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BackgroundPercutaneous extracorporeal membrane oxygenation (ECMO) is administered to pediatric patients with cardiogenic shock or cardiac arrest. The traditional method uses focal echocardiography to complete the left ventricular measurement. However, echocardiographic determination of the ejection fraction (EF) by manual tracing of the endocardial borders is time consuming and operator dependent.
Scientists have made a significant breakthrough in understanding how 'bad' cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptor -- a process that starts the clearing of LDL from the blood -- and what happens when that process gets impaired.
Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, predisposes individuals to aortic stenosis and regurgitation due to valve degeneration. Abnormal hemodynamics, arterial wall characteristics, and genetic factors contribute to ascending aorta dilatation, potentially leading to severe complications like aortic dissection. Presently, the most recent guidelines propose that individuals with BAV requiring valve replacement due to valve dysfunction should undergo simultaneous re
Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
In harmonic imaging, if the frequency of ultrasound transmitted is 2.5 MHz, reception is on: A. 4 MHz B. 5 MHz C. 6 MHz D. 7 MHz Correct answer: B. 5 MHz If the transmit and receive frequency are the same in echocardiography, the image quality may be poorer because of higher levels interference and artifacts. In harmonic imaging, reception is on the second harmonic frequency, like 5MHz for a 2.5 MHz transmitted signal, interference and artifacts are lesser, resulting in better image quality.
The majority of children who started smoking tobacco at age 10 years or in their later teens continued to smoke until their mid-twenties. Continuous smoking from childhood significantly increased the risk of premature heart damage, a new study shows.
National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptora process that starts the clearing of LDL from the bloodand what happens when that process gets impaired.
(MedPage Today) -- A recent New York Times story described a new fad: "microdosing" GLP-1 anti-obesity drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). I was asked to discuss the topic on CBS News recently, which gave.
Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in JAMA Cardiology.
A 50-year-old woman presented with a 5-year history of xanthogranulomas under her eyes. Laboratory studies were notable for thrombocytopenia and very high levels of low-density lipoprotein cholesterol.
The following are key points to remember from a state-of-the-art review on revisiting implantable cardioverter-defibrillator (ICD) therapy for primary prevention in patients with heart failure and reduced ejection fraction (HFrEF).
In a trial of percutaneous coronary intervention or conservative treatment in patients undergoing TAVI, PCI was associated with a lower risk of a composite of death, MI, or urgent revascularization at a median of 2 years.
The majority of children who started smoking tobacco at age 10 years or in their later teens continued to smoke until their mid-twenties. Continuous smoking from childhood significantly increased the risk of premature heart damage, a new study shows. The study was conducted in collaboration between the Universities of Bristol and Exeter in the UK, and the University of Eastern Finland, and the results were published in the Journal of the American College of Cardiology (JACC).
Abstract Worldwide, valvular heart disease (VHD) is a common cause of hospitalization for acute heart failure. In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock. Current evidence remains scarce and recommendations regarding the management of acute heart failure caused by VHD are lacking in most recent international guidelines.
A phase 1 trial of nexiguran ziclumeran (nex-z) to treat transthyretin cardiomyopathy showed a rapid and durable reduction of 90% in serum transthyretin levels and evidence of disease stabilization.
This analysis involved assessing rates of lifetime as well as prior 12-month treatment use for AUD, in addition to demographic and clinical characteristics linked to AUD treatment.
DALLAS, Dec 11, 2025 A stroke can happen to anyone at any age. Actor and comedian Jamie Foxx recently shared in his Netflix special "What Had Happened Was," that he experienced a brain bleed. Reports of this experience highlight the importance of.
Transcatheter aortic-valve implantation (TAVI) emerged as a disruptive, revolutionary approach for treating patients with aortic stenosis.1 However, how we should approach catheter-based therapy in patients with concomitant stable coronary artery disease, which affects approximately 50% of candidates for TAVI, has remained a clinical conundrum. Should we mimic.
Tobacco smoking from ages 10 to 24 years was associated with a 33% to 52% odds of premature structural and functional cardiac injury, according to a new study published in JACC. Furthermore, smoking from childhood through early adulthood was also associated with cardiac mass increase, with one-third of the effect estimate retained after controlling for risk factors.
Patients taking immunosuppressive and hepatitis B antiviral drugs after living donor liver transplant had lower antibody response to COVID-19 vaccination.
A new study assessing provincial and territorial variations in reimbursement criteria of drug coverage for patients covered by Canada's public pharmacare programs for two common cardiovascular conditions revealed significant inequities and deficiencies in access to medications and treatment.
Experts agree more care should be given to cardiovascular safety concerns during clinical cancer trials. The Cardiovascular Safety Research Consortium published new recommendations for addressing those concerns Dec. 10 in JACC: CardioOncology.
The American College of Cardiology has developed an Expert Consensus Decision Pathway for the diagnosis and management of adult patients with acute myocarditis. The pathway was published Dec. 10 in the Journal of the American College of Cardiology.
In part 3 of 4 from this episode, the discussion focuses on establishing surrogate endpoints for clinical trials in focal segmental glomerulosclerosis.
(MedPage Today) -- Note that some links may require registration or subscription. Jamie Foxx revealed details about his 2023 near-death experience, saying he had a brain bleed and stroke that left him in a coma for 20 days. (CBS News) The H5N1.
In the final segment of this episode, the discussion focuses on next steps for the PARASOL Initiative and its potential to transform FSGS drug development.
Greetings! For today’s post, I’m sharing (with permission) my appearance on the Life in Stride podcast, hosted by a few good friends and outstanding runners. Here’s the episode description and links to their content. Please give them a follow/subscribe! On this episode, the boys had on special guest Brady Holmer! The best way to describe Brady would be an expert in the science of running and human performance.
Having a quality breakfast that provides the right amount of energy to face the day, around a quarter of daily intake, reduces the risk of cardiovascular disease.
The panel of experts discuss the role of effectively treating pruritus, a common and debilitating symptom in over 80% of patients with cholestatic liver diseases like primary biliary cholangitis (PBC), and its importance in the long-term management of the disease.
Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which proceeds slowly and cannot be directly attributed to hypertension or other cardiovascular disorders. This often under-diagnosed heart function impairment is one of the leading causes of death in diabetic patients and it affects both type 1 and type 2 diabetics.
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