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Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.
By Smith with comments from our electrophysiologist, Rehan Karim. (And of course Ken's comments at the bottom) An elderly obese woman with cardiomyopathy, Left bundle branch block, and chronic hypercapnea presented hypoxic with altered mental status. She was intubated. Bedside cardiac ultrasound showed moderately decreased LV function. CT of the chest showed no pulmonary embolism but bibasilar infiltrates.
What is inside the Heart Health Formula? A step-step guide to: - Understanding Heart Disease. - Defining Heart Disease Risk. - Reducing Heart Disease Risk. When I set out on my journey over a decade ago to put together a system to do this comprehensively, it did not exist in a way that I found useful. So, I created a system myself. The Heart Health Formula is made up of 3 main modules.
COVID-19 is a respiratory disease primarily affecting the lungs. However, the SARS-CoV-2 virus that causes COVID-19 surprised doctors and scientists by causing an unusually large percentage of patients to experience vascular complicationsissues related to blood flow, such as blood clots, heart attacks, and strokes.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Although the oral navacaprant 80 mg failed to bring statistically significant improvements in depression symptoms, the study showed females respond better than males.
There's no question that exercise is good for the heart. Regular exercise lowers blood pressure and cholesterol and reduces the chances of having a heart attack or stroke.
Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement.
Despite the promising results of both MitraClip and PASCAL systems for the treatment of mitral regurgitation (MR), there is limited data on the comparison of both systems regarding their safety and efficacy. W.
Weight loss tops many folks' list of New Year's resolutions, and lots of people are turning to cutting-edge weight-loss drugs like Ozempic to help them drop excess pounds.
Some heart failure patients with artificial hearts have been able to regenerate heart muscle, potentially paving the way for future heart failure treatment options, according to a study published Nov. 21 in Circulation.
Patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis cardiovascular disease (CVD) compared to those with early-stage cancer at diagnosis.
A recent study identified the prevalence of asymptomatic pulmonary involvement in patients with newly diagnosed RA or PsA, highlighting the need to reevaluate screening protocols.
Carinal resection and reconstruction are complex surgical procedures often necessitated by tumors or other pathologies involving the tracheobronchial junction. Traditional approaches to these surgeries are hig.
In this analysis, baseline peanut sIgE was shown to be a stronger predictor of remission after peanut OIT than age at the beginning of immunotherapy treatment.
Pseudoaneurysm after coarctation of the aorta (CoA) repair is a rare but severe complication. Contributing factors may include infection, hypertension, aortic wall weakness, and turbulent blood flow at the rep.
Event 2025 STS/EACTS/LACES Latin America Cardiovascular Surgery Conference gmckinney Thu, 01/02/2025 - 11:11 Event dates Dec 46, 2025 Location Lima, Peru A world-class, international event that will explore the latest developments and best practices in coronary artery disease, congenital heart disease, thoracic aortic disease, atrial fibrillation, and the surgical management of heart failure.
Event 2025 Advances in Quality & Outcomes: A Data Managers Meeting gmckinney Thu, 01/02/2025 - 11:08 Event dates Oct 13, 2025 Location San Antonio, TX AQO 2025 will offer a unique opportunity to explore techniques for optimizing data collection using case scenarios and driving quality improvement. Head for San Antonio this October to attend the premier gathering of STS National Database professionals as they share valuable research and important clinical findings with hundreds of peers.
Potassium nitrate increased blood nitric oxide metabolites but showed no improvement in exercise tolerance or quality of life in a population with HFpEF.
Event 2025 STS Coronary Conference gmckinney Thu, 01/02/2025 - 10:57 Event dates Jun 1214, 2025 Location Chicago, IL The 2025 STS Coronary Conference is an innovative international event taking place June 12-14, in Chicago. Abstract submissions will begin soon! Add your name to the interest list if you would like to be notified when abstracts and registration open.
Event 2025 STS Workshop on Robotic Thoracic Surgery gmckinney Thu, 01/02/2025 - 10:53 Event dates May 1516, 2025 Location Norcross, GA Save the date! The popular STS Workshop on Robotic Thoracic Surgery will return to the Atlanta area in spring 2025. Details will be available soon! Add your name to the interest list to be among the first informed when registration opens.
Pulmonary embolism (PE), a form of venous thromboembolism, is a frequently observed complication in malignancies, with a notably high incidence in individuals with lung cancer. The presence of PE markedly redu.
Right ventricular myocardial work (RVMW) assessed by transthoracic echocardiography allows to study the right ventricular (RV) function using RV pressure-strain loops. The assessment of these novel indexes of.
Imagine putting your socks on one morning and noticing your big toe, which has been painful for a few weeks, has started turning black. A trip to your doctor ends in being referred urgently to a specialist. They tell you a bypass operation of a blocked artery in your thigh is needed to save your foot. This is the reality for far too many people. In the UK, vascular surgeons performed more than 3,500 amputations in 2023.
Panelists discuss how to confirm the diagnosis of atopic dermatitis (AD) when in doubt, emphasizing the importance of clinical evaluation, family history, and skin testing, and share strategies for approaching adult patients with new-onset AD, including thorough patient history and targeted management.
Stroke, Ahead of Print. BACKGROUND:How cerebral microbleeds (CMBs) are formed, and how they cause tissue damage is not fully understood, but it has been suggested they are associated with inflammation, and they could also be related to increased blood-brain barrier (BBB) leakage. We investigated the relationship of CMBs with inflammation and BBB leakage in cerebral small vessel disease, and in particular, whether these 2 processes were increased in the vicinity of CMBs.METHODS:In 54 patients wit
Stroke, Ahead of Print. BACKGROUND:Predicting treated language improvement (TLI) and transfer to the untreated language (cross-language generalization, CLG) after speech-language therapy in bilingual individuals with poststroke aphasia is crucial for personalized treatment planning. This study evaluated machine learning models to predict TLI and CLG and identified the key predictive features (eg, patient severity, demographics, and treatment variables) aligning with clinical evidence.METHODS:For
Walking in a winter wonderland may sound serene and peaceful, but shoveling your sidewalks to take that walk could quickly change delightful to deadly. According to the American Heart Association, the world's leading nonprofit organization focused on heart and brain health for all, research shows that the exertion of shoveling snow may lead to an increased risk of a heart attack or sudden cardiac arrest.
I was sent the ECG shown in Figure-1 told only that this tracing was obtained prior to elective electric cardioversion of a patient who had long been in persistent AFlutter ( A trial F lutter ). Serum electrolytes were normal at the time of cardioversion. The patient tolerated cardioversion well and later that day was discharged from the hospital. ( The post-cardioversion tracing will be shown momentarily in Figure-3 ).
Cardiovascular disease (CVD) and cancer are the two leading causes of death in the U.S. According to researchers from The University of Texas MD Anderson Cancer Center, patients diagnosed with late-stage or metastatic breast cancer have a statistically significant increased risk of pre-diagnosis CVD compared to those with early-stage cancer at diagnosis.
The continuous rise in skin cancer incidence highlights an imperative for improved skin cancer prevention. Topical calcipotriol-plus5-fluorouracil (calcipotriol-plus5-FU) immunotherapy effectively eliminates precancerous skin lesions and prevents squamous cell carcinoma (SCC) in patients. However, its mechanism of action remains unclear. Herein, we demonstrate that calcipotriol-plus5-FU immunotherapy induces T helper type 2 (Th2) immunity, eliminating premalignant keratinocytes in humans.
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