Science Daily - Heart Disease
DECEMBER 11, 2024
Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.
HCPLive
DECEMBER 11, 2024
Samelson-Jones discussed follow-up data of up to 6 years with investigations of fidanacogene elaparvovec.
Med Page Today
DECEMBER 11, 2024
(MedPage Today) -- A recent New York Times story described a new fad: "microdosing" GLP-1 anti-obesity drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). I was asked to discuss the topic on CBS News recently, which gave.
HCPLive
DECEMBER 11, 2024
Investigators developed and validated a novel model to identify liver fibrosis in patients with diabetes which performed better than existing models.
Science Daily - Heart Disease
DECEMBER 11, 2024
The majority of children who started smoking tobacco at age 10 years or in their later teens continued to smoke until their mid-twenties. Continuous smoking from childhood significantly increased the risk of premature heart damage, a new study shows.
The New England Journal of Medicine
DECEMBER 11, 2024
A 50-year-old woman presented with a 5-year history of xanthogranulomas under her eyes. Laboratory studies were notable for thrombocytopenia and very high levels of low-density lipoprotein cholesterol.
American College of Cardiology
DECEMBER 11, 2024
The following are key points to remember from a state-of-the-art review on revisiting implantable cardioverter-defibrillator (ICD) therapy for primary prevention in patients with heart failure and reduced ejection fraction (HFrEF).
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Medical Xpress - Cardiology
DECEMBER 11, 2024
National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptora process that starts the clearing of LDL from the bloodand what happens when that process gets impaired.
HCPLive
DECEMBER 11, 2024
In part 1 of 4 from this episode, the discussion focuses on the backgrounds of guests Laura Mariani, MD, MS, and Daniel Gale, PhD, MB BChir.
Science Daily - Heart Disease
DECEMBER 11, 2024
Scientists have made a significant breakthrough in understanding how 'bad' cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptor -- a process that starts the clearing of LDL from the blood -- and what happens when that process gets impaired.
American Heart News - Stroke News
DECEMBER 11, 2024
DALLAS, Dec 11, 2025 A stroke can happen to anyone at any age. Actor and comedian Jamie Foxx recently shared in his Netflix special "What Had Happened Was," that he experienced a brain bleed. Reports of this experience highlight the importance of.
HCPLive
DECEMBER 11, 2024
Bernaudin discussed the Drepagreffe-1 and 2 studies and improvements seen over 10 years of follow-up.
American College of Cardiology
DECEMBER 11, 2024
Tobacco smoking from ages 10 to 24 years was associated with a 33% to 52% odds of premature structural and functional cardiac injury, according to a new study published in JACC. Furthermore, smoking from childhood through early adulthood was also associated with cardiac mass increase, with one-third of the effect estimate retained after controlling for risk factors.
HCPLive
DECEMBER 11, 2024
This analysis involved assessing rates of lifetime as well as prior 12-month treatment use for AUD, in addition to demographic and clinical characteristics linked to AUD treatment.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
BackgroundPercutaneous extracorporeal membrane oxygenation (ECMO) is administered to pediatric patients with cardiogenic shock or cardiac arrest. The traditional method uses focal echocardiography to complete the left ventricular measurement. However, echocardiographic determination of the ejection fraction (EF) by manual tracing of the endocardial borders is time consuming and operator dependent.
HCPLive
DECEMBER 11, 2024
Patients taking immunosuppressive and hepatitis B antiviral drugs after living donor liver transplant had lower antibody response to COVID-19 vaccination.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
ObjectiveInflammatory factors play a crucial role in the onset and progression of heart failure. To further explore the causal relationship between inflammatory factors and heart failure, we employed bidirectional Mendelian randomization analysis to investigate the causal links between 91 inflammatory cytokines and heart failure.MethodsWe conducted our study using the bidirectional Mendelian randomization approach.
Medical Xpress - Cardiology
DECEMBER 11, 2024
A new study assessing provincial and territorial variations in reimbursement criteria of drug coverage for patients covered by Canada's public pharmacare programs for two common cardiovascular conditions revealed significant inequities and deficiencies in access to medications and treatment.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
ObjectiveTo investigate the causal relationship between 233 newly reported metabolites and coronary atherosclerosis through Mendelian randomization analysis.MethodsFive different methods were used to perform Mendelian randomization analysis on the 233 metabolites and coronary atherosclerosis, with inverse variance weighting as the primary result, supplemented by other methods.ResultsThe analysis identified that certain metabolites increase the susceptibility risk of coronary atherosclerosis, inc
Becker's Hospital Review - Cardiology
DECEMBER 11, 2024
Experts agree more care should be given to cardiovascular safety concerns during clinical cancer trials. The Cardiovascular Safety Research Consortium published new recommendations for addressing those concerns Dec. 10 in JACC: CardioOncology.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, predisposes individuals to aortic stenosis and regurgitation due to valve degeneration. Abnormal hemodynamics, arterial wall characteristics, and genetic factors contribute to ascending aorta dilatation, potentially leading to severe complications like aortic dissection. Presently, the most recent guidelines propose that individuals with BAV requiring valve replacement due to valve dysfunction should undergo simultaneous re
HCPLive
DECEMBER 11, 2024
This 4-part episode focuses on the PARASOL Initiative and the landscape of focal segmental glomerulosclerosis treatment.
Becker's Hospital Review - Cardiology
DECEMBER 11, 2024
The American College of Cardiology has developed an Expert Consensus Decision Pathway for the diagnosis and management of adult patients with acute myocarditis. The pathway was published Dec. 10 in the Journal of the American College of Cardiology.
HCPLive
DECEMBER 11, 2024
In part 3 of 4 from this episode, the discussion focuses on establishing surrogate endpoints for clinical trials in focal segmental glomerulosclerosis.
Med Page Today
DECEMBER 11, 2024
(MedPage Today) -- Note that some links may require registration or subscription. Jamie Foxx revealed details about his 2023 near-death experience, saying he had a brain bleed and stroke that left him in a coma for 20 days. (CBS News) The H5N1.
HCPLive
DECEMBER 11, 2024
In the final segment of this episode, the discussion focuses on next steps for the PARASOL Initiative and its potential to transform FSGS drug development.
Physiologically Speaking
DECEMBER 11, 2024
Greetings! For today’s post, I’m sharing (with permission) my appearance on the Life in Stride podcast, hosted by a few good friends and outstanding runners. Here’s the episode description and links to their content. Please give them a follow/subscribe! On this episode, the boys had on special guest Brady Holmer! The best way to describe Brady would be an expert in the science of running and human performance.
HCPLive
DECEMBER 11, 2024
In this study, investigators described the safety and tolerability of BLV therapy following 48weeks of therapy among those with CHD.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
BackgroundCardiovascular biomarkers are crucial for monitoring cancer therapy-related cardiac toxicity, but the effects on early stage are still inadequate. To screen biomarkers in patients with breast cancer who receive anthracycline-containing chemotherapy, we studied the behavior of six biomarkers during chemotherapy and their association with chemotherapy-related cardiac toxicity.MethodsIn a prospective cohort of 73 patients treated with anthracycline-containing chemotherapy, soluble suppres
HCPLive
DECEMBER 11, 2024
The panel of experts discuss the role of effectively treating pruritus, a common and debilitating symptom in over 80% of patients with cholestatic liver diseases like primary biliary cholangitis (PBC), and its importance in the long-term management of the disease.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
IntroductionPatients with acute myocardial infarction (AMI) are at high risk of progressing to heart failure (HF). Recent research has shown that lipid droplet-related genes (LDRGs) play a crucial role in myocardial metabolism following MI, thereby influencing the progression to HF.MethodsWeighted gene co-expression network analysis (WGCNA) and differential expression gene analysis were used to screen a transcriptome dataset of whole blood cells from AMI patients with (AMI HF, n=16) and without
HCPLive
DECEMBER 11, 2024
The panel of experts examine the long-term data for the recently FDA-approved PPAR- agonist elafibranor in the treatment of primary biliary cholangitis (PBC), comparing its clinical findings with those of seladelpar, and explores how to choose the right peroxisome proliferator-activated receptor (PPAR) agonist and assess treatment effectiveness.
Frontiers in Cardiovascular Medicine
DECEMBER 11, 2024
BackgroundHypertension can damage multiple target organs. The younger the age of onset of hypertension is, the greater the risk of cardiovascular disease (CVD) and cardiovascular death. Chronic kidney disease (CKD) is a complication of hypertension, but few studies have investigated the relationship between the age of onset of hypertension and CKD.ObjectiveWe investigated the relationship between the age of onset of hypertension and CKD.MethodWe analyzed data from the National Health and Nutriti
HCPLive
DECEMBER 11, 2024
Panelists discuss how antihypertensive treatment encompasses multiple drug classes with distinct mechanisms of action, alongside lifestyle modifications such as dietary changes and exercise, providing a comprehensive approach to blood pressure management.
Medical Xpress - Cardiology
DECEMBER 11, 2024
Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in JAMA Cardiology.
HCPLive
DECEMBER 11, 2024
Panelists discuss how antihypertensive treatment encompasses multiple drug classes with distinct mechanisms of action, alongside lifestyle modifications such as dietary changes and exercise, providing a comprehensive approach to blood pressure management.
All About Cardiovascular System and Disorders
DECEMBER 11, 2024
In harmonic imaging, if the frequency of ultrasound transmitted is 2.5 MHz, reception is on: A. 4 MHz B. 5 MHz C. 6 MHz D. 7 MHz Correct answer: B. 5 MHz If the transmit and receive frequency are the same in echocardiography, the image quality may be poorer because of higher levels interference and artifacts. In harmonic imaging, reception is on the second harmonic frequency, like 5MHz for a 2.5 MHz transmitted signal, interference and artifacts are lesser, resulting in better image quality.
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