimsUltrasound derived carotid intima-media thickness (cIMT) is valuable for cardiovascular risk stratification. We assessed the relative importance of traditional atherosclerosis risk factors and plasma proteins in predicting cIMT measured nearly a decade later.MethodWe examined 6,136 UK Biobank participants with 1,461 proteins profiled using the proximity extension assay applied to their baseline blood draw who subsequently underwent a cIMT measurement.

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A rare case of IgG4-related aortitis in the thoracic aorta mimicking an intramural hematoma: navigating the diagnostic labyrinth

Journal of Cardiothoracic Surgery

A 54-year-old female presented with recurrent abdominal pain and new onset chest pain. Chest computed-tomography angiogram detected a thoracic aortic aneurysm with suspected Type A intramural hematoma (IMH) versu.

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Sigmoid ventricular septum treated with endocardial ablation to improve left ventricular outflow: cases report

Frontiers in Cardiovascular Medicine

BackgroundSigmoid Ventricular Septum (SVS) is a type of hypertrophic cardiomyopathy characterized by a reduced angle between the basal interventricular septum and the ascending aorta, and SVS can lead to dynamic Left Ventricular Outflow Tract obstruction (LVOTO) during hypercontractile states. Patients experiencing LVOTO may manifest symptoms such as angina, syncope, etc.

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Treatment Expectations and Patient Conversations in Atopic Dermatitis

HCPLive

Medical experts discuss the importance of setting treatment expectations and maintaining dialogue with patients about targets and explain how to decide on a new treatment when switching.

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Impact of systemic lupus erythematosus on cardiovascular morphologic and functional phenotypes: a Mendelian randomization analysis

Frontiers in Cardiovascular Medicine

BackgroundPrevious studies have established a correlation between systemic lupus erythematosus (SLE) and cardiovascular health, but the potential causal effects of SLE on heart function and structure remain poorly understood. Cardiovascular magnetic resonance imaging (CMR), a novel non-invasive technique, provides a unique assessment of cardiovascular structure and function, making it an essential tool for evaluating the risk of heart disease.

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Switching from Biologics to JAK Inhibitors in Atopic Dermatitis: Clinical Data

HCPLive

Medical experts discuss disease control with abrocitinib or upadacitinib in patients previously taking dupilumab and explain the circumstances under which they would switch a patient to a JAK inhibitor.

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Predictive value of geriatric nutritional risk index in cardiac and cerebrovascular events after endovascular aortic aneurysm repair

Frontiers in Cardiovascular Medicine

ObjectiveTo evaluate the effect of malnutrition assessed by the Geriatric Nutritional Risk Index (GNRI) on major adverse cardiac and cerebrovascular events (MACCE) in the elderly patients after endovascular aortic aneurysm repair (EVAR).Materials and methodsThis was a retrospective cohort study of elderly patients who underwent EVAR in a tertiary hospital.

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SHASTA-2 Trial: Plozasiran’s Efficacy in Reducing Triglycerides and APOC3

HCPLive

Panelists discuss how the SHASTA-2 study evaluated the efficacy and safety of plozasiran in reducing triglyceride levels and APOC3 in familial chylomicronemia syndrome, comparing outcomes with the placebo group and assessing implications for treating severe hypertriglyceridemia and preventing pancreatitis.

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Association between myocardial layer-specific strain and high 10-year risk of atherosclerotic cardiovascular disease in hypertension—findings from the China-PAR project study

Frontiers in Cardiovascular Medicine

ObjectivesMyocardial layer-specific strain is a sensitive tool for detecting myocardial dysfunction. The objective of this study was to assess changes in the left ventricle (LV) function using myocardial layer-specific strain and its association with 10-year atherosclerotic cardiovascular disease risk (10Y-ASCVDR) in individuals with hypertension (HP).MethodsThe parameters of LV structure, including layer-specific global longitudinal strain (GLSww, GLSendo, GLSmid, GLSepi) and layer-specific glo

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Reflections on Plozasiran Trial Data and Future Potential

HCPLive

Panelists discuss how various new and developing approaches for treating familial chylomicronemia syndrome are emerging, and emphasize the importance for clinicians to integrate these advancements into practice while staying current with ongoing research and evolving treatment strategies.

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Causal relationship between immunophenotypes and mitral valve prolapse: a bidirectional Mendelian randomization study

Frontiers in Cardiovascular Medicine

BackgroundEmerging evidence indicates a significant link between various immune cell types and the development of heart valve disorders. Mitral valve prolapse (MVP) is a common condition that can lead to heart failure, arrhythmias, and even sudden death. Currently, the role of immune cells in MVP is not well understood. Thus, this study aimed to explore the causal relationship between immunophenotypes and the risk of MVP.MethodsThis study conducted a two-sample Mendelian randomization (MR) analy

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Clinical Quiz: MAESTRO-NASH Trial Procedures for Resmetirom in MASH

HCPLive

Test your knowledge of the phase 3 MAESTRO-NASH trial supporting resmetirom (Rezdiffra)’s FDA accelerated approval for MASH with this quiz.

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Complicated atrial myxoma with coro-cameral fistula arising from its feeding branch: a case report

Frontiers in Cardiovascular Medicine

A 56-year-old man with a 5-year history of paroxysmal palpitations, which have worsened over the past year, was diagnosed with atrial fibrillation. During evaluation, transesophageal echocardiography revealed a left atrium (LA) tumoral mass attached to the atrial septal fossa ovale, with intra-tumoral blood flow and blood stream draining from the mass.

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ACC CardiaCast: Pulse Check: What’s New in Heart Failure for the Pharmacist CV Team Professional?

American College of Cardiology

In this episode, Andrea Price, MS, AACC hosts Jessie Dunne, PharmD, BCCP, BCPC and Orly Vardeny, PharmD, MS, FAHA, FHFSA to discuss the most recent heart failure guidelines, expert consensus publication, and what these documents mean to a pharmacist working on a heart failure care team.

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A multi-site mixed-method evaluation of ‘Cardiac College for Women’ implementation: perspectives of cardiac rehabilitation patients and providers

Frontiers in Cardiovascular Medicine

A Cardiac College for Women curriculum was developed to address the dearth of women-focused cardiac rehabilitation (CR) education. This study investigated: (1) patient utilization of the education; (2) acceptability and applicability of the education; as well as (3) patient and CR providers’ experiences implementing it. This was a multi-site, mixed-methods study.