Fri.Jul 05, 2024

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Popular Diabetes Drug Class Lowered Risk of 10 Obesity-Associated Cancers

Med Page Today

(MedPage Today) -- GLP-1 receptor agonists lowered the risk of several obesity-associated cancers, a retrospective analysis of electronic health records suggested. Compared with insulin, GLP-1s were associated with a lower risk for developing.

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Chronic Tonsillitis Associated with Increased Risk of IgA Nephropathy

HCPLive

Patients with chronic tonsillitis had greater IgAN event rates than those without, and further analysis revealed chronic tonsillitis was linked to a greater risk of developing IgAN.

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Regular Wide Complex Tachycarida with poor LV function and hypotension. Duration unknown. How to manage?

Dr. Smith's ECG Blog

An older patient with no previous medical history arrived at triage complaining of SOB. Her heart rate was very fast, so we obtained an ECG immediately: ECG: What do you think? There is a regular wide complex tachycardia. The QRS morphology is RBBB with LAFB (tiny r-waves in inferior leads followed by deep S-waves; tiny q-wave in aVL followed by large R-wave; Left axis deviation).

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Why Your Blood Pressure Probably Isn't Normal & What You Need To Do About It.

Dr. Paddy Barrett

We do a terrible job of identifying and managing high blood pressure. We can send spacecraft across the solar system. We have managed to harness the power of the atom. And we still do an awful job of identifying and managing high blood pressure. Here’s why. And what to do about it. The Scale Of The Problem. As a risk factor for death, high blood pressure is responsible for more deaths than any other risk factor, including smoking.

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Reversing racism's toll on heart health

Medical Xpress - Cardiology

Researchers from Mayo Clinic and the University of Minnesota have published a paper in the Journal of Clinical and Translational Science, which provides a new framework describing how racism affects heart health among people of color in Minnesota. The researchers are focused on reversing these disparities.

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Physiology Friday #225: Resistance Training at an Old Age Has Lasting Strength Benefits

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Biosimilars Month in Review: June 2024

HCPLive

The biosimilars month in review underscores the efficacy and safety of biosimilars in rheumatology, including recent studies supporting the growing confidence in these treatments across disease spaces.

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JAK Inhibitor Updates: Upadacitinib and the Level-Up Trial

HCPLive

Raj Chovatiya, MD, PhD, MSCI, and Lawrence Eichenfield, MD, review a recent trial comparing upadacitinib to dupilumab for patients with atopic dermatitis.

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Patient-specific 3D in vitro modeling and fluid dynamic analysis of primary pulmonary vein stenosis

Frontiers in Cardiovascular Medicine

IntroductionPrimary pulmonary vein stenosis (PVS) is a rare congenital heart disease that proves to be a clinical challenge due to the rapidly progressive disease course and high rates of treatment complications. PVS intervention is frequently faced with in-stent restenosis and persistent disease progression despite initial venous recanalization with balloon angioplasty or stenting.

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FDA Approves Prefilled Syringe of Faricimab (Vabysmo) for AMD, DME, and RVO

HCPLive

Announced by Genentech on July 04, 2024, the prefilled, 6.0 mg syringe is designed to improve ease of administration and offer ophthalmologists with a ready-to-use version of the bispecific antibody.

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Enhancing ECG-based heart age: impact of acquisition parameters and generalization strategies for varying signal morphologies and corruptions

Frontiers in Cardiovascular Medicine

Electrocardiogram (ECG) is a non-invasive approach to capture the overall electrical activity produced by the contraction and relaxation of the cardiac muscles. It has been established in the literature that the difference between ECG-derived age and chronological age represents a general measure of cardiovascular health. Elevated ECG-derived age strongly correlates with cardiovascular conditions (e.g., atherosclerotic cardiovascular disease).

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Endocrinology Month in Review: June 2024

HCPLive

In the endocrinology month in review, we spotlight top news in the endocrinology pipeline and the most important updates from ADA 2024.

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Cognitive biases in pediatric cardiac care

Frontiers in Cardiovascular Medicine

Medical practitioners are entrusted with the pivotal task of making optimal decisions in healthcare delivery. Despite rigorous training, our confidence in reasoning can fail when faced with pressures, uncertainties, urgencies, difficulties, and occasional errors. Day-to-day decisions rely on swift, intuitive cognitive processes known as heuristic or type 1 decision-making, which, while efficient in most scenarios, harbor inherent vulnerabilities leading to systematic errors.

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Researchers investigate why aortic aneurysms form at the arch or in the abdominal segment

Medical Xpress - Cardiology

A vascular dilatation in the aorta can be life-threatening if it bursts. These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the abdominal cavity.

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Case Report: Vasospastic angina presenting as phantom odor perception

Frontiers in Cardiovascular Medicine

BackgroundVasospastic angina usually presents with intermittent episodes of chest pain. It can rarely be associated with the perception of phantom odors.Case summaryA 69-year-old woman presented for evaluation of intermittent shortness of breath and chest pain. She reported that she often experienced an abnormal smell sensation just prior to the event.

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Air Pollution and Stroke: What Nurses Need to Know

Stroke Journal

Stroke, Ahead of Print. Air pollution exposure is linked to an increased risk of stroke. Elevated levels of pollution (carbon monoxide, carbon dioxide, nitrous oxide, sulfur dioxide, coarse particulate matter [PM10], and especially fine particulate matter [PM2.5]) cause systemic inflammation after the particles are inhaled and lodge into lung tissue, causing an increased incidence of stroke, hospitalizations for stroke, and stroke mortality.

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Thromboaspiration of a left-sided bioprosthetic valve thrombosis by a mini-access: the Lausanne novel procedure

Frontiers in Cardiovascular Medicine

Left-sided bioprosthesis valve thrombosis (LSBVT) is a challenging complication necessitating invasive interventions. In this study, we introduce a novel, minimally invasive approach. We used a cerebral embolic protection system and an Occlutech cannula connected to an extracorporeal circuit, providing safer thrombus aspiration compared to the AngioVac system.

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Use of Direct Oral Anticoagulants in Patients with Peripheral Artery Disease: A Meta-Analysis

The American Journal of Cardiology

Publication date: Available online 3 July 2024 Source: The American Journal of Cardiology Author(s): Asmaa Ahmed, Mohamed Hamed, Ahmed Abozaid, Ahmed Elkheshen, Mark Fisher, Wissam Khalife, Hani Jneid, Subhash Banerjee, Ayman Elbadawi

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Patient-specific in silico 3D coronary model in cardiac catheterisation laboratories

Frontiers in Cardiovascular Medicine

Coronary artery disease is caused by the buildup of atherosclerotic plaque in the coronary arteries, affecting the blood supply to the heart, one of the leading causes of death around the world. X-ray coronary angiography is the most common procedure for diagnosing coronary artery disease, which uses contrast material and x-rays to observe vascular lesions.

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Clinical Efficacy of Permanent Internal Mammary Artery Occlusion in Chronic Coronary Syndrome: a Double-Blind, Randomized, Sham-Controlled Trial

The American Journal of Cardiology

Publication date: Available online 3 July 2024 Source: The American Journal of Cardiology Author(s): Marius Reto Bigler, Andrea Kieninger-Gräfitsch, Christine Tschannen, Raphael Grossenbacher, Christian Seiler

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Performance of federated learning-based models in the Dutch TAVI population was comparable to central strategies and outperformed local strategies

Frontiers in Cardiovascular Medicine

BackgroundFederated learning (FL) is a technique for learning prediction models without sharing records between hospitals. Compared to centralized training approaches, the adoption of FL could negatively impact model performance.AimThis study aimed to evaluate four types of multicenter model development strategies for predicting 30-day mortality for patients undergoing transcatheter aortic valve implantation (TAVI): (1) central, learning one model from a centralized dataset of all hospitals; (2)

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Land of Confusion

The American Journal of Cardiology

Publication date: Available online 10 July 2007 Source: The American Journal of Cardiology Author(s): Hector O.

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CCTA-Derived Inflammatory Markers and Cardiac Risk in Patients Without Obstructive CAD

NEJM Journal Watch - Cardiology

Markers derived from computed tomography of the coronary arteries helped predict cardiovascular risk.

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Women-Specific Goalposts Urged for Coronary Bypass Surgery

Med Page Today

(MedPage Today) -- Gender disparities in outcomes after coronary artery bypass grafting (CABG) might be addressed by sex-specific biomarker thresholds for perioperative myocardial injury, researchers suggested from a retrospective study. Compared.