Sun.May 19, 2024

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Implications of HBV DNA Integration on Care in 2024

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on how advancing understanding of HBV DNA integration is influencing care in 2024.

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Hormone replacement therapy may improve pulmonary hypertension and right ventricular function

Medical Xpress - Cardiology

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego. Pulmonary hypertension (PH) is a type of pulmonary vascular disease—disease that affects blood vessels along the route between the heart and lungs.

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Exploring Diet’s Role in Managing Ulcerative Colitis, with Oriana Damas, MD

HCPLive

Damas explains what inspired her research about the impact of a low-calorie plant-based diet on clinical response to medication in patients with ulcerative colitis.

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Cardiac care: more good news for young, healthy white men

Heart Sisters

This international Commission aims to address the known disparities in cardiovascular care which vary depending on your age, your skin colour, your mental health and whether you're a man or a woman.

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Improving Hepatitis B Screening and Vaccination in 2024

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on the need to improve HBV screening and vaccination.

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Lipid-based insulin-resistance markers predict cardiovascular events in metabolic dysfunction associated steatotic liver disease

Cardiovascular Diabetology

Insulin resistance (IR) is the cornerstone of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), pathophysiologically being the key link between MASLD, metabolic disorders, and cardiovascular (C.

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Therapeutic Pipeline Updates in Hepatitis B Virus for 2024

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on updates in the therapeutic pipeline.

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The Rising Rate of Heat-Related Illness, with Janelle Bludhorn, PA-C

HCPLive

With incidence climbing amid climate change, an emergency medicine doctor has advice on prevention of cardiovascular and dermatologic effects.

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Mediterranean Diet After Afib Ablation: Maybe?

Med Page Today

(MedPage Today) -- BOSTON -- An olive oil-enhanced Mediterranean diet didn't help prevent atrial fibrillation (Afib, or AF) recurrence after ablation in the PREDIMAR randomized trial, although there was a signal for benefit in paroxysmal cases.

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GLP-1 Agonist Safety Risks and Obesity Stigma with Kevin Peterson, MD, MPH

HCPLive

Peterson reviews the gastric and hormonal events linked to drugs like tirzepatide, before considering whether incretin therapies will help to finally embrace obesity as the medical condition it is.

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An explainable machine learning approach using contemporary UNOS data to identify patients who fail to bridge to heart transplantation

Frontiers in Cardiovascular Medicine

BackgroundThe use of Intra-aortic Balloon Pump (IABP) and Impella devices as a bridge to heart transplantation (HTx) has increased significantly in recent times. This study aimed to create and validate an explainable machine learning (ML) model that can predict the failure of status two listings and identify the clinical features that significantly impact this outcome.MethodsWe used the UNOS registry database to identify HTx candidates listed as UNOS Status 2 between 2018 and 2022 and supported

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Responders to PCI for Angina Relief Identified by Chest Pain Type

Med Page Today

(MedPage Today) -- PARIS -- Whether a person had chest pains resolved by angioplasty hinged on the nature, not the severity, of their presenting symptoms, an ORBITA-2 analysis showed. Investigators found two groups more likely to benefit from.

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What Should the American Academy of Physician Associates Focus on in 2025?

HCPLive

During AAPA 2024, a group of session presenters provide recommendations for the next year's agenda based on trends and development.

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Bile acid receptor protects against diabetic cardiomyopathy

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 20 May 2024; doi:10.1038/s41569-024-01040-y Activation of the bile acid receptor TGR5 inhibits CD36-mediated fatty acid uptake in cardiomyocytes and protects against cardiac lipotoxicity and the development of diabetic cardiomyopathy in mice, according to a new study.

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Role of Advocacy, Patient Voice in Hepatitis B

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on the role of advocacy and patient voice in HBV management.

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TMVR after TA-TAVR: a re-redo surgery—case report

Frontiers in Cardiovascular Medicine

IntroductionTranscatheter mitral valve replacement (TMVR) is a valuable treatment option in patients with severe mitral regurgitation. Prior transapical transcatheter aortic valve replacement (TA-TAVR) may complicate the procedure and is therefore considered a relative contraindication. In this case report, the authors describe the successful TMVR as a tertiary cardiac surgery and transapical redo procedure.Case SummaryAn 83-year-old male patient, suffering from dyspnoea and angina, was diagnose

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Role of Advocacy, Support in Hepatitis B Virus

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on the role of advocacy and patient voice in HBV management.

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Transcatheter PFO closure for cryptogenic stroke: current approaches and future considerations

Frontiers in Cardiovascular Medicine

Patent Foramen Ovale (PFO) is a common congenital atrial septal defect present in 20%–35% of the general population. Although generally considered a benign anatomic variant, a PFO may facilitate passage of a thrombus from the venous to arterial circulation, thereby resulting in cryptogenic stroke or systemic embolization. A PFO is detected in nearly one half of patients presenting with cryptogenic stroke and often considered the most likely etiology when other causes have been excluded.

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Advances in Pathophysiology of Hepatitis B Virus for 2024

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on advances in the pathophysiology of hepatitis b virus for 2024.

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Retrosternal hematoma causing torsade de pointes after coronary artery bypass graft surgery; a case report

Frontiers in Cardiovascular Medicine

Myocardial infarction is among the top causes of mortality worldwide. Survivors may also experience several complications. Infarct-related torsade de pointes (TdP) is an uncommon complication. In the context of myocardial infarction, coronary artery bypass graft (CABG) surgery is the prevalent therapeutic modality associated with several early and late complications.

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Dupilumab Benefits Esophageal Feature Scores in Children with EoE

HCPLive

At week 52 of the Phase 3 EoE KIDS trial, higher exposure dupilumab significantly improved the endoscopic reference score in children with EoE.

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CLINICAL PERFORMANCE AND PERSISTENCE ON DUAL PATHWAY INHIBITION WITH RIVAROXABAN AND ASPIRIN IN REAL-WORLD SETTING.

Journal of Cardiovascular Pharmacology

The dual pathway inhibition (DPI) with low dose rivaroxaban and aspirin in patients with stable atherosclerotic vascular disease reduced the occurrence of cardiovascular (CV) events, with no significant increase of intracranial or other critical organ bleedings. Our observational study aimed to describe the clinical performance, adherence and persistence of DPI therapy among a real-world setting of patients with an established diagnosis of coronary artery (CAD) and/or peripheral artery disease (

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Study Assesses Predictive Markers of Resmetirom Histological Response in MAESTRO-NASH

HCPLive

Results presented at DDW detail the association between ALT, Fibroscan CAP, Fibroscan VCTE, and histological response to resmetirom in patients enrolled in MAESTRO-NASH.

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Diversity in Atrial Fibrillation Trials: Assessing the Role of Language Proficiency as a Recruitment Barrier

HeartRhythm

In the United States (US), 67.8 million people (21%) do not claim English as their primary language, up from 23.1 million in 1980.1 Limited English proficiency has been associated with poorer health outcomes due to barriers in communication.2,3 As most US clinical trials are conducted in English, many potential clinical trial participants may be excluded because of their language proficiency.

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Discussing Unmet Needs in Hepatitis B for 2024

HCPLive

In this segment of our 6-part discussion on updates and unmet needs within the management of hepatitis B virus focuses on the most pressing unmet needs in HBV for 2024.

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Comparative Effectiveness of Intravascular Ultrasound versus Angiography in Abdominal and Thoracic Endovascular Aortic Repair: Systematic Review and Meta-Analysis

The American Journal of Cardiology

Publication date: Available online 18 May 2024 Source: The American Journal of Cardiology Author(s): Tomonari Shimoda, Mario D'Oria, Toshiki Kuno, Patrick Heindel, Sandro Lepidi, Mohamad A. Hussain, Hisato Takagi, Eric A.

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Wei Zhang, MD, PhD: Recognizing Disparities in Hepatocellular Carcinoma Diagnosis, Care

HCPLive

Zhang explains disparities in HCC care and the negative impact on long-term outcomes, also addressing potential considerations for vulnerable patient populations.

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Assessment Of Coronary Stenoses For Percutaneous Coronary Intervention: A Systematic Review And Network Meta-Analysis Of Randomized Trials

The American Journal of Cardiology

Publication date: Available online 18 May 2024 Source: The American Journal of Cardiology Author(s): Marc-André d'Entremont, Denise Tiong, Behnam Sadeghirad, Brian P. McGrath, Giacomo Maria Cioffi, Turki Al Garni, Zain M. Cheema, Jamie Layland, Pruthvi C. Revaiah, Patrick W. Serruys, Gregg W. Stone, Sanjit S.

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“We’re at a Complete Disconnect”: Marla Dubinsky, MD, on Bowel Urgency in IBD

HCPLive

Dubinsky explains the disconnect between patients with Crohn disease and health care providers regarding the impact of and importance of addressing bowel urgency.

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Brachiocephalic Artery Access for Transcatheter Aortic Valve Replacement

All About Cardiovascular System and Disorders

Transcatheter aortic valve replacement (TAVR) is increasing in popularity for symptomatic severe aortic stenosis. Transfemoral arterial route is the most commonly used approach for TAVR, also known as TAVI or transcatheter aortic valve implantation. It does not involve open heart surgery which is otherwise needed for surgical aortic valve replacement.

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Digital Health Monitoring Platforms Feasible for IBD Management

HCPLive

The MyGut digital health monitoring platform proves feasible and impactful during integration into inflammatory bowel disease care.

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Leveraging Human Tissue for Discovery in Heart Transplantation

Circulation

Circulation, Volume 149, Issue 21 , Page 1667-1669, May 21, 2024.

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EoE KIDS: Higher Exposure Dupilumab Improves Histologic, Endoscopic Outcomes

HCPLive

Higher exposure dupilumab significantly improved histologic and endoscopic outcomes in children with EoE aged 1 to <12 years.

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Correction to: Organ Donation After Out-of-Hospital Cardiac Arrest: A Scientific Statement From the International Liaison Committee on Resuscitation

Circulation

Circulation, Volume 149, Issue 21 , Page e1217-e1217, May 21, 2024.

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Microbiota-Focused Dietary Modulation May Improve MAFLD Management

HCPLive

Microbiota differences between individuals with and without MAFLD were associated with dietary intake and clinical outcomes.

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Intracardiac Echo Guided Left Atrial Appendage Closure: Quo Vadis?

The American Journal of Cardiology

Publication date: Available online 19 May 2024 Source: The American Journal of Cardiology Author(s): N.A.

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Breath Analysis Can Aid Clinical Characterization of Microbiome Metabolism

HCPLive

Findings were presented at DDW and highlight the feasibility of breath analysis for microbiome metabolic characterization in the digestive system.

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