Tue.Nov 19, 2024

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Fitness Level May Offset Genetic Dementia Risk

Med Page Today

(MedPage Today) -- Genetic risk for Alzheimer's disease and dementia appeared to be partly offset by high levels of cardiorespiratory fitness, U.K. Biobank data suggested. Overall, high cardiorespiratory fitness was associated with better global.

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Finding a Role for GLP-1 RAs, Incretin Therapies in Heart Failure, with Muthiah Vaduganathan, MD, MPH

HCPLive

Muthiah Vaduganathan, MD, MPH, discusses the need for cardiology to embrace a role for GLP-1 receptor agonists and incretin therapies, with a focus on obesity-related HFpEF.

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Opioids Tied to Higher Dementia Risk, but Only After a Point

Med Page Today

(MedPage Today) -- After a certain threshold, cumulative opioid use was associated with higher dementia risk, a study of adults over age 60 in Denmark showed. In a nested case-control study, opioid use above 90 total standardized doses (TSDs.

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Is this OMI reperfused or active?

Dr. Smith's ECG Blog

These ECGs were texted to me by one of our previous ultrasound fellows, Will Smoot An elderly male arrived via EMS for acute substernal chest pain with radiation to left shoulder and arm that awakened him from sleep at 0030. He took two full strength aspirin prior to EMS arrival. The pain was relieved by one prehospital NTG spray. He arrived at the ED just shy of two hours after onset, pain free.

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Small Benefit, Persistent Toxic Risk With Adjuvant Anthracycline in Breast Cancer

Med Page Today

(MedPage Today) -- Adding an anthracycline to adjuvant chemotherapy for TOP2A-normal early breast cancer significantly improved disease-free survival (DFS) but not overall survival (OS) at 10 years, and doubled the risk of heart failure, a randomized.

Cancer 89
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Two Studies Assess Echocardiography Evaluation Performance, Relationship Between Markers of Early LV Dysfunction and Mortality in Aortic Regurgitation

American College of Cardiology

American Society of Echocardiography (ASE) guidelines for echocardiographic evaluation of aortic regurgitation (AR) were found to “display very good performance” in detecting significant AR, according to a study published Nov. 13 in JACC: Cardiovascular Imaging.

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Steps to More Accurately Diagnose Oropharyngeal Dysphagia, with Daniel Duncan, MD

HCPLive

At NASPGHAN 2024, HCPLive spoke with Duncan about how treating infants who appear to have reflux may actually result in greater repeat hospital visits.

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Case Report: Diverticulum of the left ventricular outflow tract: multimodal imaging

Frontiers in Cardiovascular Medicine

The left ventricular diverticulum (LVD) is a rare congenital heart disease commonly discovered during examinations. Herein, we report a LVD on the lateral wall of left ventricular outflow tract. A case of a 22-year-old female patient who visited our hospital with complaints of shortness of breath, accompanied by vomiting, cough, and lower limb and facial edema and was diagnosed with “aortopulmonary septal defect” using transthoracic echocardiography.

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More Lp(a)-Reducing Tx; Cardiac Denervation for Afib; LAA Occluders at 5 Years

Med Page Today

(MedPage Today) -- Lipoprotein(a), or Lp(a), was successfully reduced in phase II trials of muvalaplin and zerlasiran. (JAMA) The possibility of a drug interaction between SGLT2 inhibitors and statins was not supported by rates of rhabdomyolysis.

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Transcatheter intervention of modified Blalock–Taussig shunts in patients with hypoplastic left heart syndrome undergoing stage 1 palliation

Frontiers in Cardiovascular Medicine

BackgroundWhile several studies have explored the outcomes of transcatheter interventions for modified Blalock–Taussig shunts (MBTSs) in a broad range of congenital heart diseases, none have specifically examined the interventions in patients with hypoplastic left heart syndrome (HLHS) who underwent Norwood palliation (NP).MethodsThis retrospective study was conducted between 2020 and 2024, when 24 urgent interventions were performed on 17 patients at our center.

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How health systems can meet the 'rising tide' of CVD: 5 notes

Becker's Hospital Review - Cardiology

Hospitals and health systems should be bracing for an 8% and 25% increase in demand for inpatient and outpatient cardiac procedures, respectively, over the next 10 years, according to a new report from Vizient analytic company, Sg2.

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Case Report: Spontaneous recanalization of left anterior descending artery occlusive lesion with OCT-guided drug-coated balloon therapy

Frontiers in Cardiovascular Medicine

In instances where a patient with acute myocardial infarction (AMI) did not undergo immediate reperfusion therapy during the acute phase, there was a risk of the occlusion progressing to chronic and the chances of spontaneous recanalization decreasing. This case report detailed the experience of a 37-year-old male patient who, 45 days post-AMI, still had a blocked left anterior descending (LAD) artery due to the patient's refusal for intervention.

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Optimising remote monitoring for cardiac implantable electronic devices: a UK Delphi consensus

Heart BMJ

Background Remote monitoring (RM) is recommended for the ongoing management of patients with cardiac implantable electronic devices (CIEDs). Despite its benefits, RM adoption has increased the workload for cardiac rhythm management teams. This study used a modified Delphi method to develop a consensus on optimal RM management for adult patients with a CIED in the UK.

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Catheter ablation for atrial tachycardia in pediatric patients: a single-center experience

Frontiers in Cardiovascular Medicine

PurposeAtrial tachycardia is an uncommon supraventricular tachycardia in children. It is often drug-resistant and likely to occur concomitantly with tachycardia-induced cardiomyopathy, making radiofrequency catheter ablation the preferred treatment. The aim of this study was to assess the feasibility, safety, and effectiveness of radiofrequency catheter ablation for the treatment of different types of atrial tachycardia in children, particularly in those with drug-resistant and tachycardia-induc

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Typical dyspnoea and oedema with special ECG changes

Heart BMJ

Clinical introduction The patient is in their 60s and has described experiencing intermittent chest tightness and dyspnoea over the prior 6 months. Four months before this presentation, a 12-lead ECG showed sinus rhythm characterised by a bimodal P-wave and prolonged P-wave duration (117 ms). Echocardiography and laboratory cardiac injury markers were normal.

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Efficacy and safety of sacubitril/valsartan on postoperative atrial fibrillation in adult patients undergoing cardiac surgery: a real-world observational study

Frontiers in Cardiovascular Medicine

BackgroundThe mechanism underlying new-onset postoperative atrial fibrillation (POAF) in adult cardiac surgery is not well understood. However, efficient pharmacological methods to prevent and treat arrhythmic complications are still lacking. In the present study, we explored the efficacy and safety of sacubitril/valsartan (sac/val) in the control of POAF in adult cardiac surgery patients.MethodsBetween January 2021 and December 2021, 667 eligible adult patients who underwent cardiac surgery at

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Long-term prognostic value of contemporary stress echocardiography in patients with suspected or known coronary artery disease: systematic review and meta-analysis

Heart BMJ

Background Long-term outcome of contemporary stress echocardiography has not been systematically assessed. Objective To evaluate the association between results of stress echocardiography and patients’ outcomes with suspected coronary artery disease using randomised controlled trials. Methods Multiple electronic databases were searched for studies evaluating long-term outcome (>12 months) of stress echocardiography in patients suspected of coronary artery disease since year 2000.

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Salvage of cardiopulmonary collapse caused by ethanol sclerotherapy for vascular malformations: clinical experience at a single center and literature review

Frontiers in Cardiovascular Medicine

ObjectiveThis review aims to summarize the salvage experience of cardiopulmonary collapse occurring as a result of absolute ethanol sclerotherapy for vascular malformations.MethodsIn total, we reviewed three cases of cardiopulmonary collapse induced by ethanol sclerotherapy for vascular malformations and described the details of the salvage procedure.

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Managing cardiogenic shock and left ventricular outflow tract obstruction in Takotsubo syndrome: current insights and challenges

Heart BMJ

Over the past decade, Takotsubo syndrome (TTS) has gained increasing recognition as a serious acute cardiovascular condition and now represents an important differential diagnosis in patients with suspected acute coronary syndrome. Current evidence suggests that TTS is likely related to a catecholamine storm leading to coronary microvascular dysfunction in the absence of epicardial coronary artery culprit lesion. 1 Recent studies have demonstrated that the rate of acute complications in TTS is c

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Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

BackgroundEarly coronary angiography (CAG) in post-cardiac arrest patients without ST-segment elevation is a topic of debate. This meta-analysis aimed to assess its impact on outcomes.MethodsA search of Medline and Cochrane up to February 2023 was conducted to identify randomized controlled trials and observational studies comparing patients undergoing early CAG vs. delayed/no CAG after experiencing out-of-hospital cardiac arrest.

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Sudden cardiac death in psychiatric patients: for whom the bell tolls?

Heart BMJ

Psychiatric patients, especially those with severe mental illnesses such as bipolar disorder or schizophrenia, have significantly shorter life expectancy and higher risk of sudden cardiac death (SCD) compared with the general population. For example, in a Danish retrospective cohort study including young patients from 2000 to 2006, the risk of SCD was increased fourfold in patients with psychiatric hospital contact. 1 In this issue of the Heart , Mujkanovic et al report the burden of SCD in an o

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Association of cumulative non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with the risk of cardiometabolic disease

Frontiers in Cardiovascular Medicine

BackgroundOne measurement of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is considered to be associated with insulin resistance and cardiovascular disease (CVD) risk. This study aimed to exploring the association between cumulative non-high-density lipoprotein cholesterol/high-density lipoprotein cholesterol (Cum NHHR) exposure levels and the risk of cardiometabolic disease (CMD).MethodsThis prospective cohort study included 43,735 participants,

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Career Resources

Society of Thoracic Surgeons - Early Career

Career Resources kgilmartin Tue, 11/19/2024 - 11:49 Search By Topics Aspiring CT Surgeons Blog Career Development Career Development Blog Early Career Leadership Image Podcast #170, S4: A Surgeon's Leadership Journey Dr. Steven Gerndt is a cardiothoracic surgeon, speaker, and leadership mentor who developed the concept “Civilitas,” a system-wide cultural transformation focused on psychological safety and fostering of leadership by example.

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Nasal Spray Diuretic Shows Potential for Heart Failure in Trial of Healthy Adults

Med Page Today

(MedPage Today) -- CHICAGO -- A bumetanide nasal spray in development for heart failure was well-tolerated and showed reliable rates of absorption compared with oral and intravenous delivery in a phase I trial of healthy volunteers. The 68-person.

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10 highlights from American Heart Association's Scientific Sessions

Becker's Hospital Review - Cardiology

The American Heart Association held its annual Scientific Sessions Nov. 16-18 in Chicago, where healthcare organizations and industry leaders presented the latest research on cardiovascular health.

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The role of pre-existing left-sided valvular heart disease in the prognosis of patients with acute myocardial infarction

Frontiers in Cardiovascular Medicine

Acute myocardial infarction (AMI) and valvular heart disease (VHD) are the leading causes of cardiovascular morbidity and mortality. The epidemiology of VHD has changed in recent decades with an aging population, increasing risk factors for cardiovascular disease and migration, all of which have a significant implifications for healthcare systems. Due to common pathophysiological mechanisms and risk factors, AMI and VHD often coexist.

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Options for CRC Screening and Need for Patient- Centered Decision-Making

HCPLive

Vivek Kaul, MD, discusses the various options available for colorectal cancer screening, providing an overview of stool-based tests, blood-based tests, colonoscopy, and emerging screening methods.

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Hospitalizations and cardiac sarcoidosis: insights into presentation and diagnosis from the nationwide readmission database

Frontiers in Cardiovascular Medicine

IntroductionCardiac sarcoidosis (CS) is an increasingly recognized cause of cardiac disease. Because the clinical presentation of CS is non-specific, the diagnosis is often delayed. Early detection is essential to initiate treatments that reduce the risk of heart failure (HF) and arrhythmic death. We therefore aimed to describe the features of CS hospitalizations during which the initial diagnosis of CS is made.MethodsWe performed a retrospective analysis of hospitalizations from 2016 to 2019 in

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ACCEL Lite: Key Messages from the ACC Board of Trustees Health Equity Action Plan

American College of Cardiology

In this interview, Drs. Richard Chazal and Paul Douglass discuss Achieving Equitable Cardiovascular Care for All: ACC Board of Trustees Health Equity Task Force Action Plan.

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A deeper look at long-term effects of COVID-19 on myocardial function in survivors with no prior heart diseases: a GRADE approach systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

ObjectivesThe COVID-19 pandemic has challenged global health systems since December 2019, with the novel virus SARS-CoV-2 causing multi-systemic disease, including heart complications. While acute cardiac effects are well-known, long-term implications are understudied. This review hopes to fill a gap in the literature and provide valuable insights into the long-term cardiac consequences of the virus, which can inform future public health policies and clinical practices.MethodsThis systematic rev

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The Six Strategic Goals of the PAD National Action Plan

American College of Cardiology

The 2024 multisociety Guideline for the Management of Lower Extremity Peripheral Artery Disease (PAD) recognizes the implementation of the PAD National Action Plan as a top advocacy priority.

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The correlation between severe asymptomatic carotid artery stenosis and severe multi-organ dysfunction after off-pump coronary artery bypass grafting

Frontiers in Cardiovascular Medicine

BackgroundThe current research aimed to demonstrate the independent association between preoperative severe asymptomatic carotid artery stenosis (ACAS) and severe multi-organ dysfunction after off-pump coronary artery bypass grafting (OPCAB), which may further indicate the relationship between severe ACAS and adverse 30-day postoperative outcomes of patients undergoing OPCAB.MethodsThis was a single-center, retrospective observational study including patients without a history of stroke or Trans

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Safety Data on Dupilumab, Ensifentrine for COPD, with MeiLan Han, MD

HCPLive

This segment of Han’s interview featured a discussion of the safety profile of dupilumab and ensifentrine, as well as other details in the GOLD 2025 Report.

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Prevention and control of cardiovascular disease in “real-world” settings: sustainable implementation of effective policies

Frontiers in Cardiovascular Medicine

Global progress in addressing cardiovascular diseases (CVD) has been insufficient to attain the nine WHO non-communicable disease (NCD) targets and the Sustainable Development Goal (SDG) target of reducing premature NCD mortality by one-third by 2030. Progress has been slowest in low- and middle-income countries (LMIC) where addressing the CVD burden is a foremost development imperative.

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Navigating News and Updates in Cardiology at AHA 24, with Viet Le, PA-C, DMSc

HCPLive

Viet Le, PA-C, DMSc, breaks down new data and updates from AHA 24, spotlighting 3 specific trials and the applicability of artificial intelligence in care.

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Intraoperative Conduction Mapping in Complex Congenital Heart Disease

American College of Cardiology

What is the impact of intraoperative His bundle (HB) mapping during complex biventricular congenital heart disease (CHD) repair on postoperative atrioventricular block requiring pacemaker (AVB/PM)?

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Positive Phase 3 Results Announced for JNJ-2113 Treatment of Psoriasis

HCPLive

These data were announced by Protagonist Therapeutics, resulting from the 2 pivotal ICONIC-LEAD and ICONIC-TOTAL studies on the oral peptide icotrokinra.

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